NATURE . COM {
}
Title:
Sequence analysis of mutations and translocations across breast cancer subtypes | Nature
Description:
This paper reports one of the largest breast cancer whole-exome and whole-genome sequencing efforts so far, identifying previously unknown recurrent mutations in CBFB, deletions of RUNX1 and recurrent MAGI1–AKT3 fusion; the fusion suggests that the use of ATP-competitive AKT inhibitors should be evaluated in clinical trials. This paper reports one of the largest whole-exome sequencing efforts in human breast cancers so far, complemented by whole-genome sequences of 22 breast cancer/normal pairs. The authors analysed diverse subtypes from patients in Mexico and Vietnam and identified recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1, as well as a recurrent MAGI3–AKT3 fusion enriched in triple-negative breast cancers (those lacking oestrogen and progesterone receptors and ERBB2 expression). The fusion leads to constitutive activation of AKT kinase, which can be counteracted by treatment with a small-molecule inhibitor. Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone1. This malignancy represents a heterogeneous group of tumours with characteristic molecular features, prognosis and responses to available therapy2,3,4. Recurrent somatic alterations in breast cancer have been described, including mutations and copy number alterations, notably ERBB2 amplifications, the first successful therapy target defined by a genomic aberration5. Previous DNA sequencing studies of breast cancer genomes have revealed additional candidate mutations and gene rearrangements6,7,8,9,10. Here we report the whole-exome sequences of DNA from 103 human breast cancers of diverse subtypes from patients in Mexico and Vietnam compared to matched-normal DNA, together with whole-genome sequences of 22 breast cancer/normal pairs. Beyond confirming recurrent somatic mutations in PIK3CA11, TP536, AKT112, GATA313 and MAP3K110, we discovered recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1. Furthermore, we have identified a recurrent MAGI3–AKT3 fusion enriched in triple-negative breast cancer lacking oestrogen and progesterone receptors and ERBB2 expression. The MAGI3–AKT3 fusion leads to constitutive activation of AKT kinase, which is abolished by treatment with an ATP-competitive AKT small-molecule inhibitor.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Science
- Education
- Health & Fitness
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌆 Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$531,700 per month
Our calculations suggest that Nature.com earns between $354,480 and $974,820 monthly online from display advertisements.
Keywords {🔍}
cancer, breast, mutations, article, nature, supplementary, sequencing, akt, gene, scholar, fusion, google, fig, cas, dna, samples, analysis, mutation, data, magiakt, ads, cancers, somatic, genomic, human, performed, usa, massachusetts, rearrangements, table, genes, subtypes, mexico, mutated, recurrent, wholeexome, cbfb, runx, expression, kinase, tumour, erbb, wholegenome, sample, domain, magi, institute, number, pikca, methods,
Topics {✒️}
nature portfolio privacy policy core-binding-factor beta subunit hormone-receptor-negative breast cancers29 advertising gerardo jimenez-sanchez oestrogen-receptor-positive breast cancers10 chimeric gene cbfb/pebp2b-mhy11 library construction uk/genetics/cgp/cosmic/ low-serum media reprints atp-competitive akt inhibitors triple-negative breast cancers v-erbb-related gene small-cell lung cancer dana-farber/harvard spore dana-farber cancer institute oestrogen-receptor-positive disease notch family-gene fusions25 antonio maffuz-aziz disrupts zinc-finger domains alfredo hidalgo-miranda target protein-coding regions predicted 5′-magi3–akt3-3′ fusion org/display/cgatools/mutect org/display/cgatools/indelocator org/display/cgatools/home social media nature biotechnol nature med shin nature magi3–akt3 fusion protein oestrogen-receptor-positive subtypes van de sluis mass-spectrometry-based genotyping commercial-share alike licence inferred segmental copy-ratios accession number phs000369 tumour/normal dna pairs higher copy-ratio allele magi3–akt3 overexpressing cells magi3–akt3 fusion gene oestrogen-receptor-positive samples allele-specific copy number small-molecule inhibitor protein-altering point mutations org/display/cgatools/mutsig received fellowship support 5′-magi3–akt3-3′ fusion event
Schema {🗺️}
WebPage:
mainEntity:
headline:Sequence analysis of mutations and translocations across breast cancer subtypes
description:This paper reports one of the largest breast cancer whole-exome and whole-genome sequencing efforts so far, identifying previously unknown recurrent mutations in CBFB, deletions of RUNX1 and recurrent MAGI1âAKT3 fusion; the fusion suggests that the use of ATP-competitive AKT inhibitors should be evaluated in clinical trials. This paper reports one of the largest whole-exome sequencing efforts in human breast cancers so far, complemented by whole-genome sequences of 22 breast cancer/normal pairs. The authors analysed diverse subtypes from patients in Mexico and Vietnam and identified recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1, as well as a recurrent MAGI3âAKT3 fusion enriched in triple-negative breast cancers (those lacking oestrogen and progesterone receptors and ERBB2 expression). The fusion leads to constitutive activation of AKT kinase, which can be counteracted by treatment with a small-molecule inhibitor. Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone1. This malignancy represents a heterogeneous group of tumours with characteristic molecular features, prognosis and responses to available therapy2,3,4. Recurrent somatic alterations in breast cancer have been described, including mutations and copy number alterations, notably ERBB2 amplifications, the first successful therapy target defined by a genomic aberration5. Previous DNA sequencing studies of breast cancer genomes have revealed additional candidate mutations and gene rearrangements6,7,8,9,10. Here we report the whole-exome sequences of DNA from 103 human breast cancers of diverse subtypes from patients in Mexico and Vietnam compared to matched-normal DNA, together with whole-genome sequences of 22 breast cancer/normal pairs. Beyond confirming recurrent somatic mutations in PIK3CA11, TP536, AKT112, GATA313 and MAP3K110, we discovered recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1. Furthermore, we have identified a recurrent MAGI3âAKT3 fusion enriched in triple-negative breast cancer lacking oestrogen and progesterone receptors and ERBB2 expression. The MAGI3âAKT3 fusion leads to constitutive activation of AKT kinase, which is abolished by treatment with an ATP-competitive AKT small-molecule inhibitor.
