
NATURE . COM {
}
Title:
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor | Nature
Description:
Haematopoietic stem cells βhomeβ to the bone marrow during embryogenesis and after bone marrow transplants. With the exception of integrins, the molecules that mediate this process are largely unknown. Now Adams et al. have identified another factor essential for homing, a membrane-spanning molecule called calcium-sensing receptor (CaR). Cells lacking CaR divide normally, but the newly formed cells are unable to migrate and home to the bone marrow. This newly recognized participant in the localization and engraftment of stem cells provides a potential target for affecting that process. During mammalian ontogeny, haematopoietic stem cells (HSCs) translocate from the fetal liver to the bone marrow, where haematopoiesis occurs throughout adulthood1. Unique features of bone that contribute to a microenvironmental niche for stem cells might include the known high concentration of calcium ions at the HSC-enriched endosteal surface. Cells respond to extracellular ionic calcium concentrations through the seven-transmembrane-spanning calcium-sensing receptor (CaR), which we identified as being expressed on HSCs. Here we show that, through the CaR, the simple ionic mineral content of the niche may dictate the preferential localization of adult mammalian haematopoiesis in bone. Antenatal mice deficient in CaR had primitive haematopoietic cells in the circulation and spleen, whereas few were found in bone marrow. CaR-/- HSCs from fetal liver were normal in number, in proliferative and differentiative function, and in migration and homing to the bone marrow. Yet they were highly defective in localizing anatomically to the endosteal niche, behaviour that correlated with defective adhesion to the extracellular matrix protein, collagen I. CaR has a function in retaining HSCs in close physical proximity to the endosteal surface and the regulatory niche components associated with it.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Science
- Education
- Insurance
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.
Keywords {π}
article, cells, google, scholar, nature, stem, cas, bone, cell, marrow, car, niche, access, hematopoietic, content, haematopoietic, calciumsensing, receptor, scadden, blood, pubmed, cookies, endosteal, mice, expression, usa, research, privacy, information, adams, extracellular, ads, massachusetts, analysis, data, journal, engraftment, chabner, alley, zbigniew, szczepiorkowski, david, hscs, fetal, calcium, localization, development, mouse, vivo, microenvironment,
Topics {βοΈ}
nature portfolio privacy policy stem cell research permissions reprints transmembrane-spanning calcium-sensing receptor d-galactose-induced aging model advertising nature cell biol nanoparticle research cation-sensing receptor-deficient mice social media nature genet nature med early g1-phase inhibitor extracellular calcium-sensing receptor nature 425 nature 415 nature nature 439 sca-1+lin- cells fractionated lin-c-kit+sca-1+ calcium-sensing receptor gregor membrane biology program personal data dartmouth-hitchcock medical center author correspondence hsc-enriched endosteal surface permissions information hematopoietic stem cells data protection calcium-sensing receptor springerlink instant access haematopoietic stem cells marrow development stem cell lodgment stem cell niches stem cell engraftment extracellular matrix protein bone morphogenetic protein real time pcr primitive haematopoietic cells lin-c-kit+ cell cycle status competing financial interests privacy extracellular calcium elicits cell tissue kinet permissions hematopoietic microenvironment dartmouth medical school
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
description:Haematopoietic stem cells Γ’ΒΒhomeΓ’ΒΒ to the bone marrow during embryogenesis and after bone marrow transplants. With the exception of integrins, the molecules that mediate this process are largely unknown. Now Adams et al. have identified another factor essential for homing, a membrane-spanning molecule called calcium-sensing receptor (CaR). Cells lacking CaR divide normally, but the newly formed cells are unable to migrate and home to the bone marrow. This newly recognized participant in the localization and engraftment of stem cells provides a potential target for affecting that process. During mammalian ontogeny, haematopoietic stem cells (HSCs) translocate from the fetal liver to the bone marrow, where haematopoiesis occurs throughout adulthood1. Unique features of bone that contribute to a microenvironmental niche for stem cells might include the known high concentration of calcium ions at the HSC-enriched endosteal surface. Cells respond to extracellular ionic calcium concentrations through the seven-transmembrane-spanning calcium-sensing receptor (CaR), which we identified as being expressed on HSCs. Here we show that, through the CaR, the simple ionic mineral content of the niche may dictate the preferential localization of adult mammalian haematopoiesis in bone. Antenatal mice deficient in CaR had primitive haematopoietic cells in the circulation and spleen, whereas few were found in bone marrow. CaR-/- HSCs from fetal liver were normal in number, in proliferative and differentiative function, and in migration and homing to the bone marrow. Yet they were highly defective in localizing anatomically to the endosteal niche, behaviour that correlated with defective adhesion to the extracellular matrix protein, collagen I. CaR has a function in retaining HSCs in close physical proximity to the endosteal surface and the regulatory niche components associated with it.
datePublished:2005-12-28T00:00:00Z
dateModified:2005-12-28T00:00:00Z
pageStart:599
pageEnd:603
sameAs:https://doi.org/10.1038/nature04247
keywords:
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig4_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:439
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Gregor B. Adams
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Karissa T. Chabner
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Ian R. Alley
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Douglas P. Olson
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
type:Person
name:Zbigniew M. Szczepiorkowski
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Massachusetts General Hospital, Harvard Medical School
address:
name:Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dartmouth Medical School
address:
name:Department of Pathology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, USA
type:PostalAddress
type:Organization
type:Person
name:Mark C. Poznansky
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
type:Person
name:Claudine H. Kos
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Martin R. Pollak
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Edward M. Brown
affiliation:
name:Brigham and Women's Hospital, Harvard Medical School
address:
name:Endocrine-Hypertension Division, Membrane Biology Program, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:David T. Scadden
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
description:Haematopoietic stem cells Γ’ΒΒhomeΓ’ΒΒ to the bone marrow during embryogenesis and after bone marrow transplants. With the exception of integrins, the molecules that mediate this process are largely unknown. Now Adams et al. have identified another factor essential for homing, a membrane-spanning molecule called calcium-sensing receptor (CaR). Cells lacking CaR divide normally, but the newly formed cells are unable to migrate and home to the bone marrow. This newly recognized participant in the localization and engraftment of stem cells provides a potential target for affecting that process. During mammalian ontogeny, haematopoietic stem cells (HSCs) translocate from the fetal liver to the bone marrow, where haematopoiesis occurs throughout adulthood1. Unique features of bone that contribute to a microenvironmental niche for stem cells might include the known high concentration of calcium ions at the HSC-enriched endosteal surface. Cells respond to extracellular ionic calcium concentrations through the seven-transmembrane-spanning calcium-sensing receptor (CaR), which we identified as being expressed on HSCs. Here we show that, through the CaR, the simple ionic mineral content of the niche may dictate the preferential localization of adult mammalian haematopoiesis in bone. Antenatal mice deficient in CaR had primitive haematopoietic cells in the circulation and spleen, whereas few were found in bone marrow. CaR-/- HSCs from fetal liver were normal in number, in proliferative and differentiative function, and in migration and homing to the bone marrow. Yet they were highly defective in localizing anatomically to the endosteal niche, behaviour that correlated with defective adhesion to the extracellular matrix protein, collagen I. CaR has a function in retaining HSCs in close physical proximity to the endosteal surface and the regulatory niche components associated with it.
datePublished:2005-12-28T00:00:00Z
dateModified:2005-12-28T00:00:00Z
pageStart:599
pageEnd:603
sameAs:https://doi.org/10.1038/nature04247
keywords:
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_Article_BFnature04247_Fig4_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:439
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Gregor B. Adams
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Karissa T. Chabner
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Ian R. Alley
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
type:Person
name:Douglas P. Olson
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
type:Person
name:Zbigniew M. Szczepiorkowski
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Massachusetts General Hospital, Harvard Medical School
address:
name:Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dartmouth Medical School
address:
name:Department of Pathology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, USA
type:PostalAddress
type:Organization
type:Person
name:Mark C. Poznansky
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
type:Person
name:Claudine H. Kos
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Martin R. Pollak
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Edward M. Brown
affiliation:
name:Brigham and Women's Hospital, Harvard Medical School
address:
name:Endocrine-Hypertension Division, Membrane Biology Program, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:David T. Scadden
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:439
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Massachusetts General Hospital, Harvard Medical School
address:
name:Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
name:Dartmouth Medical School
address:
name:Department of Pathology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, USA
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
name:Brigham and Women's Hospital, Harvard Medical School
address:
name:Endocrine-Hypertension Division, Membrane Biology Program, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Gregor B. Adams
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
name:Karissa T. Chabner
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
name:Ian R. Alley
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
name:Douglas P. Olson
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Zbigniew M. Szczepiorkowski
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Massachusetts General Hospital, Harvard Medical School
address:
name:Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dartmouth Medical School
address:
name:Department of Pathology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, USA
type:PostalAddress
type:Organization
name:Mark C. Poznansky
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Claudine H. Kos
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
name:Martin R. Pollak
affiliation:
name:Renal Division
address:
name:Renal Division, Boston, USA
type:PostalAddress
type:Organization
name:Edward M. Brown
affiliation:
name:Brigham and Women's Hospital, Harvard Medical School
address:
name:Endocrine-Hypertension Division, Membrane Biology Program, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:David T. Scadden
affiliation:
name:Center for Regenerative Medicine
address:
name:Center for Regenerative Medicine,
type:PostalAddress
type:Organization
name:Harvard University
address:
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Center for Regenerative Medicine,
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
name:Center for Regenerative Medicine,
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
name:Center for Regenerative Medicine,
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
name:Center for Regenerative Medicine,
name:Center for Regenerative Medicine,
name:Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA
name:Department of Pathology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, USA
name:Center for Regenerative Medicine,
name:Renal Division, Boston, USA
name:Renal Division, Boston, USA
name:Endocrine-Hypertension Division, Membrane Biology Program, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
name:Center for Regenerative Medicine,
name:Harvard Stem Cell Institute, Harvard University, Cambridge, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {π}(90)
- How much revenue does https://link.springer.com/article/10.1038/nature04247?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle produce monthly?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1912596
- Income figures for http://scholar.google.com/scholar_lookup?&title=Embryonic%20and%20fetal%20hemopoiesis%3A%20an%20overview&journal=Blood%20Cells&volume=17&pages=269-281&publication_year=1991&author=Tavassoli%2CM
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1131427
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=The%20relative%20spatial%20distributions%20of%20CFUs%20and%20CFUc%20in%20the%20normal%20mouse%20femur&journal=Blood&volume=46&pages=65-72&publication_year=1975&author=Lord%2CBI&author=Testa%2CNG&author=Hendry%2CJH have monthly?
- https://doi.org/10.1126%2Fscience.75570's total income per month
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1978Sci...199.1443G gross monthly?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Endosteal%20marrow%3A%20a%20rich%20source%20of%20hematopoietic%20stem%20cells&journal=Science&doi=10.1126%2Fscience.75570&volume=199&pages=1443-1445&publication_year=1978&author=Gong%2CJK?
- How much cash flow does https://doi.org/10.1182%2Fblood.V97.8.2293 have monthly?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Spatial%20localization%20of%20transplanted%20hemopoietic%20stem%20cells%3A%20inferences%20for%20the%20localization%20of%20stem%20cell%20niches&journal=Blood&doi=10.1182%2Fblood.V97.8.2293&volume=97&pages=2293-2299&publication_year=2001&author=Nilsson%2CSK&author=Johnston%2CHM&author=Coverdale%2CJA?
- https://doi.org/10.1016%2FS8756-3282%2895%2900264-2 income
- How much income does http://scholar.google.com/scholar_lookup?&title=Marrow%20development%20and%20its%20relationship%20to%20bone%20formation%20in%20vivo%3A%20a%20histological%20study%20using%20an%20implantable%20titanium%20device%20in%20rabbits&journal=Bone&doi=10.1016%2FS8756-3282%2895%2900264-2&volume=17&pages=407-415&publication_year=1995&author=Zhou%2CH have?
- Earnings of https://doi.org/10.1006%2Fbbrc.1999.0163
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Excessive%20extramedullary%20hematopoiesis%20in%20Cbfa1-deficient%20mice%20with%20a%20congenital%20lack%20of%20bone%20marrow&journal=Biochem.%20Biophys.%20Res.%20Commun.&doi=10.1006%2Fbbrc.1999.0163&volume=255&pages=352-359&publication_year=1999&author=Deguchi%2CK
- What's https://doi.org/10.1016%2FS0002-9440%2810%2961152-2's gross income?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Linking%20hematopoiesis%20to%20endochondral%20skeletogenesis%20through%20analysis%20of%20mice%20transgenic%20for%20collagen%20X&journal=Am.%20J.%20Pathol.&doi=10.1016%2FS0002-9440%2810%2961152-2&volume=160&pages=2019-2034&publication_year=2002&author=Jacenko%2CO?
- What's the monthly income of https://doi.org/10.1038%2Fnature02040?
- Revenue of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003Natur.425..841C
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Osteoblastic%20cells%20regulate%20the%20haematopoietic%20stem%20cell%20niche&journal=Nature&doi=10.1038%2Fnature02040&volume=425&pages=841-846&publication_year=2003&author=Calvi%2CLM generate?
- Learn about the earnings of https://doi.org/10.1038%2Fnature02041
- How much profit does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003Natur.425..836Z make?
- What's http://scholar.google.com/scholar_lookup?&title=Identification%20of%20the%20haematopoietic%20stem%20cell%20niche%20and%20control%20of%20the%20niche%20size&journal=Nature&doi=10.1038%2Fnature02041&volume=415&pages=836-841&publication_year=2003&author=Zhang%2CJ's gross income?
- What's the revenue for https://doi.org/10.1016%2F0014-4827%2888%2990191-7?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Microelectrode%20studies%20on%20the%20acid%20microenvironment%20beneath%20adherent%20macrophages%20and%20osteoclasts&journal=Exp.%20Cell%20Res.&doi=10.1016%2F0014-4827%2888%2990191-7&volume=175&pages=266-276&publication_year=1988&author=Silver%2CIA&author=Murrills%2CRJ&author=Etherington%2CDJ
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9377470
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Calcium-sensing%20receptor%3A%20roles%20in%20and%20beyond%20systemic%20calcium%20homeostasis&journal=Biol.%20Chem.&volume=378&pages=759-768&publication_year=1997&author=Chattopadhyay%2CN&author=Vassilev%2CPM&author=Brown%2CEM produce monthly?
- What is the monthly revenue of https://doi.org/10.1359%2Fjbmr.1997.12.12.1959?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Expression%20of%20an%20extracellular%20calcium-sensing%20receptor%20in%20human%20and%20mouse%20bone%20marrow%20cells&journal=J.%20Bone%20Miner.%20Res.&doi=10.1359%2Fjbmr.1997.12.12.1959&volume=12&pages=1959-1970&publication_year=1997&author=House%2CMG
- Monthly income for https://doi.org/10.1172%2FJCI9799
- How much does http://scholar.google.com/scholar_lookup?&title=Extracellular%20calcium%20elicits%20a%20chemokinetic%20response%20from%20monocytes%20in%20vitro%20and%20in%20vivo&journal=J.%20Clin.%20Invest.&doi=10.1172%2FJCI9799&volume=105&pages=1299-1305&publication_year=2000&author=Olszak%2CIT generate monthly?
- Learn about the earnings of https://doi.org/10.1038%2Fng1295-389
- See how much http://scholar.google.com/scholar_lookup?&title=A%20mouse%20model%20of%20human%20familial%20hypocalciuric%20hypercalcemia%20and%20neonatal%20severe%20hyperparathyroidism&journal=Nature%20Genet.&doi=10.1038%2Fng1295-389&volume=11&pages=389-394&publication_year=1995&author=Ho%2CC makes per month
- What is the earnings of https://doi.org/10.1210%2Fendo.142.9.8364?
- How much money does http://scholar.google.com/scholar_lookup?&title=Rickets%20in%20cation-sensing%20receptor-deficient%20mice%3A%20an%20unexpected%20skeletal%20phenotype&journal=Endocrinology&doi=10.1210%2Fendo.142.9.8364&volume=142&pages=3996-4005&publication_year=2001&author=Garner%2CSC&author=Pi%2CM&author=Tu%2CQ&author=Quarles%2CLD make?
- How much profit does https://doi.org/10.1073%2Fpnas.87.9.3584 generate?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1990PNAS...87.3584S generate monthly?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Functional%20characterization%20of%20individual%20human%20hematopoietic%20stem%20cells%20cultured%20at%20limiting%20dilution%20on%20supportive%20marrow%20stromal%20layers&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.87.9.3584&volume=87&pages=3584-3588&publication_year=1990&author=Sutherland%2CHJ&author=Lansdorp%2CPM&author=Henkelman%2CD&author=Eaves%2CAC&author=Eaves%2CCJ?
- Get to know https://doi.org/10.1038%2Fncb1126's earnings
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=In%20vivo%20self-renewing%20divisions%20of%20haematopoietic%20stem%20cells%20are%20increased%20in%20the%20absence%20of%20the%20early%20G1-phase%20inhibitor%2C%20p18INK4C&journal=Nature%20Cell%20Biol.&doi=10.1038%2Fncb1126&volume=6&pages=436-442&publication_year=2004&author=Yuan%2CY&author=Shen%2CH&author=Franklin%2CDS&author=Scadden%2CDT&author=Cheng%2CT each month?
- Get to know https://doi.org/10.1126%2Fscience.287.5459.1804's earnings
- What's the financial intake of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2000Sci...287.1804C?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Hematopoietic%20stem%20cell%20quiescence%20maintained%20by%20p21cip1%2Fwaf1&journal=Science&doi=10.1126%2Fscience.287.5459.1804&volume=287&pages=1804-1808&publication_year=2000&author=Cheng%2CT
- Income figures for https://doi.org/10.1038%2F81335
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Stem%20cell%20repopulation%20efficiency%20but%20not%20pool%20size%20is%20governed%20by%20p27kip1&journal=Nature%20Med.&doi=10.1038%2F81335&volume=6&pages=1235-1240&publication_year=2000&author=Cheng%2CT&author=Rodrigues%2CN&author=Dombkowski%2CD&author=Stier%2CS&author=Scadden%2CDT?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10942381 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Homing%20and%20engraftment%20potential%20of%20Sca-1%2Blin-%20cells%20fractionated%20on%20the%20basis%20of%20adhesion%20molecule%20expression%20and%20position%20in%20cell%20cycle&journal=Blood&volume=96&pages=1380-1387&publication_year=2000&author=Orschell-Traycoff%2CCM produce monthly?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=4589694
- How much income is http://scholar.google.com/scholar_lookup?&title=Dissecting%20the%20hematopoietic%20microenvironment.%20I.%20Stem%20cell%20lodgment%20and%20commitment%2C%20and%20the%20proliferation%20and%20differentiation%20of%20erythropoietic%20descendants%20in%20the%20Sl%2FSld%20mouse&journal=Cell%20Tissue%20Kinet.&volume=7&pages=89-98&publication_year=1974&author=Wolf%2CNS earning monthly?
- How much revenue does https://doi.org/10.1177%2F002215549804600311 produce monthly?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Immunofluorescence%20charaterization%20of%20key%20extracellular%20matrix%20proteins%20in%20murine%20bone%20marrow%20in%20situ&journal=J.%20Histochem.%20Cytochem.&doi=10.1177%2F002215549804600311&volume=46&pages=371-377&publication_year=1998&author=Nilsson%2CSK earns monthly
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7994060 making per month?
- How much does http://scholar.google.com/scholar_lookup?&title=Development%20of%20hemopoietic%20bone%20marrow%20within%20the%20ectopic%20bone%20induced%20by%20bone%20morphogenetic%20protein&journal=Blood%20Cells&volume=20&pages=191-199&publication_year=1994&author=Kawai%2CM pull in?
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8647226
- How much profit does http://scholar.google.com/scholar_lookup?&title=Recombinant%20human%20bone%20morphogenetic%20protein-2%20induces%20a%20hematopoietic%20microenvironment%20in%20the%20rat%20that%20supports%20the%20growth%20of%20stem%20cells&journal=Exp.%20Hematol.&volume=24&pages=768-775&publication_year=1996&author=An%2CJ&author=Rosen%2CV&author=Cox%2CK&author=Beauchemin%2CN&author=Sullivan%2CAK make?
- Profit of https://doi.org/10.1182%2Fblood.V99.7.2369
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Notch1%20activation%20increases%20hematopoietic%20stem%20cell%20self-renewal%20in%20vivo%20and%20favors%20lymphoid%20over%20myeloid%20lineage%20outcome&journal=Blood&doi=10.1182%2Fblood.V99.7.2369&volume=99&pages=2369-2378&publication_year=2002&author=Stier%2CS&author=Cheng%2CT&author=Dombkowski%2CD&author=Carlesso%2CN&author=Scadden%2CDT
- What are the earnings of https://citation-needed.springer.com/v2/references/10.1038/nature04247?format=refman&flavour=references?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gregor%20B.%20Adams income
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gregor%20B.%20Adams%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Karissa%20T.%20Chabner each month?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Karissa%20T.%20Chabner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ian%20R.%20Alley pull in monthly?
- Monthly income for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ian%20R.%20Alley%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Douglas%20P.%20Olson make?
- Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Douglas%20P.%20Olson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Zbigniew%20M.%20Szczepiorkowski
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Zbigniew%20M.%20Szczepiorkowski%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mark%20C.%20Poznansky generate monthly?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mark%20C.%20Poznansky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Claudine%20H.%20Kos make?
- What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Claudine%20H.%20Kos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Martin%20R.%20Pollak?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Martin%20R.%20Pollak%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Edward%20M.%20Brown bring in each month?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Edward%20M.%20Brown%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=David%20T.%20Scadden
- What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22David%20T.%20Scadden%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_BFnature04247_MOESM1_ESM.pdf earn?
- See how much https://static-content.springer.com/esm/art%3A10.1038%2Fnature04247/MediaObjects/41586_2006_BFnature04247_MOESM2_ESM.pdf makes per month
- Earnings of https://s100.copyright.com/AppDispatchServlet?title=Stem%20cell%20engraftment%20at%20the%20endosteal%20niche%20is%20specified%20by%20the%20calcium-sensing%20receptor&author=Gregor%20B.%20Adams%20et%20al&contentID=10.1038%2Fnature04247©right=Springer%20Nature%20Limited&publication=0028-0836&publicationDate=2005-12-28&publisherName=SpringerNature&orderBeanReset=true
- Learn how profitable https://citation-needed.springer.com/v2/references/10.1038/nature04247?format=refman&flavour=citation is on a monthly basis
- How profitable is https://doi.org/10.1038/s41413-023-00249-w?
- Check the income stats for https://doi.org/10.1038/s41467-023-41770-0
- https://doi.org/10.1007/s00109-023-02315-6's financial summary
- What's the monthly money flow for https://doi.org/10.1007/s11033-022-07898-w?
- What's the revenue for https://doi.org/10.1007/s11051-022-05654-6?
- How much does https://www.protocols.io/ pull in monthly?
- Learn how profitable https://www.natureindex.com/ is on a monthly basis
- How much does http://www.naturechina.com gross monthly?
- What are the total earnings of https://www.natureasia.com/ja-jp?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref