
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling - PubMed
Description:
Rhomboids, evolutionarily conserved integral membrane proteases, participate in crucial signaling pathways. Presenilin-associated rhomboid-like (PARL) is an inner mitochondrial membrane rhomboid of unknown function, whose yeast ortholog is involved in mitochondrial fusion. Parl-/- mice display norma β¦
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Keywords {π}
mitochondrial, doi, parl, pmid, opa, apoptosis, free, article, pmc, metabolism, cell, jul, protein, mitochondria, genetics, jcell, scorrano, epub, display, articles, cited, mesh, mice, death, review, proteins, main, ncbi, similar, resources, rhomboid, cytochrome, cristae, remodeling, membrane, cells, apoptotic, pubmed, biophys, oct, research, gtp, phosphohydrolases, metalloproteases, mouse, gene, hhs, page, content, access,
Topics {βοΈ}
mitochondria-shaping proteins main page content mitochondrial membrane rhomboid metalloproteases parl protein / metabolism cultured cytochromes mitochondrial morphology inbred c57bl mice mitochondria mitochondrial fusion mitochondrial adaptation mitochondrial injury postnatal growth restriction rhomboid serine proteases martins de brito mesh keyword human parl protein opa1 specifically targeted united states government luciano d'adamio rudi d'hooge crucial signaling pathways sanjuΓ‘n szklarz lk novartis found symp higd-1a interacts medgen nucleotide omim biochim biophys acta resources cell funding linkout similar articles cited de strooper cell death differ intramembrane proteolysis protein protein biomedical research similar articles regulation opa1 processing hhs cachectic death atrophy grants human services increased apoptosis controlling apoptosis pubmed wordmark pubmed logo official website dieter hartmann veronica costa
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