NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Non-Profit & Charity

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$531,700 per month
Our estimates place Nature.com's monthly online earnings from display ads at $354,480 to $974,820.

Keywords {🔍}

article, scholar, google, cas, human, nature, cells, cancer, telomerase, ads, cell, access, usa, research, content, cookies, hahn, counter, weinberg, activity, privacy, william, lundberg, transformation, normal, expression, epithelial, fibroblasts, proc, natl, acad, sci, mol, biol, data, tumour, christopher, ante, robert, primary, tumorigenic, oncogenes, simian, virus, ras, tumor, senescence, oncogene, science, large,

Topics {✒️}

nature portfolio permissions reprints privacy policy advertising social media mouse development biomedical research nature genet subscribe nature middle nature 304 nature 394 nature 396 nature 400 nature human tfiib-related factor dana-farber cancer institute personal data author correspondence springerlink instant access data protection permissions normal human epithelial defined genetic elements entire viral genome11 privacy human fibroblasts caused human fibroblasts immortalized normal human cells harvard medical school human tumor cell transform primary cells cellular transforming genes prostate epithelial cells human epidermal keratinocytes normal epithelium outcompete human somatic cells explore content subscription content human tumour cells european economic area intracellular pathways regulated institutional subscriptions read activated v-myc kirsten sarcoma viruses cold spring harb rb/p16ink4a inactivation polymerase iii promoter nucleic acids res histone deacetylase inhibitors

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Creation of human tumour cells with defined genetic elements
         description:During malignant transformation, cancer cells acquire genetic mutations that override the normal mechanisms controlling cellular proliferation. Primary rodent cells are efficiently converted into tumorigenic cells by the coexpression of cooperating oncogenes1,2. However, similar experiments with human cells have consistently failed to yield tumorigenic transformants3,4,5, indicating a fundamental difference in the biology of human and rodent cells. The few reported successes in the creation of human tumour cells have depended on the use of chemical or physical agents to achieve immortalization6, the selection of rare, spontaneously arising immortalized cells7,8,9,10, or the use of an entire viral genome11. We show here that the ectopic expression of the telomerase catalytic subunit (hTERT)12 in combination with two oncogenes (the simian virus 40 large-T oncoprotein and an oncogenic allele of H-ras) results in direct tumorigenic conversion of normal human epithelial and fibroblast cells. These results demonstrate that disruption of the intracellular pathways regulated by large-T, oncogenic ras and telomerase suffices to create a human tumor cell.
         datePublished:
         dateModified:
         pageStart:464
         pageEnd:468
         sameAs:https://doi.org/10.1038/22780
         keywords:
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig4_HTML.gif
         isPartOf:
            name:Nature
            issn:
               1476-4687
               0028-0836
            volumeNumber:400
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:William C. Hahn
               affiliation:
                     name:Whitehead Institute for Biomedical Research
                     address:
                        name:Whitehead Institute for Biomedical Research
                        type:PostalAddress
                     type:Organization
                     name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
                     address:
                        name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Christopher M. Counter
               affiliation:
                     name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
                     address:
                        name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
                        type:PostalAddress
                     type:Organization
                     name:Duke University Medical Center
                     address:
                        name:Duke University Medical Center, Durham, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ante S. Lundberg
               affiliation:
                     name:Whitehead Institute for Biomedical Research
                     address:
                        name:Whitehead Institute for Biomedical Research
                        type:PostalAddress
                     type:Organization
                     name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
                     address:
                        name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Roderick L. Beijersbergen
               affiliation:
                     name:Whitehead Institute for Biomedical Research
                     address:
                        name:Whitehead Institute for Biomedical Research
                        type:PostalAddress
                     type:Organization
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mary W. Brooks
               affiliation:
                     name:Whitehead Institute for Biomedical Research
                     address:
                        name:Whitehead Institute for Biomedical Research
                        type:PostalAddress
                     type:Organization
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Robert A. Weinberg
               affiliation:
                     name:Whitehead Institute for Biomedical Research
                     address:
                        name:Whitehead Institute for Biomedical Research
                        type:PostalAddress
                     type:Organization
                     name:Massachusetts Institute of Technology
                     address:
                        name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Creation of human tumour cells with defined genetic elements
      description:During malignant transformation, cancer cells acquire genetic mutations that override the normal mechanisms controlling cellular proliferation. Primary rodent cells are efficiently converted into tumorigenic cells by the coexpression of cooperating oncogenes1,2. However, similar experiments with human cells have consistently failed to yield tumorigenic transformants3,4,5, indicating a fundamental difference in the biology of human and rodent cells. The few reported successes in the creation of human tumour cells have depended on the use of chemical or physical agents to achieve immortalization6, the selection of rare, spontaneously arising immortalized cells7,8,9,10, or the use of an entire viral genome11. We show here that the ectopic expression of the telomerase catalytic subunit (hTERT)12 in combination with two oncogenes (the simian virus 40 large-T oncoprotein and an oncogenic allele of H-ras) results in direct tumorigenic conversion of normal human epithelial and fibroblast cells. These results demonstrate that disruption of the intracellular pathways regulated by large-T, oncogenic ras and telomerase suffices to create a human tumor cell.
      datePublished:
      dateModified:
      pageStart:464
      pageEnd:468
      sameAs:https://doi.org/10.1038/22780
      keywords:
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2F22780/MediaObjects/41586_1999_Article_BF22780_Fig4_HTML.gif
      isPartOf:
         name:Nature
         issn:
            1476-4687
            0028-0836
         volumeNumber:400
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:William C. Hahn
            affiliation:
                  name:Whitehead Institute for Biomedical Research
                  address:
                     name:Whitehead Institute for Biomedical Research
                     type:PostalAddress
                  type:Organization
                  name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
                  address:
                     name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Christopher M. Counter
            affiliation:
                  name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
                  address:
                     name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
                     type:PostalAddress
                  type:Organization
                  name:Duke University Medical Center
                  address:
                     name:Duke University Medical Center, Durham, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ante S. Lundberg
            affiliation:
                  name:Whitehead Institute for Biomedical Research
                  address:
                     name:Whitehead Institute for Biomedical Research
                     type:PostalAddress
                  type:Organization
                  name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
                  address:
                     name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Roderick L. Beijersbergen
            affiliation:
                  name:Whitehead Institute for Biomedical Research
                  address:
                     name:Whitehead Institute for Biomedical Research
                     type:PostalAddress
                  type:Organization
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mary W. Brooks
            affiliation:
                  name:Whitehead Institute for Biomedical Research
                  address:
                     name:Whitehead Institute for Biomedical Research
                     type:PostalAddress
                  type:Organization
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Robert A. Weinberg
            affiliation:
                  name:Whitehead Institute for Biomedical Research
                  address:
                     name:Whitehead Institute for Biomedical Research
                     type:PostalAddress
                  type:Organization
                  name:Massachusetts Institute of Technology
                  address:
                     name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature
      issn:
         1476-4687
         0028-0836
      volumeNumber:400
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Whitehead Institute for Biomedical Research
      address:
         name:Whitehead Institute for Biomedical Research
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
      address:
         name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
      address:
         name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
         type:PostalAddress
      name:Duke University Medical Center
      address:
         name:Duke University Medical Center, Durham, USA
         type:PostalAddress
      name:Whitehead Institute for Biomedical Research
      address:
         name:Whitehead Institute for Biomedical Research
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
      address:
         name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Whitehead Institute for Biomedical Research
      address:
         name:Whitehead Institute for Biomedical Research
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Whitehead Institute for Biomedical Research
      address:
         name:Whitehead Institute for Biomedical Research
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
      name:Whitehead Institute for Biomedical Research
      address:
         name:Whitehead Institute for Biomedical Research
         type:PostalAddress
      name:Massachusetts Institute of Technology
      address:
         name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:William C. Hahn
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research
               type:PostalAddress
            type:Organization
            name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
            address:
               name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Massachusetts Institute of Technology
            address:
               name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Christopher M. Counter
      affiliation:
            name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
            address:
               name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
               type:PostalAddress
            type:Organization
            name:Duke University Medical Center
            address:
               name:Duke University Medical Center, Durham, USA
               type:PostalAddress
            type:Organization
      name:Ante S. Lundberg
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research
               type:PostalAddress
            type:Organization
            name:Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
            address:
               name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Massachusetts Institute of Technology
            address:
               name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Roderick L. Beijersbergen
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research
               type:PostalAddress
            type:Organization
            name:Massachusetts Institute of Technology
            address:
               name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Mary W. Brooks
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research
               type:PostalAddress
            type:Organization
            name:Massachusetts Institute of Technology
            address:
               name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Robert A. Weinberg
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research
               type:PostalAddress
            type:Organization
            name:Massachusetts Institute of Technology
            address:
               name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Whitehead Institute for Biomedical Research
      name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
      name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
      name:Department of Pharmacology and Cancer Biology, Department of Radiation Oncology
      name:Duke University Medical Center, Durham, USA
      name:Whitehead Institute for Biomedical Research
      name:Department of Adult Oncology, Departments of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
      name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
      name:Whitehead Institute for Biomedical Research
      name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
      name:Whitehead Institute for Biomedical Research
      name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
      name:Whitehead Institute for Biomedical Research
      name:Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/Nature
• https://twitter.com/nature

External Links {🔗}(99)

• https://link.springer.com/article/10.1038/22780?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle's total income per month
• How much income is https://doi.org/10.1038%2F304596a0 earning monthly?
• What is the earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1983Natur.304..596L?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Tumorigenic%20conversion%20of%20primary%20embryo%20fibroblasts%20requires%20at%20least%20two%20cooperating%20oncogenes.&journal=Nature&doi=10.1038%2F304596a0&volume=304&pages=596-602&publication_year=1983&author=Land%2CH&author=Parada%2CLF&author=Weinberg%2CRA is on a monthly basis
• What is the earnings of https://doi.org/10.1038%2F304602a0?
• How profitable is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1983Natur.304..602R?
• How much money does http://scholar.google.com/scholar_lookup?&title=Adenovirus%20early%20region%201A%20enables%20viral%20and%20cellular%20transforming%20genes%20to%20transform%20primary%20cells%20in%20culture.&journal=Nature&doi=10.1038%2F304602a0&volume=304&pages=602-606&publication_year=1983&author=Ruley%2CH generate?
• Check the income stats for https://doi.org/10.1289%2Fehp.919359
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Senescence%20as%20a%20mode%20of%20tumor%20suppression.&journal=Environ.%20Health%20Perspect.&doi=10.1289%2Fehp.919359&volume=93&pages=59-62&publication_year=1991&author=Sager%2CR
• What are the total earnings of https://doi.org/10.1073%2Fpnas.83.22.8659?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1986PNAS...83.8659O produce monthly?
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Suppression%20of%20tumor%20growth%20by%20senescence%20in%20virally%20transformed%20human%20fibroblasts.&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.83.22.8659&volume=83&pages=8659-8663&publication_year=1986&author=O%27Brien%2CW&author=Stenman%2CG&author=Sager%2CR?
• What's the financial intake of https://doi.org/10.1128%2FMCB.6.10.3410?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Activated%20v-myc%20and%20v-ras%20oncogenes%20do%20not%20transform%20normal%20human%20lymphocytes.&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.6.10.3410&volume=6&pages=3410-3417&publication_year=1986&author=Stevenson%2CM&author=Volsky%2CDJ generate?
• What's the monthly money flow for https://doi.org/10.1002%2F%28SICI%291098-2744%28199804%2921%3A4%3C225%3A%3AAID-MC1%3E3.0.CO%3B2-J?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20tyrosine%20phosphorylation%20of%20p185c-erb%2Fneu%20in%20tumorigenicity%20induced%20by%20X-rays%20and%20the%20neu%20oncogene%20in%20human%20breast%20epithelial%20cells.&journal=Mol.%20Carcinogen.&doi=10.1002%2F%28SICI%291098-2744%28199804%2921%3A4%3C225%3A%3AAID-MC1%3E3.0.CO%3B2-J&volume=21&pages=225-233&publication_year=1998&author=Kang%2CJ-S
• Check the income stats for https://doi.org/10.1126%2Fscience.3975607
• What's the income of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1985Sci...227.1174Y?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Transformation%20of%20human%20bronchial%20epithelial%20cells%20transfected%20by%20the%20Harvey%20ras%20oncogene.&journal=Science&doi=10.1126%2Fscience.3975607&volume=227&pages=1174-1179&publication_year=1985&author=Yakum%2CGH
• How much does https://doi.org/10.1126%2Fscience.2579430 make?
• How much income is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1985Sci...227.1250R earning monthly?
• Get to know http://scholar.google.com/scholar_lookup?&title=Neoplastic%20transformation%20of%20human%20epidermal%20keratinocytes%20by%20AD12-SV40%20and%20Kirsten%20sarcoma%20viruses.&journal=Science&doi=10.1126%2Fscience.2579430&volume=227&pages=1250-1252&publication_year=1985&author=Rhim%2CJS's earnings
• What are the earnings of https://doi.org/10.1073%2Fpnas.86.1.187?
• What's the income generated by http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1989PNAS...86..187H each month?
• Get to know http://scholar.google.com/scholar_lookup?&title=Malignant%20transformation%20of%20human%20fibroblasts%20caused%20by%20expression%20of%20a%20transfected%20T24%20HRAS%20oncogene.&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.86.1.187&volume=86&pages=187-181&publication_year=1989&author=Hurlin%2CPJ&author=Maher%2CVM&author=McCormick%2CJJ's earnings
• What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9772298?
• See how much http://scholar.google.com/scholar_lookup?&title=Effect%20of%20oncogene%20expression%20on%20telomerase%20activation%20and%20telomere%20length%20in%20human%20endothelial%2C%20fibroblast%20and%20prostate%20epithelial%20cells.&journal=Int.%20J.%20Oncol.&volume=13&pages=1043-1048&publication_year=1998&author=Burger%2CAM makes per month
• How much profit does https://doi.org/10.1038%2F29093 generate?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998Natur.394..588F generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Transformation%20of%20primary%20human%20endothelial%20cells%20by%20Kaposi%27s%20sarcoma-associated%20herpesvirus.&journal=Nature&doi=10.1038%2F29093&volume=394&pages=588-592&publication_year=1998&author=Flore%2CA bring in each month?
• How much cash flow does https://doi.org/10.1016%2FS0092-8674%2800%2981123-X have monthly?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Reversing%20time%3A%20origin%20of%20telomerase.&journal=Cell&doi=10.1016%2FS0092-8674%2800%2981123-X&volume=92&pages=587-590&publication_year=1998&author=Nakamura%2CTM&author=Cech%2CTR?
• How much does https://doi.org/10.1016%2FS0959-8049%2897%2900060-9 pull in monthly?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Telomere%20structure%20and%20telomerase%20expression%20during%20mouse%20development%20and%20tumorigenesis.&journal=Eur.%20J.%20Cancer&doi=10.1016%2FS0959-8049%2897%2900060-9&volume=33&pages=792-800&publication_year=1997&author=Kipling%2CD?
• Find out how much https://doi.org/10.1126%2Fscience.7605428 earns monthly
• What are the earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1994Sci...266.2011K?
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Specific%20association%20of%20human%20telomerase%20activity%20with%20immortal%20cells%20and%20cancer.&journal=Science&doi=10.1126%2Fscience.7605428&volume=266&pages=2011-2015&publication_year=1994&author=Kim%2CNW?
• How much does https://doi.org/10.1016%2FS0959-8049%2897%2900062-2 generate monthly?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Asurvey%20of%20telomerase%20activity%20in%20human%20cancer.&journal=Eur.%20J.%20Cancer&doi=10.1016%2FS0959-8049%2897%2900062-2&volume=33&pages=787-791&publication_year=1997&author=Shay%2CJW&author=Bacchetti%2CS making per month?
• Monthly income for https://doi.org/10.1101%2FSQB.1994.059.01.035
• How much does http://scholar.google.com/scholar_lookup?&title=Telomerase%2C%20cell%20immortality%2C%20and%20cancer.&journal=Cold%20Spring%20Harb.%20Symp.%20Quant.%20Biol.&doi=10.1101%2FSQB.1994.059.01.035&volume=59&pages=307-315&publication_year=1994&author=Harley%2CCB generate monthly?
• Profit of https://doi.org/10.1126%2Fscience.279.5349.349
• What's the revenue for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998Sci...279..349B?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Extension%20of%20life-span%20by%20introduction%20of%20telomerase%20into%20normal%20human%20cells.&journal=Science&doi=10.1126%2Fscience.279.5349.349&volume=279&pages=349-352&publication_year=1998&author=Bodnar%2CAG
• How much cash flow does https://doi.org/10.1038%2F23962 have monthly?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998Natur.396...84K bring in?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Both%20Rb%2Fp16INK4a%20inactivation%20and%20telomerase%20activity%20are%20required%20to%20immortalize%20human%20epithelial%20cells.&journal=Nature&doi=10.1038%2F23962&volume=396&pages=84-88&publication_year=1998&author=Kiyono%2CT?
• https://doi.org/10.1073%2Fpnas.96.7.3339 income
• What are the total earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1999PNAS...96.3339L?
• http://scholar.google.com/scholar_lookup?&title=Crisis%20intervention%3A%20the%20role%20of%20telomerase.&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.96.7.3339&volume=96&pages=3339-3341&publication_year=1999&author=Lustig%2CAJ's revenue stream
• What are the earnings of https://doi.org/10.1016%2FS0092-8674%2800%2981902-9?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Oncogenic%20ras%20provokes%20premature%20cell%20senescence%20associated%20with%20accumulation%20of%20p53%20nd%20p16ink4a.&journal=Cell&doi=10.1016%2FS0092-8674%2800%2981902-9&volume=88&pages=593-602&publication_year=1997&author=Serrano%2CM&author=Lin%2CAW&author=McCurrach%2CME&author=Beach%2CD&author=Lowe%2CSW
• How much does https://doi.org/10.1073%2Fpnas.95.25.14723 make?
• What's the revenue for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998PNAS...9514723C?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Dissociation%20among%20in%20vitro%20telomerase%20activity%2C%20telomere%20maintenance%2C%20and%20cellular%20immortalization.&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.95.25.14723&volume=95&pages=14723-14728&publication_year=1998&author=Counter%2CCM
• What's the financial intake of https://doi.org/10.1038%2F5063?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1999Natur.399..115M generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Absence%20of%20cancer-associated%20changes%20in%20human%20fibroblasts%20immortalized%20with%20telomerase.&journal=Nature%20Genet.&doi=10.1038%2F5063&volume=21&pages=115-118&publication_year=1999&author=Morales%2CCP produce monthly?
• Get to know https://doi.org/10.1128%2FMCB.18.3.1408's earnings
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=The%20J%20domain%20of%20simian%20virus%2040%20large%20T%20antigen%20is%20required%20to%20functionally%20inactivate%20RB%20family%20proteins.&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.18.3.1408&volume=18&pages=1408-1415&publication_year=1998&author=Zalvide%2CJ&author=Stubdal%2CH&author=DeCaprio%2CJA?
• https://doi.org/10.1128%2FMCB.18.3.1331's financial summary
• http://scholar.google.com/scholar_lookup?&title=Simian%20virus%2040%20large%20T%20antigen%20interacts%20with%20human%20TFIIB-related%20factor%20and%20small%20nuclear%20RNA-activating%20protein%20complex%20for%20transcriptional%20activation%20of%20TATA-containing%20polymerase%20III%20promoter.&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.18.3.1331&volume=18&pages=1331-1338&publication_year=1998&author=Damania%2CB&author=Mital%2CR&author=Alwine%2CJC's revenue stream
• How much money does http://scholar.google.com/scholar_lookup?&title=Immortalized%20cells%20with%20no%20detectable%20telomerase%20activity.%20A%20review.&journal=Biochemistry%20%28Mosc.%29&volume=62&pages=1254-1262&publication_year=1997&author=Reddel%2CRR&author=Bryan%2CTM&author=Murnane%2CJP make?
• How much does https://doi.org/10.1038%2F5056 rake in every month?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Telomerase%20expression%20in%20human%20somatic%20cells%20does%20not%20induce%20changes%20associated%20with%20a%20transformed%20phenotype.&journal=Nature%20Genet.&doi=10.1038%2F5056&volume=21&pages=111-114&publication_year=1999&author=Jiang%2CX-R?
• https://doi.org/10.1128%2FMCB.6.4.1204 income
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Recombinant%20retroviruses%20encoding%20simian%20virus%2040%20large%20T%20antigen%20and%20polyomavirus%20large%20and%20middle%20T%20antigens.&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.6.4.1204&volume=6&pages=1204-1217&publication_year=1986&author=Jat%2CPS&author=Cepko%2CCL&author=Mulligan%2CRC&author=Sharp%2CPA is on a monthly basis
• Find out how much https://doi.org/10.1093%2Fnar%2F25.13.2595 earns monthly
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Advances%20in%20quantification%20and%20characterization%20of%20telomerase%20activity%20by%20the%20telomeric%20repeat%20amplification%20protocol%20%28TRAP%29.&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F25.13.2595&volume=25&pages=2595-2597&publication_year=1997&author=Kim%2CNW&author=Wu%2CF
• How much does https://doi.org/10.1073%2Fpnas.77.2.1039 make?
• How much income does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1980PNAS...77.1039C have?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Correlation%20of%20patterns%20of%20anchorage-independent%20growth%20with%20in%20vivo%20behavior%20of%20cells%20from%20a%20murine%20fibrosarcoma.&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.77.2.1039&volume=77&pages=1039-1043&publication_year=1980&author=Cifone%2CMA&author=Fidler%2CIJ have monthly?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7815516 gross monthly?
• What's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC188715?
• How much does http://scholar.google.com/scholar_lookup?&title=Potential%20role%20of%20natural%20killer%20cells%20in%20controlling%20tumorigenesis%20by%20human%20T-cell%20leukemia%20viruses.&journal=J.%20Virol.&volume=69&pages=1328-1333&publication_year=1995&author=Feuer%2CG gross monthly?
• What's the income of https://citation-needed.springer.com/v2/references/10.1038/22780?format=refman&flavour=references?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=William%20C.%20Hahn's financial summary
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22William%20C.%20Hahn%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Christopher%20M.%20Counter?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Christopher%20M.%20Counter%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ante%20S.%20Lundberg?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ante%20S.%20Lundberg%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Roderick%20L.%20Beijersbergen
• How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Roderick%20L.%20Beijersbergen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mary%20W.%20Brooks?
• Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mary%20W.%20Brooks%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Robert%20A.%20Weinberg making per month?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Robert%20A.%20Weinberg%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• How much profit does https://s100.copyright.com/AppDispatchServlet?title=Creation%20of%20human%20tumour%20cells%20with%20defined%20genetic%20elements&author=William%20C.%20Hahn%20et%20al&contentID=10.1038%2F22780©right=Macmillan%20Magazines%20Ltd.&publication=0028-0836&publicationDate=1999-07-29&publisherName=SpringerNature&orderBeanReset=true make?
• Profit of https://citation-needed.springer.com/v2/references/10.1038/22780?format=refman&flavour=citation
• How much does https://doi.org/10.1186/s12935-023-03041-2 pull in?
• What's https://doi.org/10.1007/s13577-023-00925-3's gross income?
• Get to know https://doi.org/10.1186/s13058-022-01538-8's earnings
• How much profit does https://doi.org/10.1186/s12859-022-04788-7 make?
• Financial intake of https://doi.org/10.1186/s13148-022-01370-z
• Learn about the earnings of https://www.protocols.io/
• How much does https://www.natureindex.com/ pull in monthly?
• How much revenue does http://www.naturechina.com generate?
• Revenue of https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref