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Title:
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease - PubMed
Description:
Bcl-2 belongs to a family of apoptosis-regulatory proteins which incorporate into the outer mitochondrial as well as nuclear membranes. The mechanism by which the proto-oncogene product Bcl-2 inhibits apoptosis is thus far elusive. We and others have shown previously that the first biochemical alter …
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Keywords {🔍}
mitochondrial, doi, pmid, cell, apoptosis, pubmed, bcl, mitochondria, kroemer, pmc, cells, aif, permeability, transition, death, review, articles, cited, mesh, protease, susin, zamzami, hirsch, apoptotic, free, article, pharmacology, main, ncbi, similar, references, information, resources, exp, med, jem, release, apoptogenic, marchetti, proteins, nuclear, protooncogene, membrane, delta, psi, protein, isolated, marzo, sep, feb,
Topics {✒️}
similar articles cited apoptosis-regulatory proteins main page content n-benzyloxycarbonyl-val-ala-asp apoptogenic protease oncogene interleukin-1 beta-converting enzyme bcl-2 prevents apoptosis cited mol cell biol bcl-2-hyperexpressing cells pre-apoptotic delta psi independent cell death mesh keyword bcl-2 inhibits nucleus apoptosis-inducing factor apoptosis-necrosis paradox stress-induced apoptosis cells undergoing apoptosis literature sources purified protein complexes hiv-1 viral protein cell biol bcl-2 hyperexpressed cell-free cell death united states government biochemical alteration detectable internucleosomal dna fragmentation books pubchem compound apoptotic death cascades cell line outer mitochondrial membrane bcl-2 apoptogenic proteases activated central role induces apoptosis outer mitochondrial resources pubmed wordmark pubmed logo delta psi mitochondrial products mitochondrial megachannel mitochondrial control mitochondrial function apoptotic cascade undergo apoptotic linkout
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