datePublished:2012-06-20T00:00:00Z
dateModified:2012-06-20T00:00:00Z
pageStart:405
pageEnd:409
license:http://creativecommons.org/licenses/by-nc-sa/3.0/
sameAs:https://doi.org/10.1038/nature11154
keywords:
Breast cancer
Cancer genetics
DNA sequencing
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig3_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:486
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Shantanu Banerji
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
type:Person
name:Kristian Cibulskis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Claudia Rangel-Escareno
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Kristin K. Brown
affiliation:
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
type:Person
name:Scott L. Carter
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Abbie M. Frederick
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Michael S. Lawrence
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Andrey Y. Sivachenko
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Carrie Sougnez
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Lihua Zou
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Maria L. Cortes
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Juan C. Fernandez-Lopez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Shouyong Peng
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Kristin G. Ardlie
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Daniel Auclair
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Veronica Bautista-Piña
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Fujiko Duke
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Joshua Francis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Joonil Jung
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Antonio Maffuz-Aziz
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Robert C. Onofrio
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Melissa Parkin
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Nam H. Pho
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Valeria Quintanar-Jurado
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Alex H. Ramos
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Rosa Rebollar-Vega
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Sergio Rodriguez-Cuevas
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Sandra L. Romero-Cordoba
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Steven E. Schumacher
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Nicolas Stransky
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Kristin M. Thompson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Laura Uribe-Figueroa
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Jose Baselga
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts General Hospital
address:
name:Division of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Rameen Beroukhim
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Kornelia Polyak
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Womenâs Hospital
address:
name:Department of Medicine, Brigham and Womenâs Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Dennis C. Sgroi
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Depertment of Pathology, Massachusetts General Hospital
address:
name:Depertment of Pathology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Andrea L. Richardson
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Women's Hospital
address:
name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Gerardo Jimenez-Sanchez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
type:Person
name:Eric S. Lander
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts Institute of Technology
address:
name:Massachusetts Institute of Technology, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Stacey B. Gabriel
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Levi A. Garraway
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Todd R. Golub
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Howard Hughes Medical Institute
address:
name:Howard Hughes Medical Institute, Chevy Chase, USA
type:PostalAddress
type:Organization
type:Person
name:Jorge Melendez-Zajgla
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Alex Toker
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Gad Getz
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Alfredo Hidalgo-Miranda
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Matthew Meyerson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Sequence analysis of mutations and translocations across breast cancer subtypes
description:This paper reports one of the largest breast cancer whole-exome and whole-genome sequencing efforts so far, identifying previously unknown recurrent mutations in CBFB, deletions of RUNX1 and recurrent MAGI1âAKT3 fusion; the fusion suggests that the use of ATP-competitive AKT inhibitors should be evaluated in clinical trials. This paper reports one of the largest whole-exome sequencing efforts in human breast cancers so far, complemented by whole-genome sequences of 22 breast cancer/normal pairs. The authors analysed diverse subtypes from patients in Mexico and Vietnam and identified recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1, as well as a recurrent MAGI3âAKT3 fusion enriched in triple-negative breast cancers (those lacking oestrogen and progesterone receptors and ERBB2 expression). The fusion leads to constitutive activation of AKT kinase, which can be counteracted by treatment with a small-molecule inhibitor. Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone1. This malignancy represents a heterogeneous group of tumours with characteristic molecular features, prognosis and responses to available therapy2,3,4. Recurrent somatic alterations in breast cancer have been described, including mutations and copy number alterations, notably ERBB2 amplifications, the first successful therapy target defined by a genomic aberration5. Previous DNA sequencing studies of breast cancer genomes have revealed additional candidate mutations and gene rearrangements6,7,8,9,10. Here we report the whole-exome sequences of DNA from 103 human breast cancers of diverse subtypes from patients in Mexico and Vietnam compared to matched-normal DNA, together with whole-genome sequences of 22 breast cancer/normal pairs. Beyond confirming recurrent somatic mutations in PIK3CA11, TP536, AKT112, GATA313 and MAP3K110, we discovered recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1. Furthermore, we have identified a recurrent MAGI3âAKT3 fusion enriched in triple-negative breast cancer lacking oestrogen and progesterone receptors and ERBB2 expression. The MAGI3âAKT3 fusion leads to constitutive activation of AKT kinase, which is abolished by treatment with an ATP-competitive AKT small-molecule inhibitor.
