Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/nrmicro.2017.42.

Title:
Persistent bacterial infections and persister cells | Nature Reviews Microbiology
Description:
Many bacteria can infect and persist inside their hosts for long periods of time. In this Review, Fisher, Gollan and Helaine discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections. Many bacteria can infect and persist inside their hosts for long periods of time. This can be due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective killing by antibiotics. Bacteria can survive antibiotic treatment if they are resistant or tolerant to a drug. Persisters are a subpopulation of transiently antibiotic-tolerant bacterial cells that are often slow-growing or growth-arrested, and are able to resume growth after a lethal stress. The formation of persister cells establishes phenotypic heterogeneity within a bacterial population and has been hypothesized to be important for increasing the chances of successfully adapting to environmental change. The presence of persister cells can result in the recalcitrance and relapse of persistent bacterial infections, and it has been linked to an increase in the risk of the emergence of antibiotic resistance during treatment. If the mechanisms of the formation and regrowth of these antibiotic-tolerant cells were better understood, it could lead to the development of new approaches for the eradication of persistent bacterial infections. In this Review, we discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Business & Finance

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$531,700 per month
Our estimates place Nature.com's monthly online earnings from display ads at $354,480 to $974,820.

Keywords {🔍}

pubmed, google, scholar, cas, central, bacterial, microbiol, antibiotic, persistence, nature, cell, cells, infections, coli, persister, tolerance, escherichia, nat, persisters, formation, toxinantitoxin, rev, mol, host, gerdes, article, persistent, response, infection, protein, resistance, lewis, dna, sci, treatment, bacteria, system, growth, access, proc, natl, acad, usa, helaine, stress, aureus, biol, salmonella, toxin, content,

Topics {✒️}

nature portfolio journals nature portfolio permissions reprints privacy policy advertising broad-host-range plasmid rk2 disrupts toxin–antitoxin–promoter interactions author information authors hokb–sokb toxin–antitoxin system social media agr quorum-sensing system van den bergh bridget gollan & sophie helaine single-gene knockout mutants atp-dependent persister formation hipba–promoter structures reveal author correspondence nature+ nature 513 nature 524 nature 503 nature 473 nature 427 nature 527 nature macrophage-induced efflux mechanism rele–homologous mrna interferases multiple toxin–antitoxin systems microbial bet-hedging strategy mazef toxin–antitoxin module lethal double-stranded breaks stress-response sigma factor engineering persister-specific antibiotics highly efficient antibacterial drug-induced tolerant persisters personal data antibiotic-tolerant persister cells low-copy-number plasmids toxin–antitoxin modules data protection mhc ii molecules springerlink instant access growth-arrested persisters regrow toxin–antitoxin activity toxin–antitoxin loci long-term impacts mhc class ii single metabolic stress toxin–antitoxin systems persister heterogeneity arising

