
NATURE . COM {
}
Title:
An alternative mode of microRNA target recognition | Nature Structural & Molecular Biology
Description:
MicroRNAs are thought to repress mRNA targets through perfect pairing with their seed region, but a sizeable number of miRNA interaction sites are orphans, without a perfect canonical miRNA partner. Now a large number of miRNAs are found to use an alternative binding mode that involves the bulging out of an unpaired mRNA nucleotide, leading to a functional mRNA-miRNA interaction. MicroRNAs (miRNAs) regulate mRNA targets through perfect pairing with their seed region (positions 2–7). Recently, a precise genome-wide map of miRNA interaction sites in mouse brain was generated by high-throughput sequencing and analysis of clusters of ~50-nucleotide mRNA tags cross-linked to Argonaute (Ago HITS-CLIP). By analyzing Ago HITS-CLIP
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Education
- Science
- Animals & Wildlife
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.
Keywords {🔍}
article, cas, google, scholar, nature, cell, microrna, rna, mol, micrornas, access, chi, nat, target, sites, biol, content, wook, darnell, argonaute, cookies, molecular, recognition, sung, hannon, mirnas, brain, hitsclip, struct, silencing, privacy, data, structural, biology, targets, pairing, seed, ago, binding, open, regulation, genes, health, institute, research, supplementary, information, alternative, mouse, interactions,
Topics {✒️}
nature portfolio permissions reprints privacy policy inosine editing author information authors research advertising social media ago clip-based imputation sung wook chi development precise genome-wide map piwi/mid domain protein microrna targeting specificity ago hits-clip facilitate age-specific functions nature 431 nature 433 nature 455 nature 456 nature 460 nature 466 nature 461 nature ago-mirna interactions regulate mrna targets seed-target recognition step springerlink instant access mirna interaction sites permissions risc slicer activity cold spring harbor personal data samsung advanced institute mirna-target interactions mir-302/367 microrna cluster samsung medical center genome-wide identification article chi data protection ago silencing complexes microrna target recognition privacy mice lacking mirna-1–2 microrna targeting code g-bulge sites competing financial interests microrna target sites microrna/target duplexes ago2 binding sites
Schema {🗺️}
WebPage:
mainEntity:
headline:An alternative mode of microRNA target recognition
description:MicroRNAs are thought to repress mRNA targets through perfect pairing with their seed region, but a sizeable number of miRNA interaction sites are orphans, without a perfect canonical miRNA partner. Now a large number of miRNAs are found to use an alternative binding mode that involves the bulging out of an unpaired mRNA nucleotide, leading to a functional mRNA-miRNA interaction. MicroRNAs (miRNAs) regulate mRNA targets through perfect pairing with their seed region (positions 2â7). Recently, a precise genome-wide map of miRNA interaction sites in mouse brain was generated by high-throughput sequencing and analysis of clusters of ~50-nucleotide mRNA tags cross-linked to Argonaute (Ago HITS-CLIP). By analyzing Ago HITS-CLIP 'orphan clusters'âAgo binding regions from HITS-CLIP that cannot be explained by canonical seed matchesâwe have now identified an alternative binding mode used by miRNAs. Specifically, G-bulge sites (positions 5â6) are often bound and regulated by miR-124 in brain. More generally, bulged sites comprise â¥15% of all Ago-miRNA interactions in mouse brain and are evolutionarily conserved. We call position 6 the 'pivot' nucleotide and suggest a model in which a transitional 'nucleation bulge' leads to functional bulge mRNA-miRNA interactions, expanding the number of potential miRNA regulatory sites.
