
NATURE . COM {
}
Title:
FOXA1 is a key determinant of estrogen receptor function and endocrine response | Nature Genetics
Description:
Jason Carroll and colleagues report that the forkhead protein FOXA1 is an important determinant of estrogen receptor binding and show that expression of FOXA1 in non–breast cancer cells is sufficient to confer estrogen receptor binding and response to endocrine treatment. Estrogen receptor-α (ER) is the key feature of most breast cancers and binding of ER to the genome correlates with expression of the Forkhead protein FOXA1 (also called HNF3α). Here we show that FOXA1 is a key determinant that can influence differential interactions between ER and chromatin. Almost all ER-chromatin interactions and gene expression changes depended on the presence of FOXA1 and FOXA1 influenced genome-wide chromatin accessibility. Furthermore, we found that CTCF was an upstream negative regulator of FOXA1-chromatin interactions. In estrogen-responsive breast cancer cells, the dependency on FOXA1 for tamoxifen-ER activity was absolute; in tamoxifen-resistant cells, ER binding was independent of ligand but depended on FOXA1. Expression of FOXA1 in non-breast cancer cells can alter ER binding and function. As such, FOXA1 is a major determinant of estrogen-ER activity and endocrine response in breast cancer cells.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Education
- Science
- Telecommunications
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.
Keywords {🔍}
article, google, scholar, cas, cancer, estrogen, breast, nature, foxa, receptor, cell, expression, chromatin, binding, cells, access, content, gene, carroll, res, cookies, analysis, genome, transcription, research, privacy, data, genetics, response, lines, nat, genes, regulation, mol, human, alpha, factor, function, information, key, determinant, hurtado, holmes, rossinnes, schmidt, interactions, accessibility, rev, dev, regulatory,
Topics {✒️}
nature portfolio permissions reprints privacy policy cancer research uk enhancer-driven lineage-specific transcription cambridge research institute advertising estrogen receptor-regulated transcription ccctc-binding factor confines nature 462 nature 406 nature social media endocrine-responsive breast cancer retinoic acid receptor-alpha p130–e2f4 complexes characteristic tamoxifen-resistant mcf-7 cells discover protein-dna interactions tamoxifen-dependent gene expression tissue-specific transcription author correspondence springerlink instant access estrogen receptor alpha permissions personal data breast cancer cells breast cancer cells chromatin accessibility profiling enhanced estrogen receptor data protection breast cancer–correlation tamoxifen-resistant cells human breast tumours breast tumor subtypes estrogen receptor function androgen receptor interacts breast cancer res estrogen-er activity estrogen receptors alpha hutchison whampoa limited gene expression profiling endogenous gene expression privacy foxa1-bound enhancers upstream negative regulator competing financial interests chromosome-wide mapping tamoxifen-er activity genome-wide analysis cell cycle progression
Questions {❓}
- Estrogen receptor null mice: what have we learned and where will they lead us?
Schema {🗺️}
WebPage:
mainEntity:
headline:FOXA1 is a key determinant of estrogen receptor function and endocrine response
description:Jason Carroll and colleagues report that the forkhead protein FOXA1 is an important determinant of estrogen receptor binding and show that expression of FOXA1 in nonâbreast cancer cells is sufficient to confer estrogen receptor binding and response to endocrine treatment. Estrogen receptor-α (ER) is the key feature of most breast cancers and binding of ER to the genome correlates with expression of the Forkhead protein FOXA1 (also called HNF3α). Here we show that FOXA1 is a key determinant that can influence differential interactions between ER and chromatin. Almost all ER-chromatin interactions and gene expression changes depended on the presence of FOXA1 and FOXA1 influenced genome-wide chromatin accessibility. Furthermore, we found that CTCF was an upstream negative regulator of FOXA1-chromatin interactions. In estrogen-responsive breast cancer cells, the dependency on FOXA1 for tamoxifen-ER activity was absolute; in tamoxifen-resistant cells, ER binding was independent of ligand but depended on FOXA1. Expression of FOXA1 in non-breast cancer cells can alter ER binding and function. As such, FOXA1 is a major determinant of estrogen-ER activity and endocrine response in breast cancer cells.
datePublished:2010-12-12T00:00:00Z
dateModified:2010-12-12T00:00:00Z
pageStart:27
pageEnd:33
sameAs:https://doi.org/10.1038/ng.730
keywords:
Breast cancer
Cancer genetics
Endocrinology
Biomedicine
general
Human Genetics
Cancer Research
Agriculture
Gene Function
Animal Genetics and Genomics
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig6_HTML.jpg
isPartOf:
name:Nature Genetics
issn:
1546-1718
1061-4036
volumeNumber:43
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Antoni Hurtado
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Kelly A Holmes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Caryn S Ross-Innes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Dominic Schmidt
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Jason S Carroll
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:FOXA1 is a key determinant of estrogen receptor function and endocrine response
description:Jason Carroll and colleagues report that the forkhead protein FOXA1 is an important determinant of estrogen receptor binding and show that expression of FOXA1 in nonâbreast cancer cells is sufficient to confer estrogen receptor binding and response to endocrine treatment. Estrogen receptor-α (ER) is the key feature of most breast cancers and binding of ER to the genome correlates with expression of the Forkhead protein FOXA1 (also called HNF3α). Here we show that FOXA1 is a key determinant that can influence differential interactions between ER and chromatin. Almost all ER-chromatin interactions and gene expression changes depended on the presence of FOXA1 and FOXA1 influenced genome-wide chromatin accessibility. Furthermore, we found that CTCF was an upstream negative regulator of FOXA1-chromatin interactions. In estrogen-responsive breast cancer cells, the dependency on FOXA1 for tamoxifen-ER activity was absolute; in tamoxifen-resistant cells, ER binding was independent of ligand but depended on FOXA1. Expression of FOXA1 in non-breast cancer cells can alter ER binding and function. As such, FOXA1 is a major determinant of estrogen-ER activity and endocrine response in breast cancer cells.
datePublished:2010-12-12T00:00:00Z
dateModified:2010-12-12T00:00:00Z
pageStart:27
pageEnd:33
sameAs:https://doi.org/10.1038/ng.730
keywords:
Breast cancer
Cancer genetics
Endocrinology
Biomedicine
general
Human Genetics
Cancer Research
Agriculture
Gene Function
Animal Genetics and Genomics
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_Article_BFng730_Fig6_HTML.jpg
isPartOf:
name:Nature Genetics
issn:
1546-1718
1061-4036
volumeNumber:43
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Antoni Hurtado
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Kelly A Holmes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Caryn S Ross-Innes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Dominic Schmidt
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
type:Person
name:Jason S Carroll
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Genetics
issn:
1546-1718
1061-4036
volumeNumber:43
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Antoni Hurtado
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
name:Kelly A Holmes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
name:Caryn S Ross-Innes
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
name:Dominic Schmidt
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
name:Jason S Carroll
affiliation:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre
address:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
name:Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(104)
- What are the earnings of https://link.springer.com/article/10.1038/ng.730?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- How much income is https://doi.org/10.1038%2Fnrc721 earning monthly?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Endocrine-responsive%20breast%20cancer%20and%20strategies%20for%20combating%20resistance&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc721&volume=2&pages=101-112&publication_year=2002&author=Ali%2CS&author=Coombes%2CRC
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11171938 earns monthly
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Cellular%20and%20molecular%20pharmacology%20of%20antiestrogen%20action%20and%20resistance&journal=Pharmacol.%20Rev.&volume=53&pages=25-71&publication_year=2001&author=Clarke%2CR&author=Leonessa%2CF&author=Welch%2CJN&author=Skaar%2CTC?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10652267?
- Revenue of http://scholar.google.com/scholar_lookup?&title=The%20coregulator%20exchange%20in%20transcriptional%20functions%20of%20nuclear%20receptors&journal=Genes%20Dev.&volume=14&pages=121-141&publication_year=2000&author=Glass%2CCK&author=Rosenfeld%2CMG
- How much does https://doi.org/10.1210%2Fme.2007-0546 rake in every month?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Nuclear%20receptor%20location%20analyses%20in%20mammalian%20genomes%3A%20from%20gene%20regulation%20to%20regulatory%20networks&journal=Mol.%20Endocrinol.&doi=10.1210%2Fme.2007-0546&volume=22&pages=1999-2011&publication_year=2008&author=Deblois%2CG&author=Giguere%2CV?
- Learn about the earnings of https://doi.org/10.1038%2Fnature08497
- How much does http://scholar.google.com/scholar_lookup?&title=An%20oestrogen-receptor-alpha-bound%20human%20chromatin%20interactome&journal=Nature&doi=10.1038%2Fnature08497&volume=462&pages=58-64&publication_year=2009&author=Fullwood%2CMJ gross monthly?
- How much does https://doi.org/10.1038%2Fng1901 net monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Genome-wide%20analysis%20of%20estrogen%20receptor%20binding%20sites&journal=Nat.%20Genet.&doi=10.1038%2Fng1901&volume=38&pages=1289-1297&publication_year=2006&author=Carroll%2CJS generate monthly?
- Financial intake of https://doi.org/10.1371%2Fjournal.pgen.0030087
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Whole-genome%20cartography%20of%20estrogen%20receptor%20alpha%20binding%20sites&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.0030087&volume=3&publication_year=2007&author=Lin%2CCY
- How much profit is https://doi.org/10.1038%2Femboj.2009.88 making per month?
- http://scholar.google.com/scholar_lookup?&title=ChIP-Seq%20of%20ERalpha%20and%20RNA%20polymerase%20II%20defines%20genes%20differentially%20responding%20to%20ligands&journal=EMBO%20J.&doi=10.1038%2Femboj.2009.88&volume=28&pages=1418-1428&publication_year=2009&author=Welboren%2CWJ's financial summary
- Income figures for https://doi.org/10.1073%2Fpnas.0505575102
- http://scholar.google.com/scholar_lookup?&title=Location%20analysis%20of%20estrogen%20receptor%20alpha%20target%20promoters%20reveals%20that%20FOXA1%20defines%20a%20domain%20of%20the%20estrogen%20response&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0505575102&volume=102&pages=11651-11656&publication_year=2005&author=Lagani%C3%A8re%2CJ income
- https://doi.org/10.1016%2Fj.cell.2005.05.008's total income per month
- How much does http://scholar.google.com/scholar_lookup?&title=Chromosome-wide%20mapping%20of%20estrogen%20receptor%20binding%20reveals%20long-range%20regulation%20requiring%20the%20forkhead%20protein%20FoxA1&journal=Cell&doi=10.1016%2Fj.cell.2005.05.008&volume=122&pages=33-43&publication_year=2005&author=Carroll%2CJS net monthly?
- What's https://doi.org/10.1016%2Fj.cell.2008.01.018's gross income?
- How much money does http://scholar.google.com/scholar_lookup?&title=FoxA1%20translates%20epigenetic%20signatures%20into%20enhancer-driven%20lineage-specific%20transcription&journal=Cell&doi=10.1016%2Fj.cell.2008.01.018&volume=132&pages=958-970&publication_year=2008&author=Lupien%2CM make?
- Get to know https://doi.org/10.1093%2Femboj%2F17.1.244's earnings
- http://scholar.google.com/scholar_lookup?&title=Binding%20of%20the%20winged-helix%20transcription%20factor%20HNF3%20to%20a%20linker%20histone%20site%20on%20the%20nucleosome&journal=EMBO%20J.&doi=10.1093%2Femboj%2F17.1.244&volume=17&pages=244-254&publication_year=1998&author=Cirillo%2CLA's financial summary
- How much money does https://doi.org/10.1016%2FS1097-2765%2802%2900459-8 generate?
- How much money does http://scholar.google.com/scholar_lookup?&title=Opening%20of%20compacted%20chromatin%20by%20early%20developmental%20transcription%20factors%20HNF3%20%28FoxA%29%20and%20GATA-4&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2802%2900459-8&volume=9&pages=279-289&publication_year=2002&author=Cirillo%2CLA generate?
- How much money does https://doi.org/10.1158%2F1078-0432.CCR-07-0122 generate?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=FOXA1%20expression%20in%20breast%20cancer%E2%80%93correlation%20with%20luminal%20subtype%20A%20and%20survival&journal=Clin.%20Cancer%20Res.&doi=10.1158%2F1078-0432.CCR-07-0122&volume=13&pages=4415-4421&publication_year=2007&author=Badve%2CS is on a monthly basis
- What's the financial intake of https://doi.org/10.1038%2F35021093?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Molecular%20portraits%20of%20human%20breast%20tumours&journal=Nature&doi=10.1038%2F35021093&volume=406&pages=747-752&publication_year=2000&author=Perou%2CCM earns monthly
- How profitable is https://doi.org/10.1073%2Fpnas.0932692100?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Repeated%20observation%20of%20breast%20tumor%20subtypes%20in%20independent%20gene%20expression%20data%20sets&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0932692100&volume=100&pages=8418-8423&publication_year=2003&author=Sorlie%2CT?
- https://doi.org/10.1023%2FB%3ABREA.0000014042.54925.cc's financial summary
- How much income is http://scholar.google.com/scholar_lookup?&title=Relevance%20of%20breast%20cancer%20cell%20lines%20as%20models%20for%20breast%20tumours%3A%20an%20update&journal=Breast%20Cancer%20Res.%20Treat.&doi=10.1023%2FB%3ABREA.0000014042.54925.cc&volume=83&pages=249-289&publication_year=2004&author=Lacroix%2CM&author=Leclercq%2CG earning monthly?
- How much does https://link.springer.com/doi/10.1186/gb-2008-9-9-r137 bring in each month?
- Get to know http://scholar.google.com/scholar_lookup?&title=Model-based%20analysis%20of%20ChIP-seq%20%28MACS%29&journal=Genome%20Biol.&doi=10.1186%2Fgb-2008-9-9-r137&volume=9&publication_year=2008&author=Zhang%2CY's earnings
- Get to know what's the income of https://doi.org/10.1101%2Fgad.552910
- How much money does http://scholar.google.com/scholar_lookup?&title=Cooperative%20interaction%20between%20retinoic%20acid%20receptor-alpha%20and%20estrogen%20receptor%20in%20breast%20cancer&journal=Genes%20Dev.&doi=10.1101%2Fgad.552910&volume=24&pages=171-182&publication_year=2010&author=Ross-Innes%2CCS make?
- What's the monthly money flow for https://doi.org/10.1038%2Fnrd1031?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Tamoxifen%3A%20a%20most%20unlikely%20pioneering%20medicine&journal=Nat.%20Rev.%20Drug%20Discov.&doi=10.1038%2Fnrd1031&volume=2&pages=205-213&publication_year=2003&author=Jordan%2CVC?
- How much income is https://doi.org/10.1016%2FS0092-8674%2800%2900188-4 earning monthly?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Cofactor%20dynamics%20and%20sufficiency%20in%20estrogen%20receptor-regulated%20transcription&journal=Cell&doi=10.1016%2FS0092-8674%2800%2900188-4&volume=103&pages=843-852&publication_year=2000&author=Shang%2CY&author=Hu%2CX&author=DiRenzo%2CJ&author=Lazar%2CMA&author=Brown%2CM
- How much does https://doi.org/10.1158%2F0008-5472.CAN-03-3326 generate monthly?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Selective%20estrogen%20receptor%20modulators%3A%20discrimination%20of%20agonistic%20versus%20antagonistic%20activities%20by%20gene%20expression%20profiling%20in%20breast%20cancer%20cells&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-03-3326&volume=64&pages=1522-1533&publication_year=2004&author=Frasor%2CJ each month?
- How much money does https://doi.org/10.1210%2Fen.2002-220620 generate?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Elevated%20levels%20of%20epidermal%20growth%20factor%20receptor%2Fc-erbB2%20heterodimers%20mediate%20an%20autocrine%20growth%20regulatory%20pathway%20in%20tamoxifen-resistant%20MCF-7%20cells&journal=Endocrinology&doi=10.1210%2Fen.2002-220620&volume=144&pages=1032-1044&publication_year=2003&author=Knowlden%2CJM?
- Monthly income for https://doi.org/10.1002%2Fjcb.10633
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Estrogen%20receptor%20isoform-specific%20regulation%20of%20endogenous%20gene%20expression%20in%20human%20osteoblastic%20cell%20lines%20expressing%20either%20ERalpha%20or%20ERbeta&journal=J.%20Cell.%20Biochem.&doi=10.1002%2Fjcb.10633&volume=90&pages=315-326&publication_year=2003&author=Monroe%2CDG
- How much income does https://doi.org/10.1210%2Fme.2008-0100 have?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Unique%20ERalpha%20cistromes%20control%20cell%20type-specific%20gene%20regulation&journal=Mol.%20Endocrinol.&doi=10.1210%2Fme.2008-0100&volume=22&pages=2393-2406&publication_year=2008&author=Krum%2CSA?
- Check the income stats for https://doi.org/10.1210%2Fme.2004-0381
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Estrogen%20receptor%20alpha%20and%20beta%20heterodimers%20exert%20unique%20effects%20on%20estrogen-%20and%20tamoxifen-dependent%20gene%20expression%20in%20human%20U2OS%20osteosarcoma%20cells&journal=Mol.%20Endocrinol.&doi=10.1210%2Fme.2004-0381&volume=19&pages=1555-1568&publication_year=2005&author=Monroe%2CDG?
- See how much https://doi.org/10.1101%2Fgad.1446006 makes per month
- How much income is http://scholar.google.com/scholar_lookup?&title=A%20cell-type-specific%20transcriptional%20network%20required%20for%20estrogen%20regulation%20of%20cyclin%20D1%20and%20cell%20cycle%20progression%20in%20breast%20cancer&journal=Genes%20Dev.&doi=10.1101%2Fgad.1446006&volume=20&pages=2513-2526&publication_year=2006&author=Eeckhoute%2CJ&author=Carroll%2CJS&author=Geistlinger%2CTR&author=Torres-Arzayus%2CMI&author=Brown%2CM earning monthly?
- How much revenue does https://doi.org/10.1101%2Fgr.5533506 bring in?
- How much money does http://scholar.google.com/scholar_lookup?&title=FAIRE%20%28formaldehyde-assisted%20isolation%20of%20regulatory%20elements%29%20isolates%20active%20regulatory%20elements%20from%20human%20chromatin&journal=Genome%20Res.&doi=10.1101%2Fgr.5533506&volume=17&pages=877-885&publication_year=2007&author=Giresi%2CPG&author=Kim%2CJ&author=McDaniell%2CRM&author=Iyer%2CVR&author=Lieb%2CJD generate?
- How much does https://doi.org/10.1101%2Fgr.084582.108 generate monthly?
- http://scholar.google.com/scholar_lookup?&title=Cell-type%20selective%20chromatin%20remodeling%20defines%20the%20active%20subset%20of%20FOXA1-bound%20enhancers&journal=Genome%20Res.&doi=10.1101%2Fgr.084582.108&volume=19&pages=372-380&publication_year=2009&author=Eeckhoute%2CJ's total income per month
- How much does https://doi.org/10.1101%2Fgr.100479.109 gross monthly?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=A%20CTCF-independent%20role%20for%20cohesin%20in%20tissue-specific%20transcription&journal=Genome%20Res.&doi=10.1101%2Fgr.100479.109&volume=20&pages=578-588&publication_year=2010&author=Schmidt%2CD?
- How much does https://doi.org/10.1158%2F0008-5472.CAN-08-2632 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=CCCTC-binding%20factor%20confines%20the%20distal%20action%20of%20estrogen%20receptor&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-08-2632&volume=68&pages=9041-9049&publication_year=2008&author=Chan%2CCS&author=Song%2CJS earn?
- What's the total monthly financial gain of https://doi.org/10.1074%2Fjbc.M110.149658?
- Revenue of http://scholar.google.com/scholar_lookup?&title=CCCTC-binding%20factor%20acts%20upstream%20of%20FOXA1%20and%20demarcates%20the%20genomic%20response%20to%20estrogen&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M110.149658&volume=285&pages=28604-28613&publication_year=2010&author=Zhang%2CY
- What's https://doi.org/10.1210%2Fme.2009-0252's gross income?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Genome-wide%20dynamics%20of%20chromatin%20binding%20of%20estrogen%20receptors%20alpha%20and%20beta%3A%20mutual%20restriction%20and%20competitive%20site%20selection&journal=Mol.%20Endocrinol.&doi=10.1210%2Fme.2009-0252&volume=24&pages=47-59&publication_year=2010&author=Charn%2CTH make?
- What's the monthly income of https://doi.org/10.1074%2Fjbc.M305226200?
- http://scholar.google.com/scholar_lookup?&title=Enhanced%20estrogen%20receptor%20%28ER%29%20alpha%2C%20ERBB2%2C%20and%20MAPK%20signal%20transduction%20pathways%20operate%20during%20the%20adaptation%20of%20MCF-7%20cells%20to%20long%20term%20estrogen%20deprivation&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M305226200&volume=278&pages=30458-30468&publication_year=2003&author=Martin%2CLA income
- What's the total monthly financial gain of https://doi.org/10.1210%2Fedrv.20.3.0370?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Estrogen%20receptor%20null%20mice%3A%20what%20have%20we%20learned%20and%20where%20will%20they%20lead%20us%3F&journal=Endocr.%20Rev.&doi=10.1210%2Fedrv.20.3.0370&volume=20&pages=358-417&publication_year=1999&author=Couse%2CJF&author=Korach%2CKS produce monthly?
- How much money does https://doi.org/10.1101%2Fgad.399506 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=CTCF%20mediates%20long-range%20chromatin%20looping%20and%20local%20histone%20modification%20in%20the%20beta-globin%20locus&journal=Genes%20Dev.&doi=10.1101%2Fgad.399506&volume=20&pages=2349-2354&publication_year=2006&author=Splinter%2CE generate monthly?
- How much profit does https://doi.org/10.1016%2Fj.ccr.2006.10.008 generate?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=A%20collection%20of%20breast%20cancer%20cell%20lines%20for%20the%20study%20of%20functionally%20distinct%20cancer%20subtypes&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2006.10.008&volume=10&pages=515-527&publication_year=2006&author=Neve%2CRM?
- How much profit does https://doi.org/10.1016%2Fj.ymeth.2009.03.001 generate?
- Income figures for http://scholar.google.com/scholar_lookup?&title=ChIP-seq%3A%20Using%20high-throughput%20sequencing%20to%20discover%20protein-DNA%20interactions&journal=Methods&doi=10.1016%2Fj.ymeth.2009.03.001&volume=48&pages=240-248&publication_year=2009&author=Schmidt%2CD
- What is the monthly revenue of https://doi.org/10.1074%2Fjbc.M004424200?
- How much profit is http://scholar.google.com/scholar_lookup?&title=A%20pure%20estrogen%20antagonist%20inhibits%20cyclin%20E-Cdk2%20activity%20in%20MCF-7%20breast%20cancer%20cells%20and%20induces%20accumulation%20of%20p130%E2%80%93E2F4%20complexes%20characteristic%20of%20quiescence&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M004424200&volume=275&pages=38221-38229&publication_year=2000&author=Carroll%2CJS&author=Prall%2COW&author=Musgrove%2CEA&author=Sutherland%2CRL making per month?
- How much does https://doi.org/10.1016%2Fj.cell.2006.05.052 net monthly?
- How much profit is http://scholar.google.com/scholar_lookup?&title=A%20novel%20role%20for%20high-mobility%20group%20a%20proteins%20in%20cellular%20senescence%20and%20heterochromatin%20formation&journal=Cell&doi=10.1016%2Fj.cell.2006.05.052&volume=126&pages=503-514&publication_year=2006&author=Narita%2CM making per month?
- How much profit does https://citation-needed.springer.com/v2/references/10.1038/ng.730?format=refman&flavour=references generate?
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Antoni%20Hurtado
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Antoni%20Hurtado%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kelly%20A%20Holmes produce monthly?
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kelly%20A%20Holmes%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Caryn%20S%20Ross-Innes
- What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Caryn%20S%20Ross-Innes%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dominic%20Schmidt?
- Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dominic%20Schmidt%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jason%20S%20Carroll have?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jason%20S%20Carroll%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- How much revenue does https://static-content.springer.com/esm/art%3A10.1038%2Fng.730/MediaObjects/41588_2011_BFng730_MOESM16_ESM.pdf produce monthly?
- What are the total earnings of https://s100.copyright.com/AppDispatchServlet?title=FOXA1%20is%20a%20key%20determinant%20of%20estrogen%20receptor%20function%20and%20endocrine%20response&author=Antoni%20Hurtado%20et%20al&contentID=10.1038%2Fng.730©right=Springer%20Nature%20America%2C%20Inc.&publication=1061-4036&publicationDate=2010-12-12&publisherName=SpringerNature&orderBeanReset=true?
- https://citation-needed.springer.com/v2/references/10.1038/ng.730?format=refman&flavour=citation's revenue stream
- Financial intake of https://doi.org/10.1186/s13059-023-03161-y
- How much income does https://doi.org/10.1038/s41398-024-02783-5 have?
- Revenue of https://doi.org/10.1038/s41594-023-01181-7
- What is the earnings of https://doi.org/10.1186/s12610-023-00199-7?
- How much does https://doi.org/10.1186/s12885-023-11421-0 pull in?
- How much cash flow does https://www.protocols.io/ have monthly?
- Learn about the earnings of https://www.natureindex.com/
- How much does http://www.naturechina.com generate monthly?
- How much does https://www.natureasia.com/ja-jp rake in every month?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref