SUPPORT . BIOCONDUCTOR . ORG {}

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Keywords {🔍}

ago, genes, analysis, question, comment, hour, users, popular, votes, issue, background, enrichment, faq, tags, replies, views, imcdatasets, months, james, macdonald, result, heatmap, matrix, answer, derived, applying, lmfit, ebayes, toptable, modeling, associations, nmr, perform, differential, expression, lncrnas, deseq, united, states, log, sign, latest, news, jobs, tutorials, limit, time, today, week, month,

Topics {✒️}

gene set/pathway scoring variance-driven patterns logfc values compare basic regression model � votes handling large data site constitutes acceptance 1 hour ago replies comment similar algor answer 1822 users visited popular question united states test set enrichment analysis background genes top 20 genes time today year unanswered good features applying lmfit modeling associations [limma user' binary predictors avoid artifacts 2k locations • user agreement privacy policy io/ comment differe… comment soft… comment count matrix faq heatmap analysis derived melbourne australia genes � answer result comment matrix log sign week month james 1 recent issue

Questions {❓}

• > How do these logFC values compare to standard effect sizes derived using a basic regression model like lm()?
• Best practice for handling large data (matrix with >2^31-1 non-zero elements) in SingleCellExperiment?

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