
BIOCONDUCTOR . ORG {
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Title:
Bioconductor - regutools
Description:
RegulonDB has collected, harmonized and centralized data from hundreds of experiments for nearly two decades and is considered a point of reference for transcriptional regulation in Escherichia coli K12. Here, we present the regutools R package to facilitate programmatic access to RegulonDB data in computational biology. regutools provides researchers with the possibility of writing reproducible workflows with automated queries to RegulonDB. The regutools package serves as a bridge between RegulonDB data and the Bioconductor ecosystem by reusing the data structures and statistical methods powered by other Bioconductor packages. We demonstrate the integration of regutools with Bioconductor by analyzing transcription factor DNA binding sites and transcriptional regulatory networks from RegulonDB. We anticipate that regutools will serve as a useful building block in our progress to further our understanding of gene regulatory networks.
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Keywords {๐}
package, bioconductor, regutools, regulondb, packages, version, data, orcid, aut, release, source, extraction, access, regulatory, networks, barberenajonas, sotelofonseca, alquicirahernandez, salgado, colladotorres, reyes, enter, install, reports, binary, learn, developers, started, software, reference, transcriptional, programmatic, workflows, methods, transcription, joselyn, chavez, ctb, chรกvez, httpsgithubcomcomunidadbioinforegutools, installation, start, documentation, system, details, bioc, stats, url, macos, regutoolstgz,
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org/packages/regutools source repository /comunidadbioinfo/regutools bug reports /bioinformatics/advance-article-abstract/doi/10 joint galaxy/bioconductor conference bioconductor release tgz source repository source package writing reproducible workflows org/packages/regutools release regutools package serves joselyn chavez [aut //code bioconductor packages sotelo-fonseca je escherichia coli k12 gene regulatory networks bacterial regulatory networks gz windows binary zip macos binary tgz macos binary bioconductor support site transcriptional regulatory networks statistical methods powered script reference manual details biocviews biocfilecache system requirements git clone https facilitate programmatic access package installed package version 1 started install cre] orcid bioconductor ecosystem barberena-jonas alquicira-hernandez collado-torres packages /comunidadbioinfo/regutools package ๏ฟฝprogrammatic access transcriptional regulation 1093/bioinformatics/btaa575 1093/bioinformatics/btaa575/5861528 developer access bioconductor //bioconductor registration open data extraction centralized data
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