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Title:
The mitochondrion in apoptosis: how Pandora's box opens - PubMed
Description:
There is widespread agreement that mitochondria have a function in apoptosis, but the mechanisms behind their involvement remain controversial. Here we suggest that opening of a multiprotein complex called the mitochondrial permeability transition pore complex is sufficient (and, usually, necessary) …
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Keywords {🔍}
doi, pmid, mitochondrial, apoptosis, physiology, review, cell, mitochondria, pmc, articles, cited, epub, free, article, protooncogene, proteins, main, ncbi, abstract, similar, mesh, resources, biol, jan, complex, pubmed, martinou, protein, voltagedependent, anion, channels, hhs, page, content, homepage, navigation, search, full, text, publication, types, terms, substances, related, information, linkout, nat, rev, mol, kroemer,
Topics {✒️}
main page content similar articles cited protein mitochondrial adp purified protein complexes bcl-2 bcl literature sources multiprotein complex called united states government involvement remain controversial controlling ca²⁺ overload acute kidney injury mitochondrial complex cell death books linkout mitochondrial pathway biol reprod cited 1038/35048073 abstract abstract triggering apoptosis cell sci mitochondrial gate mitochondrial barrier mitochondrial megachannel mitochondrial permeabilization isolated mitochondria suh hs intact cells mouse heart pubmed wordmark pubmed logo hhs 11413467 review 9755823 review review ischemic injury official website apoptosis box opens widespread agreement martinou jc nature green dr central role evidence obtained biomed pharmacother lucken-ardjomande takagi-morishita de pedro
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