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Title:
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c - PubMed
Description:
A cell-free system based on cytosols of normally growing cells is established that reproduces aspects of the apoptotic program in vitro. The apoptotic program is initiated by addition of dATP. Fractionation of cytosol yielded a 15 kDa protein that is required for in vitro apoptosis. The absorption s β¦
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Keywords {π}
cytochrome, doi, pmid, apoptotic, free, article, protein, apoptosis, pmc, extracts, cells, cytosol, metabolism, cited, cell, program, kim, articles, mesh, cellfree, wang, mitochondria, review, epub, group, main, ncbi, similar, resources, sequence, pubmed, caspase, caspases, triphosphate, science, feb, human, drug, effects, dna, hela, hhs, page, content, homepage, navigation, search, full, text, abstract,
Topics {βοΈ}
cell-free system based main page content similar articles cited cells undergoing apoptosis colon cancer cells cell-free extracts protein sequence revealed books gene medgen resources cell growing cells literature sources cytosol yielded cytosol preparation mesh keyword 2-chloro-2'-deoxyadenosine 5'-triphosphate distinct caspases cytosol apoptosis induced caspase-8 apoptotic program adding back cytochrome united states government micellar concentration dependence metzinger-le meuth biol inorg chem pparΞ³-binding protein potent therapeutic agent environ health toxicol human cytochrome pubmed wordmark pubmed logo acad sci cited protein protein human services vitro apoptosis releasing cytochrome 15 kda protein apoptotic activity hhs linkout apoptosis 9027314 apoptosis official website reproduces aspects absorption spectrum direct inhibition deveraux ql stennicke hr van arsdale
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