
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)) - PubMed
Description:
Translocator protein of 18 kDa (TSPO) is a highly conserved, ubiquitous protein localized in the outer mitochondrial membrane, where it is thought to play a key role in the mitochondrial transport of cholesterol, a key step in the generation of steroid hormones. However, it was first characterized a β¦
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Keywords {π}
mitochondrial, tspo, doi, protein, pmid, translocator, pubmed, review, permeability, pmc, role, transition, kda, ptp, gene, figure, metabolism, epub, membrane, med, articles, cited, chem, regulation, pore, ligands, cell, biology, steroidogenesis, papadopoulos, free, article, nih, receptors, gaba, main, states, ncbi, figures, similar, references, mesh, resources, outer, benzodiazepine, receptor, transport, generation, number, pathological,
Topics {βοΈ}
united states government mitochondrial permeability transition main page content mitochondrial transport bone metabolism funding linkout outer mitochondrial membrane similar articles cited books gene gene articles references fan mitochondrial translocator protein peripheral benzodiazepine receptor control mice outer membrane hhs mice antitumor ether lipid molecular biology extramural research support gene knockout actions tspo gene elizabeth blachly-dysonΒ 2 fabio di lisaΒ 1 high affinity binding ischemia-reperfusion injury host-defense response ischemic heart disease alkylphospholipid analog edelfosine ubiquitous protein localized curr pharm des obtain highly potent steroid hormone synthesis 18-kda translocator protein resources human pathological conditions regulate ptp activity ptp activity occurs figures studies implicating tspo star biology hearts lacking tspo cited pubmed wordmark pubmed logo translocator protein biomedical research med chem human steroidogenesis grants
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