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Title:
Effect of peripheral benzodiazepine receptor (PBR/TSPO) ligands on opening of Ca2+-induced pore and phosphorylation of 3.5-kDa polypeptide in rat brain mitochondria - PubMed
Description:
The effect of nanomolar concentrations of PBR/TSPO ligands--Ro 5-4864, PK11195, and PPIX--on Ca2+-induced permeability transition pore (PTP) opening in isolated rat brain mitochondria was investigated. PBR/TSPO agonist Ro 5-4864 (100 nM) and endogenous ligand PPIX (1 microM) were shown to stimulate …
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Keywords {🔍}
doi, pmid, mitochondria, opening, protein, kda, rat, brain, tspo, pmc, metabolism, ligands, krestinina, ptp, free, article, pbrtspo, pore, reiser, azarashvili, permeability, transition, translocator, articles, mesh, cainduced, phosphorylation, grachev, odinokova, peptide, papadopoulos, cell, jul, mitochondrial, review, apoptosis, main, ncbi, similar, cited, resources, effect, benzodiazepine, receptor, evtodienko, ligand, antibody, pubmed, calcium, epub,
Topics {✒️}
main page content similar articles cited mitochondrion-dependent cell death peripheral-type benzodiazepine receptor pbr/tspo ligands action tspo-dependent phosphorylation/dephosphorylation pbr/tspo ligands--ro 5-4864 induced permeability transition peripheral benzodiazepine receptor ca2+-induced pore pbr/tspo ligands mesh keyword rat brain mitochondria pbr ligand action intact brain mitochondria resources biochemistry regulates protein phosphorylation translocator protein tspo specific anti-subunit 18-kda translocator protein cell calcium rat liver mitochondria 1134/s0006297909040105 abstract programmed cell death potential involvement united states government arch biochem biophys curr mol med host-defense response curr pharm des reactive oxygen species antineoplastic agent erucylphosphohomocholine tspo ligands endogenous ligand ppix antibody glioblastoma cell lines stimulate ptp opening pbr/tspo rat mitochondria cited ligands tspo expression nanomolar concentrations stimulate dephosphorylation hhs ptp opening pubmed wordmark pubmed logo 5-kda polypeptide 5 kda polypeptide
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