
BIOCONDUCTOR . ORG {
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Title:
Bioconductor - timescape
Description:
TimeScape is an automated tool for navigating temporal clonal evolution data. The key attributes of this implementation involve the enumeration of clones, their evolutionary relationships and their shifting dynamics over time. TimeScape requires two inputs: (i) the clonal phylogeny and (ii) the clonal prevalences. Optionally, TimeScape accepts a data table of targeted mutations observed in each clone and their allele prevalences over time. The output is the TimeScape plot showing clonal prevalence vertically, time horizontally, and the plot height optionally encoding tumour volume during tumour-shrinking events. At each sampling time point (denoted by a faint white line), the height of each clone accurately reflects its proportionate prevalence. These prevalences form the anchors for bezier curves that visually represent the dynamic transitions between time points.
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Keywords {🔍}
bioconductor, package, timescape, version, packages, clonal, time, release, clone, source, prevalences, smith, enter, install, binary, learn, developers, started, software, patient, timescapes, data, optionally, plot, prevalence, height, maia, httpsbioconductororgpackagestimescape, installation, start, documentation, system, details, bioc, url, macos, timescapetgz, repository, git, reports, code, registration, open, gbcc, joint, galaxybioconductor, conference, search, menu, home,
Topics {✒️}
org/packages/timescape source repository joint galaxy/bioconductor conference bioconductor release tgz source repository source package org/packages/timescape patient clonal timescapes tumour-shrinking events release //code bioconductor support site targeted mutations observed faint white line script reference manual clone accurately reflects gz windows binary package installed maia smith [aut package version 1 tgz macos binary details biocviews sampling time point git clone https package started install packages proportionate prevalence clonal phylogeny clonal prevalences data table macos binary timescape requires timescape accepts timescape vignette //bioconductor bioconductor registration open automated tool key attributes implementation involve evolutionary relationships shifting dynamics allele prevalences prevalences form bezier curves visually represent dynamic transitions cre] maintainer quietly = true older versions
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