NATURE . COM {}

Matching Content Categories {📚}

• Science
• Health & Fitness
• Fitness & Wellness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.

Keywords {🔍}

article, muscle, cas, google, scholar, nature, skeletal, coactivator, type, access, cell, content, transcriptional, expression, mitochondrial, biol, pgcα, fibre, fibres, mice, slow, pgc, cookies, physiol, usa, medical, texas, privacy, data, biogenesis, gene, open, peroxisome, receptor, mol, department, function, formation, lin, olson, proteins, transgenic, kinase, mef, calcineurin, proliferatoractivated, regulates, control, pathway, center,

Topics {✒️}

peroxisome-proliferator-activated receptor-γ nature portfolio permissions reprints privacy policy fast-fibre-type-specific regulatory elements advertising muscle development social media nature 413 nature 418 nature author information authors regulates mitochondrial biogenesis fibre-type-specific promoters fibre-type-specific transcription metachromatic dye-atpase method insulin-sensitive glucose transporter pgc-1α activates transcription author correspondence calcineurin-dependent pathway pgc-1α transgenic mice activator pgc-1α drives springerlink instant access fibre-type determination activates mitochondrial biogenesis slow-twitch muscle fibres cardiac muscle expression multiple calcium-regulated signals permissions content muscle regulator thermogenic coactivator pgc-1 coactivator pgc-1 cooperates cold-inducible coactivator transcriptional coactivator pgc-1 muscle creatine kinase personal data fibre type conversion regulates contractile mitochondrial content data protection nuclear receptors linked skeletal muscle slow chen-yu zhang privacy myocyte enhancer factor-2 transgenic mice driven generating transgenic mice nuclear signalling networks skeletal muscle results skeletal muscle elizabeth

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
         description:The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not well understood. In addition to the expression of particular myofibrillar proteins, type I (slow-twitch) fibres are much higher in mitochondrial content and are more dependent on oxidative metabolism than type II (fast-twitch) fibres1. We have previously identified a transcriptional co-activator, peroxisome-proliferator-activated receptor-γ co-activator-1 (PGC-1α), which is expressed in several tissues including brown fat and skeletal muscle, and that activates mitochondrial biogenesis and oxidative metabolism2,3,4. We show here that PGC-1α is expressed preferentially in muscle enriched in type I fibres. When PGC-1α is expressed at physiological levels in transgenic mice driven by a muscle creatine kinase (MCK) promoter, a fibre type conversion is observed: muscles normally rich in type II fibres are redder and activate genes of mitochondrial oxidative metabolism. Notably, putative type II muscles from PGC-1α transgenic mice also express proteins characteristic of type I fibres, such as troponin I (slow) and myoglobin, and show a much greater resistance to electrically stimulated fatigue. Using fibre-type-specific promoters, we show in cultured muscle cells that PGC-1α activates transcription in cooperation with Mef2 proteins and serves as a target for calcineurin signalling, which has been implicated in slow fibre gene expression. These data indicate that PGC-1α is a principal factor regulating muscle fibre type determination.
         datePublished:
         dateModified:
         pageStart:797
         pageEnd:801
         sameAs:https://doi.org/10.1038/nature00904
         keywords:
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig3_HTML.jpg
         isPartOf:
            name:Nature
            issn:
               1476-4687
               0028-0836
            volumeNumber:418
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Jiandie Lin
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hai Wu
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Paul T. Tarr
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chen-Yu Zhang
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Zhidan Wu
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Olivier Boss
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Laura F. Michael
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Pere Puigserver
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Eiji Isotani
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Eric N. Olson
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bradford B. Lowell
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Rhonda Bassel-Duby
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bruce M. Spiegelman
               affiliation:
                     name:Harvard Medical School
                     address:
                        name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
      description:The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not well understood. In addition to the expression of particular myofibrillar proteins, type I (slow-twitch) fibres are much higher in mitochondrial content and are more dependent on oxidative metabolism than type II (fast-twitch) fibres1. We have previously identified a transcriptional co-activator, peroxisome-proliferator-activated receptor-γ co-activator-1 (PGC-1α), which is expressed in several tissues including brown fat and skeletal muscle, and that activates mitochondrial biogenesis and oxidative metabolism2,3,4. We show here that PGC-1α is expressed preferentially in muscle enriched in type I fibres. When PGC-1α is expressed at physiological levels in transgenic mice driven by a muscle creatine kinase (MCK) promoter, a fibre type conversion is observed: muscles normally rich in type II fibres are redder and activate genes of mitochondrial oxidative metabolism. Notably, putative type II muscles from PGC-1α transgenic mice also express proteins characteristic of type I fibres, such as troponin I (slow) and myoglobin, and show a much greater resistance to electrically stimulated fatigue. Using fibre-type-specific promoters, we show in cultured muscle cells that PGC-1α activates transcription in cooperation with Mef2 proteins and serves as a target for calcineurin signalling, which has been implicated in slow fibre gene expression. These data indicate that PGC-1α is a principal factor regulating muscle fibre type determination.
      datePublished:
      dateModified:
      pageStart:797
      pageEnd:801
      sameAs:https://doi.org/10.1038/nature00904
      keywords:
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature00904/MediaObjects/41586_2002_Article_BFnature00904_Fig3_HTML.jpg
      isPartOf:
         name:Nature
         issn:
            1476-4687
            0028-0836
         volumeNumber:418
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Jiandie Lin
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hai Wu
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Paul T. Tarr
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chen-Yu Zhang
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Zhidan Wu
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Olivier Boss
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Laura F. Michael
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pere Puigserver
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Eiji Isotani
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Eric N. Olson
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bradford B. Lowell
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rhonda Bassel-Duby
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bruce M. Spiegelman
            affiliation:
                  name:Harvard Medical School
                  address:
                     name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature
      issn:
         1476-4687
         0028-0836
      volumeNumber:418
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Jiandie Lin
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Hai Wu
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Paul T. Tarr
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Chen-Yu Zhang
      affiliation:
            name:Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Zhidan Wu
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Olivier Boss
      affiliation:
            name:Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Laura F. Michael
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Pere Puigserver
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Eiji Isotani
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Eric N. Olson
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Bradford B. Lowell
      affiliation:
            name:Harvard Medical School
            address:
               name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Rhonda Bassel-Duby
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Bruce M. Spiegelman
      affiliation:
            name:Harvard Medical School
            address:
               name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
      name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
      name:Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
      name:Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/Nature
• https://twitter.com/nature

External Links {🔗}(93)

• How much profit is https://link.springer.com/article/10.1038/nature00904?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle making per month?
• How much revenue does https://doi.org/10.1152%2Fphysrev.2000.80.3.1215 generate?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Calcium%20ion%20in%20skeletal%20muscle%3A%20its%20crucial%20role%20for%20muscle%20function%2C%20plasticity%2C%20and%20disease&journal=Physiol.%20Rev.&doi=10.1152%2Fphysrev.2000.80.3.1215&volume=80&pages=1215-1265&publication_year=2000&author=Berchtold%2CMW&author=Brinkmeier%2CH&author=Muntener%2CM make?
• https://doi.org/10.1016%2FS0092-8674%2800%2981410-5's total income per month
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=A%20cold-inducible%20coactivator%20of%20nuclear%20receptors%20linked%20to%20adaptive%20thermogenesis&journal=Cell&doi=10.1016%2FS0092-8674%2800%2981410-5&volume=92&pages=829-839&publication_year=1998&author=Puigserver%2CP
• How much does https://doi.org/10.1016%2FS0092-8674%2800%2980611-X gross monthly?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Mechanisms%20controlling%20mitochondrial%20biogenesis%20and%20respiration%20through%20the%20thermogenic%20coactivator%20PGC-1&journal=Cell&doi=10.1016%2FS0092-8674%2800%2980611-X&volume=98&pages=115-124&publication_year=1999&author=Wu%2CZ generate?
• How much revenue does https://doi.org/10.1128%2FMCB.20.5.1868-1876.2000 bring in?
• Find out how much http://scholar.google.com/scholar_lookup?&title=The%20coactivator%20PGC-1%20cooperates%20with%20peroxisome%20proliferator-activated%20receptor%20%CE%B1%20in%20transcriptional%20control%20of%20nuclear%20genes%20encoding%20mitochondrial%20fatty%20acid%20oxidation%20enzymes&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.20.5.1868-1876.2000&volume=20&pages=1868-1876&publication_year=2000&author=Vega%2CRB&author=Huss%2CJM&author=Kelly%2CDP earns monthly
• How much does https://doi.org/10.1152%2Fphysrev.1991.71.2.541 generate monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Molecular%20and%20cellular%20adaptation%20of%20muscle%20in%20response%20to%20exercise%3A%20perspectives%20of%20various%20models&journal=Physiol.%20Rev.&doi=10.1152%2Fphysrev.1991.71.2.541&volume=71&pages=541-585&publication_year=1991&author=Booth%2CFW&author=Thomason%2CDB gross monthly?
• What's https://doi.org/10.1152%2Fjappl.2001.90.3.1137's gross income?
• How profitable is http://scholar.google.com/scholar_lookup?&title=Contractile%20activity-induced%20mitochondrial%20biogenesis%20in%20skeletal%20muscle&journal=J.%20Appl.%20Physiol.&doi=10.1152%2Fjappl.2001.90.3.1137&volume=90&pages=1137-1157&publication_year=2001&author=Hood%2CDA?
• https://doi.org/10.1152%2Fjappl.1972.33.3.312 income
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Enzyme%20activity%20and%20fibre%20composition%20in%20skeletal%20muscle%20of%20untrained%20and%20trained%20men&journal=J.%20Appl.%20Physiol.&doi=10.1152%2Fjappl.1972.33.3.312&volume=33&pages=312-319&publication_year=1972&author=Gollnick%2CPD?
• What's the financial intake of https://doi.org/10.1002%2F%28SICI%291097-4598%28199611%2919%3A11%3C1469%3A%3AAID-MUS11%3E3.0.CO%3B2-O?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Fast-to-slow%20transformation%20in%20stimulated%20rat%20muscle&journal=Muscle%20Nerve&doi=10.1002%2F%28SICI%291097-4598%28199611%2919%3A11%3C1469%3A%3AAID-MUS11%3E3.0.CO%3B2-O&volume=19&pages=1469-1475&publication_year=1996&author=Jarvis%2CJC?
• Find out how much https://doi.org/10.1101%2Fgad.12.16.2499 earns monthly
• Find out how much http://scholar.google.com/scholar_lookup?&title=A%20calcineurin-dependent%20transcriptional%20pathway%20controls%20skeletal%20muscle%20fibre%20type&journal=Genes%20Dev.&doi=10.1101%2Fgad.12.16.2499&volume=12&pages=2499-2509&publication_year=1998&author=Chin%2CER earns monthly
• What is the monthly revenue of https://doi.org/10.1074%2Fjbc.275.7.4545?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Stimulation%20of%20slow%20skeletal%20muscle%20fibre%20gene%20expression%20by%20calcineurin%20in%20vivo&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.275.7.4545&volume=275&pages=4545-4548&publication_year=2000&author=Naya%2CFJ?
• What is the monthly revenue of https://doi.org/10.1074%2Fjbc.M000430200?
• How much does http://scholar.google.com/scholar_lookup?&title=Calcineurin%20co-regulates%20contractile%20and%20metabolic%20components%20of%20slow%20muscle%20phenotype&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M000430200&volume=275&pages=19653-19660&publication_year=2000&author=Bigard%2CX generate monthly?
• What's the total monthly financial gain of https://doi.org/10.1002%2F%28SICI%291521-1878%28200006%2922%3A6%3C510%3A%3AAID-BIES4%3E3.0.CO%3B2-1?
• How much income does http://scholar.google.com/scholar_lookup?&title=Remodeling%20muscles%20with%20calcineurin&journal=Bioassays&doi=10.1002%2F%28SICI%291521-1878%28200006%2922%3A6%3C510%3A%3AAID-BIES4%3E3.0.CO%3B2-1&volume=22&pages=510-519&publication_year=2000&author=Olson%2CEN&author=Williams%2CRS have?
• Find out how much https://doi.org/10.1172%2FJCI10268 earns monthly
• How much money does http://scholar.google.com/scholar_lookup?&title=Peroxisome%20proliferator-activated%20receptor%20%CE%B3%20coactivator-1%20promotes%20cardiac%20mitochondrial%20biogenesis&journal=J.%20Clin.%20Invest.&doi=10.1172%2FJCI10268&volume=106&pages=847-856&publication_year=2000&author=Lehman%2CJJ generate?
• Financial intake of https://doi.org/10.1038%2F35093050
• http://scholar.google.com/scholar_lookup?&title=Control%20of%20hepatic%20gluconeogenesis%20through%20the%20transcriptional%20coactivator%20PGC-1&journal=Nature&doi=10.1038%2F35093050&volume=413&pages=131-138&publication_year=2001&author=Yoon%2CJC's total income per month
• What's the monthly income of https://doi.org/10.1006%2Fgeno.1999.5977?
• How much money does http://scholar.google.com/scholar_lookup?&title=Human%20peroxisome%20proliferator%20activated%20receptor%20gamma%20coactivator%201%20%28PPARGC1%29%20gene%3A%20cDNA%20sequence%2C%20genomic%20organization%2C%20chromosomal%20localization%2C%20and%20tissue%20expression&journal=Genomics&doi=10.1006%2Fgeno.1999.5977&volume=62&pages=98-102&publication_year=1999&author=Esterbauer%2CH make?
• Explore the financials of https://doi.org/10.1074%2Fjbc.C100631200
• Monthly income for http://scholar.google.com/scholar_lookup?&title=PGC-1%CE%B2%3A%20a%20novel%20PGC-1%20related%20transcription%20coactivator%20associated%20with%20host%20cell%20factor&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.C100631200&volume=277&pages=1645-1648&publication_year=2002&author=Lin%2CJ
• What are the earnings of https://doi.org/10.1128%2FMCB.9.8.3393?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Muscle%20creatine%20kinase%20sequence%20elements%20regulating%20skeletal%20and%20cardiac%20muscle%20expression%20in%20transgenic%20mice&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.9.8.3393&volume=9&pages=3393-3399&publication_year=1989&author=Johnson%2CJE&author=Wold%2CBJ&author=Hauschka%2CSD
• What's the revenue for https://doi.org/10.3109%2F10520299009105613?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=A%20metachromatic%20dye-ATPase%20method%20for%20the%20simultaneous%20identification%20of%20skeletal%20muscle%20fibre%20types%20I%2C%20IIA%2C%20IIB%20and%20IIC&journal=Stain%20Technol.&doi=10.3109%2F10520299009105613&volume=65&pages=231-241&publication_year=1990&author=Ogilvie%2CRW&author=Feeback%2CDL
• Monthly income for https://doi.org/10.1152%2Fajpcell.2001.281.5.C1487
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Functional%20and%20molecular%20adaptations%20in%20skeletal%20muscle%20of%20myoglobin-mutant%20mice&journal=Am.%20J.%20Physiol.%20Cell%20Physiol.&doi=10.1152%2Fajpcell.2001.281.5.C1487&volume=281&pages=C1487-C1494&publication_year=2001&author=Grange%2CRW?
• What's the profit of https://doi.org/10.1093%2Femboj%2F19.9.1963?
• See how much http://scholar.google.com/scholar_lookup?&title=MEF2%20responds%20to%20multiple%20calcium-regulated%20signals%20in%20the%20control%20of%20skeletal%20muscle%20fibre%20type&journal=EMBO%20J.&doi=10.1093%2Femboj%2F19.9.1963&volume=19&pages=1963-1973&publication_year=2000&author=Wu%2CH makes per month
• Learn about the earnings of https://doi.org/10.1093%2Femboj%2F20.22.6414
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Activation%20of%20MEF2%20by%20muscle%20activity%20is%20mediated%20through%20a%20calcineurin-dependent%20pathway&journal=EMBO%20J.&doi=10.1093%2Femboj%2F20.22.6414&volume=20&pages=6414-6423&publication_year=2001&author=Wu%2CH?
• https://doi.org/10.1128%2FMCB.19.1.515's total income per month
• What's the income of http://scholar.google.com/scholar_lookup?&title=Fibre-type-specific%20transcription%20of%20the%20troponin%20I%20slow%20gene%20is%20regulated%20by%20multiple%20elements&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.19.1.515&volume=19&pages=515-525&publication_year=1999&author=Calvo%2CS?
• How much money does https://doi.org/10.1146%2Fannurev.cellbio.14.1.167 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Transcriptional%20control%20of%20muscle%20development%20by%20myocyte%20enhancer%20factor-2%20%28MEF2%29%20proteins&journal=Annu.%20Rev.%20Cell%20Dev.%20Biol.&doi=10.1146%2Fannurev.cellbio.14.1.167&volume=14&pages=167-196&publication_year=1998&author=Black%2CBL&author=Olson%2CEN pull in?
• What's the financial intake of https://doi.org/10.1128%2FMCB.20.17.6600-6611.2000?
• How much does http://scholar.google.com/scholar_lookup?&title=A%20calcineurin-NFATc3-dependent%20pathway%20regulates%20skeletal%20muscle%20differentiation%20and%20slow%20myosin%20heavy-chain%20expression&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.20.17.6600-6611.2000&volume=20&pages=6600-6611&publication_year=2000&author=Delling%2CU make?
• What's the monthly money flow for https://doi.org/10.1073%2Fpnas.061035098?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Restoration%20of%20insulin-sensitive%20glucose%20transporter%20%28Glut4%29%20gene%20expression%20in%20muscle%20cells%20by%20the%20transcriptional%20coactivator%20PGC-1&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.061035098&volume=98&pages=3820-3825&publication_year=2001&author=Michael%2CLF
• Profit of https://doi.org/10.1128%2FMCB.16.5.2408
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Common%20core%20sequences%20are%20found%20in%20skeletal%20muscle%20slow-%20and%20fast-fibre-type-specific%20regulatory%20elements&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.16.5.2408&volume=16&pages=2408-2417&publication_year=1996&author=Nakayama%2CM
• Learn about the earnings of https://doi.org/10.1006%2Fbbrc.2000.3134
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=cDNA%20cloning%20and%20mRNA%20analysis%20of%20PGC-1%20in%20epitrochlearis%20muscle%20in%20swimming-exercised%20rats&journal=Biochem.%20Biophys.%20Res.%20Comm.&doi=10.1006%2Fbbrc.2000.3134&volume=274&pages=350-354&publication_year=2000&author=Goto%2CM?
• How much profit is https://citation-needed.springer.com/v2/references/10.1038/nature00904?format=refman&flavour=references making per month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jiandie%20Lin bring in each month?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jiandie%20Lin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hai%20Wu?
• Earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hai%20Wu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Paul%20T.%20Tarr's revenue stream
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Paul%20T.%20Tarr%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
• Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Chen-Yu%20Zhang
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Chen-Yu%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Zhidan%20Wu
• Earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Zhidan%20Wu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Olivier%20Boss earns monthly
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Olivier%20Boss%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
• Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Laura%20F.%20Michael
• Explore the financials of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Laura%20F.%20Michael%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pere%20Puigserver
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pere%20Puigserver%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eiji%20Isotani each month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eiji%20Isotani%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eric%20N.%20Olson pull in?
• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eric%20N.%20Olson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bradford%20B.%20Lowell?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bradford%20B.%20Lowell%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rhonda%20Bassel-Duby bring in?
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rhonda%20Bassel-Duby%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bruce%20M.%20Spiegelman earning monthly?
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bruce%20M.%20Spiegelman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• How much does https://s100.copyright.com/AppDispatchServlet?title=Transcriptional%20co-activator%20PGC-1%CE%B1%20drives%20the%20formation%20of%20slow-twitch%20muscle%20fibres&author=Jiandie%20Lin%20et%20al&contentID=10.1038%2Fnature00904©right=Macmillan%20Magazines%20Ltd.&publication=0028-0836&publicationDate=2002-08-15&publisherName=SpringerNature&orderBeanReset=true gross monthly?
• Learn about the earnings of https://citation-needed.springer.com/v2/references/10.1038/nature00904?format=refman&flavour=citation
• How much money does https://doi.org/10.1186/s40104-023-00968-4 make?
• What's the total monthly financial gain of https://doi.org/10.1038/s41598-024-52198-x?
• What's the financial gain of https://doi.org/10.1038/s41598-023-50464-y?
• Get to know https://doi.org/10.1007/s40279-024-02007-2's earnings
• Earnings of https://doi.org/10.1186/s13395-023-00327-x
• How much income does https://www.protocols.io/ have?
• Revenue of https://www.natureindex.com/
• What's the revenue for http://www.naturechina.com?
• Learn about the earnings of https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref