
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands - PubMed
Description:
The mitochrondrial benzodiazepine receptor (mBzR) binds a subset of benzodiazepines and isoquinoline carboxamides with nanomolar affinity and consists of the voltage-dependent anion channel, the adenine nucleotide translocator, and an 18-kDa protein. The effect of ligands of the mBzR on two inner mi …
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Keywords {🔍}
doi, mitochondrial, pmid, pubmed, channel, pmc, feb, receptor, mbzr, pharmacology, drug, effects, benzodiazepine, membrane, channels, free, article, bioenerg, biomembr, review, epub, physiology, similar, articles, mesh, ion, activities, protoporphyrin, activity, heart, main, states, ncbi, cited, references, resources, pnas, nanomolar, ligands, mcenery, affinity, voltagedependent, anion, translocator, protein, mcc, mcts, concentrations, clonazepam, association,
Topics {✒️}
membrane ion channels outer membrane channels united states government main page content similar articles cited funding linkout mesh keyword membrane channel activity voltage-dependent anion channel clonazepam sprague-dawley receptors literature sources biochim biophys acta nanomolar actions protoporphyrin ix mitochrondrial benzodiazepine receptor mitochondrial benzodiazepine receptor ischemic heart disease adenine nucleotide translocator mitochondrial translocator protein hhs multiple conductance channel 1374 abstract patch-clamp techniques relative inhibitory potencies adenine nucleotide carrier mitochondrial centum-picosiemen similar levels vitro catabolic effect cited low mbzr affinity 18-kda protein oxidative stress research support channel activities mcts activity pubmed wordmark pubmed logo inhibits mcc [3h]ro5-4864 grants mitochondrial criticality mitochondrial origin low affinity nanomolar affinity official website isoquinoline carboxamides drugs resemble binding affinities nanomolar concentrations
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