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Primary structure and expression of a functional human glucocorticoid receptor cDNA | Nature
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Identification of complementary DNAs encoding the human glucocorticoid receptor predicts two protein forms, of 777 (α) and 742 (β) amino acids, which differ at their carboxy termini. The proteins contain a cysteine/lysine/arginine-rich region which may define the DNA-binding domain. Pure radiolabelled glucocorticoid receptor, synthesized in vitro, is immuno-reactive and possesses intrinsic steroid-binding activity characteristic of the native glucocorticoid receptor.
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