NATURE . COM {}

Matching Content Categories {📚}

• Education
• Science
• Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.

Keywords {🔍}

cancer, article, lung, scholar, google, cas, resistance, center, nature, egfr, university, axl, usa, kinase, erlotinib, acquired, medicine, case, research, lee, access, medical, content, mutations, tyrosine, inhibitors, york, data, cell, tumors, met, nonsmallcell, gefitinib, receptor, oncogene, tgb, department, cleveland, supplementary, cookies, zhang, authors, cancers, tumor, expression, gene, mutation, comprehensive, oncology, privacy,

Topics {✒️}

nature portfolio permissions reprints privacy policy advertising nature 471 nature small-cell lung cancer young soo park social media small-molecule kinase inhibitors oncology research se jin jang tumor cell growth egfr-mutant lung cancer mohamed abdel-rahman case genomics center dae ho lee data identify axl woo sung kim permissions tyrosine kinase inhibitors jung-shin lee springerlink instant access chang-min choi analyzed clinical data promising therapeutic target jin kyung rho governing axl expression lung cancer patients asan medical center astrocytoma cells leads stem cell traits yun jung choi ireland cancer center yale university school gefitinib-sensitizing egfr mutations egfr-targeted therapy vivo data privacy multiple anticancer therapies critical downstream target personal data jae cheol lee egfr mutant nsclc tumor-derived exosomes tumor microenvironment modulation egfr kinase domain activating erbb3 signaling comprehensive immunohistochemical study competing financial interests

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
         description:Trever Bivona and colleagues identify the upregulation of the AXL kinase in human non–small cell lung cancer with acquired resistance to erlotinib. Inhibition of AXL restores sensitivity to erlotinib in in vitro and in vivo tumor models. The authors suggest AXL as a potential therapeutic target that may prevent or overcome acquired resistance in patients with EGFR-mutant lung cancer. Human non–small cell lung cancers (NSCLCs) with activating mutations in EGFR frequently respond to treatment with EGFR-targeted tyrosine kinase inhibitors (TKIs), such as erlotinib, but responses are not durable, as tumors acquire resistance. Secondary mutations in EGFR (such as T790M) or upregulation of the MET kinase are found in over 50% of resistant tumors. Here, we report increased activation of AXL and evidence for epithelial-to-mesenchymal transition (EMT) in multiple in vitro and in vivo EGFR-mutant lung cancer models with acquired resistance to erlotinib in the absence of the EGFR p.Thr790Met alteration or MET activation. Genetic or pharmacological inhibition of AXL restored sensitivity to erlotinib in these tumor models. Increased expression of AXL and, in some cases, of its ligand GAS6 was found in EGFR-mutant lung cancers obtained from individuals with acquired resistance to TKIs. These data identify AXL as a promising therapeutic target whose inhibition could prevent or overcome acquired resistance to EGFR TKIs in individuals with EGFR-mutant lung cancer.
         datePublished:2012-07-01T00:00:00Z
         dateModified:2012-07-01T00:00:00Z
         pageStart:852
         pageEnd:860
         sameAs:https://doi.org/10.1038/ng.2330
         keywords:
            Cancer genomics
            Cancer therapeutic resistance
            Gene therapy
            Non-small-cell lung cancer
            Biomedicine
            general
            Human Genetics
            Cancer Research
            Agriculture
            Gene Function
            Animal Genetics and Genomics
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig5_HTML.jpg
         isPartOf:
            name:Nature Genetics
            issn:
               1546-1718
               1061-4036
            volumeNumber:44
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Zhenfeng Zhang
               affiliation:
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
                     name:Columbia University Medical Center
                     address:
                        name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jae Cheol Lee
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Luping Lin
               affiliation:
                     name:Helen Diller Comprehensive Cancer Center, University of California
                     address:
                        name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Victor Olivas
               affiliation:
                     name:Helen Diller Comprehensive Cancer Center, University of California
                     address:
                        name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Valerie Au
               affiliation:
                     name:Columbia University Medical Center
                     address:
                        name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Thomas LaFramboise
               affiliation:
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mohamed Abdel-Rahman
               affiliation:
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Xiaoqi Wang
               affiliation:
                     name:Columbia University Medical Center
                     address:
                        name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Alan D Levine
               affiliation:
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
                     name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                     address:
                        name:Division of Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jin Kyung Rho
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Yun Jung Choi
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chang-Min Choi
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sang-We Kim
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Se Jin Jang
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Young Soo Park
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Woo Sung Kim
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Dae Ho Lee
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jung-Shin Lee
               affiliation:
                     name:Asan Medical Center, College of Medicine, University of Ulsan
                     address:
                        name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Vincent A Miller
               affiliation:
                     name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maria Arcila
               affiliation:
                     name:Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Marc Ladanyi
               affiliation:
                     name:Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Philicia Moonsamy
               affiliation:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Charles Sawyers
               affiliation:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Titus J Boggon
               affiliation:
                     name:Yale University School of Medicine
                     address:
                        name:Department of Pharmacology, Yale University School of Medicine, New Haven, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Patrick C Ma
               affiliation:
                     name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
                     address:
                        name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Carlota Costa
               affiliation:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                     address:
                        name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Pangaea Biotech, USP Dexeus University Institute
                     address:
                        name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Miquel Taron
               affiliation:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                     address:
                        name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Pangaea Biotech, USP Dexeus University Institute
                     address:
                        name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Rafael Rosell
               affiliation:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                     address:
                        name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Pangaea Biotech, USP Dexeus University Institute
                     address:
                        name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Balazs Halmos
               affiliation:
                     name:Columbia University Medical Center
                     address:
                        name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Trever G Bivona
               affiliation:
                     name:Helen Diller Comprehensive Cancer Center, University of California
                     address:
                        name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                        type:PostalAddress
                     type:Organization
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                     address:
                        name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
      description:Trever Bivona and colleagues identify the upregulation of the AXL kinase in human non–small cell lung cancer with acquired resistance to erlotinib. Inhibition of AXL restores sensitivity to erlotinib in in vitro and in vivo tumor models. The authors suggest AXL as a potential therapeutic target that may prevent or overcome acquired resistance in patients with EGFR-mutant lung cancer. Human non–small cell lung cancers (NSCLCs) with activating mutations in EGFR frequently respond to treatment with EGFR-targeted tyrosine kinase inhibitors (TKIs), such as erlotinib, but responses are not durable, as tumors acquire resistance. Secondary mutations in EGFR (such as T790M) or upregulation of the MET kinase are found in over 50% of resistant tumors. Here, we report increased activation of AXL and evidence for epithelial-to-mesenchymal transition (EMT) in multiple in vitro and in vivo EGFR-mutant lung cancer models with acquired resistance to erlotinib in the absence of the EGFR p.Thr790Met alteration or MET activation. Genetic or pharmacological inhibition of AXL restored sensitivity to erlotinib in these tumor models. Increased expression of AXL and, in some cases, of its ligand GAS6 was found in EGFR-mutant lung cancers obtained from individuals with acquired resistance to TKIs. These data identify AXL as a promising therapeutic target whose inhibition could prevent or overcome acquired resistance to EGFR TKIs in individuals with EGFR-mutant lung cancer.
      datePublished:2012-07-01T00:00:00Z
      dateModified:2012-07-01T00:00:00Z
      pageStart:852
      pageEnd:860
      sameAs:https://doi.org/10.1038/ng.2330
      keywords:
         Cancer genomics
         Cancer therapeutic resistance
         Gene therapy
         Non-small-cell lung cancer
         Biomedicine
         general
         Human Genetics
         Cancer Research
         Agriculture
         Gene Function
         Animal Genetics and Genomics
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_Article_BFng2330_Fig5_HTML.jpg
      isPartOf:
         name:Nature Genetics
         issn:
            1546-1718
            1061-4036
         volumeNumber:44
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Zhenfeng Zhang
            affiliation:
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
                  name:Columbia University Medical Center
                  address:
                     name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jae Cheol Lee
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Luping Lin
            affiliation:
                  name:Helen Diller Comprehensive Cancer Center, University of California
                  address:
                     name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Victor Olivas
            affiliation:
                  name:Helen Diller Comprehensive Cancer Center, University of California
                  address:
                     name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Valerie Au
            affiliation:
                  name:Columbia University Medical Center
                  address:
                     name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Thomas LaFramboise
            affiliation:
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohamed Abdel-Rahman
            affiliation:
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Xiaoqi Wang
            affiliation:
                  name:Columbia University Medical Center
                  address:
                     name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alan D Levine
            affiliation:
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
                  name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
                  address:
                     name:Division of Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jin Kyung Rho
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yun Jung Choi
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chang-Min Choi
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sang-We Kim
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Se Jin Jang
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Young Soo Park
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Woo Sung Kim
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dae Ho Lee
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jung-Shin Lee
            affiliation:
                  name:Asan Medical Center, College of Medicine, University of Ulsan
                  address:
                     name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Vincent A Miller
            affiliation:
                  name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maria Arcila
            affiliation:
                  name:Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marc Ladanyi
            affiliation:
                  name:Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Philicia Moonsamy
            affiliation:
                  name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Charles Sawyers
            affiliation:
                  name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Titus J Boggon
            affiliation:
                  name:Yale University School of Medicine
                  address:
                     name:Department of Pharmacology, Yale University School of Medicine, New Haven, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Patrick C Ma
            affiliation:
                  name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
                  address:
                     name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Carlota Costa
            affiliation:
                  name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                  address:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Pangaea Biotech, USP Dexeus University Institute
                  address:
                     name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Miquel Taron
            affiliation:
                  name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                  address:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Pangaea Biotech, USP Dexeus University Institute
                  address:
                     name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rafael Rosell
            affiliation:
                  name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
                  address:
                     name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Pangaea Biotech, USP Dexeus University Institute
                  address:
                     name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Balazs Halmos
            affiliation:
                  name:Columbia University Medical Center
                  address:
                     name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Trever G Bivona
            affiliation:
                  name:Helen Diller Comprehensive Cancer Center, University of California
                  address:
                     name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
                     type:PostalAddress
                  type:Organization
                  name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
                  address:
                     name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Genetics
      issn:
         1546-1718
         1061-4036
      volumeNumber:44
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Columbia University Medical Center
      address:
         name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Helen Diller Comprehensive Cancer Center, University of California
      address:
         name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
         type:PostalAddress
      name:Helen Diller Comprehensive Cancer Center, University of California
      address:
         name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
         type:PostalAddress
      name:Columbia University Medical Center
      address:
         name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
         type:PostalAddress
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Columbia University Medical Center
      address:
         name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
         type:PostalAddress
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
      address:
         name:Division of Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Asan Medical Center, College of Medicine, University of Ulsan
      address:
         name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
         type:PostalAddress
      name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center
      address:
         name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Memorial Sloan-Kettering Cancer Center
      address:
         name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Memorial Sloan-Kettering Cancer Center
      address:
         name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
      address:
         name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
      address:
         name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
      address:
         name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
      name:Yale University School of Medicine
      address:
         name:Department of Pharmacology, Yale University School of Medicine, New Haven, USA
         type:PostalAddress
      name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
      address:
         name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
         type:PostalAddress
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
      address:
         name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
         type:PostalAddress
      name:Pangaea Biotech, USP Dexeus University Institute
      address:
         name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
         type:PostalAddress
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
      address:
         name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
         type:PostalAddress
      name:Pangaea Biotech, USP Dexeus University Institute
      address:
         name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
         type:PostalAddress
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
      address:
         name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
         type:PostalAddress
      name:Pangaea Biotech, USP Dexeus University Institute
      address:
         name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
         type:PostalAddress
      name:Columbia University Medical Center
      address:
         name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
         type:PostalAddress
      name:Helen Diller Comprehensive Cancer Center, University of California
      address:
         name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
         type:PostalAddress
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
      address:
         name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Zhenfeng Zhang
      affiliation:
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
            name:Columbia University Medical Center
            address:
               name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Jae Cheol Lee
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Luping Lin
      affiliation:
            name:Helen Diller Comprehensive Cancer Center, University of California
            address:
               name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Victor Olivas
      affiliation:
            name:Helen Diller Comprehensive Cancer Center, University of California
            address:
               name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Valerie Au
      affiliation:
            name:Columbia University Medical Center
            address:
               name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Thomas LaFramboise
      affiliation:
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
      name:Mohamed Abdel-Rahman
      affiliation:
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
      name:Xiaoqi Wang
      affiliation:
            name:Columbia University Medical Center
            address:
               name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Alan D Levine
      affiliation:
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
            name:Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center
            address:
               name:Division of Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
               type:PostalAddress
            type:Organization
      name:Jin Kyung Rho
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Yun Jung Choi
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Chang-Min Choi
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Sang-We Kim
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Se Jin Jang
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Young Soo Park
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Woo Sung Kim
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Dae Ho Lee
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Jung-Shin Lee
      affiliation:
            name:Asan Medical Center, College of Medicine, University of Ulsan
            address:
               name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
               type:PostalAddress
            type:Organization
      name:Vincent A Miller
      affiliation:
            name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center
            address:
               name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Maria Arcila
      affiliation:
            name:Memorial Sloan-Kettering Cancer Center
            address:
               name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Marc Ladanyi
      affiliation:
            name:Memorial Sloan-Kettering Cancer Center
            address:
               name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
            name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
            address:
               name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Philicia Moonsamy
      affiliation:
            name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
            address:
               name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Charles Sawyers
      affiliation:
            name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
            address:
               name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      name:Titus J Boggon
      affiliation:
            name:Yale University School of Medicine
            address:
               name:Department of Pharmacology, Yale University School of Medicine, New Haven, USA
               type:PostalAddress
            type:Organization
      name:Patrick C Ma
      affiliation:
            name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
            address:
               name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
               type:PostalAddress
            type:Organization
      name:Carlota Costa
      affiliation:
            name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
            address:
               name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Pangaea Biotech, USP Dexeus University Institute
            address:
               name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Miquel Taron
      affiliation:
            name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
            address:
               name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Pangaea Biotech, USP Dexeus University Institute
            address:
               name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Rafael Rosell
      affiliation:
            name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol
            address:
               name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Pangaea Biotech, USP Dexeus University Institute
            address:
               name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Balazs Halmos
      affiliation:
            name:Columbia University Medical Center
            address:
               name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Trever G Bivona
      affiliation:
            name:Helen Diller Comprehensive Cancer Center, University of California
            address:
               name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
            address:
               name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
      name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
      name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
      name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
      name:Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Division of Hematology/Oncology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
      name:Department of Pathology, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Division of Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, University Hospitals–Case Medical Center and Ireland Cancer Center, Case Comprehensive Cancer Center, Cleveland, USA
      name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Department of Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
      name:Thoracic Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
      name:Department of Pharmacology, Yale University School of Medicine, New Haven, USA
      name:Aerodigestive Oncology Translational Research, Translational Hematology and Oncology Research (THOR), Cleveland Clinic Taussig Cancer Institute and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
      name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
      name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
      name:Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Barcelona, Spain
      name:Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain
      name:Division of Hematology/Oncology, Columbia University Medical Center, New York, USA
      name:Division of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, USA
      name:Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/NatureGenet
• https://twitter.com/NatureGenet

External Links {🔗}(137)

• See how much https://link.springer.com/article/10.1038/ng.2330?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle makes per month
• How much profit is http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38121 making per month?
• What are the earnings of http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38310?
• https://doi.org/10.1126%2Fscience.1099314 income
• http://scholar.google.com/scholar_lookup?&title=EGFR%20mutations%20in%20lung%20cancer%3A%20correlation%20with%20clinical%20response%20to%20gefitinib%20therapy&journal=Science&doi=10.1126%2Fscience.1099314&volume=304&pages=1497-1500&publication_year=2004&author=Paez%2CJG's revenue stream
• What is the monthly revenue of https://doi.org/10.1073%2Fpnas.0405220101?
• What's http://scholar.google.com/scholar_lookup?&title=EGF%20receptor%20gene%20mutations%20are%20common%20in%20lung%20cancers%20from%20%E2%80%9Cnever%20smokers%E2%80%9D%20and%20are%20associated%20with%20sensitivity%20of%20tumors%20to%20gefitinib%20and%20erlotinib&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0405220101&volume=101&pages=13306-13311&publication_year=2004&author=Pao%2CW's gross income?
• How much revenue does https://doi.org/10.1056%2FNEJMoa040938 bring in?
• What's the income of http://scholar.google.com/scholar_lookup?&title=Activating%20mutations%20in%20the%20epidermal%20growth%20factor%20receptor%20underlying%20responsiveness%20of%20non-small-cell%20lung%20cancer%20to%20gefitinib&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMoa040938&volume=350&pages=2129-2139&publication_year=2004&author=Lynch%2CTJ?
• How much does https://doi.org/10.1126%2Fscience.1101637 rake in every month?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Gefitinib-sensitizing%20EGFR%20mutations%20in%20lung%20cancer%20activate%20anti-apoptotic%20pathways&journal=Science&doi=10.1126%2Fscience.1101637&volume=305&pages=1163-1167&publication_year=2004&author=Sordella%2CR&author=Bell%2CDW&author=Haber%2CDA&author=Settleman%2CJ
• Learn how profitable https://doi.org/10.1038%2Fnrd2871 is on a monthly basis
• http://scholar.google.com/scholar_lookup?&title=Factors%20underlying%20sensitivity%20of%20cancers%20to%20small-molecule%20kinase%20inhibitors&journal=Nat.%20Rev.%20Drug%20Discov.&doi=10.1038%2Fnrd2871&volume=8&pages=709-723&publication_year=2009&author=J%C3%A4nne%2CPA&author=Gray%2CN&author=Settleman%2CJ's financial summary
• https://doi.org/10.1056%2FNEJMe0905763 income
• How much profit does http://scholar.google.com/scholar_lookup?&title=Personalized%20medicine%20and%20inhibition%20of%20EGFR%20signaling%20in%20lung%20cancer&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMe0905763&volume=361&pages=1018-1020&publication_year=2009&author=Gazdar%2CAF generate?
• Profit of https://doi.org/10.1056%2FNEJMoa044238
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=EGFR%20mutation%20and%20resistance%20of%20non-small-cell%20lung%20cancer%20to%20gefitinib&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMoa044238&volume=352&pages=786-792&publication_year=2005&author=Kobayashi%2CS?
• What's the financial intake of https://doi.org/10.1371%2Fjournal.pmed.0020073?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Acquired%20resistance%20of%20lung%20adenocarcinomas%20to%20gefitinib%20or%20erlotinib%20is%20associated%20with%20a%20second%20mutation%20in%20the%20EGFR%20kinase%20domain&journal=PLoS%20Med.&doi=10.1371%2Fjournal.pmed.0020073&volume=2&publication_year=2005&author=Pao%2CW?
• What's the total monthly financial gain of https://doi.org/10.1126%2Fscience.1141478?
• Get to know http://scholar.google.com/scholar_lookup?&title=MET%20amplification%20leads%20to%20gefitinib%20resistance%20in%20lung%20cancer%20by%20activating%20ERBB3%20signaling&journal=Science&doi=10.1126%2Fscience.1141478&volume=316&pages=1039-1043&publication_year=2007&author=Engelman%2CJA's earnings
• What's the income generated by https://doi.org/10.1016%2Fj.ccr.2009.11.022 each month?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Preexistence%20and%20clonal%20selection%20of%20MET%20amplification%20in%20EGFR%20mutant%20NSCLC&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2009.11.022&volume=17&pages=77-88&publication_year=2010&author=Turke%2CAB have monthly?
• What's the monthly income of https://doi.org/10.1038%2Fnature09870?
• How much does http://scholar.google.com/scholar_lookup?&title=FAS%20and%20NF-%CE%BAB%20signalling%20modulate%20dependence%20of%20lung%20cancers%20on%20mutant%20EGFR&journal=Nature&doi=10.1038%2Fnature09870&volume=471&pages=523-526&publication_year=2011&author=Bivona%2CTG make?
• Income figures for https://doi.org/10.1158%2F1078-0432.CCR-10-2277
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Rebiopsy%20of%20lung%20cancer%20patients%20with%20acquired%20resistance%20to%20EGFR%20inhibitors%20and%20enhanced%20detection%20of%20the%20T790M%20mutation%20using%20a%20locked%20nucleic%20acid%E2%80%93based%20assay&journal=Clin.%20Cancer%20Res.&doi=10.1158%2F1078-0432.CCR-10-2277&volume=17&pages=1169-1180&publication_year=2011&author=Arcila%2CME?
• Income figures for https://doi.org/10.1073%2Fpnas.0710370104
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=MET%20amplification%20occurs%20with%20or%20without%20T790M%20mutations%20in%20EGFR%20mutant%20lung%20tumors%20with%20acquired%20resistance%20to%20gefitinib%20or%20erlotinib&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0710370104&volume=104&pages=20932-20937&publication_year=2007&author=Bean%2CJ?
• What's the financial intake of https://doi.org/10.1126%2Fscitranslmed.3002003?
• How much does http://scholar.google.com/scholar_lookup?&title=Genotypic%20and%20histological%20evolution%20of%20lung%20cancers%20acquiring%20resistance%20to%20EGFR%20inhibitors&journal=Sci.%20Transl.%20Med.&doi=10.1126%2Fscitranslmed.3002003&volume=3&publication_year=2011&author=Sequist%2CLV pull in monthly?
• Earnings of https://doi.org/10.1517%2F14728222.2010.515980
• How profitable is http://scholar.google.com/scholar_lookup?&title=Taking%20aim%20at%20Mer%20and%20Axl%20receptor%20tyrosine%20kinases%20as%20novel%20therapeutic%20targets%20in%20solid%20tumors&journal=Expert%20Opin.%20Ther.%20Targets&doi=10.1517%2F14728222.2010.515980&volume=14&pages=1073-1090&publication_year=2010&author=Linger%2CRM&author=Keating%2CAK&author=Earp%2CHS&author=Graham%2CDK?
• How much cash flow does https://doi.org/10.1158%2F1535-7163.MCT-09-0707 have monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20Mer%20and%20Axl%20receptor%20tyrosine%20kinases%20in%20astrocytoma%20cells%20leads%20to%20increased%20apoptosis%20and%20improved%20chemosensitivity&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-09-0707&volume=9&pages=1298-1307&publication_year=2010&author=Keating%2CAK generate monthly?
• Learn about the earnings of https://doi.org/10.1038%2Fonc.2010.509
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Vimentin%20regulates%20EMT%20induction%20by%20Slug%20and%20oncogenic%20H-Ras%20and%20migration%20by%20governing%20Axl%20expression%20in%20breast%20cancer&journal=Oncogene&doi=10.1038%2Fonc.2010.509&volume=30&pages=1436-1448&publication_year=2011&author=Vuoriluoto%2CK
• How much profit does https://doi.org/10.1097%2FJTO.0b013e318216ee52 make?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Epithelial%20to%20mesenchymal%20transition%20in%20an%20epidermal%20growth%20factor%20receptor%E2%80%93mutant%20lung%20cancer%20cell%20line%20with%20acquired%20resistance%20to%20erlotinib&journal=J.%20Thorac.%20Oncol.&doi=10.1097%2FJTO.0b013e318216ee52&volume=6&pages=1152-1161&publication_year=2011&author=Suda%2CK
• What's the total monthly financial gain of https://doi.org/10.1038%2Fonc.2010.268?
• See how much http://scholar.google.com/scholar_lookup?&title=An%20anti-Axl%20monoclonal%20antibody%20attenuates%20xenograft%20tumor%20growth%20and%20enhances%20the%20effect%20of%20multiple%20anticancer%20therapies&journal=Oncogene&doi=10.1038%2Fonc.2010.268&volume=29&pages=5254-5264&publication_year=2010&author=Ye%2CX makes per month
• Income figures for https://doi.org/10.1158%2F0008-5472.CAN-08-4889
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20tumor%20cell%20growth%2C%20invasion%2C%20and%20metastasis%20by%20EXEL-2880%20%28XL880%2C%20GSK1363089%29%2C%20a%20novel%20inhibitor%20of%20HGF%20and%20VEGF%20receptor%20tyrosine%20kinases&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-08-4889&volume=69&pages=8009-8016&publication_year=2009&author=Qian%2CF generate?
• What's the financial intake of https://doi.org/10.1073%2Fpnas.0709662105?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20T790M%20mutation%20in%20EGFR%20kinase%20causes%20drug%20resistance%20by%20increasing%20the%20affinity%20for%20ATP&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0709662105&volume=105&pages=2070-2075&publication_year=2008&author=Yun%2CCH bring in each month?
• What's the profit of https://doi.org/10.1038%2Fnrc2620?
• How much does http://scholar.google.com/scholar_lookup?&title=Transitions%20between%20epithelial%20and%20mesenchymal%20states%3A%20acquisition%20of%20malignant%20and%20stem%20cell%20traits&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc2620&volume=9&pages=265-273&publication_year=2009&author=Polyak%2CK&author=Weinberg%2CRA gross monthly?
• What's the financial outcome of https://doi.org/10.1200%2FJCO.2009.24.7049?
• How much does http://scholar.google.com/scholar_lookup?&title=Clinical%20definition%20of%20acquired%20resistance%20to%20epidermal%20growth%20factor%20receptor%20tyrosine%20kinase%20inhibitors%20in%20non-small-cell%20lung%20cancer&journal=J.%20Clin.%20Oncol.&doi=10.1200%2FJCO.2009.24.7049&volume=28&pages=357-360&publication_year=2010&author=Jackman%2CD gross monthly?
• Revenue of https://doi.org/10.1038%2Fsj.onc.1201865
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Determinants%20for%20transformation%20induced%20by%20the%20Axl%20receptor%20tyrosine%20kinase&journal=Oncogene&doi=10.1038%2Fsj.onc.1201865&volume=16&pages=3177-3187&publication_year=1998&author=Burchert%2CA&author=Attar%2CEC&author=McCloskey%2CP&author=Fridell%2CYW&author=Liu%2CET
• What's the income of https://doi.org/10.1038%2Fonc.2008.57?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Axl%20promotes%20cell%20invasion%20by%20inducing%20MMP-9%20activity%20through%20activation%20of%20NF-%CE%BAB%20and%20Brg-1&journal=Oncogene&doi=10.1038%2Fonc.2008.57&volume=27&pages=4044-4055&publication_year=2008&author=Tai%2CKY&author=Shieh%2CYS&author=Lee%2CCS&author=Shiah%2CSG&author=Wu%2CCW making per month?
• See how much https://doi.org/10.1093%2Fajcp%2F88.3.286 makes per month
• http://scholar.google.com/scholar_lookup?&title=The%20distribution%20of%20vimentin%20and%20keratin%20in%20epithelial%20and%20nonepithelial%20neoplasms.%20A%20comprehensive%20immunohistochemical%20study%20on%20formalin-%20and%20alcohol-fixed%20tumors&journal=Am.%20J.%20Clin.%20Pathol.&doi=10.1093%2Fajcp%2F88.3.286&volume=88&pages=286-296&publication_year=1987&author=Azumi%2CN&author=Battifora%2CH's total income per month
• How much profit does https://doi.org/10.1038%2Fonc.2009.135 generate?
• Find out how much http://scholar.google.com/scholar_lookup?&title=An%20integrated%20genomic%20analysis%20of%20lung%20cancer%20reveals%20loss%20of%20DUSP4%20in%20EGFR-mutant%20tumors&journal=Oncogene&doi=10.1038%2Fonc.2009.135&volume=28&pages=2773-2783&publication_year=2009&author=Chitale%2CD earns monthly
• How much profit is https://doi.org/10.3816%2FCLC.2009.n.001 making per month?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Circulating%20microRNA%20signatures%20of%20tumor-derived%20exosomes%20for%20early%20diagnosis%20of%20non-small-cell%20lung%20cancer&journal=Clin.%20Lung%20Cancer&doi=10.3816%2FCLC.2009.n.001&volume=10&pages=8-9&publication_year=2009&author=Rosell%2CR&author=Wei%2CJ&author=Taron%2CM
• What's the monthly income of https://doi.org/10.2353%2Fjmoldx.2010.090140?
