BIOCONDUCTOR . ORG {
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Title:
Bioconductor - multtest
Description:
Non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.
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Keywords {🔍}
bioconductor, package, packages, multtest, version, release, source, multiple, testing, procedures, methods, rate, based, pollard, install, binary, learn, developers, started, software, resamplingbased, including, familywise, error, false, null, distribution, centered, tstatistics, parameters, survival, microarray, katherine, dudoit, enter, installation, details, bioc, stats, url, macos, multtesttgz, repository, git, clone, reports, code, registration, open, gbcc,
Topics {✒️}
org/packages/multtest source repository family-wise error rate joint galaxy/bioconductor conference bootstrap-based null distribution bioconductor release tgz source repository source package multiple testing procedures including t-statistics based release multtest package //code bioconductor support site false discovery rate step-wise methods vector influence function adjusted p-values test statistic cutoffs computational biology solutions stats4 system requirements gz windows binary zip macos binary tgz macos binary git clone https dna microarray experiments details biocviews package packages started install tests based parametric bootstrap t-statistics software version f-statistics bioconductor //bioconductor false positives single-step org registration open released version devel version tail probability quantile-transformed regression parameters correlation parameters probing hypotheses multivariate normal confidence regions directly applicable
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