
NATURE . COM {
}
Title:
Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons | Cell Death & Differentiation
Description:
Mitochondrial dysfunction is an underpinning event in many neurodegenerative disorders. Less clear, however, is how mitochondria become injured during neuronal demise. Nitric oxide (NO) evokes rapid mitochondrial fission in cortical neurons. Interestingly, proapoptotic Bax relocates from the cytoplasm into large foci on mitochondrial scission sites in response to nitrosative stress. Antiapoptotic Bcl-xL does not prevent mitochondrial fission despite its ability to block Bax puncta formation on mitochondria and to mitigate neuronal cell death. Mitofusin 1 (Mfn1) or dominant-negative dynamin-related protein 1K38A (Drp1k38A) inhibits mitochondrial fission and Bax accumulation on mitochondria induced by exposure to an NO donor. Although NO is known to cause a bioenergetic crisis, lowering ATP by glycolytic or mitochondrial inhibitors neither induces mitochondrial fission nor Bax foci formation on mitochondria. Taken together, these data indicate that the mitochondrial fission machinery acts upstream of the Bcl-2 family of proteins in neurons challenged with nitrosative stress.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Science
- Telecommunications
- Education
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,555,829 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$536,300 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $357,511 to $983,155.
Keywords {π}
mitochondrial, fission, mitochondria, cell, bax, neurons, snoc, death, article, neuronal, figure, cas, google, scholar, foci, formation, mfn, egfpbax, exposure, cultures, morphology, cortical, stress, bclxl, dsredmito, nitric, nature, nitrosative, drpka, fusion, membrane, number, drp, neuron, oxide, volume, data, image, atp, activation, size, snocinduced, length, min, control, biol, results, effects, images, cells,
Topics {βοΈ}
nature portfolio alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors permissions reprints privacy policy secondary nature nature advertising blocked n-methyl-d-aspartate social media amp-activated protein kinase 1βmg/ml poly-l-lysine n-methyl-d-aspartate antiapoptotic bcl-xl failed dsred2-mito/egfp-bax colocalization dynamin-related protein drp1 pentylenetetrazole-induced clonic seizures cell death-related events charcot-maric-tooth-type2a intracellular power-transmitting cables imaging research greater capillary-fiber interface hepes-buffered salt solution life scientific fisher scientific wolfram research medical research nitric oxide-induced apoptosis nmda receptor-channel complex full size image caspase-independent cell death mitochondrial fission/fusion machinery dynamin-related protein 1 bcl-xl blocks cytochrome ice-cold distilled water egfp-bax pattern changed snoc-induced mitochondrial fission bcl-2 related proteins voltage-gated ca2+ channels adenine nucleotide translocase dynamin-related gtpases nitric oxide production author correspondence plasmids encoding dsred2-mito antiapoptotic bcl-xl fccp-induced mitochondrial shortening dsred2-mito selectively traces high-resolution fluorescence imaging plasmids encoding egfp-bax distinct events induced neurons expressing dsred2-mito
Questions {β}
- A specific method for activating AMP-activated protein kinase in intact cells?
- How does NO evoke mitochondrial fission?
- How does mitochondrial fission lead to neurodegeneration?
- What is the role of mitochondrial fission in the execution program of cell death?
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons
description:Mitochondrial dysfunction is an underpinning event in many neurodegenerative disorders. Less clear, however, is how mitochondria become injured during neuronal demise. Nitric oxide (NO) evokes rapid mitochondrial fission in cortical neurons. Interestingly, proapoptotic Bax relocates from the cytoplasm into large foci on mitochondrial scission sites in response to nitrosative stress. Antiapoptotic Bcl-xL does not prevent mitochondrial fission despite its ability to block Bax puncta formation on mitochondria and to mitigate neuronal cell death. Mitofusin 1 (Mfn1) or dominant-negative dynamin-related protein 1K38A (Drp1k38A) inhibits mitochondrial fission and Bax accumulation on mitochondria induced by exposure to an NO donor. Although NO is known to cause a bioenergetic crisis, lowering ATP by glycolytic or mitochondrial inhibitors neither induces mitochondrial fission nor Bax foci formation on mitochondria. Taken together, these data indicate that the mitochondrial fission machinery acts upstream of the Bcl-2 family of proteins in neurons challenged with nitrosative stress.