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Assessment%20of%20EGFR%20mutation%20status%20in%20lung%20adenocarcinoma%20by%20immunohistochemistry%20using%20antibodies%20specific%20to%20the%20two%20major%20forms%20of%20mutant%20EGFR&journal=J.%20Mol.%20Diagn.&doi=10.2353%2Fjmoldx.2010.090140&volume=12&pages=169-176&publication_year=2010&author=Brevet%2CM&author=Arcila%2CM&author=Ladanyi%2CM
• How much does https://citation-needed.springer.com/v2/references/10.1038/ng.2330?format=refman&flavour=references generate monthly?
• What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Zhenfeng%20Zhang?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Zhenfeng%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jae%20Cheol%20Lee generate?
• Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jae%20Cheol%20Lee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Luping%20Lin each month?
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Luping%20Lin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Victor%20Olivas each month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Victor%20Olivas%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Valerie%20Au bring in?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Valerie%20Au%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Thomas%20LaFramboise making per month?
• Monthly income for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Thomas%20LaFramboise%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mohamed%20Abdel-Rahman income
• Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mohamed%20Abdel-Rahman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xiaoqi%20Wang?
• Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xiaoqi%20Wang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alan%20D%20Levine?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alan%20D%20Levine%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jin%20Kyung%20Rho generate monthly?
• How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jin%20Kyung%20Rho%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
• What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yun%20Jung%20Choi?
• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yun%20Jung%20Choi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Chang-Min%20Choi making per month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Chang-Min%20Choi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sang-We%20Kim's total income per month
• What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sang-We%20Kim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Se%20Jin%20Jang
• What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Se%20Jin%20Jang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Young%20Soo%20Park
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Young%20Soo%20Park%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Woo%20Sung%20Kim generate monthly?
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Woo%20Sung%20Kim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dae%20Ho%20Lee is on a monthly basis
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dae%20Ho%20Lee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jung-Shin%20Lee?
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jung-Shin%20Lee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Vincent%20A%20Miller?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Vincent%20A%20Miller%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maria%20Arcila net monthly?
• How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maria%20Arcila%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Marc%20Ladanyi?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marc%20Ladanyi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Philicia%20Moonsamy's revenue stream
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Philicia%20Moonsamy%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• See how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Charles%20Sawyers makes per month
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Charles%20Sawyers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Titus%20J%20Boggon make?
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Titus%20J%20Boggon%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Patrick%20C%20Ma?
• What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Patrick%20C%20Ma%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carlota%20Costa generate monthly?
• What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carlota%20Costa%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Miquel%20Taron
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Miquel%20Taron%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rafael%20Rosell?
• What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rafael%20Rosell%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Balazs%20Halmos rake in every month?
• What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Balazs%20Halmos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Trever%20G%20Bivona's earnings
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Trever%20G%20Bivona%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How profitable is https://static-content.springer.com/esm/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_BFng2330_MOESM47_ESM.pdf?
• https://static-content.springer.com/esm/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_BFng2330_MOESM48_ESM.xls's total income per month
• How much money does https://static-content.springer.com/esm/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_BFng2330_MOESM49_ESM.xls make?
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fng.2330/MediaObjects/41588_2012_BFng2330_MOESM50_ESM.xls rake in every month?
• What is the monthly revenue of https://s100.copyright.com/AppDispatchServlet?title=Activation%20of%20the%20AXL%20kinase%20causes%20resistance%20to%20EGFR-targeted%20therapy%20in%20lung%20cancer&author=Zhenfeng%20Zhang%20et%20al&contentID=10.1038%2Fng.2330©right=Springer%20Nature%20America%2C%20Inc.&publication=1061-4036&publicationDate=2012-07-01&publisherName=SpringerNature&orderBeanReset=true?
• What are the total earnings of https://citation-needed.springer.com/v2/references/10.1038/ng.2330?format=refman&flavour=citation?
• https://doi.org/10.1186/s40364-023-00545-x's financial summary
• Explore the financials of https://doi.org/10.1038/s41388-024-02987-5
• Check the income stats for https://doi.org/10.1186/s13046-023-02726-w
• Find out how much https://doi.org/10.1186/s40360-023-00661-2 earns monthly
• Find out how much https://doi.org/10.1186/s12931-023-02329-1 earns monthly
• Get to know what's the income of https://www.protocols.io/
• What's the financial gain of https://www.natureindex.com/?
• Discover the revenue of http://www.naturechina.com
• Earnings of https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref