NATURE . COM {}

Matching Content Categories {📚}

• Education
• Science
• Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$536,300 per month
Our analysis indicates Nature.com generates between $357,503 and $983,134 monthly online from display ads.

Keywords {🔍}

article, cancer, google, scholar, cas, nature, massachusetts, usa, cell, access, medical, harvard, department, boston, content, matthew, metabolism, cells, school, jwl, research, institute, data, phosphoglycerate, serine, phgdh, human, carried, cookies, analysis, dehydrogenase, locasale, melman, sasaki, vander, heiden, metabolic, expression, breast, privacy, glycolytic, beroukhim, proliferation, open, cantley, biology, biochem, acid, experiments, information,

Topics {✒️}

nature portfolio permissions reprints privacy policy lc-ms-based targeted metabolomics author information authors advertising integrated data-mining platform integrative cancer research graduate research fellowship nature 463 nature 461 nature social media glucose-derived metabolic fluxes tissue research copy number data somatic copy-number alteration positive/negative ion–switching scientific advisors lc/ms/ms experiments triple-negative breast cancer glycine-biosynthesis-mediated pathway dana-farber cancer institute tumor development springerlink instant access permissions development amino acid sufficiency personal data data protection privacy fatty acid network human breast cancer breast cancer subtypes gc/ms experiments vander heiden rapidly proliferating cells expression profiling reveals enhanced serine production breast cancer res cancer microarray database american cancer society cancer genome discovery undifferentiated thyroid cancer metabolic defects caused metabolic flux analysis alternative glycolytic pathway european economic area explore content human cancers showed

Questions {❓}

• Can small molecular inhibitors that stop de novo serine synthesis be used in cancer treatment?
• Histone methyl transferases and demethylases: can they link metabolism and transcription?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
         description:Jason Locasale, Lewis Cantley, Matthew Vander Heiden and colleagues show that PHGDH is amplified in some human cancers and diverts a relatively large amount of glycolytic carbon into serine and glycine biosynthesis. They further show that PHGDH-amplified cancer cells become dependent on PHGDH for their growth, suggesting that the altered metabolic flux driven by this amplification contributes to oncogenesis. Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are used for alternative processes is poorly understood1,2. Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH). An analysis of human cancers showed that PHGDH is recurrently amplified in a genomic region of focal copy number gain most commonly found in melanoma. Decreasing PHGDH expression impaired proliferation in amplified cell lines. Increased expression was also associated with breast cancer subtypes, and ectopic expression of PHGDH in mammary epithelial cells disrupted acinar morphogenesis and induced other phenotypic alterations that may predispose cells to transformation. Our findings show that the diversion of glycolytic flux into a specific alternate pathway can be selected during tumor development and may contribute to the pathogenesis of human cancer.
         datePublished:2011-07-31T00:00:00Z
         dateModified:2011-07-31T00:00:00Z
         pageStart:869
         pageEnd:874
         sameAs:https://doi.org/10.1038/ng.890
         keywords:
            Cancer genetics
            Energy metabolism
            Oncogenesis
            Biomedicine
            general
            Human Genetics
            Cancer Research
            Agriculture
            Gene Function
            Animal Genetics and Genomics
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig4_HTML.jpg
         isPartOf:
            name:Nature Genetics
            issn:
               1546-1718
               1061-4036
            volumeNumber:43
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Jason W Locasale
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Alexandra R Grassian
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tamar Melman
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Costas A Lyssiotis
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Katherine R Mattaini
               affiliation:
                     name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Adam J Bass
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Cancer Program, Broad Institute of MIT and Harvard
                     address:
                        name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gregory Heffron
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Christian M Metallo
               affiliation:
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Taru Muranen
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hadar Sharfi
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Atsuo T Sasaki
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Dimitrios Anastasiou
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Edouard Mullarky
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Natalie I Vokes
               affiliation:
                     name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mika Sasaki
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Rameen Beroukhim
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Cancer Program, Broad Institute of MIT and Harvard
                     address:
                        name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                        type:PostalAddress
                     type:Organization
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gregory Stephanopoulos
               affiliation:
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Azra H Ligon
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Brigham and Women's Hospital
                     address:
                        name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Matthew Meyerson
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Cancer Program, Broad Institute of MIT and Harvard
                     address:
                        name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                        type:PostalAddress
                     type:Organization
                     name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Andrea L Richardson
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Brigham and Women's Hospital
                     address:
                        name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lynda Chin
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Harvard Medical School
                     address:
                        name:Department of Dermatology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gerhard Wagner
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:John M Asara
               affiliation:
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Joan S Brugge
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lewis C Cantley
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Department of Systems Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Beth Israel Deaconess Medical Center
                     address:
                        name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Matthew G Vander Heiden
               affiliation:
                     name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
                     name:Dana-Farber Cancer Institute, Harvard Medical School
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
      description:Jason Locasale, Lewis Cantley, Matthew Vander Heiden and colleagues show that PHGDH is amplified in some human cancers and diverts a relatively large amount of glycolytic carbon into serine and glycine biosynthesis. They further show that PHGDH-amplified cancer cells become dependent on PHGDH for their growth, suggesting that the altered metabolic flux driven by this amplification contributes to oncogenesis. Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are used for alternative processes is poorly understood1,2. Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH). An analysis of human cancers showed that PHGDH is recurrently amplified in a genomic region of focal copy number gain most commonly found in melanoma. Decreasing PHGDH expression impaired proliferation in amplified cell lines. Increased expression was also associated with breast cancer subtypes, and ectopic expression of PHGDH in mammary epithelial cells disrupted acinar morphogenesis and induced other phenotypic alterations that may predispose cells to transformation. Our findings show that the diversion of glycolytic flux into a specific alternate pathway can be selected during tumor development and may contribute to the pathogenesis of human cancer.
      datePublished:2011-07-31T00:00:00Z
      dateModified:2011-07-31T00:00:00Z
      pageStart:869
      pageEnd:874
      sameAs:https://doi.org/10.1038/ng.890
      keywords:
         Cancer genetics
         Energy metabolism
         Oncogenesis
         Biomedicine
         general
         Human Genetics
         Cancer Research
         Agriculture
         Gene Function
         Animal Genetics and Genomics
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_Article_BFng890_Fig4_HTML.jpg
      isPartOf:
         name:Nature Genetics
         issn:
            1546-1718
            1061-4036
         volumeNumber:43
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Jason W Locasale
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Alexandra R Grassian
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tamar Melman
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Costas A Lyssiotis
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Katherine R Mattaini
            affiliation:
                  name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Adam J Bass
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Cancer Program, Broad Institute of MIT and Harvard
                  address:
                     name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gregory Heffron
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Christian M Metallo
            affiliation:
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Taru Muranen
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hadar Sharfi
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Atsuo T Sasaki
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dimitrios Anastasiou
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Edouard Mullarky
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Natalie I Vokes
            affiliation:
                  name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mika Sasaki
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rameen Beroukhim
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Cancer Program, Broad Institute of MIT and Harvard
                  address:
                     name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                     type:PostalAddress
                  type:Organization
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gregory Stephanopoulos
            affiliation:
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Azra H Ligon
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Brigham and Women's Hospital
                  address:
                     name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Matthew Meyerson
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Cancer Program, Broad Institute of MIT and Harvard
                  address:
                     name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
                     type:PostalAddress
                  type:Organization