datePublished:2012-06-20T00:00:00Z
dateModified:2012-06-20T00:00:00Z
pageStart:405
pageEnd:409
license:http://creativecommons.org/licenses/by-nc-sa/3.0/
sameAs:https://doi.org/10.1038/nature11154
keywords:
Breast cancer
Cancer genetics
DNA sequencing
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_Article_BFnature11154_Fig3_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:486
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Shantanu Banerji
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
type:Person
name:Kristian Cibulskis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Claudia Rangel-Escareno
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Kristin K. Brown
affiliation:
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
type:Person
name:Scott L. Carter
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Abbie M. Frederick
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Michael S. Lawrence
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Andrey Y. Sivachenko
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Carrie Sougnez
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Lihua Zou
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Maria L. Cortes
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Juan C. Fernandez-Lopez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Shouyong Peng
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Kristin G. Ardlie
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Daniel Auclair
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Veronica Bautista-Piña
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Fujiko Duke
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Joshua Francis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Joonil Jung
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Antonio Maffuz-Aziz
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Robert C. Onofrio
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Melissa Parkin
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Nam H. Pho
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Valeria Quintanar-Jurado
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Alex H. Ramos
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Rosa Rebollar-Vega
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Sergio Rodriguez-Cuevas
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Sandra L. Romero-Cordoba
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Steven E. Schumacher
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Nicolas Stransky
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Kristin M. Thompson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Laura Uribe-Figueroa
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Jose Baselga
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts General Hospital
address:
name:Division of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Rameen Beroukhim
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Kornelia Polyak
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Womenâs Hospital
address:
name:Department of Medicine, Brigham and Womenâs Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Dennis C. Sgroi
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Depertment of Pathology, Massachusetts General Hospital
address:
name:Depertment of Pathology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Andrea L. Richardson
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Women's Hospital
address:
name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Gerardo Jimenez-Sanchez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
type:Person
name:Eric S. Lander
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts Institute of Technology
address:
name:Massachusetts Institute of Technology, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Stacey B. Gabriel
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Levi A. Garraway
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Todd R. Golub
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Howard Hughes Medical Institute
address:
name:Howard Hughes Medical Institute, Chevy Chase, USA
type:PostalAddress
type:Organization
type:Person
name:Jorge Melendez-Zajgla
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
type:Person
name:Alex Toker
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Gad Getz
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Alfredo Hidalgo-Miranda
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Matthew Meyerson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:486
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Massachusetts General Hospital
address:
name:Division of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Brigham and Womenâs Hospital
address:
name:Department of Medicine, Brigham and Womenâs Hospital, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Depertment of Pathology, Massachusetts General Hospital
address:
name:Depertment of Pathology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Brigham and Women's Hospital
address:
name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Massachusetts Institute of Technology
address:
name:Massachusetts Institute of Technology, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Howard Hughes Medical Institute
address:
name:Howard Hughes Medical Institute, Chevy Chase, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Shantanu Banerji
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
name:Kristian Cibulskis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Claudia Rangel-Escareno
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Kristin K. Brown
affiliation:
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
name:Scott L. Carter
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Abbie M. Frederick
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Michael S. Lawrence
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Andrey Y. Sivachenko
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Carrie Sougnez
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Lihua Zou
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Maria L. Cortes
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Juan C. Fernandez-Lopez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Shouyong Peng
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Kristin G. Ardlie
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Daniel Auclair
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Veronica Bautista-Piña
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Fujiko Duke
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Joshua Francis
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Joonil Jung
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Antonio Maffuz-Aziz
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Robert C. Onofrio
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Melissa Parkin
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Nam H. Pho
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Valeria Quintanar-Jurado
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Alex H. Ramos
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Rosa Rebollar-Vega
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Sergio Rodriguez-Cuevas
affiliation:
name:Instituto de Enfermedades de la Mama FUCAM
address:
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Sandra L. Romero-Cordoba
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Steven E. Schumacher
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Nicolas Stransky
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Kristin M. Thompson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Laura Uribe-Figueroa
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Jose Baselga
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts General Hospital
address:
name:Division of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
name:Rameen Beroukhim
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Kornelia Polyak
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Womenâs Hospital
address:
name:Department of Medicine, Brigham and Womenâs Hospital, Boston, USA
type:PostalAddress
type:Organization
name:Dennis C. Sgroi
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Depertment of Pathology, Massachusetts General Hospital
address:
name:Depertment of Pathology, Massachusetts General Hospital, Boston, USA
type:PostalAddress
type:Organization
name:Andrea L. Richardson
affiliation:
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Brigham and Women's Hospital
address:
name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
type:PostalAddress
type:Organization
name:Gerardo Jimenez-Sanchez
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).
address:
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
type:PostalAddress
type:Organization
name:Eric S. Lander
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Massachusetts Institute of Technology
address:
name:Massachusetts Institute of Technology, Cambridge, USA
type:PostalAddress
type:Organization
name:Stacey B. Gabriel
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Levi A. Garraway
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Todd R. Golub
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Howard Hughes Medical Institute
address:
name:Howard Hughes Medical Institute, Chevy Chase, USA
type:PostalAddress
type:Organization
name:Jorge Melendez-Zajgla
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
name:Alex Toker
affiliation:
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215
address:
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
type:PostalAddress
type:Organization
email:[email protected]
name:Gad Getz
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
name:Alfredo Hidalgo-Miranda
affiliation:
name:Instituto Nacional de Medicina Genómica
address:
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
type:PostalAddress
type:Organization
email:[email protected]
name:Matthew Meyerson
affiliation:
name:The Broad Institute of MIT and Harvard
address:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dana-Farber Cancer Institute
address:
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Instituto de Enfermedades de la Mama FUCAM, Mexico City, Mexico
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Harvard Medical School, Boston, USA
name:Division of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:Department of Medicine, Brigham and Womenâs Hospital, Boston, USA
name:Harvard Medical School, Boston, USA
name:Depertment of Pathology, Massachusetts General Hospital, Boston, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:Department of Pathology, Brigham and Women's Hospital, Boston, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Present addresses: Department of Medical Oncology, CancerCare Manitoba, Winnipeg, Manitoba R3E 0V9, Canada (S.B.); Global Biotech Consulting Group, Mexico City 01900, Mexico (G.J.-S.).,
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Harvard Medical School, Boston, USA
name:Massachusetts Institute of Technology, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Harvard Medical School, Boston, USA
name:Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Howard Hughes Medical Institute, Chevy Chase, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:Harvard Medical School, Boston, USA
name:Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215,
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Instituto Nacional de Medicina Genómica, Mexico City, Mexico
name:The Broad Institute of MIT and Harvard, Cambridge, USA
name:Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
name:Harvard Medical School, Boston, USA
name:Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA
External Links {🔗}(195)
- Profit of https://confluence.broadinstitute.org/display/CGATools/MuTect
- What is the monthly revenue of https://confluence.broadinstitute.org/display/CGATools/Indelocator?
- How much income is https://confluence.broadinstitute.org/display/CGATools/MutSig earning monthly?
- What's the profit of http://www.sanger.ac.uk/genetics/CGP/cosmic/?
- Get to know what's the income of https://confluence.broadinstitute.org/display/CGATools/Home
- What's the financial intake of http://www.pdb.org/pdb/search/structidSearch.do?structureId=phs000369.v1.p1?
- How much does http://www.ncbi.nlm.nih.gov/gap gross monthly?
- How much revenue does https://doi.org/10.3322%2Fcaac.20107 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Global%20cancer%20statistics&journal=CA%20Cancer%20J.%20Clin.&doi=10.3322%2Fcaac.20107&volume=61&pages=69-90&publication_year=2011&author=Jemal%2CA generate monthly?
- https://doi.org/10.1073%2Fpnas.191367098's total income per month
- What's the revenue for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2001PNAS...9810869S?
- Get to know http://scholar.google.com/scholar_lookup?&title=Gene%20expression%20patterns%20of%20breast%20carcinomas%20distinguish%20tumor%20subclasses%20with%20clinical%20implications&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.191367098&volume=98&pages=10869-10874&publication_year=2001&author=S%C3%B8rlie%2CT's earnings
- What's https://doi.org/10.1016%2Fj.ccr.2006.10.009's gross income?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Genomic%20and%20transcriptional%20aberrations%20linked%20to%20breast%20cancer%20pathophysiologies&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2006.10.009&volume=10&pages=529-541&publication_year=2006&author=Chin%2CK
- How much does https://doi.org/10.1073%2Fpnas.0912708107 net monthly?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2010PNAS..107.6994G rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=A%20pathway-based%20classification%20of%20human%20breast%20cancer&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0912708107&volume=107&pages=6994-6999&publication_year=2010&author=Gatza%2CML make?
- What's the monthly money flow for https://doi.org/10.1126%2Fscience.2992089?
- What is the monthly revenue of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1985Sci...229..974R?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Amplification%20of%20a%20novel%20v-erbB-related%20gene%20in%20a%20human%20mammary%20carcinoma&journal=Science&doi=10.1126%2Fscience.2992089&volume=229&pages=974-976&publication_year=1985&author=King%2CCR&author=Kraus%2CMH&author=Aaronson%2CSA have monthly?
- How much revenue does https://doi.org/10.1126%2Fscience.1133427 generate?
- What's the income of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2006Sci...314..268S?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=The%20consensus%20coding%20sequences%20of%20human%20breast%20and%20colorectal%20cancers&journal=Science&doi=10.1126%2Fscience.1133427&volume=314&pages=268-274&publication_year=2006&author=Sj%C3%B6blom%2CT each month?
- What is the monthly revenue of https://doi.org/10.1126%2Fscience.1145720?
- http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007Sci...318.1108W's financial summary
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=The%20genomic%20landscapes%20of%20human%20breast%20and%20colorectal%20cancers&journal=Science&doi=10.1126%2Fscience.1145720&volume=318&pages=1108-1113&publication_year=2007&author=Wood%2CLD?
- How much cash flow does https://doi.org/10.1038%2Fnature08489 have monthly?
- http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2009Natur.461..809S's total income per month
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Mutational%20evolution%20in%20a%20lobular%20breast%20tumour%20profiled%20at%20single%20nucleotide%20resolution&journal=Nature&doi=10.1038%2Fnature08489&volume=461&pages=809-813&publication_year=2009&author=Shah%2CSP?
- What's the financial outcome of https://doi.org/10.1038%2Fnature08989?
- Earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2010Natur.464..999D
- http://scholar.google.com/scholar_lookup?&title=Genome%20remodelling%20in%20a%20basal-like%20breast%20cancer%20metastasis%20and%20xenograft&journal=Nature&doi=10.1038%2Fnature08989&volume=464&pages=999-1005&publication_year=2010&author=Ding%2CL's total income per month
- What's the monthly money flow for https://doi.org/10.1038%2Fnature09208?
- What's the revenue for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2010Natur.466..869K?
- Get to know http://scholar.google.com/scholar_lookup?&title=Diverse%20somatic%20mutation%20patterns%20and%20pathway%20alterations%20in%20human%20cancers&journal=Nature&doi=10.1038%2Fnature09208&volume=466&pages=869-873&publication_year=2010&author=Kan%2CZ's earnings
- How profitable is https://doi.org/10.1126%2Fscience.1096502?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=High%20frequency%20of%20mutations%20of%20the%20PIK3CA%20gene%20in%20human%20cancers&journal=Science&doi=10.1126%2Fscience.1096502&volume=304&publication_year=2004&author=Samuels%2CY?
- How much does https://doi.org/10.1038%2Fnature05933 earn?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007Natur.448..439C generate monthly?
- Profit of http://scholar.google.com/scholar_lookup?&title=A%20transforming%20mutation%20in%20the%20pleckstrin%20homology%20domain%20of%20AKT1%20in%20cancer&journal=Nature&doi=10.1038%2Fnature05933&volume=448&pages=439-444&publication_year=2007&author=Carpten%2CJD
- Revenue of https://doi.org/10.1038%2Fsj.onc.1207966
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Mutation%20of%20GATA3%20in%20human%20breast%20tumors&journal=Oncogene&doi=10.1038%2Fsj.onc.1207966&volume=23&pages=7669-7678&publication_year=2004&author=Usary%2CJ?
- How much does https://doi.org/10.1073%2Fpnas.0932692100 pull in monthly?
- What's the profit of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003PNAS..100.8418S?
- How much does http://scholar.google.com/scholar_lookup?&title=Repeated%20observation%20of%20breast%20tumor%20subtypes%20in%20independent%20gene%20expression%20data%20sets&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0932692100&volume=100&pages=8418-8423&publication_year=2003&author=Sorlie%2CT pull in?
- https://doi.org/10.1038%2Fnature08645's financial summary
- How much income is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2009Natur.462.1005S earning monthly?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Complex%20landscapes%20of%20somatic%20rearrangement%20in%20human%20breast%20cancer%20genomes&journal=Nature&doi=10.1038%2Fnature08645&volume=462&pages=1005-1010&publication_year=2009&author=Stephens%2CPJ?
- Learn about the earnings of https://doi.org/10.1038%2Fnature09744
- How much profit is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2011Natur.470..214B making per month?
- How much profit is http://scholar.google.com/scholar_lookup?&title=The%20genomic%20complexity%20of%20primary%20human%20prostate%20cancer&journal=Nature&doi=10.1038%2Fnature09744&volume=470&pages=214-220&publication_year=2011&author=Berger%2CMF making per month?
- How much income is https://doi.org/10.1038%2Fnature09837 earning monthly?
- Financial intake of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2011Natur.471..467C
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Initial%20genome%20sequencing%20and%20analysis%20of%20multiple%20myeloma&journal=Nature&doi=10.1038%2Fnature09837&volume=471&pages=467-472&publication_year=2011&author=Chapman%2CMA?
- https://doi.org/10.1038%2Fnature08658's revenue stream
- How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2010Natur.463..191P generate?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=A%20comprehensive%20catalogue%20of%20somatic%20mutations%20from%20a%20human%20cancer%20genome&journal=Nature&doi=10.1038%2Fnature08658&volume=463&pages=191-196&publication_year=2010&author=Pleasance%2CED?
- Learn about the earnings of https://doi.org/10.1038%2Fnature08629
- How much income does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2010Natur.463..184P have?
- How profitable is http://scholar.google.com/scholar_lookup?&title=A%20small-cell%20lung%20cancer%20genome%20with%20complex%20signatures%20of%20tobacco%20exposure&journal=Nature&doi=10.1038%2Fnature08629&volume=463&pages=184-190&publication_year=2010&author=Pleasance%2CED?
- https://doi.org/10.4161%2Fcbt.3.8.994's total income per month
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=The%20PIK3CA%20gene%20is%20mutated%20with%20high%20frequency%20in%20human%20breast%20cancers&journal=Cancer%20Biol.%20Ther.&doi=10.4161%2Fcbt.3.8.994&volume=3&pages=772-775&publication_year=2004&author=Bachman%2CKE?
- How much does https://doi.org/10.1038%2Fsj.onc.1207130 make?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=The%20Runx%20genes%3A%20lineage-specific%20oncogenes%20and%20tumor%20suppressors&journal=Oncogene&doi=10.1038%2Fsj.onc.1207130&volume=23&pages=4308-4314&publication_year=2004&author=Cameron%2CER&author=Neil%2CJC
- What's the financial intake of https://doi.org/10.1038%2Fsj.onc.1207748?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Mechanism%20of%20leukemogenesis%20by%20the%20inv%2816%29%20chimeric%20gene%20CBFB%2FPEBP2B-MHY11&journal=Oncogene&doi=10.1038%2Fsj.onc.1207748&volume=23&pages=4297-4307&publication_year=2004&author=Shigesada%2CK&author=van%20de%20Sluis%2CB&author=Liu%2CPP
- How much profit is https://doi.org/10.1038%2F431525b making per month?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2004Natur.431..525S bring in each month?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Lung%20cancer%3A%20intragenic%20ERBB2%20kinase%20mutations%20in%20tumours&journal=Nature&doi=10.1038%2F431525b&volume=431&pages=525-526&publication_year=2004&author=Stephens%2CP make?
- How much does https://doi.org/10.1038%2Fnm.2580 generate monthly?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Functionally%20recurrent%20rearrangements%20of%20the%20MAST%20kinase%20and%20Notch%20gene%20families%20in%20breast%20cancer&journal=Nature%20Med.&doi=10.1038%2Fnm.2580&volume=17&pages=1646-1651&publication_year=2011&author=Robinson%2CDR have monthly?
- Check the income stats for https://doi.org/10.1038%2Fnature05945
- See how much http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007Natur.448..561S makes per month
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Identification%20of%20the%20transforming%20EML4%E2%80%93ALK%20fusion%20gene%20in%20non-small-cell%20lung%20cancer&journal=Nature&doi=10.1038%2Fnature05945&volume=448&pages=561-566&publication_year=2007&author=Soda%2CM?
- How much does https://doi.org/10.1126%2Fscience.1117679 generate monthly?
- How much money does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2005Sci...310..644T generate?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Recurrent%20fusion%20of%20TMPRSS2%20and%20ETS%20transcription%20factor%20genes%20in%20prostate%20cancer&journal=Science&doi=10.1126%2Fscience.1117679&volume=310&pages=644-648&publication_year=2005&author=Tomlins%2CSA
- What's the revenue for https://doi.org/10.1074%2Fjbc.M909741199?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Interaction%20of%20the%20tumor%20Suppressor%20PTEN%2FMMAC%20with%20a%20PDZ%20domain%20of%20MAGI3%2C%20a%20novel%20membrane-associated%20guanylate%20kinase&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M909741199&volume=275&pages=21477-21485&publication_year=2000&author=Wu%2CY?
- https://doi.org/10.1074%2Fjbc.274.31.21528's total income per month
- http://scholar.google.com/scholar_lookup?&title=Up-regulation%20of%20Akt3%20in%20estrogen%20receptor-deficient%20breast%20cancers%20and%20androgen-independent%20prostate%20cancer%20lines&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.274.31.21528&volume=274&pages=21528-21532&publication_year=1999&author=Nakatani%2CK's total income per month
- How much income is https://citation-needed.springer.com/v2/references/10.1038/nature11154?format=refman&flavour=references earning monthly?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Shantanu%20Banerji's revenue stream
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Shantanu%20Banerji%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kristian%20Cibulskis?
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kristian%20Cibulskis%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Claudia%20Rangel-Escareno?
- What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Claudia%20Rangel-Escareno%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kristin%20K.%20Brown?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kristin%20K.%20Brown%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Scott%20L.%20Carter each month?
- Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Scott%20L.%20Carter%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Abbie%20M.%20Frederick
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Abbie%20M.%20Frederick%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20S.%20Lawrence?
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20S.%20Lawrence%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Andrey%20Y.%20Sivachenko making per month?
- What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Andrey%20Y.%20Sivachenko%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carrie%20Sougnez's gross income?
- How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carrie%20Sougnez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lihua%20Zou
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lihua%20Zou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maria%20L.%20Cortes income
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maria%20L.%20Cortes%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Juan%20C.%20Fernandez-Lopez pull in monthly?
- Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Juan%20C.%20Fernandez-Lopez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Shouyong%20Peng generate?
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Shouyong%20Peng%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kristin%20G.%20Ardlie?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kristin%20G.%20Ardlie%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Daniel%20Auclair
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Daniel%20Auclair%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
- Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Veronica%20Bautista-Pi%C3%B1a
- What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Veronica%20Bautista-Pi%C3%B1a%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Fujiko%20Duke have?
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Fujiko%20Duke%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joshua%20Francis generate?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joshua%20Francis%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
- What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joonil%20Jung?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joonil%20Jung%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
- What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Antonio%20Maffuz-Aziz?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Antonio%20Maffuz-Aziz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Robert%20C.%20Onofrio
- Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Robert%20C.%20Onofrio%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Melissa%20Parkin?
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Melissa%20Parkin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nam%20H.%20Pho
- What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nam%20H.%20Pho%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Valeria%20Quintanar-Jurado make?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Valeria%20Quintanar-Jurado%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alex%20H.%20Ramos
- Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alex%20H.%20Ramos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rosa%20Rebollar-Vega generate?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rosa%20Rebollar-Vega%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sergio%20Rodriguez-Cuevas?
- What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sergio%20Rodriguez-Cuevas%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sandra%20L.%20Romero-Cordoba
- What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sandra%20L.%20Romero-Cordoba%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Steven%20E.%20Schumacher generate?
- How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Steven%20E.%20Schumacher%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicolas%20Stransky
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicolas%20Stransky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kristin%20M.%20Thompson's financial summary
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kristin%20M.%20Thompson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Laura%20Uribe-Figueroa earning monthly?
- What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Laura%20Uribe-Figueroa%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jose%20Baselga?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jose%20Baselga%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rameen%20Beroukhim earning monthly?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rameen%20Beroukhim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kornelia%20Polyak?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kornelia%20Polyak%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dennis%20C.%20Sgroi?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dennis%20C.%20Sgroi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
- How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Andrea%20L.%20Richardson?
- Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Andrea%20L.%20Richardson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gerardo%20Jimenez-Sanchez
- Monthly income for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gerardo%20Jimenez-Sanchez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eric%20S.%20Lander gross monthly?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eric%20S.%20Lander%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Stacey%20B.%20Gabriel's total income per month
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Stacey%20B.%20Gabriel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Levi%20A.%20Garraway?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Levi%20A.%20Garraway%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
- Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Todd%20R.%20Golub
- How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Todd%20R.%20Golub%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jorge%20Melendez-Zajgla make?
- How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jorge%20Melendez-Zajgla%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
- What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alex%20Toker?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alex%20Toker%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gad%20Getz earning monthly?
- What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gad%20Getz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alfredo%20Hidalgo-Miranda
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alfredo%20Hidalgo-Miranda%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Matthew%20Meyerson make?
- See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Matthew%20Meyerson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
- See how much https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM316_ESM.pdf makes per month
- Profit of https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM317_ESM.xls
- What are the total earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM318_ESM.xls?
- What's https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM319_ESM.xls's gross income?
- What's the income of https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM313_ESM.ppt?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM314_ESM.ppt make?
- How much revenue does https://static-content.springer.com/esm/art%3A10.1038%2Fnature11154/MediaObjects/41586_2012_BFnature11154_MOESM315_ESM.ppt bring in?
- Profit of http://creativecommons.org/licenses/by-nc-sa/3.0/
- How much does https://s100.copyright.com/AppDispatchServlet?title=Sequence%20analysis%20of%20mutations%20and%20translocations%20across%20breast%20cancer%20subtypes&author=Shantanu%20Banerji%20et%20al&contentID=10.1038%2Fnature11154©right=The%20Author%28s%29&publication=0028-0836&publicationDate=2012-06-20&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY-NC-SA rake in every month?
- https://citation-needed.springer.com/v2/references/10.1038/nature11154?format=refman&flavour=citation's total income per month
- Find out how much https://doi.org/10.1186/s40246-023-00511-6 earns monthly
- https://doi.org/10.1186/s12864-023-09515-x's total income per month
- Check the income stats for https://doi.org/10.1007/s10577-023-09732-w
- How much does https://doi.org/10.1007/s40203-023-00152-6 make?
- Learn about the earnings of https://doi.org/10.1186/s10020-022-00479-4
- How much does https://www.protocols.io/ net monthly?
- How much does https://www.natureindex.com/ pull in?
- How much does http://www.naturechina.com earn?
- https://www.natureasia.com/ja-jp's financial summary
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref