
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification - PubMed
Description:
This study established an ALKBH5-PKMYT1-IGF2BP3 regulation system in metastasis, representing a new therapeutic target for GC metastasis.
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27 years and 8 months (reg. 1997-10-02).
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Keywords {🔍}
cancer, alkbh, pmc, metastasis, doi, zhang, wang, pmid, gastric, pubmed, free, article, demethylase, pkmyt, rna, liu, protein, fig, zhu, invasion, chen, articles, mesh, yang, human, expression, cell, target, gene, zhou, kinases, main, ncbi, search, authors, figures, similar, cited, references, related, information, resources, mol, modification, luo, activity, manner, igfbp, mrna, stability,
Topics {✒️}
main page content resources mol cancer m6 a-ythdf2-dependent manner alkbh5-pkmyt1-igf2bp3 regulation system biomed res int rna demethylase alkbh5 pi3k-akt signaling pathway quantitative real-time pcr myelodysplastic neoplasms stomach adenocarcinoma m6a regulator-based signature alkbh5-mediated m6a modification medgen protein health mesh keyword m6a demethylase alkbh5 articles references rawla methylation-related signature protein similar articles cited mrna stability demethylase activity mutation rna immunoprecipitation abstract background harm human healthcare authors declare m6a-dependent manner rna-seq m6a modification site igf2bp3 helped stabilize cell death dis rna pulldown setbp1-mediated activation acetylation-dependent stabilization pubmed kim pubmed wordmark pubmed logo united states government stability van grieken nc alkbh5 modulates expression failed cancer treatment gastrointestinal tract cancer merip-qrt-pcr lincrna linc02551 enhances stabilising jak1 mrna demethylase activity lung metastasis model lymph node metastasis target gene
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