
NATURE . COM {
}
Title:
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay | Nature Structural & Molecular Biology
Description:
The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1–7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3′ end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3′ end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1–7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3′ oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Education
- Science
- Telecommunications
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌆 Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,556,742 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$536,300 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $357,519 to $983,176.
Keywords {🔍}
article, google, scholar, cas, histone, nature, mrna, cell, mrnas, biol, mol, rna, eri, access, stemloop, nat, marzluff, end, content, molecular, biology, cookies, data, decay, mouse, degradation, struct, decapping, research, privacy, processing, structural, rath, stem, conserved, yeast, uridylation, institute, function, information, replicationdependent, nicola, heinz, ansel, heissmeyer, cells, open, gene, microrna, exonuclease,
Topics {✒️}
nature portfolio permissions reprints privacy policy mouse lymphocyte development german research foundation advertising cancer research social media nature 427 nature 404 nature double-stranded stem-loop structure eri1-deficient mouse cells induce replication-dependent decay conserved c-terminal sequence heterochromatin-dependent gene silencing complex protein-dna dynamics flag-ha-heri1 construct author correspondence replication-linked histone genes stem-loop binding protein springerlink instant access u-rich rna vigo heissmeyer mammalian histone pre-mrna zcchc11-dependent uridylation targets argonaute proteins permissions farm animal biology double-stranded stem gene silencing factor personal data general translational repression roquin promotes recognition stem-loop structure privacy conserved dual role oligouridylated histone mrnas dna replication type elisabeth kremmer lsm1–7 heteroheptamer recognizes probable regulatory roles present address competing financial interests mature histone mrnas cytoplasmic rna data protection data demonstrate histone mrna stability mouse eri1 interacts
Schema {🗺️}
WebPage:
mainEntity:
headline:Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay
description:The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1â7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3â² end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3â² end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1â7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3â² oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
datePublished:2012-12-02T00:00:00Z
dateModified:2012-12-02T00:00:00Z
pageStart:73
pageEnd:81
sameAs:https://doi.org/10.1038/nsmb.2450
keywords:
RNA decay
Structural biology
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig7_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
type:Person
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
type:Person
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay
description:The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1â7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3â² end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3â² end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1â7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3â² oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
datePublished:2012-12-02T00:00:00Z
dateModified:2012-12-02T00:00:00Z
pageStart:73
pageEnd:81
sameAs:https://doi.org/10.1038/nsmb.2450
keywords:
RNA decay
Structural biology
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig7_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
type:Person
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
type:Person
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(107)
- What is the earnings of https://link.springer.com/article/10.1038/nsmb.2450?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- How much does https://doi.org/10.1038%2Fnature02302 gross monthly?
- How much money does http://scholar.google.com/scholar_lookup?&title=A%20conserved%20siRNA-degrading%20RNase%20negatively%20regulates%20RNA%20interference%20in%20C.%20elegans&journal=Nature&doi=10.1038%2Fnature02302&volume=427&pages=645-649&publication_year=2004&author=Kennedy%2CS&author=Wang%2CD&author=Ruvkun%2CG generate?
- What are the earnings of https://doi.org/10.1016%2Fj.cub.2006.05.061?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Conserved%20ribonuclease%2C%20Eri1%2C%20negatively%20regulates%20heterochromatin%20assembly%20in%20fission%20yeast&journal=Curr.%20Biol.&doi=10.1016%2Fj.cub.2006.05.061&volume=16&pages=1459-1464&publication_year=2006&author=Iida%2CT&author=Kawaguchi%2CR&author=Nakayama%2CJ each month?
- What's the financial intake of https://doi.org/10.1016%2Fj.cell.2006.04.025?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Tethering%20RITS%20to%20a%20nascent%20transcript%20initiates%20RNAi-%20and%20heterochromatin-dependent%20gene%20silencing&journal=Cell&doi=10.1016%2Fj.cell.2006.04.025&volume=125&pages=873-886&publication_year=2006&author=B%C3%BChler%2CM&author=Verdel%2CA&author=Moazed%2CD
- How much money does https://doi.org/10.1182%2Fblood-2011-11-394072 generate?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Eri1%20regulates%20microRNA%20homeostasis%20and%20mouse%20lymphocyte%20development%20and%20antiviral%20function&journal=Blood&doi=10.1182%2Fblood-2011-11-394072&volume=120&pages=130-142&publication_year=2012&author=Thomas%2CMF
- Get to know https://doi.org/10.1038%2Fnsmb.1411's earnings
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=The%20exonuclease%20ERI-1%20has%20a%20conserved%20dual%20role%20in%205.8S%20rRNA%20processing%20and%20RNAi&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1411&volume=15&pages=531-533&publication_year=2008&author=Gabel%2CHW&author=Ruvkun%2CG?
- How much revenue does https://doi.org/10.1038%2Fnsmb.1417 bring in?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Mouse%20Eri1%20interacts%20with%20the%20ribosome%20and%20catalyzes%205.8S%20rRNA%20processing&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1417&volume=15&pages=523-530&publication_year=2008&author=Ansel%2CKM
- How much money does https://doi.org/10.1016%2FS1097-2765%2803%2900278-8 generate?
- http://scholar.google.com/scholar_lookup?&title=A%203%E2%80%B2%20exonuclease%20that%20specifically%20interacts%20with%20the%203%E2%80%B2%20end%20of%20histone%20mRNA&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2803%2900278-8&volume=12&pages=295-305&publication_year=2003&author=Dominski%2CZ&author=Yang%2CXC&author=Kaygun%2CH&author=Dadlez%2CM&author=Marzluff%2CWF income
- What's the total monthly financial gain of https://doi.org/10.1074%2Fjbc.M602947200?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Characterization%20of%203%E2%80%B2hExo%2C%20a%203%E2%80%B2%20exonuclease%20specifically%20interacting%20with%20the%203%E2%80%B2%20end%20of%20histone%20mRNA&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M602947200&volume=281&pages=30447-30454&publication_year=2006&author=Yang%2CXC&author=Purdy%2CM&author=Marzluff%2CWF&author=Dominski%2CZ?
- Learn how profitable https://doi.org/10.1017%2FS1355838201001820 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=The%20stem-loop%20binding%20protein%20forms%20a%20highly%20stable%20and%20specific%20complex%20with%20the%203%E2%80%B2%20stem-loop%20of%20histone%20mRNAs&journal=RNA&doi=10.1017%2FS1355838201001820&volume=7&pages=123-132&publication_year=2001&author=Battle%2CDJ&author=Doudna%2CJA earn?
- How much does https://doi.org/10.1093%2Fnar%2F28.7.1594 make?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Positive%20and%20negative%20mutant%20selection%20in%20the%20human%20histone%20hairpin-binding%20protein%20using%20the%20yeast%20three-hybrid%20system&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F28.7.1594&volume=28&pages=1594-1603&publication_year=2000&author=Martin%2CF&author=Michel%2CF&author=Zenklusen%2CD&author=Muller%2CB&author=Schumperli%2CD
- How much does https://doi.org/10.1093%2Fnar%2F23.4.654 pull in?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20sequence%20of%20the%20stem%20and%20flanking%20sequences%20at%20the%203%E2%80%B2%20end%20of%20histone%20mRNA%20are%20critical%20determinants%20for%20the%20binding%20of%20the%20stem-loop%20binding%20protein&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F23.4.654&volume=23&pages=654-662&publication_year=1995&author=Williams%2CAS&author=Marzluff%2CWF produce monthly?
- What's the financial outcome of https://doi.org/10.1128%2FMCB.00296-09?
- How much does http://scholar.google.com/scholar_lookup?&title=Three%20proteins%20of%20the%20U7-specific%20Sm%20ring%20function%20as%20the%20molecular%20ruler%20to%20determine%20the%20site%20of%203%E2%80%B2-end%20processing%20in%20mammalian%20histone%20pre-mRNA&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.00296-09&volume=29&pages=4045-4056&publication_year=2009&author=Yang%2CXC&author=Torres%2CMP&author=Marzluff%2CWF&author=Dominski%2CZ make?
- https://doi.org/10.1006%2Fgeno.2002.6850's financial summary
- Income figures for http://scholar.google.com/scholar_lookup?&title=The%20human%20and%20mouse%20replication-dependent%20histone%20genes&journal=Genomics&doi=10.1006%2Fgeno.2002.6850&volume=80&pages=487-498&publication_year=2002&author=Marzluff%2CWF&author=Gongidi%2CP&author=Woods%2CKR&author=Jin%2CJ&author=Maltais%2CLJ
- How much does https://doi.org/10.1016%2F0092-8674%2886%2990483-6 make?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Normal%20stoichiometry%20of%20histone%20dimer%20sets%20is%20necessary%20for%20high%20fidelity%20of%20mitotic%20chromosome%20transmission&journal=Cell&doi=10.1016%2F0092-8674%2886%2990483-6&volume=44&pages=43-52&publication_year=1986&author=Meeks-Wagner%2CD&author=Hartwell%2CLH
- How much income does https://doi.org/10.1016%2F0092-8674%2887%2990240-6 have?
- How much money does http://scholar.google.com/scholar_lookup?&title=Translation%20is%20required%20for%20regulation%20of%20histone%20mRNA%20degradation&journal=Cell&doi=10.1016%2F0092-8674%2887%2990240-6&volume=48&pages=615-626&publication_year=1987&author=Graves%2CRA&author=Pandey%2CNB&author=Chodchoy%2CN&author=Marzluff%2CWF make?
- See how much https://doi.org/10.1128%2FMCB.7.12.4557 makes per month
- How much profit does http://scholar.google.com/scholar_lookup?&title=The%20stem-loop%20structure%20at%20the%203%E2%80%B2%20end%20of%20histone%20mRNA%20is%20necessary%20and%20sufficient%20for%20regulation%20of%20histone%20mRNA%20stability&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.7.12.4557&volume=7&pages=4557-4559&publication_year=1987&author=Pandey%2CNB&author=Marzluff%2CWF make?
- Income figures for https://doi.org/10.1038%2Fnsmb724
- How much profit is http://scholar.google.com/scholar_lookup?&title=The%20enzymes%20and%20control%20of%20eukaryotic%20mRNA%20turnover&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb724&volume=11&pages=121-127&publication_year=2004&author=Parker%2CR&author=Song%2CH making per month?
- How much money does https://doi.org/10.1016%2FS1097-2765%2801%2900395-1 make?
- How much money does http://scholar.google.com/scholar_lookup?&title=Targeting%20an%20mRNA%20for%20decapping%3A%20displacement%20of%20translation%20factors%20and%20association%20of%20the%20Lsm1p-7p%20complex%20on%20deadenylated%20yeast%20mRNAs&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2801%2900395-1&volume=8&pages=1075-1083&publication_year=2001&author=Tharun%2CS&author=Parker%2CR make?
- Learn how profitable https://doi.org/10.1016%2FS0092-8674%2801%2900592-X is on a monthly basis
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Functional%20link%20between%20the%20mammalian%20exosome%20and%20mRNA%20decapping&journal=Cell&doi=10.1016%2FS0092-8674%2801%2900592-X&volume=107&pages=751-762&publication_year=2001&author=Wang%2CZ&author=Kiledjian%2CM?
- How much does https://doi.org/10.1101%2Fgad.1622708 gross monthly?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20histone%20mRNA%20requires%20oligouridylation%20followed%20by%20decapping%20and%20simultaneous%20degradation%20of%20the%20mRNA%20both%205%E2%80%B2%20to%203%E2%80%B2%20and%203%E2%80%B2%20to%205%E2%80%B2&journal=Genes%20Dev.&doi=10.1101%2Fgad.1622708&volume=22&pages=50-65&publication_year=2008&author=Mullen%2CTE&author=Marzluff%2CWF have monthly?
- Get to know https://doi.org/10.1038%2Fnsmb972's earnings
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Regulated%20degradation%20of%20replication-dependent%20histone%20mRNAs%20requires%20both%20ATR%20and%20Upf1&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb972&volume=12&pages=794-800&publication_year=2005&author=Kaygun%2CH&author=Marzluff%2CWF generate?
