BIOCONDUCTOR . ORG {
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Title:
Bioconductor - epiregulon
Description:
Gene regulatory networks model the underlying gene regulation hierarchies that drive gene expression and observed phenotypes. Epiregulon infers TF activity in single cells by constructing a gene regulatory network (regulons). This is achieved through integration of scATAC-seq and scRNA-seq data and incorporation of public bulk TF ChIP-seq data. Links between regulatory elements and their target genes are established by computing correlations between chromatin accessibility and gene expressions.
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Keywords {🔍}
bioconductor, package, epiregulon, packages, version, gene, regulatory, release, aut, source, network, data, yao, enter, install, license, reports, binary, learn, developers, started, software, inference, single, doi, activity, xiaosai, orcid, lun, chen, singlecell, transcription, installation, start, documentation, system, text, details, bioc, stats, bsgenomehsapiensucschg, url, macos, epiregulontgz, repository, git, clone, code, registration, open,
Topics {✒️}
org/packages/epiregulon source repository /xiaosaiyao/epiregulon/ bug reports joint galaxy/bioconductor conference bioconductor release tgz source repository source package scrna-seq data release org/content/early/2023/11/28/2023 //code bioconductor support site /xiaosaiyao/epiregulon/issues drive gene expression gene regulatory network script reference manual gz windows binary zip macos binary tgz macos binary package installed xiaosai yao [aut aaron lun [aut] git clone https details biocviews beachmat system requirements package packages started install single cells scatac-seq gene expressions transcription version regulatory elements epiregulon tutorial cre] orcid bioconductor //bioconductor registration open observed phenotypes target genes computing correlations chromatin accessibility siebel cw corces mr dissect mechanisms lineage plasticity drug response quietly = true older versions pdf news singlecellexperiment imports
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