
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death - PubMed
Description:
Mitochondria are critically involved in necrotic cell death induced by Ca(2+) overload, hypoxia and oxidative damage. The mitochondrial permeability transition (MPT) pore - a protein complex that spans both the outer and inner mitochondrial membranes - is considered the mediator of this event and ha …
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Keywords {🔍}
cell, mitochondrial, vdac, metabolism, death, doi, voltagedependent, anion, pmid, permeability, pmc, transition, pubmed, mitochondria, epub, free, article, channel, states, pore, protein, membrane, role, mouse, nih, proteins, biol, channels, mpt, figure, apoptosis, articles, mesh, cells, kroemer, atp, research, rna, hlhlnhlbi, hhsunited, main, ncbi, abstract, similar, cited, references, related, grants, resources, nat,
Topics {✒️}
voltage-dependent anion channels united states government voltage-dependent anion channel mitochondrial-dependent cell death oxidative stress-induced mpt oxidative-stress-induced mpt pubmed show mitochondrial permeability transition hhs main page content funding linkout mitochondrial membranes fo atp synthase f1fo atp synthase metabolism vdac1-vdac3-null mice exhibited pro-apoptotic ca2+ signals anti-apoptotic bcl-xl adenine-nucleotide translocase extramural research support mitochondrial apoptosis mouse vdac3 protein mouse vdac2 protein mesh keyword related bcl-2 mitochondrial adp outer membrane oxidative damage exhibited equivalent cytochrome membrane calcium biomedical research pore pore biochim biophys acta van vliet ar la rovere rm mammalian vdac genes nat cell biol rat liver mitochondria fibroblasts lacking vdac1 similar articles cited � comment critical control points vdac-deficient mitochondria mitochondria-mediated neurodegeneration cell death similar articles role vdac1-vdac2-vdac3 wild-type mitochondria
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