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Title:
Structural and functional evolution of the translocator protein (18 kDa) - PubMed
Description:
Translocator proteins (TSPO) are the products of a family of genes that is evolutionarily conserved from bacteria to humans and expressed in most mammalian tissues and cells. Human TSPO (18 kDa) is expressed at high levels in steroid synthesizing endocrine tissues where it localizes to mitochondria …
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Keywords {🔍}
proteins, tspo, doi, protein, pmid, pmc, free, article, receptors, review, metabolism, translocator, human, chemistry, genetics, functions, articles, kda, liu, epub, molecular, molecules, archaeal, bacterial, fungal, plant, cytoplasmic, nuclear, gaba, main, ncbi, similar, cited, mesh, related, resources, mol, papadopoulos, conserved, bacteria, tissues, steroid, cholesterol, pubmed, sci, nih, sequence, hhs, page, content,
Topics {✒️}
tryptophan-rich sensory proteins oxygen-mediated metabolism main page content similar articles cited molecular simulation study evolutionarily conserved protein united states government functional evolution extramural research support evolutionarily conserved humans gaba tspo protein human tspo2 protein funding linkout translocator protein tspo human polymorphism impair trends endocrinol metab functional oligomerization state organelle-specific functions endogenous tspo ligands translocator protein protein sci nuclear receptors health hhs intratesticular testosterone cited tertiary receptors specialized tissue review human tspo human services mol sci pubmed wordmark pubmed logo mammalian tissues steroid formation cancerous tissues steroid synthesis protein synthetic ligands elusive functions official website high levels tspo expression tissue injury mitochondrial integrity recently identified classes aves tspo homologs
Questions {❓}
- Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?
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