- https://doi.org/10.1261%2Frna.2252511's total income per month
- Find out how much http://scholar.google.com/scholar_lookup?&title=The%20human%20cytoplasmic%20RNA%20terminal%20U-transferase%20ZCCHC11%20targets%20histone%20mRNAs%20for%20degradation&journal=RNA&doi=10.1261%2Frna.2252511&volume=17&pages=39-44&publication_year=2011&author=Schmidt%2CMJ&author=West%2CS&author=Norbury%2CCJ earns monthly
- How much does https://doi.org/10.1021%2Fbi901767w net monthly?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Engineered%20rings%20of%20mixed%20yeast%20Lsm%20proteins%20show%20differential%20interactions%20with%20translation%20factors%20and%20U-rich%20RNA&journal=Biochemistry&doi=10.1021%2Fbi901767w&volume=49&pages=2335-2345&publication_year=2010&author=Sobti%2CM&author=Cubeddu%2CL&author=Haynes%2CPA&author=Mabbutt%2CBC
- What's the monthly money flow for https://doi.org/10.1128%2FMCB.13.2.984?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Histone%20H2A.X%20gene%20transcription%20is%20regulated%20differently%20than%20transcription%20of%20other%20replication-linked%20histone%20genes&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.13.2.984&volume=13&pages=984-992&publication_year=1993&author=Bonner%2CWM&author=Mannironi%2CC&author=Orr%2CA&author=Pilch%2CDR&author=Hatch%2CCL
- Check the income stats for https://doi.org/10.1093%2Fnar%2F17.22.9113
- Get to know http://scholar.google.com/scholar_lookup?&title=H2A.X.%20a%20histone%20isoprotein%20with%20a%20conserved%20C-terminal%20sequence%2C%20is%20encoded%20by%20a%20novel%20mRNA%20with%20both%20DNA%20replication%20type%20and%20polyA%203%E2%80%B2%20processing%20signals&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F17.22.9113&volume=17&pages=9113-9126&publication_year=1989&author=Mannironi%2CC&author=Bonner%2CWM&author=Hatch%2CCL's earnings
- How much cash flow does https://doi.org/10.1038%2Femboj.2011.117 have monthly?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Lsm1%20promotes%20genomic%20stability%20by%20controlling%20histone%20mRNA%20decay&journal=EMBO%20J.&doi=10.1038%2Femboj.2011.117&volume=30&pages=2008-2018&publication_year=2011&author=Herrero%2CAB&author=Moreno%2CS?
- What's the monthly income of https://doi.org/10.1038%2Fni.1902?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Roquin%20binds%20inducible%20costimulator%20mRNA%20and%20effectors%20of%20mRNA%20decay%20to%20induce%20microRNA-independent%20post-transcriptional%20repression&journal=Nat.%20Immunol.&doi=10.1038%2Fni.1902&volume=11&pages=725-733&publication_year=2010&author=Glasmacher%2CE
- How much does https://doi.org/10.1038%2F35006676 gross monthly?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Yeast%20Sm-like%20proteins%20function%20in%20mRNA%20decapping%20and%20decay&journal=Nature&doi=10.1038%2F35006676&volume=404&pages=515-518&publication_year=2000&author=Tharun%2CS?
- What's the total monthly financial gain of https://doi.org/10.1261%2Frna.765807?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=3%E2%80%B2%20Terminal%20oligo%20U-tract-mediated%20stimulation%20of%20decapping&journal=RNA&doi=10.1261%2Frna.765807&volume=13&pages=2356-2365&publication_year=2007&author=Song%2CMG&author=Kiledjian%2CM each month?
- What's the financial outcome of https://doi.org/10.1016%2Fj.cell.2005.07.012?
- What's http://scholar.google.com/scholar_lookup?&title=General%20translational%20repression%20by%20activators%20of%20mRNA%20decapping&journal=Cell&doi=10.1016%2Fj.cell.2005.07.012&volume=122&pages=875-886&publication_year=2005&author=Coller%2CJ&author=Parker%2CR's gross income?
- https://doi.org/10.1093%2Foxfordjournals.jbchem.a122597's financial summary
- How much profit does http://scholar.google.com/scholar_lookup?&title=Uridylation%20of%20U6%20RNA%20in%20a%20nuclear%20extract%20in%20Ehrlich%20ascites%20tumor%20cells&journal=J.%20Biochem.&doi=10.1093%2Foxfordjournals.jbchem.a122597&volume=104&pages=991-994&publication_year=1988&author=Hirai%2CH&author=Lee%2CDI&author=Natori%2CS&author=Sekimizu%2CK generate?
- Find out how much https://doi.org/10.1016%2Fj.molcel.2008.09.014 earns monthly
- How much does http://scholar.google.com/scholar_lookup?&title=Lin28%20mediates%20the%20terminal%20uridylation%20of%20let-7%20precursor%20MicroRNA&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2008.09.014&volume=32&pages=276-284&publication_year=2008&author=Heo%2CI rake in every month?
- How much money does https://doi.org/10.1038%2Fncb1931 make?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Zcchc11-dependent%20uridylation%20of%20microRNA%20directs%20cytokine%20expression&journal=Nat.%20Cell%20Biol.&doi=10.1038%2Fncb1931&volume=11&pages=1157-1163&publication_year=2009&author=Jones%2CMR?
