
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release - PubMed
Description:
Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of potentially damaging levels of reactive oxygen species (ROS), Ca(2+), etc., which must be normalized. Evidence suggests that brief mitochondrial permeability transition pore (mPTP) openings play an important physiol …
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Keywords {🔍}
mitochondrial, ros, pmc, doi, oxygen, release, pmid, mitochondria, pubmed, reactive, species, free, article, review, metabolism, figure, rosinduced, mptp, role, oct, articles, permeability, transition, pore, membrane, rirr, cells, main, ncbi, figures, similar, cited, references, mesh, resources, levels, physiological, adaptive, aging, central, epub, calcium, nih, hhs, page, content, states, homepage, navigation, search,
Topics {✒️}
normal mitochondrial metabolism reactive oxygen species membrane anion channel main page content mechanisms involving calcium similar articles cited redox stress mitochondrial ros production involve mitochondrial channels heightened mitochondrial respiration mitochondrial ros formation mitochondrial rirr highlights literature sources comprehensive cross-sectional analysis reversible ca2+-induced permeabilization mitochondrial δψ redox-sensitive enzymes involved united states government intramural research support articles references mitochondria-formed ros rat brain mitochondria rat liver mitochondria induced ros release american physiological society central role potentially damaging levels protective signaling pathways higher ros levels ros-producing sites funding linkout intermitochondrial redox-environment reversible mptp opening activate local pools limit ischemic damage nadh fluorescence emission ukr biokhim zh antioxid redox signal jarosz-griffiths hh atherosclerotic cardiovascular disease nadph oxidase nox4 man'kovskaia yn ros burst leading biochim biophys acta figures adaptive housekeeping function longer mptp openings q-cycle model cited damaged mitochondria
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