datePublished:2006-10-20T00:00:00Z
dateModified:2006-10-20T00:00:00Z
pageStart:462
pageEnd:471
sameAs:https://doi.org/10.1038/sj.cdd.4402046
keywords:
nitric oxide
Bcl-2 family proteins
Drp1
Mfn
neurodegeneration
Life Sciences
general
Biochemistry
Cell Biology
Stem Cells
Apoptosis
Cell Cycle Analysis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig7_HTML.gif
isPartOf:
name:Cell Death & Differentiation
issn:
1476-5403
1350-9047
volumeNumber:14
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:H Yuan
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:A A Gerencser
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:G Liot
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:S A Lipton
affiliation:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:M Ellisman
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:G A Perkins
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:E Bossy-Wetzel
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons
description:Mitochondrial dysfunction is an underpinning event in many neurodegenerative disorders. Less clear, however, is how mitochondria become injured during neuronal demise. Nitric oxide (NO) evokes rapid mitochondrial fission in cortical neurons. Interestingly, proapoptotic Bax relocates from the cytoplasm into large foci on mitochondrial scission sites in response to nitrosative stress. Antiapoptotic Bcl-xL does not prevent mitochondrial fission despite its ability to block Bax puncta formation on mitochondria and to mitigate neuronal cell death. Mitofusin 1 (Mfn1) or dominant-negative dynamin-related protein 1K38A (Drp1k38A) inhibits mitochondrial fission and Bax accumulation on mitochondria induced by exposure to an NO donor. Although NO is known to cause a bioenergetic crisis, lowering ATP by glycolytic or mitochondrial inhibitors neither induces mitochondrial fission nor Bax foci formation on mitochondria. Taken together, these data indicate that the mitochondrial fission machinery acts upstream of the Bcl-2 family of proteins in neurons challenged with nitrosative stress.
datePublished:2006-10-20T00:00:00Z
dateModified:2006-10-20T00:00:00Z
pageStart:462
pageEnd:471
sameAs:https://doi.org/10.1038/sj.cdd.4402046
keywords:
nitric oxide
Bcl-2 family proteins
Drp1
Mfn
neurodegeneration
Life Sciences
general
Biochemistry
Cell Biology
Stem Cells
Apoptosis
Cell Cycle Analysis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.cdd.4402046/MediaObjects/41418_2007_Article_BF4402046_Fig7_HTML.gif
isPartOf:
name:Cell Death & Differentiation
issn:
1476-5403
1350-9047
volumeNumber:14
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:H Yuan
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:A A Gerencser
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:G Liot
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:S A Lipton
affiliation:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:M Ellisman
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:G A Perkins
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
type:Person
name:E Bossy-Wetzel
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Cell Death & Differentiation
issn:
1476-5403
1350-9047
volumeNumber:14
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:H Yuan
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:A A Gerencser
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:G Liot
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:S A Lipton
affiliation:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:M Ellisman
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
name:G A Perkins
affiliation:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego
address:
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
type:PostalAddress
type:Organization
name:E Bossy-Wetzel
affiliation:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research
address:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research
address:
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
name:National Center for Microscopy and Imaging Research, School of Medicine, University of California, San Diego, La Jolla, USA
name:Apoptosis and Cell Death Program, Burnham Institute for Medical Research, La Jolla, USA
name:Center for Neuroscience and Aging, Burnham Institute for Medical Research, La Jolla, USA
External Links {π}(104)
- https://doi.org/10.1126%2Fscience.1079368's total income per month
- How much does http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20biogenesis%20in%20mammals%3A%20the%20role%20of%20endogenous%20nitric%20oxide&journal=Science&doi=10.1126%2Fscience.1079368&volume=299&pages=896-899&publication_year=2003&author=Nisoli%2CE&author=Clementi%2CE&author=Paolucci%2CC&author=Cozzi%2CV&author=Tonello%2CC&author=Sciorati%2CC generate monthly?
