
NATURE . COM {
}
Title:
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay | Nature Structural & Molecular Biology
Description:
The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1–7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3′ end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3′ end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1–7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3′ oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Education
- Science
- Telecommunications
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.
Keywords {🔍}
article, google, scholar, cas, histone, nature, mrna, cell, mrnas, biol, mol, rna, eri, access, stemloop, nat, marzluff, end, content, molecular, biology, cookies, data, decay, mouse, degradation, struct, decapping, research, privacy, processing, structural, rath, stem, conserved, yeast, uridylation, institute, function, information, replicationdependent, nicola, heinz, ansel, heissmeyer, cells, open, gene, microrna, exonuclease,
Topics {✒️}
nature portfolio permissions reprints privacy policy mouse lymphocyte development german research foundation advertising cancer research social media nature 427 nature 404 nature double-stranded stem-loop structure eri1-deficient mouse cells induce replication-dependent decay conserved c-terminal sequence heterochromatin-dependent gene silencing complex protein-dna dynamics flag-ha-heri1 construct author correspondence replication-linked histone genes stem-loop binding protein springerlink instant access u-rich rna vigo heissmeyer mammalian histone pre-mrna zcchc11-dependent uridylation targets argonaute proteins permissions farm animal biology double-stranded stem gene silencing factor personal data general translational repression roquin promotes recognition stem-loop structure privacy conserved dual role oligouridylated histone mrnas dna replication type elisabeth kremmer lsm1–7 heteroheptamer recognizes probable regulatory roles present address competing financial interests mature histone mrnas cytoplasmic rna data protection data demonstrate histone mrna stability mouse eri1 interacts
Schema {🗺️}
WebPage:
mainEntity:
headline:Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay
description:The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1â7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3â² end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3â² end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1â7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3â² oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
datePublished:2012-12-02T00:00:00Z
dateModified:2012-12-02T00:00:00Z
pageStart:73
pageEnd:81
sameAs:https://doi.org/10.1038/nsmb.2450
keywords:
RNA decay
Structural biology
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig7_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
type:Person
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
type:Person
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay
description:The exoribonuclease Eri1 binds the stem-loop of histone mRNAs, but the functional significance of this interaction has been unclear. New studies now indicate that 3A oligouridylation of histone mRNAs enables the Lsm1â7 complex to bind the oligo(U) tail and to interact with Eri1, whose catalytic activity degrades the double-stranded stem-loop structure. The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3â² end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3â² end but stalls close to the double-stranded stem. Upon oligouridylation of the histone mRNA, the Lsm1â7 heteroheptamer recognizes the oligo(U) tail and interacts with Eri1, whose catalytic activity is then able to degrade the stem-loop in a stepwise manner. These data demonstrate how degradation of histone mRNAs is initiated when 3â² oligouridylation creates a cis element that enables Eri1 to process the double-stranded stem-loop structure.
datePublished:2012-12-02T00:00:00Z
dateModified:2012-12-02T00:00:00Z
pageStart:73
pageEnd:81
sameAs:https://doi.org/10.1038/nsmb.2450
keywords:
RNA decay
Structural biology
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_Article_BFnsmb2450_Fig7_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
type:Person
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
type:Person
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
type:Person
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:20
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Kai P Hoefig
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Nicola Rath
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.
address:
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
type:PostalAddress
type:Organization
name:Gitta A Heinz
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Christine Wolf
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Jasmin Dameris
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Aloys Schepers
affiliation:
name:Research Unit Gene Vectors, Helmholtz Zentrum München
address:
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:Elisabeth Kremmer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
name:K Mark Ansel
affiliation:
name:University of California San Francisco
address:
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
type:PostalAddress
type:Organization
name:Vigo Heissmeyer
affiliation:
name:Institute of Molecular Immunology, Helmholtz Zentrum München
address:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Present address: Beatson Institute for Cancer Research, Glasgow, UK.,
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Research Unit Gene Vectors, Helmholtz Zentrum München, München, Germany
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
name:Department of Microbiology and Immunology, University of California San Francisco, San Francisco, USA
name:Institute of Molecular Immunology, Helmholtz Zentrum München, München, Germany
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(107)
- https://link.springer.com/article/10.1038/nsmb.2450?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle's revenue stream
- Learn about the earnings of https://doi.org/10.1038%2Fnature02302
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=A%20conserved%20siRNA-degrading%20RNase%20negatively%20regulates%20RNA%20interference%20in%20C.%20elegans&journal=Nature&doi=10.1038%2Fnature02302&volume=427&pages=645-649&publication_year=2004&author=Kennedy%2CS&author=Wang%2CD&author=Ruvkun%2CG
- What's the income generated by https://doi.org/10.1016%2Fj.cub.2006.05.061 each month?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Conserved%20ribonuclease%2C%20Eri1%2C%20negatively%20regulates%20heterochromatin%20assembly%20in%20fission%20yeast&journal=Curr.%20Biol.&doi=10.1016%2Fj.cub.2006.05.061&volume=16&pages=1459-1464&publication_year=2006&author=Iida%2CT&author=Kawaguchi%2CR&author=Nakayama%2CJ
- What are the total earnings of https://doi.org/10.1016%2Fj.cell.2006.04.025?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Tethering%20RITS%20to%20a%20nascent%20transcript%20initiates%20RNAi-%20and%20heterochromatin-dependent%20gene%20silencing&journal=Cell&doi=10.1016%2Fj.cell.2006.04.025&volume=125&pages=873-886&publication_year=2006&author=B%C3%BChler%2CM&author=Verdel%2CA&author=Moazed%2CD
- What are the earnings of https://doi.org/10.1182%2Fblood-2011-11-394072?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Eri1%20regulates%20microRNA%20homeostasis%20and%20mouse%20lymphocyte%20development%20and%20antiviral%20function&journal=Blood&doi=10.1182%2Fblood-2011-11-394072&volume=120&pages=130-142&publication_year=2012&author=Thomas%2CMF generate?
- How much does https://doi.org/10.1038%2Fnsmb.1411 gross monthly?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=The%20exonuclease%20ERI-1%20has%20a%20conserved%20dual%20role%20in%205.8S%20rRNA%20processing%20and%20RNAi&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1411&volume=15&pages=531-533&publication_year=2008&author=Gabel%2CHW&author=Ruvkun%2CG
- What's the financial gain of https://doi.org/10.1038%2Fnsmb.1417?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Mouse%20Eri1%20interacts%20with%20the%20ribosome%20and%20catalyzes%205.8S%20rRNA%20processing&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1417&volume=15&pages=523-530&publication_year=2008&author=Ansel%2CKM?
- Discover the revenue of https://doi.org/10.1016%2FS1097-2765%2803%2900278-8
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=A%203%E2%80%B2%20exonuclease%20that%20specifically%20interacts%20with%20the%203%E2%80%B2%20end%20of%20histone%20mRNA&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2803%2900278-8&volume=12&pages=295-305&publication_year=2003&author=Dominski%2CZ&author=Yang%2CXC&author=Kaygun%2CH&author=Dadlez%2CM&author=Marzluff%2CWF
- How much income is https://doi.org/10.1074%2Fjbc.M602947200 earning monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Characterization%20of%203%E2%80%B2hExo%2C%20a%203%E2%80%B2%20exonuclease%20specifically%20interacting%20with%20the%203%E2%80%B2%20end%20of%20histone%20mRNA&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M602947200&volume=281&pages=30447-30454&publication_year=2006&author=Yang%2CXC&author=Purdy%2CM&author=Marzluff%2CWF&author=Dominski%2CZ make?