- How much does https://doi.org/10.1016%2Fj.cell.2009.08.002 pull in?
- How much does http://scholar.google.com/scholar_lookup?&title=TUT4%20in%20concert%20with%20Lin28%20suppresses%20microRNA%20biogenesis%20through%20pre-microRNA%20uridylation&journal=Cell&doi=10.1016%2Fj.cell.2009.08.002&volume=138&pages=696-708&publication_year=2009&author=Heo%2CI make?
- What's the financial intake of https://doi.org/10.1038%2Fni1135?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Deletion%20of%20a%20conserved%20Il4%20silencer%20impairs%20T%20helper%20type%201-mediated%20immunity&journal=Nat.%20Immunol.&doi=10.1038%2Fni1135&volume=5&pages=1251-1259&publication_year=2004&author=Ansel%2CKM?
- https://doi.org/10.1016%2Fj.cell.2008.12.023's financial summary
- How much does http://scholar.google.com/scholar_lookup?&title=Importin%208%20is%20a%20gene%20silencing%20factor%20that%20targets%20argonaute%20proteins%20to%20distinct%20mRNAs&journal=Cell&doi=10.1016%2Fj.cell.2008.12.023&volume=136&pages=496-507&publication_year=2009&author=Weinmann%2CL pull in?
- How much does https://doi.org/10.1242%2Fjcs.00708 pull in monthly?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Complex%20protein-DNA%20dynamics%20at%20the%20latent%20origin%20of%20DNA%20replication%20of%20Epstein-Barr%20virus&journal=J.%20Cell%20Sci.&doi=10.1242%2Fjcs.00708&volume=116&pages=3971-3984&publication_year=2003&author=Ritzi%2CM?
- What's the financial intake of https://doi.org/10.1126%2Fscience.1065062?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=An%20abundant%20class%20of%20tiny%20RNAs%20with%20probable%20regulatory%20roles%20in%20Caenorhabditis%20elegans&journal=Science&doi=10.1126%2Fscience.1065062&volume=294&pages=858-862&publication_year=2001&author=Lau%2CNC&author=Lim%2CLP&author=Weinstein%2CEG&author=Bartel%2CDP?
- How much revenue does https://citation-needed.springer.com/v2/references/10.1038/nsmb.2450?format=refman&flavour=references bring in?
- Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kai%20P%20Hoefig
- What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kai%20P%20Hoefig%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
- Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicola%20Rath
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicola%20Rath%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gitta%20A%20Heinz
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gitta%20A%20Heinz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Christine%20Wolf's revenue stream
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Christine%20Wolf%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jasmin%20Dameris earns monthly
- What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jasmin%20Dameris%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Aloys%20Schepers's gross income?
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Aloys%20Schepers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Elisabeth%20Kremmer?
- What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Elisabeth%20Kremmer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=K%20Mark%20Ansel produce monthly?
- Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22K%20Mark%20Ansel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Vigo%20Heissmeyer earns monthly
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Vigo%20Heissmeyer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
- See how much https://static-content.springer.com/esm/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_BFnsmb2450_MOESM7_ESM.pdf makes per month
- Find out how much https://s100.copyright.com/AppDispatchServlet?title=Eri1%20degrades%20the%20stem-loop%20of%20oligouridylated%20histone%20mRNAs%20to%20induce%20replication-dependent%20decay&author=Kai%20P%20Hoefig%20et%20al&contentID=10.1038%2Fnsmb.2450©right=Springer%20Nature%20America%2C%20Inc.&publication=1545-9993&publicationDate=2012-12-02&publisherName=SpringerNature&orderBeanReset=true earns monthly
- How much profit does https://citation-needed.springer.com/v2/references/10.1038/nsmb.2450?format=refman&flavour=citation make?
- How much cash flow does https://doi.org/10.1038/s41594-019-0234-x have monthly?
- Learn how profitable https://doi.org/10.1038/s41467-017-02582-1 is on a monthly basis
- https://doi.org/10.1007/s11427-015-4954-9's revenue stream
- How much money does https://doi.org/10.1038/nrm3645 make?
- What's the total monthly financial gain of https://www.protocols.io/?
- What are the earnings of https://www.natureindex.com/?
- How profitable is http://www.naturechina.com?
- How much does https://www.natureasia.com/ja-jp bring in each month?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref