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crispr/cas9-based genome-wide screening nature portfolio permissions reprints short-interfering-rna-mediated knockdown privacy policy germ-line-competent embryonic stem advertising nature cell biol social media re1-silencing transcription factor nature rev nature med stanton nature fisher nature early embryonic development nature genet /neuron-restrictive silencer factor nature 444 nature 453 nature neural stem/progenitor cells jørgensenzhou-feng chenamanda brain tumor center neuronal repressor rest/nrsf personal data springerlink instant access data protection permissions mouse embryonic stem rest/nrsf target genes author contributions author correspondence newly discovered element embryonic stem cells exogenously added rest neuronal repressor rest neural stem cells privacy α-fetoprotein transcription interconnected regulatory network promoter analysis based stem cell differentiation mouse es cells differentiating mouse es gene regulatory network blocking neuronal differentiation mouse eb cells jan parker-thornburg mirna target sites protein interaction network

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• Can controversies be put to REST?
• Is REST a regulator of pluripotency?
• Is REST required for ESC pluripotency?

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      headline:REST maintains self-renewal and pluripotency of embryonic stem cells
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