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Title:
NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPase - PubMed
Description:
Bz-423 is an inhibitor of the mitochondrial F(1)F(0)-ATPase, with therapeutic properties in murine models of immune diseases. Here, we study the binding of a water-soluble Bz-423 analog (5-(3-(aminomethyl)phenyl)-7-chloro- 1-methyl-3-(naphthalen-2-ylmethyl)-1H-benzo][e][1,4]diazepin-2(3H)-one); (1) …
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Keywords {🔍}
doi, mitochondrial, pmid, binding, free, oscp, article, pmc, glick, articles, mesh, benzodiazepine, molecular, target, ffatpase, opipari, protein, synthase, main, ncbi, full, text, similar, cited, resources, jan, immunomodulatory, therapeutic, enzyme, experiments, pubmed, chem, biol, apr, atp, epub, permeability, transition, pore, bernardi, giorgio, nih, benzodiazepines, metabolism, immunologic, factors, pubchem, hhs, page, content,
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