datePublished:2012-02-12T00:00:00Z
dateModified:2012-02-12T00:00:00Z
pageStart:321
pageEnd:327
sameAs:https://doi.org/10.1038/nsmb.2230
keywords:
miRNAs
RNA metabolism
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig5_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:19
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Sung Wook Chi
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University
address:
name:Department of Health Sciences and Technology, Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
type:PostalAddress
type:Organization
name:Samsung Research Institute for Future Medicine, Samsung Medical Center
address:
name:Samsung Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Gregory J Hannon
affiliation:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Robert B Darnell
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:An alternative mode of microRNA target recognition
description:MicroRNAs are thought to repress mRNA targets through perfect pairing with their seed region, but a sizeable number of miRNA interaction sites are orphans, without a perfect canonical miRNA partner. Now a large number of miRNAs are found to use an alternative binding mode that involves the bulging out of an unpaired mRNA nucleotide, leading to a functional mRNA-miRNA interaction. MicroRNAs (miRNAs) regulate mRNA targets through perfect pairing with their seed region (positions 2â7). Recently, a precise genome-wide map of miRNA interaction sites in mouse brain was generated by high-throughput sequencing and analysis of clusters of ~50-nucleotide mRNA tags cross-linked to Argonaute (Ago HITS-CLIP). By analyzing Ago HITS-CLIP 'orphan clusters'âAgo binding regions from HITS-CLIP that cannot be explained by canonical seed matchesâwe have now identified an alternative binding mode used by miRNAs. Specifically, G-bulge sites (positions 5â6) are often bound and regulated by miR-124 in brain. More generally, bulged sites comprise â¥15% of all Ago-miRNA interactions in mouse brain and are evolutionarily conserved. We call position 6 the 'pivot' nucleotide and suggest a model in which a transitional 'nucleation bulge' leads to functional bulge mRNA-miRNA interactions, expanding the number of potential miRNA regulatory sites.
datePublished:2012-02-12T00:00:00Z
dateModified:2012-02-12T00:00:00Z
pageStart:321
pageEnd:327
sameAs:https://doi.org/10.1038/nsmb.2230
keywords:
miRNAs
RNA metabolism
Life Sciences
general
Biochemistry
Protein Structure
Membrane Biology
Biological Microscopy
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_Article_BFnsmb2230_Fig5_HTML.jpg
isPartOf:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:19
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Sung Wook Chi
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University
address:
name:Department of Health Sciences and Technology, Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
type:PostalAddress
type:Organization
name:Samsung Research Institute for Future Medicine, Samsung Medical Center
address:
name:Samsung Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Gregory J Hannon
affiliation:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Robert B Darnell
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Structural & Molecular Biology
issn:
1545-9985
1545-9993
volumeNumber:19
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
name:Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University
address:
name:Department of Health Sciences and Technology, Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
type:PostalAddress
name:Samsung Research Institute for Future Medicine, Samsung Medical Center
address:
name:Samsung Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea
type:PostalAddress
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Sung Wook Chi
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University
address:
name:Department of Health Sciences and Technology, Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
type:PostalAddress
type:Organization
name:Samsung Research Institute for Future Medicine, Samsung Medical Center
address:
name:Samsung Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea
type:PostalAddress
type:Organization
email:[email protected]
name:Gregory J Hannon
affiliation:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute
address:
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Robert B Darnell
affiliation:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute
address:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
name:Department of Health Sciences and Technology, Graduate School, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
name:Samsung Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea
name:Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor, USA
name:Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(107)
- Check the income stats for https://link.springer.com/article/10.1038/nsmb.2230?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle
- Get to know https://doi.org/10.1016%2Fj.cell.2009.02.007's earnings
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=The%20centrality%20of%20RNA&journal=Cell&doi=10.1016%2Fj.cell.2009.02.007&volume=136&pages=577-580&publication_year=2009&author=Sharp%2CPA?
- How much does https://doi.org/10.1038%2Fnrg2673 earn?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=RNA%20processing%20and%20its%20regulation%3A%20global%20insights%20into%20biological%20networks&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2673&volume=11&pages=75-87&publication_year=2010&author=Licatalosi%2CDD&author=Darnell%2CRB each month?
- What's the revenue for https://doi.org/10.1038%2Fnature02871?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20functions%20of%20animal%20microRNAs&journal=Nature&doi=10.1038%2Fnature02871&volume=431&pages=350-355&publication_year=2004&author=Ambros%2CV earn?
- How much does https://doi.org/10.1038%2Fnrg1379 bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=MicroRNAs%3A%20small%20RNAs%20with%20a%20big%20role%20in%20gene%20regulation&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg1379&volume=5&pages=522-531&publication_year=2004&author=He%2CL&author=Hannon%2CGJ pull in monthly?
- How much does https://doi.org/10.1016%2Fj.cell.2009.01.002 make?
- How much does http://scholar.google.com/scholar_lookup?&title=MicroRNAs%3A%20target%20recognition%20and%20regulatory%20functions&journal=Cell&doi=10.1016%2Fj.cell.2009.01.002&volume=136&pages=215-233&publication_year=2009&author=Bartel%2CDP pull in?
- What's the financial outcome of https://doi.org/10.1016%2Fj.cell.2004.12.035?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Conserved%20seed%20pairing%2C%20often%20flanked%20by%20adenosines%2C%20indicates%20that%20thousands%20of%20human%20genes%20are%20microRNA%20targets&journal=Cell&doi=10.1016%2Fj.cell.2004.12.035&volume=120&pages=15-20&publication_year=2005&author=Lewis%2CBP&author=Burge%2CCB&author=Bartel%2CDP?
- Get to know https://doi.org/10.1038%2Fnsmb1226's earnings
- Get to know http://scholar.google.com/scholar_lookup?&title=Potent%20effect%20of%20target%20structure%20on%20microRNA%20function&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb1226&volume=14&pages=287-294&publication_year=2007&author=Long%2CD's earnings
- Revenue of https://doi.org/10.1016%2Fj.molcel.2007.06.017
- http://scholar.google.com/scholar_lookup?&title=MicroRNA%20targeting%20specificity%20in%20mammals%3A%20determinants%20beyond%20seed%20pairing&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2007.06.017&volume=27&pages=91-105&publication_year=2007&author=Grimson%2CA income
- How much does https://doi.org/10.1038%2Fnature03315 generate monthly?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Microarray%20analysis%20shows%20that%20some%20microRNAs%20downregulate%20large%20numbers%20of%20target%20mRNAs&journal=Nature&doi=10.1038%2Fnature03315&volume=433&pages=769-773&publication_year=2005&author=Lim%2CLP
- How much does https://doi.org/10.1038%2Fnature07242 generate monthly?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=The%20impact%20of%20microRNAs%20on%20protein%20output&journal=Nature&doi=10.1038%2Fnature07242&volume=455&pages=64-71&publication_year=2008&author=Baek%2CD?
- How much cash flow does https://doi.org/10.1038%2Fnature07228 have monthly?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Widespread%20changes%20in%20protein%20synthesis%20induced%20by%20microRNAs&journal=Nature&doi=10.1038%2Fnature07228&volume=455&pages=58-63&publication_year=2008&author=Selbach%2CM?
- How much does https://doi.org/10.1038%2F455044a pull in?
- http://scholar.google.com/scholar_lookup?&title=Small%20RNAs%3A%20the%20seeds%20of%20silence&journal=Nature&doi=10.1038%2F455044a&volume=455&pages=44-45&publication_year=2008&author=Mourelatos%2CZ's total income per month
- How much cash flow does https://doi.org/10.1261%2Frna.563707 have monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Isolation%20of%20microRNA%20targets%20by%20miRNP%20immunopurification&journal=RNA&doi=10.1261%2Frna.563707&volume=13&pages=1198-1204&publication_year=2007&author=Easow%2CG&author=Teleman%2CAA&author=Cohen%2CSM earn?
- Check the income stats for https://doi.org/10.1101%2Fgad.10.23.3041
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=A%20bulged%20lin-4%2Flin-14%20RNA%20duplex%20is%20sufficient%20for%20Caenorhabditis%20elegans%20lin-14%20temporal%20gradient%20formation&journal=Genes%20Dev.&doi=10.1101%2Fgad.10.23.3041&volume=10&pages=3041-3050&publication_year=1996&author=Ha%2CI&author=Wightman%2CB&author=Ruvkun%2CG?
- How much profit does https://doi.org/10.1101%2Fgad.1165404 generate?
- Income figures for http://scholar.google.com/scholar_lookup?&title=The%20C.%20elegans%20microRNA%20let-7%20binds%20to%20imperfect%20let-7%20complementary%20sites%20from%20the%20lin-41%203%E2%80%B2UTR&journal=Genes%20Dev.&doi=10.1101%2Fgad.1165404&volume=18&pages=132-137&publication_year=2004&author=Vella%2CMC&author=Choi%2CEY&author=Lin%2CSY&author=Reinert%2CK&author=Slack%2CFJ
- How much does https://doi.org/10.1038%2Fnature07299 gross monthly?
- http://scholar.google.com/scholar_lookup?&title=MicroRNAs%20to%20Nanog%2C%20Oct4%20and%20Sox2%20coding%20regions%20modulate%20embryonic%20stem%20cell%20differentiation&journal=Nature&doi=10.1038%2Fnature07299&volume=455&pages=1124-1128&publication_year=2008&author=Tay%2CY&author=Zhang%2CJ&author=Thomson%2CAM&author=Lim%2CB&author=Rigoutsos%2CI income
- How much profit is https://doi.org/10.1038%2Fnsmb1138 making per month?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Perfect%20seed%20pairing%20is%20not%20a%20generally%20reliable%20predictor%20for%20miRNA-target%20interactions&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb1138&volume=13&pages=849-851&publication_year=2006&author=Didiano%2CD&author=Hobert%2CO
- How much does https://doi.org/10.1038%2Fnmeth.1247 pull in monthly?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=mirWIP%3A%20microRNA%20target%20prediction%20based%20on%20microRNA-containing%20ribonucleoprotein-enriched%20transcripts&journal=Nat.%20Methods&doi=10.1038%2Fnmeth.1247&volume=5&pages=813-819&publication_year=2008&author=Hammell%2CM
- Income figures for https://doi.org/10.1073%2Fpnas.0709971104
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=A%20biochemical%20approach%20to%20identifying%20microRNA%20targets&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0709971104&volume=104&pages=19291-19296&publication_year=2007&author=Karginov%2CFV have monthly?
- How much does https://doi.org/10.1126%2Fscience.1090095 pull in?
- What's http://scholar.google.com/scholar_lookup?&title=CLIP%20identifies%20Nova-regulated%20RNA%20networks%20in%20the%20brain&journal=Science&doi=10.1126%2Fscience.1090095&volume=302&pages=1212-1215&publication_year=2003&author=Ule%2CJ's gross income?
- What's the income of https://doi.org/10.1038%2Fnature07488?
- Get to know http://scholar.google.com/scholar_lookup?&title=HITS-CLIP%20yields%20genome-wide%20insights%20into%20brain%20alternative%20RNA%20processing&journal=Nature&doi=10.1038%2Fnature07488&volume=456&pages=464-469&publication_year=2008&author=Licatalosi%2CDD's earnings
- Learn how profitable https://doi.org/10.1002%2Fwrna.31 is on a monthly basis
- What's http://scholar.google.com/scholar_lookup?&title=HITS-CLIP%3A%20panoramic%20views%20of%20protein-RNA%20regulation%20in%20living%20cells&journal=Wiley%20Interdiscip.%20Rev.%20RNA&doi=10.1002%2Fwrna.31&volume=1&pages=266-286&publication_year=2010&author=Darnell%2CRB's gross income?
- What's the income generated by https://doi.org/10.1038%2Fnature08170 each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Argonaute%20HITS-CLIP%20decodes%20microRNA-mRNA%20interaction%20maps&journal=Nature&doi=10.1038%2Fnature08170&volume=460&pages=479-486&publication_year=2009&author=Chi%2CSW&author=Zang%2CJB&author=Mele%2CA&author=Darnell%2CRB make?
- Get to know what's the income of https://doi.org/10.1038%2Fnsmb.1745
- How much does http://scholar.google.com/scholar_lookup?&title=Comprehensive%20discovery%20of%20endogenous%20Argonaute%20binding%20sites%20in%20Caenorhabditis%20elegans&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1745&volume=17&pages=173-179&publication_year=2010&author=Zisoulis%2CDG net monthly?
- How much does https://doi.org/10.1016%2Fj.cell.2010.03.009 pull in?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Transcriptome-wide%20identification%20of%20RNA-binding%20protein%20and%20microRNA%20target%20sites%20by%20PAR-CLIP&journal=Cell&doi=10.1016%2Fj.cell.2010.03.009&volume=141&pages=129-141&publication_year=2010&author=Hafner%2CM?
- Find out how much https://doi.org/10.1038%2Fnsmb.1991 earns monthly
- How much does http://scholar.google.com/scholar_lookup?&title=Genome-wide%20identification%20of%20Ago2%20binding%20sites%20from%20mouse%20embryonic%20stem%20cells%20with%20and%20without%20mature%20microRNAs&journal=Nat.%20Struct.%20Mol.%20Biol.&doi=10.1038%2Fnsmb.1991&volume=18&pages=237-244&publication_year=2011&author=Leung%2CAK net monthly?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Fitting%20a%20mixture%20model%20by%20expectation%20maximization%20to%20discover%20motifs%20in%20biopolymers&journal=Proc.%20Int.%20Conf.%20Intell.%20Syst.%20Mol.%20Biol.&volume=2&pages=28-36&publication_year=1994&author=Bailey%2CTL&author=Elkan%2CC?
