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Title:
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission - PubMed
Description:
Mitochondrial fission requires the evolutionarily conserved dynamin related protein (DRP1), which is recruited from the cytosol to the mitochondrial outer membrane to coordinate membrane scission. Currently, the mechanism of recruitment and assembly of DRP1 on the mitochondria is unclear. Here, we i …
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Keywords {🔍}
mitochondrial, sumo, doi, pmid, drp, epub, free, article, pmc, fission, mitochondria, sumoylation, cell, articles, protein, ubc, microscopy, ubiquitinconjugating, main, ncbi, abstract, similar, cited, mesh, resources, feb, zunino, mcbride, pubmed, apr, human, nov, rep, death, review, embo, metabolism, hhs, page, content, homepage, navigation, search, full, text, publication, types, terms, substances, linkout,
Topics {✒️}
main page content similar articles cited video microscopy demonstrates sumo protease senp5 sumo modification transient transfection identify ubc9 specific drp1-interacting proteins ubc9 curr med chem fluorescence microscopy revealed united states government coordinate membrane scission sumoylation targeting mitophagy mitochondrial outer membrane ischemic neuronal death substrate sumoylation specificity common mitochondrial modification fragmented mitochondria apoptotic cell death total cytosolic yfp abstract sumo1 dramatically increases endogenous drp1 levels mol cell proteomics maintain mitochondrial morphology endogenous mitochondrial drp1 cited leukemia cells mitochondrial fission fluorescence microscopy mitochondria cell biol cell death mcbride hm akt phosphorylation mol med sumo1 conjugates mitochondrial fractions mitochondrial fragmentation mitochondrial proteome mitochondrial biogenesis mitochondrial fusion hhs pubmed wordmark pubmed logo sumo1 substrate cell sci mitochondrial assembly official website
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