
NATURE . COM {
}
Title:
Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein | Nature
Description:
Ethylene gas is used as a hormone by plants, in which it acts as a critical growth regulator. Its synthesis is also rapidly evoked in response to a variety of biotic and abiotic stresses1,2. The Arabidopsis ethylene-overproducer mutants eto2 and eto3 have previously been identified as having mutations in two genes, ACS5 and ACS9, respectively; these encode isozymes of 1-aminocyclopropane-1-carboxylic acid synthase (ACS), which catalyse the rate-limiting step in ethylene biosynthesis3,4. Here we report that another ethylene-overproducer mutation, eto1, is in a gene that negatively regulates ACS activity and ethylene production. The ETO1 protein directly interacts with and inhibits the enzyme activity of full-length ACS5 but not of a truncated form of the enzyme, resulting in a marked accumulation of ACS5 protein and ethylene. Overexpression of ETO1 inhibited induction of ethylene production by the plant growth regulator cytokinin, and promoted ACS5 degradation by a proteasome-dependent pathway. ETO1 also interacts with CUL3, a constituent of ubiquitin ligase complexes in which we propose that ETO1 serves as a substrate-specific adaptor protein. ETO1 thus has a dual mechanism, inhibiting ACS enzyme activity and targeting it for protein degradation. This permits rapid modulation of the concentration of ethylene.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Education
- Science
- Telecommunications
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐ Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$536,300 per month
Our calculations suggest that Nature.com earns between $357,503 and $983,134 monthly online from display advertisements.
Keywords {๐}
article, cas, google, scholar, ethylene, nature, plant, arabidopsis, eto, protein, cell, biosynthesis, access, acs, biol, ecker, synthase, ads, research, content, response, cookies, regulation, wang, yoshida, lurin, enzyme, aminocyclopropanecarboxylate, science, privacy, analysis, data, information, gas, hitoshi, claire, gene, pathway, ubiquitin, family, open, mol, usa, kevin, joseph, plants, acid, activity, cul, support,
Topics {โ๏ธ}
nature portfolio permissions reprints privacy policy advertising nature cell biol social media subscribe nature nature 425 nature 402 nature 428 nature rice research 1-aminocyclopropane-1-carboxylate synthase reveals 1-aminocyclopropane-1-carboxylic acid synthase plant development author correspondence identify ethylene-related mutants univector plasmid-fusion system research scfebf1/ebf2-dependent proteolysis springerlink instant access substrate-specific adaptor protein btb/poz domain proteins permissions supplementary data personal data 1-aminocyclopropane-1-carboxylate synthase stress response pathway 1-aminocyclopropane-1-carboxylic acid ethylene gas biosynthesis data protection ethylene-overproducer mutation privacy substrate-specific adaptor shared active sites competing financial interests plant hormone ethylene ethylene precursor acc ethylene signal transduction substrate-specific adaptors ethylene biosynthesis pathway ethylene response pathway explore content subscription content proteasome-dependent pathway arabidopsis gene family putative substrate adaptors ubiquitin ligase complexes modular ubiquitin ligase ubiquitinโproteasome pathway
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein
description:Ethylene gas is used as a hormone by plants, in which it acts as a critical growth regulator. Its synthesis is also rapidly evoked in response to a variety of biotic and abiotic stresses1,2. The Arabidopsis ethylene-overproducer mutants eto2 and eto3 have previously been identified as having mutations in two genes, ACS5 and ACS9, respectively; these encode isozymes of 1-aminocyclopropane-1-carboxylic acid synthase (ACS), which catalyse the rate-limiting step in ethylene biosynthesis3,4. Here we report that another ethylene-overproducer mutation, eto1, is in a gene that negatively regulates ACS activity and ethylene production. The ETO1 protein directly interacts with and inhibits the enzyme activity of full-length ACS5 but not of a truncated form of the enzyme, resulting in a marked accumulation of ACS5 protein and ethylene. Overexpression of ETO1 inhibited induction of ethylene production by the plant growth regulator cytokinin, and promoted ACS5 degradation by a proteasome-dependent pathway. ETO1 also interacts with CUL3, a constituent of ubiquitin ligase complexes in which we propose that ETO1 serves as a substrate-specific adaptor protein. ETO1 thus has a dual mechanism, inhibiting ACS enzyme activity and targeting it for protein degradation. This permits rapid modulation of the concentration of ethylene.
datePublished:
dateModified:
pageStart:945
pageEnd:950
sameAs:https://doi.org/10.1038/nature02516
keywords:
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig4_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:428
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kevin L.-C. Wang
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Hitoshi Yoshida
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
type:Person
name:Claire Lurin
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
type:Person
name:Joseph R. Ecker
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein
description:Ethylene gas is used as a hormone by plants, in which it acts as a critical growth regulator. Its synthesis is also rapidly evoked in response to a variety of biotic and abiotic stresses1,2. The Arabidopsis ethylene-overproducer mutants eto2 and eto3 have previously been identified as having mutations in two genes, ACS5 and ACS9, respectively; these encode isozymes of 1-aminocyclopropane-1-carboxylic acid synthase (ACS), which catalyse the rate-limiting step in ethylene biosynthesis3,4. Here we report that another ethylene-overproducer mutation, eto1, is in a gene that negatively regulates ACS activity and ethylene production. The ETO1 protein directly interacts with and inhibits the enzyme activity of full-length ACS5 but not of a truncated form of the enzyme, resulting in a marked accumulation of ACS5 protein and ethylene. Overexpression of ETO1 inhibited induction of ethylene production by the plant growth regulator cytokinin, and promoted ACS5 degradation by a proteasome-dependent pathway. ETO1 also interacts with CUL3, a constituent of ubiquitin ligase complexes in which we propose that ETO1 serves as a substrate-specific adaptor protein. ETO1 thus has a dual mechanism, inhibiting ACS enzyme activity and targeting it for protein degradation. This permits rapid modulation of the concentration of ethylene.
datePublished:
dateModified:
pageStart:945
pageEnd:950
sameAs:https://doi.org/10.1038/nature02516
keywords:
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_Article_BFnature02516_Fig4_HTML.jpg
isPartOf:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:428
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Kevin L.-C. Wang
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Hitoshi Yoshida
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
type:Person
name:Claire Lurin
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
type:Person
name:Joseph R. Ecker
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature
issn:
1476-4687
0028-0836
volumeNumber:428
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Kevin L.-C. Wang
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:Hitoshi Yoshida
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
name:Claire Lurin
affiliation:
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
name:National Agricultural Research Center
address:
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
type:PostalAddress
type:Organization
name:INRA-URGV
address:
name:INRA-URGV, Evry cedex, France
type:PostalAddress
type:Organization
name:Joseph R. Ecker
affiliation:
name:The Salk Institute for Biological Studies
address:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
type:PostalAddress
type:Organization
name:University of Pennsylvania
address:
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
name:INRA-URGV, Evry cedex, France
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
name:Department of Rice Research, National Agricultural Research Center, Jo-etsu, Niigata, Japan
name:INRA-URGV, Evry cedex, France
name:Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, USA
name:Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {๐}(92)
- What's the monthly money flow for https://link.springer.com/article/10.1038/nature02516?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- How much profit does https://doi.org/10.1146%2Fannurev.pp.44.060193.001435 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Ethylene%20biosynthesis&journal=Annu.%20Rev.%20Plant%20Physiol.%20Plant%20Mol.%20Biol.&doi=10.1146%2Fannurev.pp.44.060193.001435&volume=44&pages=283-307&publication_year=1993&author=Kende%2CH produce monthly?
- What are the earnings of https://doi.org/10.1105%2Ftpc.001768?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Ethylene%20biosynthesis%20and%20signaling%20networks&journal=Plant%20Cell&doi=10.1105%2Ftpc.001768&volume=14&pages=S131-S151&publication_year=2002&author=Wang%2CKL&author=Li%2CH&author=Ecker%2CJR?
- What are the earnings of https://doi.org/10.1073%2Fpnas.95.8.4766?
- http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998PNAS...95.4766V's total income per month
- How much does http://scholar.google.com/scholar_lookup?&title=Recessive%20and%20dominant%20mutations%20in%20the%20ethylene%20biosynthetic%20gene%20ACS5%20of%20Arabidopsis%20confer%20cytokinin%20insensitivity%20and%20ethylene%20overproduction%2C%20respectively&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.95.8.4766&volume=95&pages=4766-4771&publication_year=1998&author=Vogel%2CJP gross monthly?
- What's the monthly money flow for https://doi.org/10.1105%2Ftpc.006882?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=The%20eto1%2C%20eto2%2C%20and%20eto3%20mutations%20and%20cytokinin%20treatment%20increase%20ethylene%20biosynthesis%20in%20Arabidopsis%20by%20increasing%20the%20stability%20of%20ACS%20protein&journal=Plant%20Cell&doi=10.1105%2Ftpc.006882&volume=15&pages=545-559&publication_year=2003&author=Chae%2CHS&author=Faure%2CF&author=Kieber%2CJJ?
- Find out how much https://doi.org/10.1146%2Fannurev.pp.35.060184.001103 earns monthly
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Ethylene%20biosynthesis%20and%20its%20regulation%20in%20higher%20plants&journal=Annu.%20Rev.%20Plant%20Physiol.%20Plant%20Mol.%20Biol.&doi=10.1146%2Fannurev.pp.35.060184.001103&volume=35&pages=155-189&publication_year=1984&author=Yang%2CSF&author=Hoffman%2CNE is on a monthly basis
- What is the earnings of https://doi.org/10.1146%2Fannurev.cellbio.16.1.1?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Ethylene%3A%20a%20gaseous%20signal%20molecule%20in%20plants&journal=Annu.%20Rev.%20Cell%20Dev.%20Biol.&doi=10.1146%2Fannurev.cellbio.16.1.1&volume=16&pages=1-18&publication_year=2000&author=Bleecker%2CAB&author=Kende%2CH?
- How much revenue does https://doi.org/10.1104%2Fpp.106.2.529 bring in?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=The%20apparent%20turnover%20of%201-aminocyclopropane-1-carboxylate%20synthase%20in%20tomato%20cells%20is%20regulated%20by%20protein%20phosphorylation%20and%20dephosphorylation&journal=Plant%20Physiol.&doi=10.1104%2Fpp.106.2.529&volume=106&pages=529-535&publication_year=1994&author=Spanu%2CP?
- How much does https://doi.org/10.1105%2Ftpc.2.6.513 make?
- How much money does http://scholar.google.com/scholar_lookup?&title=Exploiting%20the%20triple%20response%20of%20Arabidopsis%20to%20identify%20ethylene-related%20mutants&journal=Plant%20Cell&doi=10.1105%2Ftpc.2.6.513&volume=2&pages=513-523&publication_year=1990&author=Guzman%2CP&author=Ecker%2CJR generate?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7768447
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1206465 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20analysis%20of%20ethylene%20signal%20transduction%20in%20Arabidopsis%20thaliana%3A%20five%20novel%20mutant%20loci%20integrated%20into%20a%20stress%20response%20pathway&journal=Genetics&volume=139&pages=1393-1409&publication_year=1995&author=Roman%2CG bring in each month?
- https://doi.org/10.1016%2F0092-8674%2893%2990119-B income
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=CTR1%2C%20a%20negative%20regulator%20of%20the%20ethylene%20response%20pathway%20in%20Arabidopsis%2C%20encodes%20a%20member%20of%20the%20raf%20family%20of%20protein%20kinases&journal=Cell&doi=10.1016%2F0092-8674%2893%2990119-B&volume=72&pages=427-441&publication_year=1993&author=Kieber%2CJJ?
- How much does https://doi.org/10.1016%2Fj.tibs.2003.10.007 generate monthly?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=TPR%20proteins%3A%20the%20versatile%20helix&journal=Trends%20Biochem.&doi=10.1016%2Fj.tibs.2003.10.007&volume=28&pages=655-662&publication_year=2003&author=D%27Andrea%2CLD&author=Regan%2CL?
- What is the monthly revenue of https://doi.org/10.1128%2FMCB.21.11.3609-3615.2001?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=All%20in%20the%20family%3A%20the%20BTB%2FPOZ%2C%20KRAB%2C%20and%20SCAN%20domains&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.21.11.3609-3615.2001&volume=21&pages=3609-3615&publication_year=2001&author=Collins%2CT&author=Stone%2CJR&author=Williams%2CAJ
- How much income does https://doi.org/10.1016%2F0003-2697%2879%2990123-4 have?
- Get to know http://scholar.google.com/scholar_lookup?&title=A%20simple%20and%20sensitive%20assay%20for%201-aminocyclopropane-1-carboxylic%20acid&journal=Anal.%20Biochem.&doi=10.1016%2F0003-2697%2879%2990123-4&volume=100&pages=140-145&publication_year=1979&author=Lizada%2CMC&author=Yang%2CSF's earnings
- How much profit is https://doi.org/10.1073%2Fpnas.95.17.9796 making per month?
- What's the profit of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998PNAS...95.9796T?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Random%20mutagenesis%20of%201-aminocyclopropane-1-carboxylate%20synthase%3A%20a%20key%20enzyme%20in%20ethylene%20biosynthesis&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.95.17.9796&volume=95&pages=9796-9801&publication_year=1998&author=Tarun%2CAS&author=Lee%2CJS&author=Theologis%2CA bring in?
- How much income does https://doi.org/10.1073%2Fpnas.0308515101 have?
- See how much http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2004PNAS..101.2275T makes per month
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Heterodimeric%20interactions%20among%20the%201-amino-cyclopropane-1-carboxylate%20synthase%20polypeptides%20encoded%20by%20the%20Arabidopsis%20gene%20family&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0308515101&volume=101&pages=2275-2280&publication_year=2004&author=Tsuchisaka%2CA&author=Theologis%2CA
- Financial intake of https://doi.org/10.1146%2Fannurev.biochem.67.1.425
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20ubiquitin%20system&journal=Annu.%20Rev.%20Biochem.&doi=10.1146%2Fannurev.biochem.67.1.425&volume=67&pages=425-479&publication_year=1998&author=Hershko%2CA&author=Ciechanover%2CA generate?
- https://doi.org/10.1126%2Fscience.1072831's financial summary
- Get to know http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2002Sci...297..793H's earnings
- How much money does http://scholar.google.com/scholar_lookup?&title=Plant%20development%3A%20regulation%20by%20protein%20degradation&journal=Science&doi=10.1126%2Fscience.1072831&volume=297&pages=793-797&publication_year=2002&author=Hellmann%2CH&author=Estelle%2CM generate?
- Revenue of https://doi.org/10.1038%2Fnature01985
- See how much http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003Natur.425..316X makes per month
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=BTB%20proteins%20are%20substrate-specific%20adaptors%20in%20an%20SCF-like%20modular%20ubiquitin%20ligase%20containing%20CUL-3&journal=Nature&doi=10.1038%2Fnature01985&volume=425&pages=316-321&publication_year=2003&author=Xu%2CL have monthly?
- How much money does https://doi.org/10.1038%2Fnature01959 make?
- What's http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003Natur.425..311P's gross income?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=The%20BTB%20protein%20MEL-26%20is%20a%20substrate-specific%20adaptor%20of%20the%20CUL-3%20ubiquitin-ligase&journal=Nature&doi=10.1038%2Fnature01959&volume=425&pages=311-316&publication_year=2003&author=Pintard%2CL?
- https://doi.org/10.1016%2FS1097-2765%2803%2900341-1's total income per month
- How much does http://scholar.google.com/scholar_lookup?&title=BTB%2FPOZ%20domain%20proteins%20are%20putative%20substrate%20adaptors%20for%20cullin%203%20ubiquitin%20ligases&journal=Mol.%20Cell&doi=10.1016%2FS1097-2765%2803%2900341-1&volume=12&pages=783-790&publication_year=2003&author=Geyer%2CR earn?
- Learn about the earnings of https://doi.org/10.1038%2Fncb1056
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Targeting%20of%20protein%20ubiquitination%20by%20BTB-Cullin%203-Roc1%20ubiquitin%20ligases&journal=Nature%20Cell%20Biol.&doi=10.1038%2Fncb1056&volume=5&pages=1001-1007&publication_year=2003&author=Furukawa%2CM?
- How much profit does https://doi.org/10.1038%2F46478 generate?
- How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1999Natur.402..373K bring in?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Active%20site-directed%20protein%20regulation&journal=Nature&doi=10.1038%2F46478&volume=402&pages=373-376&publication_year=1999&author=Kobe%2CB&author=Kemp%2CBE produce monthly?
- https://doi.org/10.1006%2Fjmbi.1999.3255's total income per month
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Structure%20of%201-aminocyclopropane-1-carboxylate%20synthase%2C%20a%20key%20enzyme%20in%20the%20biosynthesis%20of%20the%20plant%20hormone%20ethylene&journal=J.%20Mol.%20Biol.&doi=10.1006%2Fjmbi.1999.3255&volume=294&pages=745-756&publication_year=1999&author=Capitani%2CG produce monthly?
- How much income is https://doi.org/10.1074%2Fjbc.273.20.12509 earning monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Complementation%20analysis%20of%20mutants%20of%201-aminocyclopropane-1-carboxylate%20synthase%20reveals%20the%20enzyme%20is%20a%20dimer%20with%20shared%20active%20sites&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.273.20.12509&volume=273&pages=12509-12514&publication_year=1998&author=Tarun%2CAS&author=Theologis%2CA make?
- What's the monthly money flow for https://doi.org/10.1016%2FS0092-8674%2803%2900968-1?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=EIN3-dependent%20regulation%20of%20plant%20ethylene%20hormone%20signaling%20by%20two%20Arabidopsis%20F%20box%20proteins%3A%20EBF1%20and%20EBF2&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900968-1&volume=115&pages=679-689&publication_year=2003&author=Potuschak%2CT?
- What's the profit of https://doi.org/10.1016%2FS0092-8674%2803%2900969-3?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Plant%20responses%20to%20ethylene%20gas%20are%20mediated%20by%20SCFEBF1%2FEBF2-dependent%20proteolysis%20of%20EIN3%20transcription%20factor&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900969-3&volume=115&pages=667-677&publication_year=2003&author=Guo%2CH&author=Ecker%2CJR generate?
- How much does https://doi.org/10.1074%2Fjbc.M101543200 bring in each month?
- Get to know http://scholar.google.com/scholar_lookup?&title=Phosphorylation%20of%20tomato%201-aminocyclopropane-1-carboxylic%20acid%20synthase%2C%20LE-ACS2%2C%20at%20the%20C-terminal%20region&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M101543200&volume=276&pages=28051-28057&publication_year=2001&author=Tatsuki%2CM&author=Mori%2CH's earnings
- How profitable is https://doi.org/10.1074%2Fjbc.M308297200?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Biochemical%20diversity%20among%20the%201-amino-cyclopropane-1-carboxylate%20synthase%20isozymes%20encoded%20by%20the%20Arabidopsis%20gene%20family&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M308297200&volume=278&pages=49102-49112&publication_year=2003&author=Yamagami%2CT each month?
- How much profit does https://doi.org/10.1126%2Fscience.1088305 generate?
- Income figures for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003Sci...302..842Y
- How much income does http://scholar.google.com/scholar_lookup?&title=Empirical%20analysis%20of%20transcriptional%20activity%20in%20the%20Arabidopsis%20genome&journal=Science&doi=10.1126%2Fscience.1088305&volume=302&pages=842-846&publication_year=2003&author=Yamada%2CK have?
- Revenue of https://doi.org/10.1016%2FS0960-9822%2807%2900560-X
- Profit of http://scholar.google.com/scholar_lookup?&title=The%20univector%20plasmid-fusion%20system%2C%20a%20method%20for%20rapid%20construction%20of%20recombinant%20DNA%20without%20restriction%20enzymes&journal=Curr.%20Biol.&doi=10.1016%2FS0960-9822%2807%2900560-X&volume=8&pages=1300-1309&publication_year=1998&author=Liu%2CQ
- https://citation-needed.springer.com/v2/references/10.1038/nature02516?format=refman&flavour=references's revenue stream
- What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kevin%20L.-C.%20Wang?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kevin%20L.-C.%20Wang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hitoshi%20Yoshida making per month?
- What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hitoshi%20Yoshida%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Claire%20Lurin?
- What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Claire%20Lurin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joseph%20R.%20Ecker pull in?
- Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joseph%20R.%20Ecker%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- What's the revenue for https://static-content.springer.com/esm/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_BFnature02516_MOESM1_ESM.doc?
- What's the monthly money flow for https://static-content.springer.com/esm/art%3A10.1038%2Fnature02516/MediaObjects/41586_2004_BFnature02516_MOESM2_ESM.jpg?
- What's the monthly money flow for https://s100.copyright.com/AppDispatchServlet?title=Regulation%20of%20ethylene%20gas%20biosynthesis%20by%20the%20Arabidopsis%20ETO1%20protein&author=Kevin%20L.-C.%20Wang%20et%20al&contentID=10.1038%2Fnature02516©right=Macmillan%20Magazines%20Ltd.&publication=0028-0836&publicationDate=2004-04-29&publisherName=SpringerNature&orderBeanReset=true?
- What's the financial gain of https://citation-needed.springer.com/v2/references/10.1038/nature02516?format=refman&flavour=citation?
- Learn how profitable https://doi.org/10.1007/s00425-022-03872-9 is on a monthly basis
- How much income is https://doi.org/10.1007/s00299-022-02884-9 earning monthly?
- What is the earnings of https://doi.org/10.1038/s41477-020-00833-6?
- https://doi.org/10.1007/s00299-020-02624-x income
- What's https://doi.org/10.1186/s43141-020-00083-1's gross income?
- What are the total earnings of https://www.protocols.io/?
- What's the profit of https://www.natureindex.com/?
- What's the revenue for http://www.naturechina.com?
- Revenue of https://www.natureasia.com/ja-jp
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Foundation
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref