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Title:
Serine proteases and calpains fulfill important supporting roles in the apoptotic tragedy of the cellular opera | Cell Death & Differentiation
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Cell Death & Differentiation - Serine proteases and calpains fulfill important supporting roles in the apoptotic tragedy of the cellular opera
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Keywords {π}
cell, death, htraomi, cleavage, protease, apoptosis, cells, granzyme, serine, proteases, caspases, mitochondrial, activation, caspase, activity, biol, calpain, nature, calpains, proteins, chem, role, protein, shown, function, proteolytic, dna, apoptotic, family, bcl, pai, differ, granzymes, unclear, thrombin, cleaved, cellular, nuclear, recently, par, bid, release, mitochondria, domain, calpastatin, data, important, complex, htra, process,
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n-acetyl-dl-phenylalanine-Ξ²-naphtyl ester nature portfolio molecular biomedical research n-tosyl-l-phenylalanine chloromethyl ketone n-tosyl-l-arginine methyl ester permissions reprints n-tosyl-l-lysine chloromethyl ketone privacy policy advertising nature 377 nature 425 nature social media couple ap24/l-dnase ii development author correspondence single-stranded dna nicking htra2/omi-induced cell death endonuclease l-dnase ii calcium/calmodulin-dependent kinase peptide bond c-terminal myocardial ischemia-reperfusion damage single-stranded dna damage c-terminal pdz domains access htra2/omi strongly impairs ap24/l-dnase ii er-mitochondrial organelle system ap24-mediated dna fragmentation accumulating data suggest permissions apollon ubiquitinates htra2/omi granzyme b-mediated processing uv light-induced apoptosis serine protease htra2/omi omi/htra2 serine protease granzyme a-mediated cleavage necrotic cell death caspase-dependent cell death m-calpains require micromolar l-dnase ii released m-calpain decreases htra2/omi proteolytic activity inhibit tnf-mediated cytotoxicity inhibits calpain-dependent degradation c-terminal regions n-terminal mls n-terminal ibms mammalian htra2/omi functions focal adhesion kinase
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