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Title:
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis - PubMed
Description:
In a number of experimental systems, the early stage of the apoptotic process, i.e. the stage which precedes nuclear disintegration, is characterized by the breakdown of the inner mitochondrial transmembrane potential (delta psi m). Here we address the question as to whether mitochondrial permeabili …
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Keywords {🔍}
doi, mitochondrial, pmid, apoptosis, permeability, delta, psi, transition, free, article, pmc, disruption, kroemer, apoptotic, mitochondria, pharmacology, articles, mesh, zamzami, marchetti, hirsch, susin, bongkrekic, acid, drug, effects, main, ncbi, similar, cited, resources, potential, castedo, pubmed, feb, review, physiology, hhs, page, content, homepage, navigation, search, full, text, abstract, publication, types, terms, substances,
Topics {✒️}
analogue n-methyl-val-4-cyclosporin bongkrekic acid main page content immunosuppressive cyclosporin similar articles cited mitochondrial membrane mesh keyword immunoglobulin g-dependent enhancement heart mitochondria exposed mitochondrial permeability transition permeability transition interfere resources febs lett cyclosporin-sensitive pore bax-dependent apoptosis apoptosis-inhibitory effect isolated mitochondria mitochondria pathways pt-mediated delta psi literature sources lymphocyte apoptosis mitochondrial transmembrane potential united states government precedes nuclear disintegration purified protein complexes flow cytometric analysis hl-cms systems nuclear factor kappab clin cancer res pt-inhibitory potential apoptotic delta psi central coordinating event prevent apoptosis induces apoptosis cited cyclosporin delta psi pubmed wordmark pubmed logo apoptosis mitochondrial megachannel mitochondrial activation mitochondrial populations hhs experimental systems critical event central role mol cancer kappab kinase linkout apoptotic process
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