                  name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Andrea L Richardson
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Brigham and Women's Hospital
                  address:
                     name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lynda Chin
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Harvard Medical School
                  address:
                     name:Department of Dermatology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gerhard Wagner
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:John M Asara
            affiliation:
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Joan S Brugge
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lewis C Cantley
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Department of Systems Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Beth Israel Deaconess Medical Center
                  address:
                     name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Matthew G Vander Heiden
            affiliation:
                  name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
                  name:Dana-Farber Cancer Institute, Harvard Medical School
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Genetics
      issn:
         1546-1718
         1061-4036
      volumeNumber:43
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
      address:
         name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Cancer Program, Broad Institute of MIT and Harvard
      address:
         name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
      address:
         name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Cancer Program, Broad Institute of MIT and Harvard
      address:
         name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Brigham and Women's Hospital
      address:
         name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Cancer Program, Broad Institute of MIT and Harvard
      address:
         name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
         type:PostalAddress
      name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Brigham and Women's Hospital
      address:
         name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Dermatology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Systems Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Beth Israel Deaconess Medical Center
      address:
         name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
         type:PostalAddress
      name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
      address:
         name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Jason W Locasale
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Alexandra R Grassian
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Tamar Melman
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Costas A Lyssiotis
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Katherine R Mattaini
      affiliation:
            name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
            address:
               name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Adam J Bass
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Cancer Program, Broad Institute of MIT and Harvard
            address:
               name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Gregory Heffron
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Christian M Metallo
      affiliation:
            name:Massachusetts Institute of Technology
            address:
               name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Taru Muranen
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Hadar Sharfi
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Atsuo T Sasaki
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Dimitrios Anastasiou
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Edouard Mullarky
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Natalie I Vokes
      affiliation:
            name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
            address:
               name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Mika Sasaki
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Rameen Beroukhim
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Cancer Program, Broad Institute of MIT and Harvard
            address:
               name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
               type:PostalAddress
            type:Organization
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Gregory Stephanopoulos
      affiliation:
            name:Massachusetts Institute of Technology
            address:
               name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Azra H Ligon
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Brigham and Women's Hospital
            address:
               name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
               type:PostalAddress
            type:Organization
      name:Matthew Meyerson
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Cancer Program, Broad Institute of MIT and Harvard
            address:
               name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
               type:PostalAddress
            type:Organization
            name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Andrea L Richardson
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Brigham and Women's Hospital
            address:
               name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
               type:PostalAddress
            type:Organization
      name:Lynda Chin
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Harvard Medical School
            address:
               name:Department of Dermatology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Gerhard Wagner
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:John M Asara
      affiliation:
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      name:Joan S Brugge
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Lewis C Cantley
      affiliation:
            name:Harvard Medical School
            address:
               name:Department of Systems Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Beth Israel Deaconess Medical Center
            address:
               name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Matthew G Vander Heiden
      affiliation:
            name:Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
            address:
               name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
            name:Dana-Farber Cancer Institute, Harvard Medical School
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
      name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
      name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
      name:Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Cancer Program, Broad Institute of MIT and Harvard, Cambridge, USA
      name:Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
      name:Department of Dermatology, Harvard Medical School, Boston, USA
      name:Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Department of Systems Biology, Harvard Medical School, Boston, USA
      name:Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, USA
      name:Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/NatureGenet
• https://twitter.com/NatureGenet

External Links {🔗}(127)

• What are the earnings of https://link.springer.com/article/10.1038/ng.890?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
• What is the monthly revenue of https://doi.org/10.1126%2Fscience.1160809?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Understanding%20the%20Warburg%20effect%3A%20the%20metabolic%20requirements%20of%20cell%20proliferation&journal=Science&doi=10.1126%2Fscience.1160809&volume=324&pages=1029-1033&publication_year=2009&author=Vander%20Heiden%2CMG&author=Cantley%2CLC&author=Thompson%2CCB?
• Learn how profitable https://doi.org/10.1016%2Fj.cmet.2007.10.002 is on a monthly basis
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=The%20biology%20of%20cancer%3A%20metabolic%20reprogramming%20fuels%20cell%20growth%20and%20proliferation&journal=Cell%20Metab.&doi=10.1016%2Fj.cmet.2007.10.002&volume=7&pages=11-20&publication_year=2008&author=DeBerardinis%2CRJ&author=Lum%2CJJ&author=Hatzivassiliou%2CG&author=Thompson%2CCB each month?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Ueber%20den%20Stoffwechsel%20der%20Tumoren&journal=Biochem.%20Z.&volume=152&pages=319-344&publication_year=1924&author=Warburg%2CO&author=Posener%2CK&author=Negelein%2CE?
• What is the earnings of https://doi.org/10.1016%2F0009-2614%2880%2980041-8?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Natural%20abundance%20nitrogen-15%20NMR%20by%20enhanced%20heteronuclear%20spectroscopy&journal=Chem.%20Phys.%20Lett.&doi=10.1016%2F0009-2614%2880%2980041-8&volume=69&pages=185-189&publication_year=1980&author=Bodenhausen%2CG&author=Ruben%2CDJ making per month?
• Revenue of https://doi.org/10.1042%2Fbj3080761
• Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Glucose%20contribution%20to%20nucleic%20acid%20base%20synthesis%20in%20proliferating%20hepatoma%20cells%3A%20a%20glycine-biosynthesis-mediated%20pathway&journal=Biochem.%20J.&doi=10.1042%2Fbj3080761&volume=308&pages=761-767&publication_year=1995&author=Bismut%2CH&author=Caron%2CM&author=Coudray-Lucas%2CC&author=Capeau%2CJ
• How much revenue does https://doi.org/10.1042%2Fbj2450609 generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20modulation%20of%20serine%20metabolism%20in%20hepatoma%203924A%20during%20different%20phases%20of%20cellular%20proliferation%20in%20culture&journal=Biochem.%20J.&doi=10.1042%2Fbj2450609&volume=245&pages=609-612&publication_year=1987&author=Snell%2CK&author=Natsumeda%2CY&author=Weber%2CG produce monthly?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=13270262 generate monthly?
• How much money does http://scholar.google.com/scholar_lookup?&title=The%20biosynthesis%20of%20free%20glycine%20and%20serine%20by%20tumors&journal=Cancer%20Res.&volume=15&pages=715-718&publication_year=1955&author=Kit%2CS generate?
• What's the revenue for https://doi.org/10.1042%2Fbj20021785?
• Profit of http://scholar.google.com/scholar_lookup?&title=L-serine%20in%20disease%20and%20development&journal=Biochem.%20J.&doi=10.1042%2Fbj20021785&volume=371&pages=653-661&publication_year=2003&author=de%20Koning%2CTJ
• What's the financial gain of https://doi.org/10.1042%2Fbj3230365?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Cloning%2C%20sequencing%20and%20expression%20of%20rat%20liver%203-phosphoglycerate%20dehydrogenase&journal=Biochem.%20J.&doi=10.1042%2Fbj3230365&volume=323&pages=365-370&publication_year=1997&author=Achouri%2CY&author=Rider%2CMH&author=Van%20Schaftingen%2CE&author=Robbi%2CM
• Discover the revenue of https://doi.org/10.1016%2Fj.jchromb.2008.04.031
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Analytical%20strategies%20for%20LC-MS-based%20targeted%20metabolomics&journal=J.%20Chromatogr.%20B%20Analyt.%20Technol.%20Biomed.%20Life%20Sci.&doi=10.1016%2Fj.jchromb.2008.04.031&volume=871&pages=236-242&publication_year=2008&author=Lu%2CW&author=Bennett%2CBD&author=Rabinowitz%2CJD?
• How much does https://doi.org/10.1038%2Fnature08822 earn?
• What's the income of http://scholar.google.com/scholar_lookup?&title=The%20landscape%20of%20somatic%20copy-number%20alteration%20across%20human%20cancers&journal=Nature&doi=10.1038%2Fnature08822&volume=463&pages=899-905&publication_year=2010&author=Beroukhim%2CR?
• What's the profit of https://doi.org/10.1158%2F0008-5472.CAN-07-2102?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=A%20comparison%20of%20DNA%20copy%20number%20profiling%20platforms&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-07-2102&volume=67&pages=10173-10180&publication_year=2007&author=Greshock%2CJ produce monthly?
• How much does https://doi.org/10.1126%2Fscience.3798106 gross monthly?
• How much money does http://scholar.google.com/scholar_lookup?&title=Human%20breast%20cancer%3A%20correlation%20of%20relapse%20and%20survival%20with%20amplification%20of%20the%20HER-2%2Fneu%20oncogene&journal=Science&doi=10.1126%2Fscience.3798106&volume=235&pages=177-182&publication_year=1987&author=Slamon%2CDJ make?
• How much cash flow does https://doi.org/10.1016%2Fj.cell.2009.02.024 have monthly?
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Principles%20of%20cancer%20therapy%3A%20oncogene%20and%20non-oncogene%20addiction&journal=Cell&doi=10.1016%2Fj.cell.2009.02.024&volume=136&pages=823-837&publication_year=2009&author=Luo%2CJ&author=Solimini%2CNL&author=Elledge%2CSJ?
• Discover the revenue of https://link.springer.com/doi/10.1007/s10549-010-0848-5
• How much does http://scholar.google.com/scholar_lookup?&title=Enhanced%20serine%20production%20by%20bone%20metastatic%20breast%20cancer%20cells%20stimulates%20osteoclastogenesis&journal=Breast%20Cancer%20Res.%20Treat.&doi=10.1007%2Fs10549-010-0848-5&volume=125&pages=421-430&publication_year=2011&author=Pollari%2CS generate monthly?
• How much does https://doi.org/10.1056%2FNEJMra1001389 generate monthly?
• http://scholar.google.com/scholar_lookup?&title=Triple-negative%20breast%20cancer&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMra1001389&volume=363&pages=1938-1948&publication_year=2010&author=Foulkes%2CWD&author=Smith%2CIE&author=Reis-Filho%2CJ's total income per month
• How much revenue does https://doi.org/10.1038%2Fnrc1695 bring in?
• How much does http://scholar.google.com/scholar_lookup?&title=Modelling%20glandular%20epithelial%20cancers%20in%20three-dimensional%20cultures&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1695&volume=5&pages=675-688&publication_year=2005&author=Debnath%2CJ&author=Brugge%2CJS gross monthly?
• What's the financial gain of https://doi.org/10.1038%2Fnature08268?
• http://scholar.google.com/scholar_lookup?&title=Antioxidant%20and%20oncogene%20rescue%20of%20metabolic%20defects%20caused%20by%20loss%20of%20matrix%20attachment&journal=Nature&doi=10.1038%2Fnature08268&volume=461&pages=109-113&publication_year=2009&author=Schafer%2CZT income
• How much money does https://doi.org/10.1002%2Fhumu.20934 generate?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Novel%20mutations%20in%203-phosphoglycerate%20dehydrogenase%20%28PHGDH%29%20are%20distributed%20throughout%20the%20protein%20and%20result%20in%20altered%20enzyme%20kinetics&journal=Hum.%20Mutat.&doi=10.1002%2Fhumu.20934&volume=30&pages=749-756&publication_year=2009&author=Tabatabaie%2CL?
• How much does https://doi.org/10.1056%2FNEJMe0810213 rake in every month?
• How much income does http://scholar.google.com/scholar_lookup?&title=Metabolic%20enzymes%20as%20oncogenes%20or%20tumor%20suppressors&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMe0810213&volume=360&pages=813-815&publication_year=2009&author=Thompson%2CCB have?
• What's the income of https://doi.org/10.1016%2Fj.cmet.2010.09.004?
• How much does http://scholar.google.com/scholar_lookup?&title=Histone%20methyl%20transferases%20and%20demethylases%3A%20can%20they%20link%20metabolism%20and%20transcription%3F&journal=Cell%20Metab.&doi=10.1016%2Fj.cmet.2010.09.004&volume=12&pages=321-327&publication_year=2010&author=Teperino%2CR&author=Schoonjans%2CK&author=Auwerx%2CJ earn?
• How much does https://doi.org/10.1016%2Fj.cell.2009.11.027 pull in?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Monoacylglycerol%20lipase%20regulates%20a%20fatty%20acid%20network%20that%20promotes%20cancer%20pathogenesis&journal=Cell&doi=10.1016%2Fj.cell.2009.11.027&volume=140&pages=49-61&publication_year=2010&author=Nomura%2CDK is on a monthly basis
• How much does https://doi.org/10.1074%2Fjbc.273.23.14484 bring in each month?
• http://scholar.google.com/scholar_lookup?&title=Amino%20acid%20sufficiency%20and%20mTOR%20regulate%20p70%20S6%20kinase%20and%20eIF-4E%20BP1%20through%20a%20common%20effector%20mechanism&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.273.23.14484&volume=273&pages=14484-14494&publication_year=1998&author=Hara%2CK's revenue stream
• Financial intake of https://doi.org/10.1126%2Fscience.1188015
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Evidence%20for%20an%20alternative%20glycolytic%20pathway%20in%20rapidly%20proliferating%20cells&journal=Science&doi=10.1126%2Fscience.1188015&volume=329&pages=1492-1499&publication_year=2010&author=Vander%20Heiden%2CMG bring in?
• What's the monthly income of https://link.springer.com/doi/10.1186/1741-7007-8-88?
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Altered%20metabolism%20in%20cancer&journal=BMC%20Biol.&doi=10.1186%2F1741-7007-8-88&volume=8&publication_year=2010&author=Locasale%2CJW&author=Cantley%2CLC?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20424262 gross monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Ammonia%20derived%20from%20glutaminolysis%20is%20a%20diffusible%20regulator%20of%20autophagy&journal=Sci.%20Signal.&volume=3&publication_year=2010&author=Eng%2CCH&author=Yu%2CK&author=Lucas%2CJ&author=White%2CE&author=Abraham%2CRT gross monthly?
• How much profit does https://doi.org/10.1021%2Fac0708893 make?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Accurate%20assessment%20of%20amino%20acid%20mass%20isotopomer%20distributions%20for%20metabolic%20flux%20analysis&journal=Anal.%20Chem.&doi=10.1021%2Fac0708893&volume=79&pages=7554-7559&publication_year=2007&author=Antoniewicz%2CMR&author=Kelleher%2CJK&author=Stephanopoulos%2CG earns monthly
• How much money does https://doi.org/10.1002%2F%28SICI%291096-9888%28199603%2931%3A3%3C255%3A%3AAID-JMS290%3E3.0.CO%3B2-3 make?
• How much does http://scholar.google.com/scholar_lookup?&title=Correction%20of%2013C%20mass%20isotopomer%20distributions%20for%20natural%20stable%20isotope%20abundance&journal=J.%20Mass%20Spectrom.&doi=10.1002%2F%28SICI%291096-9888%28199603%2931%3A3%3C255%3A%3AAID-JMS290%3E3.0.CO%3B2-3&volume=31&pages=255-262&publication_year=1996&author=Fernandez%2CCA&author=Des%20Rosiers%2CC&author=Previs%2CSF&author=David%2CF&author=Brunengraber%2CH net monthly?
• Earnings of https://doi.org/10.1016%2Fj.ccr.2006.01.013
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=X%20chromosomal%20abnormalities%20in%20basal-like%20human%20breast%20cancer&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2006.01.013&volume=9&pages=121-132&publication_year=2006&author=Richardson%2CAL?