Questions {❓}

  • What role does the quorum-sensing accessory gene regulator system play during Staphylococcus aureus bacteremia?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Persistent bacterial infections and persister cells
         description: Many bacteria can infect and persist inside their hosts for long periods of time. In this Review, Fisher, Gollan and Helaine discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections. Many bacteria can infect and persist inside their hosts for long periods of time. This can be due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective killing by antibiotics. Bacteria can survive antibiotic treatment if they are resistant or tolerant to a drug. Persisters are a subpopulation of transiently antibiotic-tolerant bacterial cells that are often slow-growing or growth-arrested, and are able to resume growth after a lethal stress. The formation of persister cells establishes phenotypic heterogeneity within a bacterial population and has been hypothesized to be important for increasing the chances of successfully adapting to environmental change. The presence of persister cells can result in the recalcitrance and relapse of persistent bacterial infections, and it has been linked to an increase in the risk of the emergence of antibiotic resistance during treatment. If the mechanisms of the formation and regrowth of these antibiotic-tolerant cells were better understood, it could lead to the development of new approaches for the eradication of persistent bacterial infections. In this Review, we discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections.
         datePublished:2017-05-22T00:00:00Z
         dateModified:2017-05-22T00:00:00Z
         pageStart:453
         pageEnd:464
         sameAs:https://doi.org/10.1038/nrmicro.2017.42
         keywords:
            Antibacterial drug resistance
            Antibiotics
            Bacterial evolution
            Bacterial physiology
            Cellular microbiology
            Clinical microbiology
            Infectious diseases
            Life Sciences
            general
            Microbiology
            Medical Microbiology
            Parasitology
            Infectious Diseases
            Virology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig3_HTML.jpg
         isPartOf:
            name:Nature Reviews Microbiology
            issn:
               1740-1534
               1740-1526
            volumeNumber:15
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Robert A. Fisher
               affiliation:
                     name:MRC Centre for Molecular Bacteriology and Infection
                     address:
                        name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bridget Gollan
               affiliation:
                     name:MRC Centre for Molecular Bacteriology and Infection
                     address:
                        name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sophie Helaine
               affiliation:
                     name:MRC Centre for Molecular Bacteriology and Infection
                     address:
                        name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Persistent bacterial infections and persister cells
      description: Many bacteria can infect and persist inside their hosts for long periods of time. In this Review, Fisher, Gollan and Helaine discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections. Many bacteria can infect and persist inside their hosts for long periods of time. This can be due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective killing by antibiotics. Bacteria can survive antibiotic treatment if they are resistant or tolerant to a drug. Persisters are a subpopulation of transiently antibiotic-tolerant bacterial cells that are often slow-growing or growth-arrested, and are able to resume growth after a lethal stress. The formation of persister cells establishes phenotypic heterogeneity within a bacterial population and has been hypothesized to be important for increasing the chances of successfully adapting to environmental change. The presence of persister cells can result in the recalcitrance and relapse of persistent bacterial infections, and it has been linked to an increase in the risk of the emergence of antibiotic resistance during treatment. If the mechanisms of the formation and regrowth of these antibiotic-tolerant cells were better understood, it could lead to the development of new approaches for the eradication of persistent bacterial infections. In this Review, we discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections.
      datePublished:2017-05-22T00:00:00Z
      dateModified:2017-05-22T00:00:00Z
      pageStart:453
      pageEnd:464
      sameAs:https://doi.org/10.1038/nrmicro.2017.42
      keywords:
         Antibacterial drug resistance
         Antibiotics
         Bacterial evolution
         Bacterial physiology
         Cellular microbiology
         Clinical microbiology
         Infectious diseases
         Life Sciences
         general
         Microbiology
         Medical Microbiology
         Parasitology
         Infectious Diseases
         Virology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrmicro.2017.42/MediaObjects/41579_2017_Article_BFnrmicro201742_Fig3_HTML.jpg
      isPartOf:
         name:Nature Reviews Microbiology
         issn:
            1740-1534
            1740-1526
         volumeNumber:15
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Robert A. Fisher
            affiliation:
                  name:MRC Centre for Molecular Bacteriology and Infection
                  address:
                     name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bridget Gollan
            affiliation:
                  name:MRC Centre for Molecular Bacteriology and Infection
                  address:
                     name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sophie Helaine
            affiliation:
                  name:MRC Centre for Molecular Bacteriology and Infection
                  address:
                     name:MRC Centre for Molecular Bacteriology and Infection, London, UK
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Reviews Microbiology
      issn:
         1740-1534
         1740-1526
      volumeNumber:15
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:MRC Centre for Molecular Bacteriology and Infection
      address:
         name:MRC Centre for Molecular Bacteriology and Infection, London, UK
         type:PostalAddress
      name:MRC Centre for Molecular Bacteriology and Infection
      address:
         name:MRC Centre for Molecular Bacteriology and Infection, London, UK
         type:PostalAddress
      name:MRC Centre for Molecular Bacteriology and Infection
      address:
         name:MRC Centre for Molecular Bacteriology and Infection, London, UK
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Robert A. Fisher
      affiliation:
            name:MRC Centre for Molecular Bacteriology and Infection
            address:
               name:MRC Centre for Molecular Bacteriology and Infection, London, UK
               type:PostalAddress
            type:Organization
      name:Bridget Gollan
      affiliation:
            name:MRC Centre for Molecular Bacteriology and Infection
            address:
               name:MRC Centre for Molecular Bacteriology and Infection, London, UK
               type:PostalAddress
            type:Organization
      name:Sophie Helaine
      affiliation:
            name:MRC Centre for Molecular Bacteriology and Infection
            address:
               name:MRC Centre for Molecular Bacteriology and Infection, London, UK
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:MRC Centre for Molecular Bacteriology and Infection, London, UK
      name:MRC Centre for Molecular Bacteriology and Infection, London, UK
      name:MRC Centre for Molecular Bacteriology and Infection, London, UK
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

External Links {🔗}(400)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

6.51s.