
NATURE . COM {
}
Title:
The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3 | Nature Communications
Description:
The NLRP3 inflammasome has a fundamental role in host defence against microbial pathogens and its deregulation may cause diverse inflammatory diseases. NLRP3 protein expression is a rate-limiting step for inflammasome activation, thus its expression must be tightly controlled to maintain immune homeostasis and avoid detrimental effects. However, how NLRP3 expression is regulated remains largely unknown. In this study, we identify E3 ubiquitin ligase TRIM31 as a feedback suppressor of NLRP3 inflammasome. TRIM31 directly binds to NLRP3, promotes K48-linked polyubiquitination and proteasomal degradation of NLRP3. Consequently, TRIM31 deficiency enhances NLRP3 inflammasome activation and aggravates alum-induced peritonitis in vivo. Furthermore, TRIM31 deficiency attenuates the severity of dextran sodium sulfate (DSS)-induced colitis, an inflammatory bowel diseases model in which NLRP3 possesses protective roles. Thus, our research describes a mechanism by which TRIM31 limits NLRP3 inflammasome activity under physiological conditions and suggests TRIM31 as a potential therapeutic target for the intervention of NLRP3 inflammasome related diseases. The NLRP3 inflammasome controls the response of the host to pathogens; precise regulation is required to limit autoimmune diseases. Here, the authors identify the E3 ligase TRIM31 that aids the ubiquitin-mediated proteasomal degradation of NLRP3, which may be a therapeutic target for alleviating disease.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Video & Online Content
- DIY & Home Improvement
- Education
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.
Keywords {🔍}
trim, nlrp, inflammasome, fig, expression, article, activation, macrophages, cells, google, scholar, analysis, degradation, mice, cas, ilβ, protein, deficiency, mouse, lps, immunoblot, ubiquitin, peritoneal, ubiquitination, data, immune, nature, colitis, activity, supplementary, cell, ligase, klinked, caspase, hekt, transfected, proteasomal, experiments, inflammatory, diseases, effects, regulation, tnfα, thp, model, atp, pathway, secretion, extracts, colon,
Topics {✒️}
nature portfolio privacy policy il-1β-triggered nf-κb activation advertising n-terminal ring-finger domain research identify trim31 c-terminal coiled-coil domain pro-interleukin-1β protein complexes anti-il-1β p31&p17 nature 481 nature social media ros/mapk/nf-κb signaling elisa kits ha-tagged k48-linked ubiquitin scientific investigation board c-terminal coiled-coil nf-κb reporter plasmid 0/ reprints key research ha-tagged k63-linked ubiquitin dextran sodium sulfate dextran sulfate sodium japan aggravates alum-induced peritonitis research describes n-terminal ring domain full size image enhanced il-1β secretion tnf-α-induced nlrp3 expression dss-induced mucosal damage e3 ligase activity promotes k48-linked polyubiquitination sds–polyacrylamide gel electrophoresis exacerbated dss-induced colitis aggravated alum-induced peritonitis k48-linked polyubiquitination leads il-1β secretion stimulated subsequent il-1β secretion agonists-induced nlrp3 expression acute dss-induced colitis nfκb-mediated signaling pathway trim31-mediated nlrp3 polyubiquitination aryl hydrocarbon receptor dds-induced colitis model research promotes k48-linked ubiquitination mediating lysosome-dependent degradation wnt/β-catenin pathway dss-induced colitis model
Questions {❓}
- A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?
Schema {🗺️}
WebPage:
mainEntity:
headline:The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3
description:The NLRP3 inflammasome has a fundamental role in host defence against microbial pathogens and its deregulation may cause diverse inflammatory diseases. NLRP3 protein expression is a rate-limiting step for inflammasome activation, thus its expression must be tightly controlled to maintain immune homeostasis and avoid detrimental effects. However, how NLRP3 expression is regulated remains largely unknown. In this study, we identify E3 ubiquitin ligase TRIM31 as a feedback suppressor of NLRP3 inflammasome. TRIM31 directly binds to NLRP3, promotes K48-linked polyubiquitination and proteasomal degradation of NLRP3. Consequently, TRIM31 deficiency enhances NLRP3 inflammasome activation and aggravates alum-induced peritonitis in vivo. Furthermore, TRIM31 deficiency attenuates the severity of dextran sodium sulfate (DSS)-induced colitis, an inflammatory bowel diseases model in which NLRP3 possesses protective roles. Thus, our research describes a mechanism by which TRIM31 limits NLRP3 inflammasome activity under physiological conditions and suggests TRIM31 as a potential therapeutic target for the intervention of NLRP3 inflammasome related diseases. The NLRP3 inflammasome controls the response of the host to pathogens; precise regulation is required to limit autoimmune diseases. Here, the authors identify the E3 ligase TRIM31 that aids the ubiquitin-mediated proteasomal degradation of NLRP3, which may be a therapeutic target for alleviating disease.
datePublished:2016-12-08T00:00:00Z
dateModified:2016-12-08T00:00:00Z
pageStart:1
pageEnd:11
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/ncomms13727
keywords:
Interleukins
NOD-like receptors
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig7_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig8_HTML.jpg
isPartOf:
name:Nature Communications
issn:
2041-1723
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Hui Song
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Bingyu Liu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Wanwan Huai
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Zhongxia Yu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Wenwen Wang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Jing Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Lihui Han
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Guosheng Jiang
affiliation:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences
address:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Lining Zhang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Chengjiang Gao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Wei Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3
description:The NLRP3 inflammasome has a fundamental role in host defence against microbial pathogens and its deregulation may cause diverse inflammatory diseases. NLRP3 protein expression is a rate-limiting step for inflammasome activation, thus its expression must be tightly controlled to maintain immune homeostasis and avoid detrimental effects. However, how NLRP3 expression is regulated remains largely unknown. In this study, we identify E3 ubiquitin ligase TRIM31 as a feedback suppressor of NLRP3 inflammasome. TRIM31 directly binds to NLRP3, promotes K48-linked polyubiquitination and proteasomal degradation of NLRP3. Consequently, TRIM31 deficiency enhances NLRP3 inflammasome activation and aggravates alum-induced peritonitis in vivo. Furthermore, TRIM31 deficiency attenuates the severity of dextran sodium sulfate (DSS)-induced colitis, an inflammatory bowel diseases model in which NLRP3 possesses protective roles. Thus, our research describes a mechanism by which TRIM31 limits NLRP3 inflammasome activity under physiological conditions and suggests TRIM31 as a potential therapeutic target for the intervention of NLRP3 inflammasome related diseases. The NLRP3 inflammasome controls the response of the host to pathogens; precise regulation is required to limit autoimmune diseases. Here, the authors identify the E3 ligase TRIM31 that aids the ubiquitin-mediated proteasomal degradation of NLRP3, which may be a therapeutic target for alleviating disease.
datePublished:2016-12-08T00:00:00Z
dateModified:2016-12-08T00:00:00Z
pageStart:1
pageEnd:11
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/ncomms13727
keywords:
Interleukins
NOD-like receptors
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig7_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_Article_BFncomms13727_Fig8_HTML.jpg
isPartOf:
name:Nature Communications
issn:
2041-1723
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Hui Song
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Bingyu Liu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Wanwan Huai
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Zhongxia Yu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Wenwen Wang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Jing Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Lihui Han
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Guosheng Jiang
affiliation:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences
address:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Lining Zhang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
type:Person
name:Chengjiang Gao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Wei Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Nature Communications
issn:
2041-1723
volumeNumber:7
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences
address:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Hui Song
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Bingyu Liu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Wanwan Huai
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Zhongxia Yu
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Wenwen Wang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Jing Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Lihui Han
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Guosheng Jiang
affiliation:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences
address:
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China
type:PostalAddress
type:Organization
name:Lining Zhang
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Chengjiang Gao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
name:Wei Zhao
affiliation:
name:Shandong University School of Medicine
address:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine
address:
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
name:Department of Immunology, Shandong University School of Medicine, Jinan, China
name:Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Medicine, Jinan, China
Social Networks {👍}(2)
External Links {🔗}(127)
- Learn about the earnings of https://doi.org/10.1016%2Fj.cell.2010.01.040
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=The%20inflammasomes&journal=Cell&doi=10.1016%2Fj.cell.2010.01.040&volume=140&pages=821-832&publication_year=2010&author=Schroder%2CK&author=Tschopp%2CJ is on a monthly basis
- What are the total earnings of https://doi.org/10.1146%2Fannurev-immunol-031210-101405?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=The%20inflammasome%20NLRs%20in%20immunity%2C%20inflammation%2C%20and%20associated%20diseases&journal=Annu.%20Rev.%20Immunol.&doi=10.1146%2Fannurev-immunol-031210-101405&volume=29&pages=707-735&publication_year=2011&author=Davis%2CBK&author=Wen%2CH&author=Ting%2CJP
- How much cash flow does https://doi.org/10.1038%2Fni.2237 have monthly?
- http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20inflammasome%20signaling&journal=Nat.%20Immunol.&doi=10.1038%2Fni.2237&volume=13&pages=333-342&publication_year=2012&author=Rathinam%2CVA&author=Vanaja%2CSK&author=Fitzgerald%2CKA's revenue stream
- What are the total earnings of https://doi.org/10.1038%2Fnri3452?
- How much does http://scholar.google.com/scholar_lookup?&title=Activation%20and%20regulation%20of%20the%20inflammasomes&journal=Nat.%20Rev.%20Immunol.&doi=10.1038%2Fnri3452&volume=13&pages=397-411&publication_year=2013&author=Latz%2CE&author=Xiao%2CTS&author=Stutz%2CA rake in every month?
- Find out how much https://doi.org/10.1038%2Fnm.3893 earns monthly
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Inflammasomes%3A%20mechanism%20of%20action%2C%20role%20in%20disease%2C%20and%20therapeutics&journal=Nat.%20Med.&doi=10.1038%2Fnm.3893&volume=21&pages=677-687&publication_year=2015&author=Guo%2CH&author=Callaway%2CJB&author=Ting%2CJP?
- What's the total monthly financial gain of https://doi.org/10.1038%2Fnature10759?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2012Natur.481..278S gross monthly?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Inflammasomes%20in%20health%20and%20disease&journal=Nature&doi=10.1038%2Fnature10759&volume=481&pages=278-286&publication_year=2012&author=Strowig%2CT&author=Henao-Mejia%2CJ&author=Elinav%2CE&author=Flavell%2CR have monthly?
- How much does https://doi.org/10.1038%2Fni.2228 net monthly?
- Income figures for http://scholar.google.com/scholar_lookup?&title=A%20role%20for%20the%20NLRP3%20inflammasome%20in%20metabolic%20diseases--did%20Warburg%20miss%20inflammation%3F&journal=Nat.%20Immunol.&doi=10.1038%2Fni.2228&volume=13&pages=352-357&publication_year=2012&author=Wen%2CH&author=Ting%2CJP&author=O%27Neill%2CLA
- Profit of https://doi.org/10.14348%2Fmolcells.2014.0104
- How much does http://scholar.google.com/scholar_lookup?&title=Inflammasomes%3A%20molecular%20regulation%20and%20implications%20for%20metabolic%20and%20cognitive%20diseases&journal=Mol.%20Cells&doi=10.14348%2Fmolcells.2014.0104&volume=37&pages=441-448&publication_year=2014&author=Choi%2CAJ&author=Ryter%2CSW pull in monthly?
- Financial intake of https://doi.org/10.1146%2Fannurev-pathol-012414-040431
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=The%20inflammasomes%20and%20autoinflammatory%20syndromes&journal=Annu.%20Rev.%20Pathol.&doi=10.1146%2Fannurev-pathol-012414-040431&volume=10&pages=395-424&publication_year=2015&author=Broderick%2CL
- How much does https://doi.org/10.3109%2F10409238.2012.694844 earn?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Biochemical%20regulation%20of%20the%20inflammasome&journal=Crit.%20Rev.%20Biochem.%20Mol.%20Biol.&doi=10.3109%2F10409238.2012.694844&volume=47&pages=424-443&publication_year=2012&author=Dowling%2CJK&author=O%27Neill%2CLA
- Revenue of https://doi.org/10.1016%2Fj.coi.2012.12.004
- Income figures for http://scholar.google.com/scholar_lookup?&title=Modulatory%20mechanisms%20controlling%20the%20NLRP3%20inflammasome%20in%20inflammation%3A%20recent%20developments&journal=Curr.%20Opin.%20Immunol.&doi=10.1016%2Fj.coi.2012.12.004&volume=25&pages=40-45&publication_year=2013&author=Haneklaus%2CM&author=O%27Neill%2CLA&author=Coll%2CRC
- Earnings of https://doi.org/10.4049%2Fjimmunol.0901363
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Cutting%20edge%3A%20NF-kappaB%20activating%20pattern%20recognition%20and%20cytokine%20receptors%20license%20NLRP3%20inflammasome%20activation%20by%20regulating%20NLRP3%20expression&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.0901363&volume=183&pages=787-791&publication_year=2009&author=Bauernfeind%2CFG?
- Income figures for https://doi.org/10.1074%2Fjbc.M112.407130
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Non-transcriptional%20priming%20and%20deubiquitination%20regulate%20NLRP3%20inflammasome%20activation&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M112.407130&volume=287&pages=36617-36622&publication_year=2012&author=Juliana%2CC
- How much does https://doi.org/10.1038%2Fncomms5738 earn?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Aryl%20hydrocarbon%20receptor%20negatively%20regulates%20NLRP3%20inflammasome%20activity%20by%20inhibiting%20NLRP3%20transcription&journal=Nat.%20Commun.&doi=10.1038%2Fncomms5738&volume=5&publication_year=2014&author=Huai%2CW
- What is the monthly revenue of https://doi.org/10.4049%2Fjimmunol.1201516?
- Income figures for http://scholar.google.com/scholar_lookup?&title=NLRP3%20inflammasome%20activity%20is%20negatively%20controlled%20by%20miR-223&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.1201516&volume=189&pages=4175-4181&publication_year=2012&author=Bauernfeind%2CF
- How much does https://doi.org/10.4049%2Fjimmunol.1200312 earn?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Cutting%20edge%3A%20miR-223%20and%20EBV%20miR-BART15%20regulate%20the%20NLRP3%20inflammasome%20and%20IL-1%CE%B2%20production&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.1200312&volume=189&pages=3795-3799&publication_year=2012&author=Haneklaus%2CM?
- Discover the revenue of https://doi.org/10.1073%2Fpnas.1306556110
- How much profit does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2013PNAS..11016079C make?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=TLR-induced%20PAI-2%20expression%20suppresses%20IL-1%CE%B2%20processing%20via%20increasing%20autophagy%20and%20NLRP3%20degradation&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.1306556110&volume=110&pages=16079-16084&publication_year=2013&author=Chuang%2CSY?
- Check the income stats for https://doi.org/10.1016%2Fj.cell.2014.11.047
- What's the income of http://scholar.google.com/scholar_lookup?&title=Dopamine%20controls%20systemic%20inflammation%20through%20inhibition%20of%20NLRP3%20inflammasome&journal=Cell&doi=10.1016%2Fj.cell.2014.11.047&volume=160&pages=62-73&publication_year=2015&author=Yan%2CY?
- Earnings of https://doi.org/10.1016%2Fj.cytogfr.2014.08.001
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=InTRIMsic%20immunity%3A%20positive%20and%20negative%20regulation%20of%20immune%20signaling%20by%20tripartite%20motif%20proteins&journal=Cytokine%20Growth%20Factor%20Rev.&doi=10.1016%2Fj.cytogfr.2014.08.001&volume=25&pages=563-576&publication_year=2014&author=Versteeg%2CGA&author=Benke%2CS&author=Garc%C3%ADa-Sastre%2CA&author=Rajsbaum%2CR
- Earnings of https://doi.org/10.1034%2Fj.1399-0039.2003.610105.x
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Cluster%20of%20TRIM%20genes%20in%20the%20human%20MHC%20class%20I%20region%20sharing%20the%20B30.2%20domain&journal=Tissue%20Antigens&doi=10.1034%2Fj.1399-0039.2003.610105.x&volume=61&pages=63-71&publication_year=2003&author=Meyer%2CM&author=Gaudieri%2CS&author=Rhodes%2CDA&author=Trowsdale%2CJ?
- What are the earnings of https://doi.org/10.1128%2FJVI.01804-12?
- How profitable is http://scholar.google.com/scholar_lookup?&title=TRIM%20protein-mediated%20regulation%20of%20inflammatory%20and%20innate%20immune%20signaling%20and%20its%20association%20with%20antiretroviral%20activity&journal=J.%20Virol.&doi=10.1128%2FJVI.01804-12&volume=87&pages=257-272&publication_year=2013&author=Uchil%2CPD?
- What are the earnings of https://doi.org/10.1371%2Fjournal.ppat.1004726?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=TRIM26%20negatively%20regulates%20interferon-%CE%B2%20production%20and%20antiviral%20response%20through%20polyubiquitination%20and%20degradation%20of%20nuclear%20IRF3&journal=PLoS%20Pathog.&doi=10.1371%2Fjournal.ppat.1004726&volume=11&publication_year=2015&author=Wang%2CP&author=Zhao%2CW&author=Zhao%2CK&author=Zhang%2CL&author=Gao%2CC?
- What is the monthly revenue of https://link.springer.com/doi/10.1007/s00018-015-2040-x?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=TRIM39%20negatively%20regulates%20the%20NF%CE%BAB-mediated%20signaling%20pathway%20through%20stabilization%20of%20cactin&journal=Cell%20Mol.%20Life%20Sci.&doi=10.1007%2Fs00018-015-2040-x&volume=73&pages=1085-1101&publication_year=2016&author=Suzuki%2CM?
- Monthly income for https://doi.org/10.4049%2Fjimmunol.1103255
- How much profit does http://scholar.google.com/scholar_lookup?&title=E3%20ubiquitin%20ligase%20tripartite%20motif%2038%20negatively%20regulates%20TLR-mediated%20immune%20responses%20by%20proteasomal%20degradation%20of%20TNF%20receptor-associated%20factor%206%20in%20macrophages&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.1103255&volume=188&pages=2567-2574&publication_year=2012&author=Zhao%2CW&author=Wang%2CL&author=Zhang%2CM&author=Yuan%2CC&author=Gao%2CC generate?
- How much revenue does https://doi.org/10.1073%2Fpnas.1318227111 produce monthly?
- What's the profit of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2014PNAS..111.1509H?
- How much does http://scholar.google.com/scholar_lookup?&title=TRIM38%20inhibits%20TNF%CE%B1-%20and%20IL-1%CE%B2-triggered%20NF-%CE%BAB%20activation%20by%20mediating%20lysosome-dependent%20degradation%20of%20TAB2%2F3&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.1318227111&volume=111&pages=1509-1514&publication_year=2014&author=Hu%2CMM pull in monthly?
- How much revenue does https://doi.org/10.1073%2Fpnas.1111233109 generate?
- What's the income generated by http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2011PNAS..10820072C each month?
- Get to know http://scholar.google.com/scholar_lookup?&title=Tripartite%20motif%20containing%20protein%2027%20negatively%20regulates%20CD4%20T%20cells%20by%20ubiquitinating%20and%20inhibiting%20the%20class%20II%20PI3K-C2%CE%B2&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.1111233109&volume=108&pages=20072-20077&publication_year=2011&author=Cai%2CX's earnings
- How profitable is https://doi.org/10.1038%2Fcr.2015.108?
- How much money does http://scholar.google.com/scholar_lookup?&title=Siglec1%20suppresses%20antiviral%20innate%20immune%20response%20by%20inducing%20TBK1%20degradation%20via%20the%20ubiquitin%20ligase%20TRIM27&journal=Cell%20Res.&doi=10.1038%2Fcr.2015.108&volume=25&pages=1121-1136&publication_year=2015&author=Zheng%2CQ make?
- How much revenue does https://doi.org/10.1038%2Fnri3111 produce monthly?
- See how much http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20ubiquitylation%20in%20immune%20defence%20and%20pathogen%20evasion&journal=Nat.%20Rev.%20Immunol.&doi=10.1038%2Fnri3111&volume=12&pages=35-48&publication_year=2011&author=Jiang%2CX&author=Chen%2CZJ makes per month
- Learn about the earnings of https://doi.org/10.4049%2Fjimmunol.1202737
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=TLR%20agonists%20stimulate%20Nlrp3-dependent%20IL-1%CE%B2%20production%20independently%20of%20the%20purinergic%20P2X7%20receptor%20in%20dendritic%20cells%20and%20in%20vivo&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.1202737&volume=190&pages=334-339&publication_year=2013&author=He%2CY&author=Franchi%2CL&author=N%C3%BA%C3%B1ez%2CG
- How much money does https://doi.org/10.1038%2Fnm.3806 make?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=A%20small-molecule%20inhibitor%20of%20the%20NLRP3%20inflammasome%20for%20the%20treatment%20of%20inflammatory%20diseases&journal=Nat.%20Med.&doi=10.1038%2Fnm.3806&volume=21&pages=248-255&publication_year=2015&author=Coll%2CRC
- How much income does https://doi.org/10.1016%2Fj.immuni.2011.02.006 have?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Type%20I%20interferon%20inhibits%20interleukin-1%20production%20and%20inflammasome%20activation&journal=Immunity&doi=10.1016%2Fj.immuni.2011.02.006&volume=34&pages=213-223&publication_year=2011&author=Guarda%2CG generate?
- Profit of https://doi.org/10.1038%2Fnprot.2007.41
- What's the income of http://scholar.google.com/scholar_lookup?&title=Chemically%20induced%20mouse%20models%20of%20intestinal%20inflammation&journal=Nat.%20Protoc.&doi=10.1038%2Fnprot.2007.41&volume=2&pages=541-546&publication_year=2007&author=Wirtz%2CS&author=Neufert%2CC&author=Weigmann%2CB&author=Neurath%2CMF?
- How much money does https://doi.org/10.1016%2Fj.immuni.2010.03.003 generate?
- http://scholar.google.com/scholar_lookup?&title=The%20NLRP3%20inflammasome%20protects%20against%20loss%20of%20epithelial%20integrity%20and%20mortality%20during%20experimental%20colitis&journal=Immunity&doi=10.1016%2Fj.immuni.2010.03.003&volume=32&pages=379-391&publication_year=2010&author=Zaki%2CMH's financial summary
- https://doi.org/10.1038%2Fni.2215 income
- How much does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20autophagy%20by%20inflammatory%20signals%20limits%20IL-1%CE%B2%20production%20by%20targeting%20ubiquitinated%20inflammasomes%20for%20destruction&journal=Nat.%20Immunol.&doi=10.1038%2Fni.2215&volume=13&pages=255-263&publication_year=2012&author=Shi%2CCS net monthly?
- What's the monthly money flow for https://doi.org/10.1016%2Fj.immuni.2012.01.009?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Oxidized%20mitochondrial%20DNA%20activates%20the%20NLRP3%20inflammasome%20during%20apoptosis&journal=Immunity&doi=10.1016%2Fj.immuni.2012.01.009&volume=36&pages=401-414&publication_year=2012&author=Shimada%2CK?
- Get to know https://doi.org/10.1084%2Fjem.20132486's earnings
- How much does http://scholar.google.com/scholar_lookup?&title=The%20linear%20ubiquitin%20assembly%20complex%20%28LUBAC%29%20is%20essential%20for%20NLRP3%20inflammasome%20activation&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20132486&volume=211&pages=1333-1347&publication_year=2014&author=Rodgers%2CMA rake in every month?
- What's the income of https://doi.org/10.1016%2Fj.immuni.2014.12.031?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=A20%20restricts%20ubiquitination%20of%20pro-interleukin-1%CE%B2%20protein%20complexes%20and%20suppresses%20NLRP3%20inflammasome%20activity&journal=Immunity&doi=10.1016%2Fj.immuni.2014.12.031&volume=42&pages=55-67&publication_year=2015&author=Duong%2CBH each month?
- How much income does https://doi.org/10.4049%2Fjimmunol.1401448 have?
- http://scholar.google.com/scholar_lookup?&title=The%20E3%20ubiquitin%20ligase%20tripartite%20motif%2033%20is%20essential%20for%20cytosolic%20RNA-induced%20NLRP3%20inflammasome%20activation&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.1401448&volume=193&pages=3676-3682&publication_year=2014&author=Weng%2CL's total income per month
- Get to know what's the income of https://doi.org/10.1074%2Fjbc.M112.422238
- How much profit does http://scholar.google.com/scholar_lookup?&title=Deubiquitinases%20regulate%20the%20activity%20of%20caspase-1%20and%20interleukin-1%CE%B2%20secretion%20via%20assembly%20of%20the%20inflammasome&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M112.422238&volume=288&pages=2721-2733&publication_year=2013&author=Lopez-Castejon%2CG make?
- What's https://doi.org/10.1016%2Fj.molcel.2012.11.009's gross income?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Deubiquitination%20of%20NLRP3%20by%20BRCC3%20critically%20regulates%20inflammasome%20activity&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2012.11.009&volume=49&pages=331-338&publication_year=2013&author=Py%2CBF&author=Kim%2CMS&author=Vakifahmetoglu-Norberg%2CH&author=Yuan%2CJ?
- What's https://doi.org/10.1084%2Fjem.20100050's gross income?
- See how much http://scholar.google.com/scholar_lookup?&title=The%20NLRP3%20inflammasome%20functions%20as%20a%20negative%20regulator%20of%20tumorigenesis%20during%20colitis-associated%20cancer&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20100050&volume=207&pages=1045-1056&publication_year=2010&author=Allen%2CIC makes per month
- Find out how much https://doi.org/10.1002%2Fibd.21478 earns monthly
- How much profit is http://scholar.google.com/scholar_lookup?&title=NLRP3%20inflammasome%20plays%20a%20key%20role%20in%20the%20regulation%20of%20intestinal%20homeostasis&journal=Inflamm.%20Bowel%20Dis.&doi=10.1002%2Fibd.21478&volume=17&pages=1359-1372&publication_year=2011&author=Hirota%2CSA making per month?
- Check the income stats for https://doi.org/10.1084%2Fjem.20120024
- How much does http://scholar.google.com/scholar_lookup?&title=TRAF-interacting%20protein%20%28TRIP%29%20negatively%20regulates%20IFN-%CE%B2%20production%20and%20antiviral%20response%20by%20promoting%20proteasomal%20degradation%20of%20TANK-binding%20kinase%201&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20120024&volume=209&pages=1703-1711&publication_year=2012&author=Zhang%2CM earn?
- What is the earnings of https://citation-needed.springer.com/v2/references/10.1038/ncomms13727?format=refman&flavour=references?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hui%20Song pull in monthly?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hui%20Song%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bingyu%20Liu's gross income?
- How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bingyu%20Liu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Wanwan%20Huai?
- What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Wanwan%20Huai%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Zhongxia%20Yu's revenue stream
- What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Zhongxia%20Yu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Wenwen%20Wang
- Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Wenwen%20Wang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jing%20Zhao?
- Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jing%20Zhao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lihui%20Han?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lihui%20Han%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Guosheng%20Jiang's earnings
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Guosheng%20Jiang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lining%20Zhang's revenue stream
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lining%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Chengjiang%20Gao earn?
- What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Chengjiang%20Gao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Wei%20Zhao bring in?
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Wei%20Zhao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- See how much https://static-content.springer.com/esm/art%3A10.1038%2Fncomms13727/MediaObjects/41467_2016_BFncomms13727_MOESM2015_ESM.pdf makes per month
- http://creativecommons.org/licenses/by/4.0/'s financial summary
- What's the profit of https://s100.copyright.com/AppDispatchServlet?title=The%20E3%20ubiquitin%20ligase%20TRIM31%20attenuates%20NLRP3%20inflammasome%20activation%20by%20promoting%20proteasomal%20degradation%20of%20NLRP3&author=Hui%20Song%20et%20al&contentID=10.1038%2Fncomms13727©right=The%20Author%28s%29&publication=2041-1723&publicationDate=2016-12-08&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY?
- https://crossmark.crossref.org/dialog/?doi=10.1038/ncomms13727's financial summary
- How much profit does https://citation-needed.springer.com/v2/references/10.1038/ncomms13727?format=refman&flavour=citation generate?
- Find out how much https://doi.org/10.1007/s10266-023-00813-0 earns monthly
- Monthly income for https://doi.org/10.1186/s12964-022-01022-y
- Income figures for https://doi.org/10.1186/s12964-022-00954-9
- How much does https://doi.org/10.1038/s41418-023-01115-2 pull in?
- Get to know what's the income of https://doi.org/10.1038/s41598-023-47139-z
- Discover the revenue of https://www.protocols.io/
- Revenue of https://www.natureindex.com/
- Find out how much http://www.naturechina.com earns monthly
- What is the monthly revenue of https://www.natureasia.com/ja-jp?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref