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Title:
Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A - PubMed
Description:
<p>Mitochondria from a variety of sources possess a regulated inner membrane channel, the permeability transition pore (MTP), which is responsible for the
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Keywords {🔍}
doi, permeability, pore, pmid, mitochondrial, transition, cyclosporin, bernardi, mtp, potential, mitochondria, membrane, effects, pmc, petronilli, free, article, drug, articles, mesh, channel, colonna, gating, asensitive, review, cell, acid, main, ncbi, similar, cited, resources, biophys, regulated, probability, matrix, opening, reversible, biol, voltage, pubmed, oct, death, liver, hhs, page, content, homepage, navigation, search,
Topics {✒️}
main page content similar articles cited effects rat liver demonstrated internal membranes mesh keyword voltage-dependent channel blocked oxidation-reduction state affects permeability transition pore pore open-closed probability mitochondrial permeability transition cyclosporin-sensitive pore sudden permeability increase sources possess membrane channel 'permeability transition' mitochondrial membrane calcineurin-dependent pathway voltage sensor comprises biochim biophys acta pore opening increases pore opening/closure mitochondrial transmembrane potential isolated mitochondria membrane potential united states government biological cells exposed delmas-beauvieux mc reactive oxygen species necrotic cell death mol cell cardiol present recent work mtp open probability gating potential increases mtp gating potential reversible histidine protonation gating potential decreases mitochondria cited membrane cell death voltage inducement mitochondrial cyclophilin mitochondrial biology mitochondrial dysfunction pathological effectors gating potential sequential reduction pubmed wordmark pubmed logo
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