- How much does https://doi.org/10.1038%2Fnbt.1543 rake in every month?
- How much money does http://scholar.google.com/scholar_lookup?&title=Transfection%20of%20small%20RNAs%20globally%20perturbs%20gene%20regulation%20by%20endogenous%20microRNAs&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt.1543&volume=27&pages=549-555&publication_year=2009&author=Khan%2CAA make?
- How much does https://doi.org/10.1126%2Fscience.1122689 pull in monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Zebrafish%20MiR-430%20promotes%20deadenylation%20and%20clearance%20of%20maternal%20mRNAs&journal=Science&doi=10.1126%2Fscience.1122689&volume=312&pages=75-79&publication_year=2006&author=Giraldez%2CAJ net monthly?
- Monthly income for https://doi.org/10.1128%2FMCB.02005-06
- Earnings of http://scholar.google.com/scholar_lookup?&title=Transcripts%20targeted%20by%20the%20microRNA-16%20family%20cooperatively%20regulate%20cell%20cycle%20progression&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.02005-06&volume=27&pages=2240-2252&publication_year=2007&author=Linsley%2CPS
- What's the total monthly financial gain of https://doi.org/10.1126%2Fscience.1138050?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Redirection%20of%20silencing%20targets%20by%20adenosine-to-inosine%20editing%20of%20miRNAs&journal=Science&doi=10.1126%2Fscience.1138050&volume=315&pages=1137-1140&publication_year=2007&author=Kawahara%2CY?
- What's the revenue for https://doi.org/10.1016%2Fj.cell.2007.03.030?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Dysregulation%20of%20cardiogenesis%2C%20cardiac%20conduction%2C%20and%20cell%20cycle%20in%20mice%20lacking%20miRNA-1%E2%80%932&journal=Cell&doi=10.1016%2Fj.cell.2007.03.030&volume=129&pages=303-317&publication_year=2007&author=Zhao%2CY bring in?
- How much does https://doi.org/10.1038%2Fnature09191 gross monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Pathogenic%20LRRK2%20negatively%20regulates%20microRNA-mediated%20translational%20repression&journal=Nature&doi=10.1038%2Fnature09191&volume=466&pages=637-641&publication_year=2010&author=Gehrke%2CS&author=Imai%2CY&author=Sokol%2CN&author=Lu%2CB earn?
- How much revenue does https://doi.org/10.1126%2Fscience.1102514 produce monthly?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Crystal%20structure%20of%20Argonaute%20and%20its%20implications%20for%20RISC%20slicer%20activity&journal=Science&doi=10.1126%2Fscience.1102514&volume=305&pages=1434-1437&publication_year=2004&author=Song%2CJJ&author=Smith%2CSK&author=Hannon%2CGJ&author=Joshua-Tor%2CL?
- Earnings of https://doi.org/10.1038%2Fnature07666
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Structure%20of%20an%20argonaute%20silencing%20complex%20with%20a%20seed-containing%20guide%20DNA%20and%20target%20RNA%20duplex&journal=Nature&doi=10.1038%2Fnature07666&volume=456&pages=921-926&publication_year=2008&author=Wang%2CY generate?
- How much profit does https://doi.org/10.1038%2Fnature07315 make?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Structure%20of%20the%20guide-strand-containing%20argonaute%20silencing%20complex&journal=Nature&doi=10.1038%2Fnature07315&volume=456&pages=209-213&publication_year=2008&author=Wang%2CY&author=Sheng%2CG&author=Juranek%2CS&author=Tuschl%2CT&author=Patel%2CDJ?
- What's the revenue for https://doi.org/10.1038%2Fnature08434?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Nucleation%2C%20propagation%20and%20cleavage%20of%20target%20RNAs%20in%20Ago%20silencing%20complexes&journal=Nature&doi=10.1038%2Fnature08434&volume=461&pages=754-761&publication_year=2009&author=Wang%2CY?
- How much profit does https://doi.org/10.1006%2Fjmbi.1999.3001 make?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=How%20RNA%20folds&journal=J.%20Mol.%20Biol.&doi=10.1006%2Fjmbi.1999.3001&volume=293&pages=271-281&publication_year=1999&author=Tinoco%2CI&author=Bustamante%2CC?
- See how much https://doi.org/10.1016%2Fj.molcel.2008.12.012 makes per month
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Enhancement%20of%20the%20seed-target%20recognition%20step%20in%20RNA%20silencing%20by%20a%20PIWI%2FMID%20domain%20protein&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2008.12.012&volume=33&pages=204-214&publication_year=2009&author=Parker%2CJS&author=Parizotto%2CEA&author=Wang%2CM&author=Roe%2CSM&author=Barford%2CD generate?
- Income figures for https://doi.org/10.1016%2Fj.molcel.2009.08.020
- How profitable is http://scholar.google.com/scholar_lookup?&title=miR-24%20Inhibits%20cell%20proliferation%20by%20targeting%20E2F2%2C%20MYC%2C%20and%20other%20cell-cycle%20genes%20via%20binding%20to%20%27seedless%27%203%E2%80%B2UTR%20microRNA%20recognition%20elements&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2009.08.020&volume=35&pages=610-625&publication_year=2009&author=Lal%2CA?
- How much does https://doi.org/10.1016%2Fj.molcel.2010.06.005 net monthly?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Expanding%20the%20microRNA%20targeting%20code%3A%20functional%20sites%20with%20centered%20pairing&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2010.06.005&volume=38&pages=789-802&publication_year=2010&author=Shin%2CC?
- How much revenue does https://doi.org/10.1261%2Frna.5248604 generate?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Fast%20and%20effective%20prediction%20of%20microRNA%2Ftarget%20duplexes&journal=RNA&doi=10.1261%2Frna.5248604&volume=10&pages=1507-1517&publication_year=2004&author=Rehmsmeier%2CM&author=Steffen%2CP&author=Hochsmann%2CM&author=Giegerich%2CR?
- Get to know https://doi.org/10.1261%2Frna.646007's earnings
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=A%20novel%20monoclonal%20antibody%20against%20human%20Argonaute%20proteins%20reveals%20unexpected%20characteristics%20of%20miRNAs%20in%20human%20blood%20cells&journal=RNA&doi=10.1261%2Frna.646007&volume=13&pages=1787-1792&publication_year=2007&author=Nelson%2CPT?
- See how much https://doi.org/10.1016%2FS0092-8674%2801%2900568-2 makes per month
- How much does http://scholar.google.com/scholar_lookup?&title=Microarray%20identification%20of%20FMRP-associated%20brain%20mRNAs%20and%20altered%20mRNA%20translational%20profiles%20in%20fragile%20X%20syndrome&journal=Cell&doi=10.1016%2FS0092-8674%2801%2900568-2&volume=107&pages=477-487&publication_year=2001&author=Brown%2CV pull in?
- What are the earnings of https://citation-needed.springer.com/v2/references/10.1038/nsmb.2230?format=refman&flavour=references?
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sung%20Wook%20Chi
- Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sung%20Wook%20Chi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gregory%20J%20Hannon?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gregory%20J%20Hannon%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Robert%20B%20Darnell generate?
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Robert%20B%20Darnell%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fnsmb.2230/MediaObjects/41594_2012_BFnsmb2230_MOESM8_ESM.pdf rake in every month?
- How much does https://s100.copyright.com/AppDispatchServlet?title=An%20alternative%20mode%20of%20microRNA%20target%20recognition&author=Sung%20Wook%20Chi%20et%20al&contentID=10.1038%2Fnsmb.2230©right=Springer%20Nature%20America%2C%20Inc.&publication=1545-9993&publicationDate=2012-02-12&publisherName=SpringerNature&orderBeanReset=true rake in every month?
- How much profit does https://citation-needed.springer.com/v2/references/10.1038/nsmb.2230?format=refman&flavour=citation make?
- Learn how profitable https://doi.org/10.1038/s41576-023-00611-y is on a monthly basis
- https://doi.org/10.1038/s41598-021-98708-z income
- How much does https://doi.org/10.1007/s11010-020-03889-2 pull in?
- https://doi.org/10.1038/s41594-020-0451-3's total income per month
- How much does https://doi.org/10.1038/s41586-020-2586-0 gross monthly?
- How much does https://www.protocols.io/ rake in every month?
- How much does https://www.natureindex.com/ generate monthly?
- Learn how profitable http://www.naturechina.com is on a monthly basis
- What are the total earnings of https://www.natureasia.com/ja-jp?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref