BIOCONDUCTOR . ORG {
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Title:
Bioconductor - lemur
Description:
Fit a latent embedding multivariate regression (LEMUR) model to multi-condition single-cell data. The model provides a parametric description of single-cell data measured with treatment vs. control or more complex experimental designs. The parametric model is used to (1) align conditions, (2) predict log fold changes between conditions for all cells, and (3) identify cell neighborhoods with consistent log fold changes. For those neighborhoods, a pseudobulked differential expression test is conducted to assess which genes are significantly changed.
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Keywords {🔍}
bioconductor, package, packages, version, source, lemur, regression, release, singlecell, latent, embedding, multivariate, model, data, ahlmanneltze, enter, install, license, bioc, reports, binary, learn, developers, started, software, doi, multicondition, parametric, control, conditions, log, fold, neighborhoods, constantin, installation, start, documentation, system, text, details, stats, url, macos, lemurtgz, repository, git, clone, code, registration, open,
Topics {✒️}
/const-ae/lemur bug reports multi-condition single-cell data org/packages/lemur source repository single-cell data measured joint galaxy/bioconductor conference /const-ae/lemur/issues bioconductor release constantin ahlmann-eltze [aut tgz source repository source package source packages release control //code bioconductor support site identify cell neighborhoods complex experimental designs predict log fold consistent log fold script reference manual gz windows binary zip macos binary tgz macos binary package installed git clone https details biocviews biocneighbors system requirements source archive package ahlmann-eltze started install packages bioconductor //bioconductor org registration open parametric description significantly changed cre] orcid 0000-0002-3762-068x maintainer quietly = true older versions pdf news developer access text license released version devel version transcriptomics version align conditions view documentation
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