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Title:
The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotection - PubMed
Description:
The mitochondrial permeability transition (PT) - an abrupt increase permeability of the inner membrane to solutes - is a causative event in ischemia-reperfusion injury of the heart, and the focus of intense research in cardioprotection. The PT is due to opening of the PT pore (PTP), a high conductan …
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Keywords {🔍}
mitochondrial, doi, permeability, pmid, transition, pmc, pubmed, article, mitochondria, free, review, pore, nih, states, epub, synthase, atp, metabolism, articles, mesh, cell, sep, heart, ptp, hhsunited, main, ncbi, similar, cited, references, substances, grants, resources, mol, jan, jyjmcc, molecular, role, membrane, ischemiareperfusion, injury, research, sci, aug, feb, cells, biol, chem, drug, effects,
Topics {✒️}
united states government mitochondrial permeability transition main page content permeability transition pore heart mitochondrial proteome pubmed show similar articles cited hhs funding linkout basic mitochondrial biology mitochondrial atp synthase articles references raaflaub membrane anti-apoptotic therapeutic strategies literature sources mitochondrial-atpase abrupt increase permeability f-atp synthase contributes resources review mesh keyword pt pore reduced oxygen utilization extramural research support 023 abstract ischemia-reperfusion injury high conductance channel special issue entitled ischemia–reperfusion injury authors peripheral stalk subunits voltage-dependent regulation copper dependent modulation α-synuclein phosphorylation human mitochondria persists f-atp synthase heart energy-dissipating device fo atp synthase molecular docking studies mol cell cardiol diabetes metab disord di lisa transition cardioprotection paolo bernardi 1 cited pubmed raaflaub elsevier liver mitochondria pubmed hunter pubmed tapley
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