- What's the monthly income of https://doi.org/10.1017%2FS1355838201001820?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=The%20stem-loop%20binding%20protein%20forms%20a%20highly%20stable%20and%20specific%20complex%20with%20the%203%E2%80%B2%20stem-loop%20of%20histone%20mRNAs&journal=RNA&doi=10.1017%2FS1355838201001820&volume=7&pages=123-132&publication_year=2001&author=Battle%2CDJ&author=Doudna%2CJA is on a monthly basis
- How much does https://doi.org/10.1093%2Fnar%2F28.7.1594 bring in each month?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Positive%20and%20negative%20mutant%20selection%20in%20the%20human%20histone%20hairpin-binding%20protein%20using%20the%20yeast%20three-hybrid%20system&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F28.7.1594&volume=28&pages=1594-1603&publication_year=2000&author=Martin%2CF&author=Michel%2CF&author=Zenklusen%2CD&author=Muller%2CB&author=Schumperli%2CD?
- How much does https://doi.org/10.1093%2Fnar%2F23.4.654 bring in each month?
- How profitable is http://scholar.google.com/scholar_lookup?&title=The%20sequence%20of%20the%20stem%20and%20flanking%20sequences%20at%20the%203%E2%80%B2%20end%20of%20histone%20mRNA%20are%20critical%20determinants%20for%20the%20binding%20of%20the%20stem-loop%20binding%20protein&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F23.4.654&volume=23&pages=654-662&publication_year=1995&author=Williams%2CAS&author=Marzluff%2CWF?
- How much does https://doi.org/10.1128%2FMCB.00296-09 gross monthly?
- How much money does http://scholar.google.com/scholar_lookup?&title=Three%20proteins%20of%20the%20U7-specific%20Sm%20ring%20function%20as%20the%20molecular%20ruler%20to%20determine%20the%20site%20of%203%E2%80%B2-end%20processing%20in%20mammalian%20histone%20pre-mRNA&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.00296-09&volume=29&pages=4045-4056&publication_year=2009&author=Yang%2CXC&author=Torres%2CMP&author=Marzluff%2CWF&author=Dominski%2CZ generate?
- How much does https://doi.org/10.1006%2Fgeno.2002.6850 pull in?
- How much profit does http://scholar.google.com/scholar_lookup?&title=The%20human%20and%20mouse%20replication-dependent%20histone%20genes&journal=Genomics&doi=10.1006%2Fgeno.2002.6850&volume=80&pages=487-498&publication_year=2002&author=Marzluff%2CWF&author=Gongidi%2CP&author=Woods%2CKR&author=Jin%2CJ&author=Maltais%2CLJ make?
- How much does https://doi.org/10.1016%2F0092-8674%2886%2990483-6 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=Normal%20stoichiometry%20of%20histone%20dimer%20sets%20is%20necessary%20for%20high%20fidelity%20of%20mitotic%20chromosome%20transmission&journal=Cell&doi=10.1016%2F0092-8674%2886%2990483-6&volume=44&pages=43-52&publication_year=1986&author=Meeks-Wagner%2CD&author=Hartwell%2CLH pull in?
- What's the income generated by https://doi.org/10.1016%2F0092-8674%2887%2990240-6 each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Translation%20is%20required%20for%20regulation%20of%20histone%20mRNA%20degradation&journal=Cell&doi=10.1016%2F0092-8674%2887%2990240-6&volume=48&pages=615-626&publication_year=1987&author=Graves%2CRA&author=Pandey%2CNB&author=Chodchoy%2CN&author=Marzluff%2CWF earn?
- Get to know what's the income of https://doi.org/10.1128%2FMCB.7.12.4557
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20stem-loop%20structure%20at%20the%203%E2%80%B2%20end%20of%20histone%20mRNA%20is%20necessary%20and%20sufficient%20for%20regulation%20of%20histone%20mRNA%20stability&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.7.12.4557&volume=7&pages=4557-4559&publication_year=1987&author=Pandey%2CNB&author=Marzluff%2CWF produce monthly?
- Learn how profitable https://doi.org/10.1038%2Fnsmb724 is on a monthly basis
- What's the profit of http://scholar.google.com/scholar_lookup?&title=The%20enzymes%20and%20control%20of%20eukaryotic%20mRNA%20turnover&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb724&volume=11&pages=121-127&publication_year=2004&author=Parker%2CR&author=Song%2CH?
- Revenue of https://doi.org/10.1016%2FS1097-2765%2801%2900395-1
- Earnings of http://scholar.google.com/scholar_lookup?&title=Targeting%20an%20mRNA%20for%20decapping%3A%20displacement%20of%20translation%20factors%20and%20association%20of%20the%20Lsm1p-7p%20complex%20on%20deadenylated%20yeast%20mRNAs&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2801%2900395-1&volume=8&pages=1075-1083&publication_year=2001&author=Tharun%2CS&author=Parker%2CR
- How much does https://doi.org/10.1016%2FS0092-8674%2801%2900592-X generate monthly?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Functional%20link%20between%20the%20mammalian%20exosome%20and%20mRNA%20decapping&journal=Cell&doi=10.1016%2FS0092-8674%2801%2900592-X&volume=107&pages=751-762&publication_year=2001&author=Wang%2CZ&author=Kiledjian%2CM
- What's the income generated by https://doi.org/10.1101%2Fgad.1622708 each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20histone%20mRNA%20requires%20oligouridylation%20followed%20by%20decapping%20and%20simultaneous%20degradation%20of%20the%20mRNA%20both%205%E2%80%B2%20to%203%E2%80%B2%20and%203%E2%80%B2%20to%205%E2%80%B2&journal=Genes%20Dev.&doi=10.1101%2Fgad.1622708&volume=22&pages=50-65&publication_year=2008&author=Mullen%2CTE&author=Marzluff%2CWF make?
- What's the financial outcome of https://doi.org/10.1038%2Fnsmb972?
- How much does http://scholar.google.com/scholar_lookup?&title=Regulated%20degradation%20of%20replication-dependent%20histone%20mRNAs%20requires%20both%20ATR%20and%20Upf1&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb972&volume=12&pages=794-800&publication_year=2005&author=Kaygun%2CH&author=Marzluff%2CWF make?
- How much does https://doi.org/10.1261%2Frna.2252511 earn?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20human%20cytoplasmic%20RNA%20terminal%20U-transferase%20ZCCHC11%20targets%20histone%20mRNAs%20for%20degradation&journal=RNA&doi=10.1261%2Frna.2252511&volume=17&pages=39-44&publication_year=2011&author=Schmidt%2CMJ&author=West%2CS&author=Norbury%2CCJ generate?
- What's https://doi.org/10.1021%2Fbi901767w's gross income?
- http://scholar.google.com/scholar_lookup?&title=Engineered%20rings%20of%20mixed%20yeast%20Lsm%20proteins%20show%20differential%20interactions%20with%20translation%20factors%20and%20U-rich%20RNA&journal=Biochemistry&doi=10.1021%2Fbi901767w&volume=49&pages=2335-2345&publication_year=2010&author=Sobti%2CM&author=Cubeddu%2CL&author=Haynes%2CPA&author=Mabbutt%2CBC income
- How much does https://doi.org/10.1128%2FMCB.13.2.984 gross monthly?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Histone%20H2A.X%20gene%20transcription%20is%20regulated%20differently%20than%20transcription%20of%20other%20replication-linked%20histone%20genes&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.13.2.984&volume=13&pages=984-992&publication_year=1993&author=Bonner%2CWM&author=Mannironi%2CC&author=Orr%2CA&author=Pilch%2CDR&author=Hatch%2CCL
- How much does https://doi.org/10.1093%2Fnar%2F17.22.9113 net monthly?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=H2A.X.%20a%20histone%20isoprotein%20with%20a%20conserved%20C-terminal%20sequence%2C%20is%20encoded%20by%20a%20novel%20mRNA%20with%20both%20DNA%20replication%20type%20and%20polyA%203%E2%80%B2%20processing%20signals&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F17.22.9113&volume=17&pages=9113-9126&publication_year=1989&author=Mannironi%2CC&author=Bonner%2CWM&author=Hatch%2CCL
- https://doi.org/10.1038%2Femboj.2011.117 income
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Lsm1%20promotes%20genomic%20stability%20by%20controlling%20histone%20mRNA%20decay&journal=EMBO%20J.&doi=10.1038%2Femboj.2011.117&volume=30&pages=2008-2018&publication_year=2011&author=Herrero%2CAB&author=Moreno%2CS?
- See how much https://doi.org/10.1038%2Fni.1902 makes per month
- How profitable is http://scholar.google.com/scholar_lookup?&title=Roquin%20binds%20inducible%20costimulator%20mRNA%20and%20effectors%20of%20mRNA%20decay%20to%20induce%20microRNA-independent%20post-transcriptional%20repression&journal=Nat.%20Immunol.&doi=10.1038%2Fni.1902&volume=11&pages=725-733&publication_year=2010&author=Glasmacher%2CE?
- Earnings of https://doi.org/10.1038%2F35006676
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Yeast%20Sm-like%20proteins%20function%20in%20mRNA%20decapping%20and%20decay&journal=Nature&doi=10.1038%2F35006676&volume=404&pages=515-518&publication_year=2000&author=Tharun%2CS
- How much profit does https://doi.org/10.1261%2Frna.765807 make?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=3%E2%80%B2%20Terminal%20oligo%20U-tract-mediated%20stimulation%20of%20decapping&journal=RNA&doi=10.1261%2Frna.765807&volume=13&pages=2356-2365&publication_year=2007&author=Song%2CMG&author=Kiledjian%2CM?
- Financial intake of https://doi.org/10.1016%2Fj.cell.2005.07.012
- How much money does http://scholar.google.com/scholar_lookup?&title=General%20translational%20repression%20by%20activators%20of%20mRNA%20decapping&journal=Cell&doi=10.1016%2Fj.cell.2005.07.012&volume=122&pages=875-886&publication_year=2005&author=Coller%2CJ&author=Parker%2CR generate?
- How much does https://doi.org/10.1093%2Foxfordjournals.jbchem.a122597 make?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Uridylation%20of%20U6%20RNA%20in%20a%20nuclear%20extract%20in%20Ehrlich%20ascites%20tumor%20cells&journal=J.%20Biochem.&doi=10.1093%2Foxfordjournals.jbchem.a122597&volume=104&pages=991-994&publication_year=1988&author=Hirai%2CH&author=Lee%2CDI&author=Natori%2CS&author=Sekimizu%2CK have monthly?
- How profitable is https://doi.org/10.1016%2Fj.molcel.2008.09.014?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Lin28%20mediates%20the%20terminal%20uridylation%20of%20let-7%20precursor%20MicroRNA&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2008.09.014&volume=32&pages=276-284&publication_year=2008&author=Heo%2CI
- What are the earnings of https://doi.org/10.1038%2Fncb1931?
- http://scholar.google.com/scholar_lookup?&title=Zcchc11-dependent%20uridylation%20of%20microRNA%20directs%20cytokine%20expression&journal=Nat.%20Cell%20Biol.&doi=10.1038%2Fncb1931&volume=11&pages=1157-1163&publication_year=2009&author=Jones%2CMR income
- What's the total monthly financial gain of https://doi.org/10.1016%2Fj.cell.2009.08.002?
- How much profit does http://scholar.google.com/scholar_lookup?&title=TUT4%20in%20concert%20with%20Lin28%20suppresses%20microRNA%20biogenesis%20through%20pre-microRNA%20uridylation&journal=Cell&doi=10.1016%2Fj.cell.2009.08.002&volume=138&pages=696-708&publication_year=2009&author=Heo%2CI make?
- What's the monthly money flow for https://doi.org/10.1038%2Fni1135?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Deletion%20of%20a%20conserved%20Il4%20silencer%20impairs%20T%20helper%20type%201-mediated%20immunity&journal=Nat.%20Immunol.&doi=10.1038%2Fni1135&volume=5&pages=1251-1259&publication_year=2004&author=Ansel%2CKM earns monthly
- What's the monthly income of https://doi.org/10.1016%2Fj.cell.2008.12.023?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Importin%208%20is%20a%20gene%20silencing%20factor%20that%20targets%20argonaute%20proteins%20to%20distinct%20mRNAs&journal=Cell&doi=10.1016%2Fj.cell.2008.12.023&volume=136&pages=496-507&publication_year=2009&author=Weinmann%2CL produce monthly?
- How much does https://doi.org/10.1242%2Fjcs.00708 bring in each month?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Complex%20protein-DNA%20dynamics%20at%20the%20latent%20origin%20of%20DNA%20replication%20of%20Epstein-Barr%20virus&journal=J.%20Cell%20Sci.&doi=10.1242%2Fjcs.00708&volume=116&pages=3971-3984&publication_year=2003&author=Ritzi%2CM
- How much cash flow does https://doi.org/10.1126%2Fscience.1065062 have monthly?
- What's the income of http://scholar.google.com/scholar_lookup?&title=An%20abundant%20class%20of%20tiny%20RNAs%20with%20probable%20regulatory%20roles%20in%20Caenorhabditis%20elegans&journal=Science&doi=10.1126%2Fscience.1065062&volume=294&pages=858-862&publication_year=2001&author=Lau%2CNC&author=Lim%2CLP&author=Weinstein%2CEG&author=Bartel%2CDP?
- What's the income generated by https://citation-needed.springer.com/v2/references/10.1038/nsmb.2450?format=refman&flavour=references each month?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kai%20P%20Hoefig make?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kai%20P%20Hoefig%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
- Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicola%20Rath
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicola%20Rath%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gitta%20A%20Heinz?
- Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gitta%20A%20Heinz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Christine%20Wolf
- What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Christine%20Wolf%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jasmin%20Dameris earning monthly?
- Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jasmin%20Dameris%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
- What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Aloys%20Schepers?
- What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Aloys%20Schepers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Elisabeth%20Kremmer each month?
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Elisabeth%20Kremmer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=K%20Mark%20Ansel
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22K%20Mark%20Ansel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Vigo%20Heissmeyer making per month?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Vigo%20Heissmeyer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- How profitable is https://static-content.springer.com/esm/art%3A10.1038%2Fnsmb.2450/MediaObjects/41594_2013_BFnsmb2450_MOESM7_ESM.pdf?
- Monthly income for https://s100.copyright.com/AppDispatchServlet?title=Eri1%20degrades%20the%20stem-loop%20of%20oligouridylated%20histone%20mRNAs%20to%20induce%20replication-dependent%20decay&author=Kai%20P%20Hoefig%20et%20al&contentID=10.1038%2Fnsmb.2450©right=Springer%20Nature%20America%2C%20Inc.&publication=1545-9993&publicationDate=2012-12-02&publisherName=SpringerNature&orderBeanReset=true
- How much profit is https://citation-needed.springer.com/v2/references/10.1038/nsmb.2450?format=refman&flavour=citation making per month?
- What are the earnings of https://doi.org/10.1038/s41594-019-0234-x?
- Discover the revenue of https://doi.org/10.1038/s41467-017-02582-1
- How much revenue does https://doi.org/10.1007/s11427-015-4954-9 produce monthly?
- Get to know https://doi.org/10.1038/nrm3645's earnings
- Learn how profitable https://www.protocols.io/ is on a monthly basis
- What are the earnings of https://www.natureindex.com/?
- Revenue of http://www.naturechina.com
- How profitable is https://www.natureasia.com/ja-jp?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref