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NATURE . COM {}

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  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
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We are analyzing https://www.nature.com/articles/nature03205.

Title:
Regulation of cap-dependent translation by eIF4E inhibitory proteins | Nature
Description:
Eukaryotic messenger RNAs contain a modified guanosine, termed a cap, at their 5′ ends. Translation of mRNAs requires the binding of an initiation factor, eIF4E, to the cap structure. Here, we describe a family of proteins that through a shared sequence regulate cap-dependent translation. The biological importance of this translational regulation is immense, and affects such processes as cell growth, development, oncogenic transformation and perhaps even axon pathfinding and memory consolidation. A living cell only ever expresses a fraction of the genes within its DNA at one time; in eukaryotes, particularly, much of the genome is irrelevant. But even for the messenger RNAs that are synthesized, expression as a protein is not always immediate. They can be held in the cytoplasm, and activated when needed by the binding of the initiation factor eIF4E to the modified guanosine ‘cap’ at their 5′ ends. Joel Richter and Nahum Sonenberg review recent research on this system, which controls processes as diverse as development, cell growth and tumour formation.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Telecommunications
  • Science

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,058 visitors per month in the current month.

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How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,617 monthly online from display advertisements.

Keywords {🔍}

article, scholar, google, cas, nature, translation, cell, eife, protein, sonenberg, factor, initiation, mrna, access, richter, translational, cancer, content, binding, biol, cookies, regulation, capdependent, cap, growth, embo, privacy, proteins, genes, synaptic, research, data, journal, joel, eukaryotic, mrnas, structure, open, cells, rev, complex, ads, synapses, signaling, advertising, information, subscribe, nahum, messenger, requires,

Topics {✒️}

nature portfolio permissions reprints privacy policy health research creb-mediated long-term facilitation advertising eukaryotic initiation factor-4e social media translation factor eif-4γ author information authors nature struct nature med nature rev proline-rich homeodomain protein long-term synaptic plasticity cell cycle-dependent phosphorylation nature 345 nature 428 nature 433 nature author correspondence translational inhibitor 4e-bp1 cap-dependent translation smaug-mediated translational repression personal data springerlink instant access cpeb-mediated cytoplasmic polyadenylation experience-dependent translation data protection permissions 4e-binding protein 4e-binding protein 1 european economic area messenger rnas cap-binding protein initiation factor eif4e intracellular mrna transport development eif4e binding protein eif4e-binding protein international scholar program common motif shared eif4 initiation factors α-camkii mrna αcamkii mrna polyadenylation privacy eif-4f local protein synthesis rate-limiting factor translation complex eif4f

Questions {❓}

  • Does the ribosome translate cancer?
  • Synaptic tagging–who's it?
  • Will mTOR inhibitors make it as cancer drugs?

Schema {🗺️}

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External Links {🔗}(99)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Foundation
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Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
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Name Servers:

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CDN Services {📦}

  • Crossref

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