BIOCONDUCTOR . ORG {
}
Title:
Bioconductor - synergyfinder
Description:
Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (http://www.synergyfinder.org) for users who prefer graphical user interface.
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Keywords {🔍}
bioconductor, package, synergy, drug, packages, synergyfinder, version, combination, release, source, provide, zheng, enter, install, binary, learn, developers, started, software, combinations, efficient, implementations, multiple, datasets, scoring, analysis, sensitivity, methods, interpretation, httpwwwsynergyfinderorg, user, shuyu, aut, tang, installation, start, documentation, system, details, bioc, license, stats, url, macos, synergyfindertgz, repository, git, clone, reports, code,
Topics {✒️}
org/packages/synergyfinder source repository joint galaxy/bioconductor conference bioconductor release tgz source repository source package drug combination synergy release //code bioconductor support site script reference manual gz windows binary tgz macos binary visualize synergy scores synergy landscape visualization shuyu zheng [aut package installed git clone https details biocviews zip macos binary clinical potential drug combinations packages started install package statistical analysis user tutorial synergy barometer bioconductor //bioconductor registration open efficient implementations including hsa unlimited number combination confidence intervals p-values consensus metric web application proteomics & bioinformatics quietly = true older versions pdf news developer access released version devel version statisticalmethod version sensitivity simultaneously unbiased interpretation view documentation system requirements
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