- https://doi.org/10.1016%2FS0079-6123%2808%2963210-0's revenue stream
- Get to know http://scholar.google.com/scholar_lookup?&title=TM%20nitric%20oxide%20in%20neurodegeneration&journal=Prog%20Brain%20Res&doi=10.1016%2FS0079-6123%2808%2963210-0&volume=118&pages=215-229&publication_year=1998&author=Dawson%2CVL&author=Dawson%2CTM's earnings
- How much does https://doi.org/10.1073%2Fpnas.92.16.7162 rake in every month?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Apoptosis%20and%20necrosis%3A%20two%20distinct%20events%20induced%2C%20respectively%2C%20by%20mild%20and%20intense%20insults%20with%20N-methyl-D-aspartate%20or%20nitric%20oxide%2Fsuperoxide%20in%20cortical%20cell%20cultures&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.92.16.7162&volume=92&pages=7162-7166&publication_year=1995&author=Bonfoco%2CE&author=Krainc%2CD&author=Ankarcrona%2CM&author=Nicotera%2CP&author=Lipton%2CSA make?
- What's the total monthly financial gain of https://doi.org/10.1016%2Fj.mam.2004.09.004?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Nitric%20oxide%20and%20neurological%20disorders&journal=Mol%20Aspects%20Med&doi=10.1016%2Fj.mam.2004.09.004&volume=26&pages=67-96&publication_year=2005&author=Duncan%2CAJ&author=Heales%2CSJ bring in?
- What's the monthly income of https://doi.org/10.1006%2Fabbi.1994.1013?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20mitochondrial%20electron%20transport%20by%20peroxynitrite&journal=Arch%20Biochem%20Biophys&doi=10.1006%2Fabbi.1994.1013&volume=308&pages=89-95&publication_year=1994&author=Radi%2CR&author=Rodriguez%2CM&author=Castro%2CL&author=Telleri%2CR
- How much revenue does https://doi.org/10.1016%2F0014-5793%2894%2901290-3 bring in?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Nanomolar%20concentrations%20of%20nitric%20oxide%20reversibly%20inhibit%20synaptosomal%20respiration%20by%20competing%20with%20oxygen%20at%20cytochrome%20oxidase&journal=FEBS%20Lett&doi=10.1016%2F0014-5793%2894%2901290-3&volume=356&pages=295-298&publication_year=1994&author=Brown%2CGC&author=Cooper%2CCE
- Revenue of https://doi.org/10.1523%2FJNEUROSCI.19-01-00147.1999
- How much does http://scholar.google.com/scholar_lookup?&title=Nitric%20oxide%20acutely%20inhibits%20neuronal%20energy%20production.%20The%20Committees%20on%20Neurobiology%20and%20Cell%20Physiology&journal=J%20Neurosci&doi=10.1523%2FJNEUROSCI.19-01-00147.1999&volume=19&pages=147-158&publication_year=1999&author=Brorson%2CJR&author=Schumacker%2CPT&author=Zhang%2CH pull in monthly?
- How much does https://doi.org/10.1016%2FS0896-6273%2804%2900015-7 bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Crosstalk%20between%20nitric%20oxide%20and%20zinc%20pathways%20to%20neuronal%20cell%20death%20involving%20mitochondrial%20dysfunction%20and%20p38-activated%20K%2B%20channels&journal=Neuron&doi=10.1016%2FS0896-6273%2804%2900015-7&volume=41&pages=351-365&publication_year=2004&author=Bossy-Wetzel%2CE&author=Talantova%2CMV&author=Lee%2CWD&author=Sch%C3%B6lzke%2CMN&author=Harrop%2CA&author=Mathews%2CE earn?
- Get to know https://doi.org/10.1083%2Fjcb.150.2.335's earnings
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=p38%20MAP%20kinase%20mediates%20bax%20translocation%20in%20nitric%20oxide-induced%20apoptosis%20in%20neurons&journal=J%20Cell%20Biol&doi=10.1083%2Fjcb.150.2.335&volume=150&pages=335-347&publication_year=2000&author=Ghatan%2CS&author=Larner%2CS&author=Kinoshita%2CY&author=Hetman%2CM&author=Patel%2CL&author=Xia%2CZ?
- What's the financial gain of https://doi.org/10.1038%2F13014?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=The%20dynamin-related%20GTPase%20Dnm1%20regulates%20mitochondrial%20fission%20in%20yeast&journal=Nat%20Cell%20Biol&doi=10.1038%2F13014&volume=1&pages=298-304&publication_year=1999&author=Bleazard%2CW&author=McCaffery%2CJM&author=King%2CEJ&author=Bale%2CS&author=Mozdy%2CA&author=Tieu%2CQ?
- How much profit does https://doi.org/10.1091%2Fmbc.12.8.2245 make?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Dynamin-related%20protein%20Drp1%20is%20required%20for%20mitochondrial%20division%20in%20mammalian%20cells&journal=Mol%20Biol%20Cell&doi=10.1091%2Fmbc.12.8.2245&volume=12&pages=2245-2256&publication_year=2001&author=Smirnova%2CE&author=Griparic%2CL&author=Shurland%2CDL&author=van%20der%20Bliek%2CAM?
- What's the total monthly financial gain of https://doi.org/10.1016%2FS1534-5807%2801%2900055-7?
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20dynamin-related%20protein%201%2C%20a%20mediator%20of%20mitochondrial%20fission%2C%20in%20apoptosis&journal=Dev%20Cell&doi=10.1016%2FS1534-5807%2801%2900055-7&volume=1&pages=515-525&publication_year=2001&author=Frank%2CS&author=Gaume%2CB&author=Bergmann-Leitner%2CES&author=Leitner%2CWW&author=Robert%2CEG&author=Catez%2CF?
- What's the revenue for https://doi.org/10.1016%2Fj.cell.2006.06.010?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Mitochondria%3A%20dynamic%20organelles%20in%20disease%2C%20aging%2C%20and%20development&journal=Cell&doi=10.1016%2Fj.cell.2006.06.010&volume=125&pages=1241-1252&publication_year=2006&author=Chan%2CDC make?
- How much profit is https://doi.org/10.1126%2Fscience.1100612 making per month?
- http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20fusion%20intermediates%20revealed%20in%20vitro&journal=Science&doi=10.1126%2Fscience.1100612&volume=305&pages=1747-1752&publication_year=2004&author=Meeusen%2CS&author=McCaffery%2CJM&author=Nunnari%2CJ income
- How much does https://doi.org/10.1074%2Fjbc.M400920200 generate monthly?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Loss%20of%20the%20intermembrane%20space%20protein%20Mgm1%2FOPA1%20induces%20swelling%20and%20localized%20constrictions%20along%20the%20lengths%20of%20mitochondria&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M400920200&volume=279&pages=18792-18798&publication_year=2004&author=Griparic%2CL&author=van%20der%20Wel%2CNN&author=Orozco%2CIJ&author=Peters%2CPJ&author=van%20der%20Bliek%2CAM is on a monthly basis
- What's the financial gain of https://doi.org/10.1074%2Fjbc.M503062200?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Disruption%20of%20fusion%20results%20in%20mitochondrial%20heterogeneity%20and%20dysfunction&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M503062200&volume=280&pages=26185-26192&publication_year=2005&author=Chen%2CH&author=Chomyn%2CA&author=Chan%2CDC?
- How much cash flow does https://doi.org/10.1038%2Fsj.emboj.7601253 have monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Nitric%20oxide-induced%20mitochondrial%20fission%20is%20regulated%20by%20dynamin-related%20GTPases%20in%20neurons&journal=EMBO%20J&doi=10.1038%2Fsj.emboj.7601253&volume=25&pages=3900-3911&publication_year=2006&author=Barsoum%2CMJ&author=Yuan%2CH&author=Gerencser%2CAA&author=Liot%2CG&author=Kushnareva%2CY&author=Graber%2CS make?
- What are the earnings of https://doi.org/10.1091%2Fmbc.e04-04-0294?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Roles%20of%20the%20mammalian%20mitochondrial%20fission%20and%20fusion%20mediators%20Fis1%2C%20Drp1%2C%20and%20Opa1%20in%20apoptosis&journal=Mol%20Biol%20Cell&doi=10.1091%2Fmbc.e04-04-0294&volume=15&pages=5001-5011&publication_year=2004&author=Lee%2CYJ&author=Jeong%2CSY&author=Karbowski%2CM&author=Smith%2CCL&author=Youle%2CRJ?
- What's the total monthly financial gain of https://doi.org/10.1016%2F0896-6273%2892%2990130-6?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Effect%20of%20nitric%20oxide%20production%20on%20the%20redox%20modulatory%20site%20of%20the%20NMDA%20receptor-channel%20complex&journal=Neuron&doi=10.1016%2F0896-6273%2892%2990130-6&volume=8&pages=1087-1099&publication_year=1992&author=Lei%2CSZ&author=Pan%2CZH&author=Aggarwal%2CSK&author=Chen%2CHS&author=Hartman%2CJ&author=Sucher%2CNJ?
- How much profit does https://doi.org/10.1016%2FS0006-8993%2800%2902161-2 make?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Nitric%20oxide%20%28NO%E2%80%A2%29%20stabilizes%20whereas%20nitrosonium%20%28NO%2B%29%20enhances%20filopodial%20outgrowth%20by%20rat%20retinal%20ganglion%20cells%20in%20vitro&journal=Brain%20Res&doi=10.1016%2FS0006-8993%2800%2902161-2&volume=868&pages=1-13&publication_year=2000&author=Cheung%2CWS&author=Bhan%2CI&author=Lipton%2CSA have monthly?
- See how much https://doi.org/10.1083%2Fjcb.139.5.1281 makes per month
- Find out how much http://scholar.google.com/scholar_lookup?&title=Movement%20of%20Bax%20from%20the%20cytosol%20to%20mitochondria%20during%20apoptosis&journal=J%20Cell%20Biol&doi=10.1083%2Fjcb.139.5.1281&volume=139&pages=1281-1292&publication_year=1997&author=Wolter%2CKG&author=Hsu%2CYT&author=Smith%2CCL&author=Nechushtan%2CA&author=Xi%2CXG&author=Youle%2CRJ earns monthly
- How much cash flow does https://doi.org/10.1093%2Femboj%2F18.9.2330 have monthly?
- How much income does http://scholar.google.com/scholar_lookup?&title=Conformation%20of%20the%20Bax%20C-terminus%20regulates%20subcellular%20location%20and%20cell%20death&journal=EMBO%20J&doi=10.1093%2Femboj%2F18.9.2330&volume=18&pages=2330-2341&publication_year=1999&author=Nechushtan%2CA&author=Smith%2CCL&author=Hsu%2CYT&author=Youle%2CRJ have?
- What is the monthly revenue of https://doi.org/10.1016%2FS0092-8674%2804%2900046-7?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Cell%20death%3A%20critical%20control%20points&journal=Cell&doi=10.1016%2FS0092-8674%2804%2900046-7&volume=116&pages=205-219&publication_year=2004&author=Danial%2CNN&author=Korsmeyer%2CSJ bring in?
- Earnings of https://doi.org/10.1016%2FS0014-4886%2803%2900243-7
- See how much http://scholar.google.com/scholar_lookup?&title=Glucose%20deprivation%20produces%20a%20prolonged%20increase%20in%20sensitivity%20to%20glutamate%20in%20cultured%20rat%20cortical%20neurons&journal=Exp%20Neurol&doi=10.1016%2FS0014-4886%2803%2900243-7&volume=183&pages=682-694&publication_year=2003&author=Vergun%2CO&author=Han%2CYY&author=Reynolds%2CIJ makes per month
- What's the income generated by https://doi.org/10.1111%2Fj.1471-4159.1971.tb00013.x each month?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20glyceraldehyde-3-phosphate%20dehydrogenase%20in%20mammalian%20nerve%20by%20iodoacetic%20acid&journal=J%20Neurochem&doi=10.1111%2Fj.1471-4159.1971.tb00013.x&volume=18&pages=1509-1514&publication_year=1971&author=Sabri%2CMI&author=Ochs%2CS?
- Profit of https://doi.org/10.1111%2Fj.1432-1033.1995.tb20498.x
- http://scholar.google.com/scholar_lookup?&title=5-aminoimidazole-4-carboxamide%20ribonucleoside.%20A%20specific%20method%20for%20activating%20AMP-activated%20protein%20kinase%20in%20intact%20cells%3F&journal=Eur%20J%20Biochem&doi=10.1111%2Fj.1432-1033.1995.tb20498.x&volume=229&pages=558-565&publication_year=1995&author=Corton%2CJM&author=Gillespie%2CJG&author=Hawley%2CSA&author=Hardie%2CDG's revenue stream
- Explore the financials of https://doi.org/10.1523%2FJNEUROSCI.1450-05.2005
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20nitric%20oxide%20mediates%20decreased%20vulnerability%20of%20hippocampal%20neurons%20from%20immature%20animals%20to%20NMDA&journal=J%20Neurosci&doi=10.1523%2FJNEUROSCI.1450-05.2005&volume=25&pages=6561-6575&publication_year=2005&author=Marks%2CJD&author=Boriboun%2CC&author=Wang%2CJ?
- How much profit does https://doi.org/10.1038%2F90116 make?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Human%20cells%20are%20protected%20from%20mitochondrial%20dysfunction%20by%20complementation%20of%20DNA%20products%20in%20fused%20mitochondria&journal=Nat%20Genet&doi=10.1038%2F90116&volume=28&pages=272-275&publication_year=2001&author=Ono%2CT&author=Isobe%2CK&author=Nakada%2CK&author=Hayashi%2CJI?
- https://doi.org/10.1016%2FS0968-0004%2800%2901735-7's total income per month
- http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20filaments%20and%20clusters%20as%20intracellular%20power-transmitting%20cables&journal=Trends%20Biochem%20Sci&doi=10.1016%2FS0968-0004%2800%2901735-7&volume=26&pages=23-29&publication_year=2001&author=Skulachev%2CVP's financial summary
- https://doi.org/10.1016%2Fj.cell.2006.06.025's revenue stream
- How much money does http://scholar.google.com/scholar_lookup?&title=OPA1%20controls%20apoptotic%20cristae%20remodeling%20independently%20from%20mitochondrial%20fusion&journal=Cell&doi=10.1016%2Fj.cell.2006.06.025&volume=126&pages=177-189&publication_year=2006&author=Frezza%2CC&author=Cipolat%2CS&author=Martins%20de%20Brito%2CO&author=Micaroni%2CM&author=Beznoussenko%2CGV&author=Rudka%2CT generate?
- Earnings of https://doi.org/10.1074%2Fjbc.C200677200
- Earnings of http://scholar.google.com/scholar_lookup?&title=Loss%20of%20OPA1%20perturbates%20the%20mitochondrial%20inner%20membrane%20structure%20and%20integrity%2C%20leading%20to%20cytochrome%20c%20release%20and%20apoptosis&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.C200677200&volume=278&pages=7743-7746&publication_year=2003&author=Olichon%2CA&author=Baricault%2CL&author=Gas%2CN&author=Guillou%2CE&author=Valette%2CA&author=Belenguer%2CP
- Learn how profitable https://doi.org/10.1083%2Fjcb.200209124 is on a monthly basis
- How much money does http://scholar.google.com/scholar_lookup?&title=Spatial%20and%20temporal%20association%20of%20Bax%20with%20mitochondrial%20fission%20sites%2C%20Drp1%2C%20and%20Mfn2%20during%20apoptosis&journal=J%20Cell%20Biol&doi=10.1083%2Fjcb.200209124&volume=159&pages=931-938&publication_year=2002&author=Karbowski%2CM&author=Lee%2CYJ&author=Gaume%2CB&author=Jeong%2CSY&author=Frank%2CS&author=Nechushtan%2CA make?
- How much revenue does https://doi.org/10.1074%2Fjbc.M501599200 bring in?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Activated%20mitofusin%202%20signals%20mitochondrial%20fusion%2C%20interferes%20with%20Bax%20activation%2C%20and%20reduces%20susceptibility%20to%20radical%20induced%20depolarization&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M501599200&volume=280&pages=25060-25070&publication_year=2005&author=Neuspiel%2CM&author=Zunino%2CR&author=Gangaraju%2CS&author=Rippstein%2CP&author=McBride%2CH?
- What are the total earnings of https://doi.org/10.1074%2Fjbc.M312366200?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Ca2%2B%20homeostasis%20during%20mitochondrial%20fragmentation%20and%20perinuclear%20clustering%20induced%20by%20hFis1&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M312366200&volume=279&pages=22704-22714&publication_year=2004&author=Frieden%2CM&author=James%2CD&author=Castelbou%2CC&author=Danckaert%2CA&author=Martinou%2CJC&author=Demaurex%2CN is on a monthly basis
- How much profit does https://doi.org/10.1038%2F35048069 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Breaking%20the%20mitochondrial%20barrier&journal=Nat%20Rev%20Mol%20Cell%20Biol&doi=10.1038%2F35048069&volume=2&pages=63-67&publication_year=2001&author=Martinou%2CJC&author=Green%2CDR bring in?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12543814's revenue stream
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Bcl-2%20and%20Bax%20modulate%20adenine%20nucleotide%20translocase%20activity&journal=Cancer%20Res&volume=63&pages=541-546&publication_year=2003&author=Belzacq%2CAS&author=Vieira%2CHL&author=Verrier%2CF&author=Vandecasteele%2CG&author=Cohen%2CI&author=Prevost%2CMC?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9425147 is on a monthly basis
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Energy%20deprivation%20and%20a%20deficiency%20in%20downstream%20metabolic%20target%20genes%20during%20the%20onset%20of%20embryonic%20heart%20failure%20in%20RXRalpha%E2%88%92%2F%E2%88%92%20embryos&journal=Development&volume=125&pages=533-544&publication_year=1998&author=Ruiz-Lozano%2CP&author=Smith%2CSM&author=Perkins%2CG&author=Kubalak%2CSW&author=Boss%2CGR&author=Sucov%2CHM
- What's the income of https://doi.org/10.1152%2Fjapplphysiol.00750.2004?
- How much does http://scholar.google.com/scholar_lookup?&title=Greater%20capillary-fiber%20interface%20per%20fiber%20mitochondrial%20volume%20in%20skeletal%20muscles%20of%20old%20rats&journal=J%20Appl%20Physiol&doi=10.1152%2Fjapplphysiol.00750.2004&volume=99&pages=281-289&publication_year=2005&author=Mathieu-Costello%2CO&author=Ju%2CY&author=Trejo-Morales%2CM&author=Cui%2CL earn?
- How much does https://doi.org/10.1054%2Fceca.2001.0238 make?
- How much income is http://scholar.google.com/scholar_lookup?&title=Selective%2C%20high-resolution%20fluorescence%20imaging%20of%20mitochondrial%20Ca2%2B%20concentration&journal=Cell%20Calcium&doi=10.1054%2Fceca.2001.0238&volume=30&pages=311-321&publication_year=2001&author=Gerencser%2CAA&author=Adam-Vizi%2CV earning monthly?
- Financial intake of https://citation-needed.springer.com/v2/references/10.1038/sj.cdd.4402046?format=refman&flavour=references
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=H%20Yuan generate monthly?
- How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22H%20Yuan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=A%20A%20Gerencser bring in?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22A%20A%20Gerencser%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
- What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=G%20Liot?
- Check the income stats for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22G%20Liot%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=S%20A%20Lipton bring in?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22S%20A%20Lipton%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
- How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%20Ellisman?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%20Ellisman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
- What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=G%20A%20Perkins?
- What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22G%20A%20Perkins%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=E%20Bossy-Wetzel pull in?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22E%20Bossy-Wetzel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
- How much does https://s100.copyright.com/AppDispatchServlet?title=Mitochondrial%20fission%20is%20an%20upstream%20and%20required%20event%20for%20bax%20foci%20formation%20in%20response%20to%20nitric%20oxide%20in%20cortical%20neurons&author=H%20Yuan%20et%20al&contentID=10.1038%2Fsj.cdd.4402046©right=Springer%20Nature%20Limited&publication=1350-9047&publicationDate=2006-10-20&publisherName=SpringerNature&orderBeanReset=true make?
- See how much https://citation-needed.springer.com/v2/references/10.1038/sj.cdd.4402046?format=refman&flavour=citation makes per month
- How profitable is https://doi.org/10.1186/s13578-023-01068-6?
- What's the financial gain of https://doi.org/10.1007/s11064-022-03804-9?
- How much income does https://doi.org/10.1007/s00424-019-02258-3 have?
- How much money does https://doi.org/10.1007/s12640-020-00213-0 make?
- How much profit is https://doi.org/10.1186/s13046-018-1008-8 making per month?
- How much profit does https://www.protocols.io/ make?
- Get to know https://www.natureindex.com/'s earnings
- http://www.naturechina.com's financial summary
- How much profit does https://www.natureasia.com/ja-jp make?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Angular
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref