
PMC . NCBI . NLM . NIH . GOV {
}
Title:
Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria - PMC
Description:
Bax is a Bcl-2-family protein with pro-apoptotic activity that can form channels in lipid membranes. The protein has been shown to trigger cytochrome c release from mitochondria both in vitro and in vivo. Recombinant human Bax isolated in the ...
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Keywords {🔍}
doi, pubmed, google, scholar, bax, pmc, article, bcl, apoptosis, free, cell, biol, cytochrome, mitochondria, nlm, release, protein, korsmeyer, activity, martinou, ncbi, search, antonsson, monomeric, nature, channelforming, montessuit, aug, jcb, oct, proc, natl, acad, sci, pnas, reed, jan, human, isolated, references, science, hsu, youle, bclxl, apr, chem, jbc, thompson, required, liposomes,
Topics {✒️}
bcl-xl-bak peptide complex apaf-1/caspase-9 complex initiates displayed channel-forming activity pmc beta search bid-induced conformational change bax channel-forming activity channel-forming activity cell-free apoptosis full text aeromonas toxin proaerolysin human bcl-xl license information pmcid pro-apoptotic activity membrane-channel states ion channel characteristics protein bcl-2 alpha pmc disclaimer united states government n-dedecyl maltoside permeability transition pore basic biological phenomenon wide-ranging implications apoptotic protease cascade organelle fraction enriched selected references require membrane attachment protein expr purif bcl-2-family protein proto-oncogene bcl-2 datp-dependent formation xenopus egg extracts bax function independently apparent molecular mass bcl-2-family proteins bax-induced cytochrome regulate cell death outer mitochondrial membranes synthetic lipid membranes programmed cell death bax-induced release bcl-2-related proteins soluble monomeric protein activated monomeric bax antiapoptotic protein bcl-2 trends cell biol search log biochemical journal article articles links channel formation
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