BIOCONDUCTOR . ORG {
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Title:
Bioconductor - dmrseq
Description:
This package implements an approach for scanning the genome to detect and perform accurate inference on differentially methylated regions from Whole Genome Bisulfite Sequencing data. The method is based on comparing detected regions to a pooled null distribution, that can be implemented even when as few as two samples per population are available. Region-level statistics are obtained by fitting a generalized least squares (GLS) regression model with a nested autoregressive correlated error structure for the effect of interest on transformed methylation proportions.
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Keywords {🔍}
bioconductor, package, packages, version, dmrseq, regions, genome, sequencing, release, aut, source, differentially, methylated, bisulfite, keegan, korthauer, enter, install, license, binary, learn, developers, started, software, detection, inference, accurate, data, regression, orcid, irizarry, benjamini, chakraborty, control, installation, start, documentation, system, text, details, bioc, stats, url, macos, dmrseqtgz, repository, git, clone, reports, code,
Topics {✒️}
org/packages/dmrseq source repository analyzing bisulfite-seq data bioconductor release tgz source repository source package european bioconductor conference release //code genome bisulfite sequencing bioconductor support site differentially methylated regions perform accurate inference comparing detected regions pooled null distribution region-level statistics transformed methylation proportions script reference manual gz windows binary zip macos binary tgz macos binary package implements package installed git clone https keegan korthauer [cre yuval benjamini [aut] details biocviews splines system requirements packages package started install aut] orcid irizarry ra bioconductor //bioconductor org registration open quietly = true older versions pdf news bsseq imports developer access text license released version devel version wholegenome version regression model view documentation url download stats install
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