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Title:
Bioconductor - dce
Description:
Compute differential causal effects (dce) on (biological) networks. Given observational samples from a control experiment and non-control (e.g., cancer) for two genes A and B, we can compute differential causal effects with a (generalized) linear regression. If the causal effect of gene A on gene B in the control samples is different from the causal effect in the non-control samples the dce will differ from zero. We regularize the dce computation by the inclusion of prior network information from pathway databases such as KEGG.
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Keywords {🔍}
bioconductor, package, packages, dce, version, causal, release, pathway, differential, effects, source, started, samples, control, network, philipp, jablonski, enter, install, reports, binary, learn, developers, software, compute, noncontrol, cancer, regression, effect, gene, databases, kegg, kim, aut, martin, pirkl, installation, start, documentation, system, html, script, details, bioc, stats, url, macos, repository, git, clone,
Topics {✒️}
/cbg-ethz/dce bug reports org/packages/dce source repository joint galaxy/bioconductor conference /cbg-ethz/dce/issues date release version bioconductor release source package differential causal effects source repository //code bioconductor support site pathway enrichment based release script reference manual prior network information gz windows binary git clone https details biocviews shadowtext system requirements package installed pathway network databases control experiment control samples control samples packages package started install pathway databases control causal effect dce computation script overview bioconductor //bioconductor macos binary registration open observational samples cre] orcid quietly = true older versions pdf news gpl-3 depends developer access statisticalmethod version 1093/bioinformatics/btab847 linear regression view documentation url download stats install
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