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         headline:Non-coding recurrent mutations in chronic lymphocytic leukaemia
         description:Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations determining the clinicobiological behaviour are not fully understood. Here we describe a comprehensive evaluation of the genomic landscape of 452 CLL cases and 54 patients with monoclonal B-lymphocytosis, a precursor disorder. We extend the number of CLL driver alterations, including changes in ZNF292, ZMYM3, ARID1A and PTPN11. We also identify novel recurrent mutations in non-coding regions, including the 3′ region of NOTCH1, which cause aberrant splicing events, increase NOTCH1 activity and result in a more aggressive disease. In addition, mutations in an enhancer located on chromosome 9p13 result in reduced expression of the B-cell-specific transcription factor PAX5. The accumulative number of driver alterations (0 to ≥4) discriminated between patients with differences in clinical behaviour. This study provides an integrated portrait of the CLL genomic landscape, identifies new recurrent driver mutations of the disease, and suggests clinical interventions that may improve the management of this neoplasia. Genomic approaches in more than 500 patients are used to extend the number of chronic lymphocytic leukaemia (CLL) driver alterations, and also identify novel recurrent mutations in non-coding regions, including an enhancer of PAX5 and the 3′ untranslated region of NOTCH1, which lead to aberrant splicing events, increased NOTCH1 protein stability and activity, and an adverse clinical outcome. This paper from the International Cancer Genomic Consortium reports the results of a number of genomic approaches used to characterize chronic lymphocytic leukaemia and its precursor in more than 500 patients. As well as extending the number of chronic lymphocytic leukaemia driver alterations found in the coding portion of the genome, the study identies novel recurrent mutations in non-coding regions, including the 3′ UTR of NOTCH1, which cause aberrant splicing events, an increase in NOTCH1 activity and more aggressive disease, as well as mutations in an enhancer which result in reduced expression of the B-cell-specific transcription factor PAX5.
         datePublished:2015-07-22T00:00:00Z
         dateModified:2015-10-22T00:00:00Z
         pageStart:519
         pageEnd:524
         sameAs:https://doi.org/10.1038/nature14666
         keywords:
            Cancer
            Science
            Humanities and Social Sciences
            multidisciplinary
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            issn:
               1476-4687
               0028-0836
            volumeNumber:526
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               name:Xose S. Puente
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                        name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
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                        name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
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                        type:PostalAddress
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               name:Nuria López-Bigas
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                     name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
                     address:
                        name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:David Torrents
               affiliation:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                     address:
                        name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
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               name:Ivo Gut
               affiliation:
                     name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona
                     address:
                        name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
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                     type:Organization
               type:Person
               name:Armando López-Guillermo
               affiliation:
                     name:Servicio de Hematología, Hospital Clínic, IDIBAPS
                     address:
                        name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Carlos López-Otín
               affiliation:
                     name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                     address:
                        name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Elías Campo
               affiliation:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                     address:
                        name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                        type:PostalAddress
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               email:[email protected]
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ScholarlyArticle:
      headline:Non-coding recurrent mutations in chronic lymphocytic leukaemia
      description:Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations determining the clinicobiological behaviour are not fully understood. Here we describe a comprehensive evaluation of the genomic landscape of 452 CLL cases and 54 patients with monoclonal B-lymphocytosis, a precursor disorder. We extend the number of CLL driver alterations, including changes in ZNF292, ZMYM3, ARID1A and PTPN11. We also identify novel recurrent mutations in non-coding regions, including the 3′ region of NOTCH1, which cause aberrant splicing events, increase NOTCH1 activity and result in a more aggressive disease. In addition, mutations in an enhancer located on chromosome 9p13 result in reduced expression of the B-cell-specific transcription factor PAX5. The accumulative number of driver alterations (0 to ≥4) discriminated between patients with differences in clinical behaviour. This study provides an integrated portrait of the CLL genomic landscape, identifies new recurrent driver mutations of the disease, and suggests clinical interventions that may improve the management of this neoplasia. Genomic approaches in more than 500 patients are used to extend the number of chronic lymphocytic leukaemia (CLL) driver alterations, and also identify novel recurrent mutations in non-coding regions, including an enhancer of PAX5 and the 3′ untranslated region of NOTCH1, which lead to aberrant splicing events, increased NOTCH1 protein stability and activity, and an adverse clinical outcome. This paper from the International Cancer Genomic Consortium reports the results of a number of genomic approaches used to characterize chronic lymphocytic leukaemia and its precursor in more than 500 patients. As well as extending the number of chronic lymphocytic leukaemia driver alterations found in the coding portion of the genome, the study identies novel recurrent mutations in non-coding regions, including the 3′ UTR of NOTCH1, which cause aberrant splicing events, an increase in NOTCH1 activity and more aggressive disease, as well as mutations in an enhancer which result in reduced expression of the B-cell-specific transcription factor PAX5.
      datePublished:2015-07-22T00:00:00Z
      dateModified:2015-10-22T00:00:00Z
      pageStart:519
      pageEnd:524
      sameAs:https://doi.org/10.1038/nature14666
      keywords:
         Cancer
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
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      isPartOf:
         name:Nature
         issn:
            1476-4687
            0028-0836
         volumeNumber:526
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
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         type:Organization
      author:
            name:Xose S. Puente
            affiliation:
                  name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                  address:
                     name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Silvia Beà
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rafael Valdés-Mas
            affiliation:
                  name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                  address:
                     name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Neus Villamor
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jesús Gutiérrez-Abril
            affiliation:
                  name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                  address:
                     name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:José I. Martín-Subero
            affiliation:
                  name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona
                  address:
                     name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marta Munar
            affiliation:
                  name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                  address:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Carlota Rubio-Pérez
            affiliation:
                  name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
                  address:
                     name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pedro Jares
            affiliation:
                  name:Unidad de Genómica, IDIBAPS
                  address:
                     name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marta Aymerich
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tycho Baumann
            affiliation:
                  name:Servicio de Hematología, Hospital Clínic, IDIBAPS
                  address:
                     name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Renée Beekman
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Laura Belver
            affiliation:
                  name:Institute for Cancer Genetics, Columbia University
                  address:
                     name:Institute for Cancer Genetics, Columbia University, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anna Carrio
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Giancarlo Castellano
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
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                  type:Organization
            type:Person
            name:Guillem Clot
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Enrique Colado
            affiliation:
                  name:Servicio de Hematología, Hospital Universitario Central de Asturias
                  address:
                     name:Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dolors Colomer
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dolors Costa
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Julio Delgado
            affiliation:
                  name:Servicio de Hematología, Hospital Clínic, IDIBAPS
                  address:
                     name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anna Enjuanes
            affiliation:
                  name:Unidad de Genómica, IDIBAPS
                  address:
                     name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Xavier Estivill
            affiliation:
                  name:Center for Genomic Regulation (CRG), Pompeu Fabra University (UPF), Hospital del Mar Research Institute (IMIM)
                  address:
                     name:Center for Genomic Regulation (CRG), Pompeu Fabra University (UPF), Hospital del Mar Research Institute (IMIM), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Adolfo A. Ferrando
            affiliation:
                  name:Institute for Cancer Genetics, Columbia University
                  address:
                     name:Institute for Cancer Genetics, Columbia University, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Josep L. Gelpí
            affiliation:
                  name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                  address:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Blanca González
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Santiago González
            affiliation:
                  name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                  address:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marcos González
            affiliation:
                  name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC
                  address:
                     name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marta Gut
            affiliation:
                  name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona
                  address:
                     name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jesús M. Hernández-Rivas
            affiliation:
                  name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC
                  address:
                     name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mónica López-Guerra
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David Martín-García
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alba Navarro
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pilar Nicolás
            affiliation:
                  name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco
                  address:
                     name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Modesto Orozco
            affiliation:
                  name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                  address:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ángel R. Payer
            affiliation:
                  name:Servicio de Hematología, Hospital Universitario Central de Asturias
                  address:
                     name:Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Magda Pinyol
            affiliation:
                  name:Unidad de Genómica, IDIBAPS
                  address:
                     name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David G. Pisano
            affiliation:
                  name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute
                  address:
                     name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Diana A. Puente
            affiliation:
                  name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                  address:
                     name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ana C. Queirós
            affiliation:
                  name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona
                  address:
                     name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Víctor Quesada
            affiliation:
                  name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
                  address:
                     name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Carlos M. Romeo-Casabona
            affiliation:
                  name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco
                  address:
                     name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Cristina Royo
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Romina Royo
            affiliation:
                  name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
                  address:
                     name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:María Rozman
            affiliation:
                  name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
                  address:
                     name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nuria Russiñol
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Itziar Salaverría
            affiliation:
                  name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
                  address:
                     name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kostas Stamatopoulos
            affiliation:
                  name:Institute of Applied Biosciences, Center for Research and Technology Hellas
                  address:
                     name:Institute of Applied Biosciences, Center for Research and Technology Hellas, Thermi, Greece
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hendrik G. Stunnenberg
            affiliation:
                  name:Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen
                  address:
                     name:Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David Tamborero
            affiliation:
                  name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
                  address:
                     name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:María J. Terol
            affiliation:
                  name:Servicio de Hematología, Hospital Clínico de Valencia
                  address:
                     name:Servicio de Hematología, Hospital Clínico de Valencia, Valencia, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alfonso Valencia
            affiliation:
                  name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute
                  address:
                     name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nuria López-Bigas
            affiliation:
                  name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
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      name:Josep L. Gelpí
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            name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
            address:
               name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Blanca González
      affiliation:
            name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
            address:
               name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Santiago González
      affiliation:
            name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
            address:
               name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Marcos González
      affiliation:
            name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC
            address:
               name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
               type:PostalAddress
            type:Organization
      name:Marta Gut
      affiliation:
            name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona
            address:
               name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Jesús M. Hernández-Rivas
      affiliation:
            name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC
            address:
               name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
               type:PostalAddress
            type:Organization
      name:Mónica López-Guerra
      affiliation:
            name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
            address:
               name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:David Martín-García
      affiliation:
            name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
            address:
               name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Alba Navarro
      affiliation:
            name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
            address:
               name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Pilar Nicolás
      affiliation:
            name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco
            address:
               name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
               type:PostalAddress
            type:Organization
      name:Modesto Orozco
      affiliation:
            name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
            address:
               name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Ángel R. Payer
      affiliation:
            name:Servicio de Hematología, Hospital Universitario Central de Asturias
            address:
               name:Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain
               type:PostalAddress
            type:Organization
      name:Magda Pinyol
      affiliation:
            name:Unidad de Genómica, IDIBAPS
            address:
               name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:David G. Pisano
      affiliation:
            name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute
            address:
               name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
               type:PostalAddress
            type:Organization
      name:Diana A. Puente
      affiliation:
            name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
            address:
               name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
               type:PostalAddress
            type:Organization
      name:Ana C. Queirós
      affiliation:
            name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona
            address:
               name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Víctor Quesada
      affiliation:
            name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
            address:
               name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
               type:PostalAddress
            type:Organization
      name:Carlos M. Romeo-Casabona
      affiliation:
            name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco
            address:
               name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
               type:PostalAddress
            type:Organization
      name:Cristina Royo
      affiliation:
            name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
            address:
               name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Romina Royo
      affiliation:
            name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
            address:
               name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:María Rozman
      affiliation:
            name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
            address:
               name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Nuria Russiñol
      affiliation:
            name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
            address:
               name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Itziar Salaverría
      affiliation:
            name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
            address:
               name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Kostas Stamatopoulos
      affiliation:
            name:Institute of Applied Biosciences, Center for Research and Technology Hellas
            address:
               name:Institute of Applied Biosciences, Center for Research and Technology Hellas, Thermi, Greece
               type:PostalAddress
            type:Organization
      name:Hendrik G. Stunnenberg
      affiliation:
            name:Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen
            address:
               name:Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
               type:PostalAddress
            type:Organization
      name:David Tamborero
      affiliation:
            name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
            address:
               name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:María J. Terol
      affiliation:
            name:Servicio de Hematología, Hospital Clínico de Valencia
            address:
               name:Servicio de Hematología, Hospital Clínico de Valencia, Valencia, Spain
               type:PostalAddress
            type:Organization
      name:Alfonso Valencia
      affiliation:
            name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute
            address:
               name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
               type:PostalAddress
            type:Organization
      name:Nuria López-Bigas
      affiliation:
            name:Research Unit on Biomedical Informatics, Universitat Pompeu Fabra
            address:
               name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:David Torrents
      affiliation:
            name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona
            address:
               name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Ivo Gut
      affiliation:
            name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona
            address:
               name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Armando López-Guillermo
      affiliation:
            name:Servicio de Hematología, Hospital Clínic, IDIBAPS
            address:
               name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Carlos López-Otín
      affiliation:
            name:Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo
            address:
               name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Elías Campo
      affiliation:
            name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona
            address:
               name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona, Barcelona, Spain
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
      name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Institute for Cancer Genetics, Columbia University, New York, USA
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
      name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
      name:Center for Genomic Regulation (CRG), Pompeu Fabra University (UPF), Hospital del Mar Research Institute (IMIM), Barcelona, Spain
      name:Institute for Cancer Genetics, Columbia University, New York, USA
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
      name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain
      name:Unidad de Genómica, IDIBAPS, Barcelona, Spain
      name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Departament d’Anatomía Patològica, Microbiología i Farmacología, Universitat de Barcelona, Barcelona, Spain
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Cátedra Inter-Universitaria de Derecho y Genoma Humano, Universidad de Deusto, Universidad del País Vasco, Bilbao, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
      name:Institute of Applied Biosciences, Center for Research and Technology Hellas, Thermi, Greece
      name:Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
      name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
      name:Servicio de Hematología, Hospital Clínico de Valencia, Valencia, Spain
      name:Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Spanish National Bioinformatics Institute, Madrid, Spain
      name:Department of Experimental and Health Sciences, Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain
      name:Programa Conjunto de Biología Computacional, Barcelona Supercomputing Center (BSC), Institut de Recerca Biomèdica (IRB), Spanish National Bioinformatics Institute, Universitat de Barcelona, Barcelona, Spain
      name:Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
      name:Servicio de Hematología, Hospital Clínic, IDIBAPS, Barcelona, Spain
      name:Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
      name:Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
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• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jos%C3%A9%20I.%20Mart%C3%ADn-Subero%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
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• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marta%20Munar%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carlota%20Rubio-P%C3%A9rez make?
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carlota%20Rubio-P%C3%A9rez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
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• Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pedro%20Jares%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Marta%20Aymerich rake in every month?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marta%20Aymerich%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
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• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tycho%20Baumann%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ren%C3%A9e%20Beekman generate?
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ren%C3%A9e%20Beekman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Laura%20Belver
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Laura%20Belver%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Anna%20Carrio generate monthly?
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• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Giancarlo%20Castellano%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Guillem%20Clot
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Guillem%20Clot%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
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• How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Enrique%20Colado%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
• How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dolors%20Colomer earning monthly?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dolors%20Colomer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
• Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dolors%20Costa
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dolors%20Costa%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Julio%20Delgado generate?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Julio%20Delgado%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Anna%20Enjuanes?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Anna%20Enjuanes%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xavier%20Estivill?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xavier%20Estivill%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Adolfo%20A.%20Ferrando pull in?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Adolfo%20A.%20Ferrando%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Josep%20L.%20Gelp%C3%AD making per month?
• Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Josep%20L.%20Gelp%C3%AD%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Blanca%20Gonz%C3%A1lez
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Blanca%20Gonz%C3%A1lez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Santiago%20Gonz%C3%A1lez make?
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Santiago%20Gonz%C3%A1lez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Marcos%20Gonz%C3%A1lez?
• What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marcos%20Gonz%C3%A1lez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Marta%20Gut generate?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marta%20Gut%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jes%C3%BAs%20M.%20Hern%C3%A1ndez-Rivas?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jes%C3%BAs%20M.%20Hern%C3%A1ndez-Rivas%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%C3%B3nica%20L%C3%B3pez-Guerra's total income per month
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%C3%B3nica%20L%C3%B3pez-Guerra%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=David%20Mart%C3%ADn-Garc%C3%ADa is on a monthly basis
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22David%20Mart%C3%ADn-Garc%C3%ADa%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alba%20Navarro
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alba%20Navarro%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pilar%20Nicol%C3%A1s
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pilar%20Nicol%C3%A1s%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Modesto%20Orozco?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Modesto%20Orozco%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
• What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=%C3%81ngel%20R.%20Payer?
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22%C3%81ngel%20R.%20Payer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Magda%20Pinyol generate monthly?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Magda%20Pinyol%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=David%20G.%20Pisano?
• How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22David%20G.%20Pisano%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Diana%20A.%20Puente?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Diana%20A.%20Puente%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
• What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ana%20C.%20Queir%C3%B3s?
• How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ana%20C.%20Queir%C3%B3s%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=V%C3%ADctor%20Quesada have?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22V%C3%ADctor%20Quesada%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
• What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carlos%20M.%20Romeo-Casabona?
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carlos%20M.%20Romeo-Casabona%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Cristina%20Royo?
• Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Cristina%20Royo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
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• What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mar%C3%ADa%20Rozman?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mar%C3%ADa%20Rozman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nuria%20Russi%C3%B1ol each month?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nuria%20Russi%C3%B1ol%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
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• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kostas%20Stamatopoulos is on a monthly basis
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kostas%20Stamatopoulos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
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• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=David%20Tamborero
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• How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mar%C3%ADa%20J.%20Terol%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
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• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nuria%20L%C3%B3pez-Bigas have monthly?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nuria%20L%C3%B3pez-Bigas%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=David%20Torrents's total income per month
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22David%20Torrents%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ivo%20Gut have monthly?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ivo%20Gut%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
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• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carlos%20L%C3%B3pez-Ot%C3%ADn pull in?
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carlos%20L%C3%B3pez-Ot%C3%ADn%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=El%C3%ADas%20Campo's financial summary
• Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22El%C3%ADas%20Campo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Revenue of https://static-content.springer.com/esm/art%3A10.1038%2Fnature14666/MediaObjects/41586_2015_BFnature14666_MOESM253_ESM.pdf
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