
BIOCONDUCTOR . ORG {
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Title:
Bioconductor - vsn
Description:
The package implements a method for normalising microarray intensities from single- and multiple-color arrays. It can also be used for data from other technologies, as long as they have similar format. The method uses a robust variant of the maximum-likelihood estimator for an additive-multiplicative error model and affine calibration. The model incorporates data calibration step (a.k.a. normalization), a model for the dependence of the variance on the mean intensity and a variance stabilizing data transformation. Differences between transformed intensities are analogous to
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Keywords {🔍}
bioconductor, package, version, packages, vsn, data, variance, release, source, calibration, microarray, model, install, pdf, binary, learn, developers, started, software, method, intensities, wolfgang, huber, installation, start, enter, documentation, system, html, script, details, bioc, url, macos, vsntgz, repository, git, clone, reports, code, registration, open, gbcc, joint, galaxybioconductor, conference, search, menu, home, released,
Topics {✒️}
org/packages/vsn source repository joint galaxy/bioconductor conference additive-multiplicative error model bioconductor release tgz source repository source package release //code bioconductor support site multiple-color arrays maximum-likelihood estimator normalized log-ratios detecting differential transcription anja von heydebreck hans-ulrich klein gz windows binary zip macos binary tgz macos binary script likelihood calculations package implements package installed git clone https pdf reference manual details biocviews ggplot2 system requirements normalising microarray intensities r-project packages package started install org http simulated data bioconductor //bioconductor affine calibration wolfgang huber transformed intensities script verifying registration open variance stabilization similar format robust variant dennis kostka david kreil robert gentleman deepayan sarkar quietly = true older versions pdf news biobase imports
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