NATURE . COM {}

Matching Content Categories {📚}

• Telecommunications
• Education
• Environment

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our analysis indicates Nature.com generates between $42,042 and $115,616 monthly online from display ads.

Keywords {🔍}

article, nature, cas, google, scholar, access, content, neurons, research, cookies, agrp, center, privacy, synaptic, release, gaba, obesity, data, information, energy, tong, lowell, hypothalamic, mice, open, nat, neurosci, medical, boston, supplementary, advertising, subscribe, neuroscience, communications, balance, jones, bradford, generated, institution, buy, cell, neuron, endocrinology, bbl, author, permissions, optional, media, personal, parties,

Topics {✒️}

nature portfolio permissions reprints privacy policy hypothalamic–pituitary–adrenal axis amelia hypothalamic research advertising lowell nature social media nature 411 nature 449 nature author information authors author correspondence npy-mediated synaptic plasticity personal data agrp-ires-cre mice springerlink instant access data protection permissions agrp neuron–specific deletion starvation stephan dodtnoah harvard medical school european economic area privacy communications article regulating energy balance communication published explore content subscription content hypothalamic neurocircuits agouti-related protein attenuated hyperphagic response issue learn institutional subscriptions read brain leptin action north american association electrophysiological recording studies accepting optional cookies journals search log young investigator award vgatflox/flox mice chian-ping ye article tong manage preferences vesicular gaba transporter agrp neurons content arcuate neurons energy balance https

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
         description:Neurons expressing Agouti-related protein (AgRP) and neuropeptide Y (NPY) in the hypothalamus are involved in regulation of feeding and body weight, but genetic disruption of AgRP and NPY have little effect on energy homeostasis. A new study from Tong et al. shows that the energy homeostasis function is mediated through their GABAergic transmission. The physiologic importance of GABAergic neurotransmission in hypothalamic neurocircuits is unknown. To examine the importance of GABA release from agouti-related protein (AgRP) neurons (which also release AgRP and neuropeptide Y), we generated mice with an AgRP neuron–specific deletion of vesicular GABA transporter. These mice are lean, resistant to obesity and have an attenuated hyperphagic response to ghrelin. Thus, GABA release from AgRP neurons is important in regulating energy balance.
         datePublished:2008-08-10T00:00:00Z
         dateModified:2008-08-10T00:00:00Z
         pageStart:998
         pageEnd:1000
         sameAs:https://doi.org/10.1038/nn.2167
         keywords:
            Biomedicine
            general
            Neurosciences
            Behavioral Sciences
            Biological Techniques
            Neurobiology
            Animal Genetics and Genomics
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig3_HTML.jpg
         isPartOf:
            name:Nature Neuroscience
            issn:
               1546-1726
               1097-6256
            volumeNumber:11
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Qingchun Tong
               affiliation:
                     name:Beth Israel Deaconess Medical Center and Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chian-Ping Ye
               affiliation:
                     name:Beth Israel Deaconess Medical Center and Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Juli E Jones
               affiliation:
                     name:Beth Israel Deaconess Medical Center and Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Joel K Elmquist
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bradford B Lowell
               affiliation:
                     name:Beth Israel Deaconess Medical Center and Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
      description:Neurons expressing Agouti-related protein (AgRP) and neuropeptide Y (NPY) in the hypothalamus are involved in regulation of feeding and body weight, but genetic disruption of AgRP and NPY have little effect on energy homeostasis. A new study from Tong et al. shows that the energy homeostasis function is mediated through their GABAergic transmission. The physiologic importance of GABAergic neurotransmission in hypothalamic neurocircuits is unknown. To examine the importance of GABA release from agouti-related protein (AgRP) neurons (which also release AgRP and neuropeptide Y), we generated mice with an AgRP neuron–specific deletion of vesicular GABA transporter. These mice are lean, resistant to obesity and have an attenuated hyperphagic response to ghrelin. Thus, GABA release from AgRP neurons is important in regulating energy balance.
      datePublished:2008-08-10T00:00:00Z
      dateModified:2008-08-10T00:00:00Z
      pageStart:998
      pageEnd:1000
      sameAs:https://doi.org/10.1038/nn.2167
      keywords:
         Biomedicine
         general
         Neurosciences
         Behavioral Sciences
         Biological Techniques
         Neurobiology
         Animal Genetics and Genomics
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_Article_BFnn2167_Fig3_HTML.jpg
      isPartOf:
         name:Nature Neuroscience
         issn:
            1546-1726
            1097-6256
         volumeNumber:11
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Qingchun Tong
            affiliation:
                  name:Beth Israel Deaconess Medical Center and Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chian-Ping Ye
            affiliation:
                  name:Beth Israel Deaconess Medical Center and Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Juli E Jones
            affiliation:
                  name:Beth Israel Deaconess Medical Center and Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Joel K Elmquist
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bradford B Lowell
            affiliation:
                  name:Beth Israel Deaconess Medical Center and Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Neuroscience
      issn:
         1546-1726
         1097-6256
      volumeNumber:11
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Beth Israel Deaconess Medical Center and Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center and Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center and Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center and Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Qingchun Tong
      affiliation:
            name:Beth Israel Deaconess Medical Center and Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Chian-Ping Ye
      affiliation:
            name:Beth Israel Deaconess Medical Center and Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Juli E Jones
      affiliation:
            name:Beth Israel Deaconess Medical Center and Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Joel K Elmquist
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Bradford B Lowell
      affiliation:
            name:Beth Israel Deaconess Medical Center and Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
      name:Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

• https://twitter.com/natureneuro

External Links {🔗}(54)

• How much income does https://link.springer.com/article/10.1038/nn.2167?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle have?
• How much does https://doi.org/10.1096%2Ffj.04-3434fje pull in monthly?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=&journal=FASEB%20J.&doi=10.1096%2Ffj.04-3434fje&volume=19&pages=1680-1682&publication_year=2005&author=Bewick%2CGA?
• Check the income stats for https://doi.org/10.1038%2Fnn1548
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=&journal=Nat.%20Neurosci.&doi=10.1038%2Fnn1548&volume=8&pages=1289-1291&publication_year=2005&author=Gropp%2CE is on a monthly basis
• What's https://doi.org/10.1126%2Fscience.1115524's gross income?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=&journal=Science&doi=10.1126%2Fscience.1115524&volume=310&pages=683-685&publication_year=2005&author=Luquet%2CS&author=Perez%2CFA&author=Hnasko%2CTS&author=Palmiter%2CRD?
• What is the earnings of https://doi.org/10.1128%2FMCB.22.14.5027-5035.2002?
• How much income is http://scholar.google.com/scholar_lookup?&title=&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.22.14.5027-5035.2002&volume=22&pages=5027-5035&publication_year=2002&author=Qian%2CS earning monthly?
• What's the total monthly financial gain of https://doi.org/10.1016%2Fj.cmet.2006.01.003?
• See how much http://scholar.google.com/scholar_lookup?&title=&journal=Cell%20Metab.&doi=10.1016%2Fj.cmet.2006.01.003&volume=3&pages=83-85&publication_year=2006&author=Flier%2CJS makes per month
• How much money does https://doi.org/10.1016%2Fj.neuron.2004.06.004 generate?
• How profitable is http://scholar.google.com/scholar_lookup?&title=&journal=Neuron&doi=10.1016%2Fj.neuron.2004.06.004&volume=42&pages=983-991&publication_year=2004&author=Balthasar%2CN?
• How much money does https://doi.org/10.1038%2F35078085 generate?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=&journal=Nature&doi=10.1038%2F35078085&volume=411&pages=480-484&publication_year=2001&author=Cowley%2CMA?
• How much does https://doi.org/10.1016%2Fj.neuron.2006.04.016 earn?
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=&journal=Neuron&doi=10.1016%2Fj.neuron.2006.04.016&volume=50&pages=575-587&publication_year=2006&author=Wojcik%2CSM each month?
• Financial intake of https://doi.org/10.1002%2F1526-968X%28200011%2F12%2928%3A3%2F4%3C147%3A%3AAID-GENE90%3E3.0.CO%3B2-G
• How much money does http://scholar.google.com/scholar_lookup?&title=&journal=Genesis&doi=10.1002%2F1526-968X%28200011%2F12%2928%3A3%2F4%3C147%3A%3AAID-GENE90%3E3.0.CO%3B2-G&volume=28&pages=147-155&publication_year=2000&author=Novak%2CA&author=Guo%2CC&author=Yang%2CW&author=Nagy%2CA&author=Lobe%2CCG make?
• Earnings of https://doi.org/10.1016%2Fj.cmet.2007.04.001
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=&journal=Cell%20Metab.&doi=10.1016%2Fj.cmet.2007.04.001&volume=5&pages=383-393&publication_year=2007&author=Tong%2CQ
• How much does https://doi.org/10.1210%2Fen.2003-1596 bring in each month?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=&journal=Endocrinology&doi=10.1210%2Fen.2003-1596&volume=145&pages=2607-2612&publication_year=2004&author=Chen%2CHY
• How much does https://doi.org/10.1038%2Fnature06098 pull in monthly?
• How much income is http://scholar.google.com/scholar_lookup?&title=&journal=Nature&doi=10.1038%2Fnature06098&volume=449&pages=228-232&publication_year=2007&author=Parton%2CLE earning monthly?
• What's https://doi.org/10.1016%2FS0896-6273%2803%2900063-1's gross income?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=&journal=Neuron&doi=10.1016%2FS0896-6273%2803%2900063-1&volume=37&pages=649-661&publication_year=2003&author=Cowley%2CMA
• https://doi.org/10.1038%2Fnn1455's total income per month
• How much revenue does http://scholar.google.com/scholar_lookup?&title=&journal=Nat.%20Neurosci.&doi=10.1038%2Fnn1455&volume=8&pages=571-578&publication_year=2005&author=Cone%2CRD bring in?
• https://doi.org/10.1016%2Fj.peptides.2006.08.036 income
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=&journal=Peptides&doi=10.1016%2Fj.peptides.2006.08.036&volume=28&pages=214-225&publication_year=2007&author=Luquet%2CS&author=Phillips%2CCT&author=Palmiter%2CRD?
• How much cash flow does https://citation-needed.springer.com/v2/references/10.1038/nn.2167?format=refman&flavour=references have monthly?
• What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qingchun%20Tong?
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qingchun%20Tong%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Chian-Ping%20Ye gross monthly?
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Chian-Ping%20Ye%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Juli%20E%20Jones make?
• Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Juli%20E%20Jones%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joel%20K%20Elmquist
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joel%20K%20Elmquist%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bradford%20B%20Lowell pull in?
• What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bradford%20B%20Lowell%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know what's the income of https://static-content.springer.com/esm/art%3A10.1038%2Fnn.2167/MediaObjects/41593_2008_BFnn2167_MOESM7_ESM.pdf
• https://s100.copyright.com/AppDispatchServlet?title=Synaptic%20release%20of%20GABA%20by%20AgRP%20neurons%20is%20required%20for%20normal%20regulation%20of%20energy%20balance&author=Qingchun%20Tong%20et%20al&contentID=10.1038%2Fnn.2167©right=Springer%20Nature%20America%2C%20Inc.&publication=1097-6256&publicationDate=2008-08-10&publisherName=SpringerNature&orderBeanReset=true's financial summary
• How much money does https://citation-needed.springer.com/v2/references/10.1038/nn.2167?format=refman&flavour=citation make?
• https://doi.org/10.1038/s41467-024-49766-0's revenue stream
• What's the revenue for https://doi.org/10.1007/s12020-024-03755-x?
• What's https://doi.org/10.1038/s41467-023-40082-7's gross income?
• Get to know what's the income of https://doi.org/10.1038/s41586-023-06358-0
• Learn how profitable https://doi.org/10.1038/s41380-022-01872-5 is on a monthly basis
• How much profit does https://www.protocols.io/ make?
• Financial intake of https://www.natureindex.com/
• Check the income stats for http://www.naturechina.com
• Check the income stats for https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref