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NATURE . COM {}

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  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
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We are analyzing https://www.nature.com/articles/cmi20126.

Title:
Engineering humanized mice for improved hematopoietic reconstitution | Cellular & Molecular Immunology
Description:
Humanized mice are immunodeficient animals engrafted with human hematopoietic stem cells that give rise to various lineages of human blood cells throughout the life of the mouse. This article reviews recent advances in the generation of humanized mice, focusing on practical considerations. We discuss features of different immunodeficient recipient mouse strains, sources of human hematopoietic stem cells, advances in expansion and genetic modification of hematopoietic stem cells, and techniques to modulate the cytokine environment of recipient mice, in order to enhance reconstitution of specific human blood lineage cells. We highlight the opportunities created by new technologies and discuss practical considerations on how to make best use of the widening array of basic models for specific research applications.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Science
  • Education
  • Non-Profit & Charity

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,797,153 visitors per month in the current month.

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How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$539,300 per month
Our analysis indicates Nature.com generates between $359,538 and $988,730 monthly online from display ads.

Keywords {🔍}

pubmed, google, scholar, cas, human, cells, blood, mice, central, stem, cell, hematopoietic, gene, humanized, nature, mouse, development, cord, article, chen, research, expansion, vivo, engraftment, science, ther, access, immunol, expression, usa, therapy, lentiviral, model, immune, nodscid, content, reconstitution, shultz, proc, natl, acad, sci, nat, regulatory, virus, med, transfer, adenoassociated, vectors, mol,

Topics {✒️}

nature portfolio permissions reprints privacy policy nod/ltsz-scid il2rγnull mice granulocyte–macrophage colony-stimulating factor long-term culture-initiating cells nature 2006 nature advertising human il-3/gm-csf knock t-cell-dependent antibody responses social media translational biomedical research specific research applications nod-scid il2rγnull mice long-term cytokine production nod/scid-repopulating cells antigen-presenting cells derived humanized rag2−/−γc−/− mice hla-restricted immune responses integrative cancer research multipotent hematopoietic progenitors immunocompetent scid-hu mice human t-cell reconstitution dna methylation-mediated silencing multiple ets factors nod/scid/γcnull mouse cd34+ac133+ cells isolated patient-derived xenografts eugenia implantable pre-metastatic niches lentivirus-mediated gene therapy human cd4+foxp3+ regulatory cell type-specific manner long-term multilineage engraftment hematopoietic progenitor cells wiskott–aldrich syndrome gene murine bernard-soulier syndrome immunodeficient mouse model—rag2 virus-mediated gene transfer human hematopoietic stem human hematopoietic cells personal data hematopoietic stem cells anti-cd47 antibody synergizes springerlink instant access umbilical cord blood human immune system nod/scid/γcnull nod-scid mouse human immune responses

Questions {❓}

  • Gene therapy: is IL2RG oncogenic in T-cell development?

Schema {🗺️}

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         headline:Engineering humanized mice for improved hematopoietic reconstitution
         description:Humanized mice are immunodeficient animals engrafted with human hematopoietic stem cells that give rise to various lineages of human blood cells throughout the life of the mouse. This article reviews recent advances in the generation of humanized mice, focusing on practical considerations. We discuss features of different immunodeficient recipient mouse strains, sources of human hematopoietic stem cells, advances in expansion and genetic modification of hematopoietic stem cells, and techniques to modulate the cytokine environment of recipient mice, in order to enhance reconstitution of specific human blood lineage cells. We highlight the opportunities created by new technologies and discuss practical considerations on how to make best use of the widening array of basic models for specific research applications.
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      headline:Engineering humanized mice for improved hematopoietic reconstitution
      description:Humanized mice are immunodeficient animals engrafted with human hematopoietic stem cells that give rise to various lineages of human blood cells throughout the life of the mouse. This article reviews recent advances in the generation of humanized mice, focusing on practical considerations. We discuss features of different immunodeficient recipient mouse strains, sources of human hematopoietic stem cells, advances in expansion and genetic modification of hematopoietic stem cells, and techniques to modulate the cytokine environment of recipient mice, in order to enhance reconstitution of specific human blood lineage cells. We highlight the opportunities created by new technologies and discuss practical considerations on how to make best use of the widening array of basic models for specific research applications.
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External Links {🔗}(236)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
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  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

5.17s.