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Title:
Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model - PubMed
Description:
Cyclosporine A (CsA) has been shown to protect against myocardial ischemia and reperfusion (I/R) injury in small animal models. The aim of the current study was to evaluate the effects of CsA on myocardial I/R injury in a porcine model. Pigs were randomized between CsA (10mg/kg; n = 12) or placebo ( …
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Keywords {🔍}
doi, myocardial, pmid, proteins, cyclosporine, reperfusion, injury, csa, mitochondrial, model, isoflurane, epub, pmc, pharmacol, porcine, ischemia, effects, pentobarbital, review, free, article, articles, mesh, cardiovasc, jun, factor, pharmacology, metabolism, membrane, main, ncbi, similar, cited, information, resources, ther, reduce, infarct, size, ischemiareperfusion, karlsson, grip, pigs, placebo, anesthetized, protein, caspase, isaar, pubmed, apr,
Topics {✒️}
apoptosis-inducing factor [aif] myocardial reperfusion injury small animal models proapoptotic proteins postischemic reperfused myocardium acute ischemia/reperfusion injury ischemia/reperfusion injury cardioprotective effects pentobarbital effects myocardial ischemia myocardial biopsies isoflurane main page content myocardial similar articles cited active caspase-3 injury mesh keyword reperfusion cardiovascular research health united states government alex-xianghua zhou karin aström-olsson interleukin-1 receptor antagonist acta anaesthesiol scand cholesteryl esters accumulate 2nd international symposium cabrera-fuentes ha salinas-estefanon em resources cell death pathways basic res cardiol cardiovasc pharmacol ther sanchez-vega jt cited cyclosporine infarct size cardiovasc res porcine model pubmed wordmark pubmed logo hhs cardiovascular system vivo model death receptors pharmacol rev official website chrichan månsson
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