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Title:
Shedding light on the mitochondrial permeability transition - PubMed
Description:
The mitochondrial permeability transition is an increase of permeability of the inner mitochondrial membrane to ions and solutes with an exclusion size of about 1500Da. It is generally accepted that the permeability transition is due to opening of a high-conductance channel, the permeability transit β¦
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Keywords {π}
mitochondrial, permeability, transition, pmid, review, doi, pore, free, article, pmc, epub, membrane, role, articles, mesh, porphyrins, singlet, oxygen, main, ncbi, similar, cited, information, resources, biophys, jbbabio, ricchelli, bernardi, pubmed, feb, apr, zhang, cell, ecollection, pubchem, hhs, page, content, homepage, navigation, search, full, text, abstract, publication, types, terms, substances, related, linkout,
Topics {βοΈ}
main page content similar articles cited singlet oxygen generated singlet oxygen produced permeability transition pore gaba tspo protein mitochondrial permeability transition mitochondrial membrane hematoporphyrin-mediated photooxidative stress discrete mitochondrial domains mitochondrial targeting therapeutics shedding light patho-physiology specific porphyrins biochim biophys acta permeability transition porphyrins arch biochem biophys united states government high-conductance channel peripheral benzodiazepine receptor novartis found symp jimenez-del-rio mesh keyword mitochondrial disorders review specifically covers cns neurosci ther human services cited permeability oxidative stress front pharmacol hhs pubmed wordmark pubmed logo official website justina sileikytΔ exclusion size generally accepted great deal chemical modification specific residues basic principles photodynamic effect unique properties cys residues rights reserved photodynamic action 11368348 apoptosis induction photosensitizer verteporfin
Questions {β}
- What is the nature of the mitochondrial permeability transition pore and what is it not?
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