• Learn about the earnings of https://doi.org/10.1158%2F0008-5472.CAN-04-0731
• See how much http://scholar.google.com/scholar_lookup?&title=Expression%20profiling%20reveals%20novel%20pathways%20in%20the%20transformation%20of%20melanocytes%20to%20melanomas&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-04-0731&volume=64&pages=5270-5282&publication_year=2004&author=Hoek%2CK makes per month
• How much profit does https://doi.org/10.1016%2FS1476-5586%2804%2980047-2 generate?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=ONCOMINE%3A%20a%20cancer%20microarray%20database%20and%20integrated%20data-mining%20platform&journal=Neoplasia&doi=10.1016%2FS1476-5586%2804%2980047-2&volume=6&pages=1-6&publication_year=2004&author=Rhodes%2CDR?
• https://citation-needed.springer.com/v2/references/10.1038/ng.890?format=refman&flavour=references income
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jason%20W%20Locasale earns monthly
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jason%20W%20Locasale%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alexandra%20R%20Grassian produce monthly?
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alexandra%20R%20Grassian%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tamar%20Melman
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tamar%20Melman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Costas%20A%20Lyssiotis make?
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Costas%20A%20Lyssiotis%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Katherine%20R%20Mattaini is on a monthly basis
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Katherine%20R%20Mattaini%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Adam%20J%20Bass rake in every month?
• What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Adam%20J%20Bass%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gregory%20Heffron?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gregory%20Heffron%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Christian%20M%20Metallo
• What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Christian%20M%20Metallo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Taru%20Muranen
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Taru%20Muranen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hadar%20Sharfi's revenue stream
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hadar%20Sharfi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Atsuo%20T%20Sasaki's total income per month
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Atsuo%20T%20Sasaki%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dimitrios%20Anastasiou's gross income?
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dimitrios%20Anastasiou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Edouard%20Mullarky have monthly?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Edouard%20Mullarky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Natalie%20I%20Vokes?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Natalie%20I%20Vokes%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mika%20Sasaki make?
• Earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mika%20Sasaki%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rameen%20Beroukhim?
• Monthly income for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rameen%20Beroukhim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gregory%20Stephanopoulos generate?
• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gregory%20Stephanopoulos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Azra%20H%20Ligon income
• What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Azra%20H%20Ligon%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Matthew%20Meyerson
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Matthew%20Meyerson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Andrea%20L%20Richardson's gross income?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Andrea%20L%20Richardson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lynda%20Chin produce monthly?
• What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lynda%20Chin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gerhard%20Wagner?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gerhard%20Wagner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=John%20M%20Asara?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22John%20M%20Asara%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• See how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joan%20S%20Brugge makes per month
• Explore the financials of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joan%20S%20Brugge%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lewis%20C%20Cantley have?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lewis%20C%20Cantley%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Matthew%20G%20Vander%20Heiden
• What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Matthew%20G%20Vander%20Heiden%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fng.890/MediaObjects/41588_2011_BFng890_MOESM13_ESM.pdf pull in monthly?
• Learn how profitable https://s100.copyright.com/AppDispatchServlet?title=Phosphoglycerate%20dehydrogenase%20diverts%20glycolytic%20flux%20and%20contributes%20to%20oncogenesis&author=Jason%20W%20Locasale%20et%20al&contentID=10.1038%2Fng.890©right=Springer%20Nature%20America%2C%20Inc.&publication=1061-4036&publicationDate=2011-07-31&publisherName=SpringerNature&orderBeanReset=true is on a monthly basis
• Financial intake of https://citation-needed.springer.com/v2/references/10.1038/ng.890?format=refman&flavour=citation
• What's the profit of https://doi.org/10.1007/s00441-023-03851-w?
• How much income is https://doi.org/10.1038/s41467-024-45366-0 earning monthly?
• What's the financial outcome of https://doi.org/10.1186/s12859-023-05211-5?
• How much income is https://doi.org/10.1186/s13046-023-02927-3 earning monthly?
• How much does https://doi.org/10.1038/s41598-023-43022-z earn?
• What's the revenue for https://www.protocols.io/?
• How much money does https://www.natureindex.com/ generate?
• What's http://www.naturechina.com's gross income?
• https://www.natureasia.com/ja-jp's total income per month

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref